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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review)

Gangduo Wang, Eddie Reed, Qingdi Q. Li
Pages: 955-965
Published online on: 01 November 2004

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Article

Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions

Manabu Matsumoto, Yuji Ohtsuki, Kenji Ochii, Yasushi Seike, Norihiro Iseda, Toyokazu Sasaki, Yuhei Okada, Atsushi Kurabayashi, Mutsuo Furihata
Pages: 967-971
Published online on: 01 November 2004

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Dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine S-1 may be effective against peritoneal dissemination in gastric cancer

Shigehito Yamagata, Bunzo Nakata, Kosei Hirakawa
Pages: 973-978
Published online on: 01 November 2004

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Loss of estrogen receptor β expression at cancer front correlates with tumor progression and poor prognosis of gallbladder cancer

Kenji Sumi, Satoru Matsuyama, Yoshihiko Kitajima, Kohji Miyazaki
Pages: 979-984
Published online on: 01 November 2004

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Article

Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality

Reiko Ito, Hirofumi Nakayama, Kazuhiro Yoshida, Noriko Oda, Wataru Yasui
Pages: 985-990
Published online on: 01 November 2004

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Article

Orthotopically implanted SCID mouse model of human lung cancer suitable for investigating metastatic potential and anticancer drug effects

Kazuya Kondo, Haruhiko Fujino, Takanori Miyoshi, Hisashi Ishikura, Shoji Sakiyama, Yasumasa Monden
Pages: 991-999
Published online on: 01 November 2004

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Expression of human kallikrein 7 (hK7/SCCE) and its inhibitor antileukoprotease (ALP/SLPI) in uterine endocervical glands and in cervical adenocarcinomas

Xiurong Tian, Kazushi Shigemasa, Eiji Hirata, Lijun Gu, Yoshimi Uebaba, Nobutaka Nagai, Timothy J. O'Brien, Koso Ohama
Pages: 1001-1006
Published online on: 01 November 2004

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Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line

M. Lahiri, J. H.J. Martin
Pages: 1007-1011
Published online on: 01 November 2004

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Article

Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder

Kohei Shibata, Kazuhiro Yada, Toshifumi Matsumoto, Atsushi Sasaki, Masayuki Ohta, Seigo Kitano
Pages: 1013-1016
Published online on: 01 November 2004

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Hepatocyte growth factor and c-Met immunoreactivity are associated with metastasis in high grade salivary gland carcinoma

Keiichi Tsukinoki, Masanori Yasuda, Yusuke Mori, Shigeyuki Asano, Hiroyuki Naito, Yoshihide Ota, R. Yoshiyuki Osamura, Yoshihisa Watanabe
Pages: 1017-1021
Published online on: 01 November 2004

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Reversal of multidrug-resistance using Valspodar® (PSC 833) and doxorubicin in osteosarcoma

E. Cagliero, R. Ferracini, E. Morello, K. Scotlandi, M. C. Manara, P. Buracco, A. Comandone, R. Baroetto Parisi, N. Baldini
Pages: 1023-1031
Published online on: 01 November 2004

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Single nucleotide polymorphism in the hypoxia-inducible factor-1α gene in colorectal carcinoma

Toshio Kuwai, Yasuhiko Kitadai, Shinji Tanaka, Tsuyoshi Kuroda, Takehiko Ochiumi, Shunji Matsumura, Naohide Oue, Wataru Yasui, Mika Kaneyasu, Keiji Tanimoto, Masahiko Nishiyama, Kazuaki Chayama
Pages: 1033-1037
Published online on: 01 November 2004

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Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors

Manabu Matsumoto, Mutsuo Furihata, Atsushi Kurabayashi, Yuji Ohtsuki
Pages: 1039-1043
Published online on: 01 November 2004

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Humoral response to p53 is associated with conserved domains II and IV mutations in human colorectal cancer: A case-control study in Taiwan

Chi-Ming Wu, Reiping Tang, Jim-Ray Chen, Meng-Chih Wu, Huei-Tzu Chien, Chung Rong Changchien, Ling-Ling Hsieh
Pages: 1045-1051
Published online on: 01 November 2004

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Article

Small cell lung cancer cells express EGFR and tyrosine phosphorylation of EGFR is inhibited by gefitinib (‘Iressa’, ZD1839)

Sachie Tanno, Yoshinobu Ohsaki, Kyoko Nakanishi, Eri Toyoshima, Kenjiro Kikuchi
Pages: 1053-1057
Published online on: 01 November 2004

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A multi-center, late phase II clinical trial of Genexol® (paclitaxel) and cisplatin for patients with advanced gastric cancer

Sook Ryun Park, Do-Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Noe Kyeong Kim, Won Ki Kang, Heung-Tae Kim, Seock-Ah Im, Jae-Hong Suh, Hark-Kyun Kim, Hoon-Kyo Kim
Pages: 1059-1064
Published online on: 01 November 2004

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The effectiveness of artificial neural networks in evaluating treatment plans for patients requiring external beam radiotherapy

Bo Lennernäs, Dan Sandberg, Per Albertsson, Åke Silén, Ulf Isacsson
Pages: 1065-1070
Published online on: 01 November 2004

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Involvement of 90K/Mac-2 binding protein in cancer metastases by increased cellular adhesiveness in lung cancer

Yoshitomo Ozaki, Keiichi Kontani, Koji Teramoto, Takuya Fujita, Noriaki Tezuka, Satoru Sawai, Toshinaga Maeda, Hiroyoshi Watanabe, Shozo Fujino, Tohru Asai, Iwao Ohkubo
Pages: 1071-1077
Published online on: 01 November 2004

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Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats

Naoyuki Danbara, Norihisa Uehara, Nobuaki Shikata, Hideho Takada, Takahiko Hada, Airo Tsubura
Pages: 1079-1085
Published online on: 01 November 2004

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Article

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas

Takaya Kobatake, Masaaki Yano, Shinichi Toyooka, Kazunori Tsukuda, Hideaki Dote, Takefumi Kikuchi, Minoru Toyota, Mamoru Ouchida, Motoi Aoe, Hiroshi Date, Harvey I. Pass, Hiroyoshi Doihara, Nobuyoshi Shimizu
Pages: 1087-1092
Published online on: 01 November 2004

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Article

Epstein-Barr virus-associated gastric carcinoma in Papua New Guinea

Jacob Morewaya, Chihaya Koriyama, Suminori Akiba, Ding Shan, Tetsuhiko Itoh, Yoshito Eizuru
Pages: 1093-1098
Published online on: 01 November 2004

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Article

Infrequent somatic mutations of the ICAT gene in various human cancers with frequent 1p-LOH and/or abnormal nuclear accumulation of β-catenin

Mitsuho Imai, Tsutomu Nakamura, Tetsu Akiyama, Akira Horii
Pages: 1099-1103
Published online on: 01 November 2004

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Article

Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes

Yu-Kyung Kim, Yong-Soo Kim, Hyung-Min Chung, Kwang-Hyun Baek
Pages: 1105-1108
Published online on: 01 November 2004

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Article

Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid

Ulf Vogt, Krzysztof P. Bielawski, Ulrich Bosse, Claus M. Schlotter
Pages: 1109-1114
Published online on: 01 November 2004

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Article

Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells

Takuya Ohta, Hiroki Hori, Masahiro Ogawa, Masazumi Miyahara, Hajime Kawasaki, Norihisa Taniguchi, Yoshihiro Komada
Pages: 1115-1120
Published online on: 01 November 2004

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Article

Concurrent preoperative chemoradiotherapy for stage III or IV esophageal squamous carcinoma

Yoshiaki Osaka, Yu Takagi, Akihiko Tsuchida, Sumito Hoshino, Shingo Tachibana, Motoo Shinohara, Tatsuya Aoki
Pages: 1121-1126
Published online on: 01 November 2004

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Article

Predicting recurrence and metastasis of stage II/Dukes' B colorectal cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Hiromi Ninomiya, Tomomi Kimura, Nobukazu Komatsu, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1127-1130
Published online on: 01 November 2004

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Article

Deregulation of p73 isoform equilibrium in benign prostate hyperplasia and prostate cancer

Demetrios A. Arvanitis, Emmanouel Lianos, Nikolaos Soulitzis, Demetrios Delakas, Demetrios A. Spandidos
Pages: 1131-1137
Published online on: 01 November 2004

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Article

Adenosine triphosphate (ATP) enhances the antitumor effect of etoposide (VP16) in lung cancer cells

Yoshihiro Hatta, Miki Takahashi, Yuko Enomoto, Noriaki Takahashi, Umihiko Sawada, Takashi Horie
Pages: 1139-1142
Published online on: 01 November 2004

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Article

Prognostic value of cell cycle regulator molecules in surgically resected stage I and II breast cancer

Maria Giselle Peters, Maria Del Carmen C Vidal, Liliana Giménez, Laura Mauro, Eduardo Armanasco, Carlos Cresta, Elisa Bal De Kier Joffé, Lydia Puricelli
Pages: 1143-1150
Published online on: 01 November 2004

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.m. Tong, Anthony W.h. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.c. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani‑Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

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Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

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Article Number: 164
Published online on: 24 July 2026

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