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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review)

Gangduo Wang, Eddie Reed, Qingdi Q. Li
Pages: 955-965
Published online on: 01 November 2004

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Article

Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions

Manabu Matsumoto, Yuji Ohtsuki, Kenji Ochii, Yasushi Seike, Norihiro Iseda, Toyokazu Sasaki, Yuhei Okada, Atsushi Kurabayashi, Mutsuo Furihata
Pages: 967-971
Published online on: 01 November 2004

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Article

Dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine S-1 may be effective against peritoneal dissemination in gastric cancer

Shigehito Yamagata, Bunzo Nakata, Kosei Hirakawa
Pages: 973-978
Published online on: 01 November 2004

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Article

Loss of estrogen receptor β expression at cancer front correlates with tumor progression and poor prognosis of gallbladder cancer

Kenji Sumi, Satoru Matsuyama, Yoshihiko Kitajima, Kohji Miyazaki
Pages: 979-984
Published online on: 01 November 2004

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Article

Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality

Reiko Ito, Hirofumi Nakayama, Kazuhiro Yoshida, Noriko Oda, Wataru Yasui
Pages: 985-990
Published online on: 01 November 2004

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Article

Orthotopically implanted SCID mouse model of human lung cancer suitable for investigating metastatic potential and anticancer drug effects

Kazuya Kondo, Haruhiko Fujino, Takanori Miyoshi, Hisashi Ishikura, Shoji Sakiyama, Yasumasa Monden
Pages: 991-999
Published online on: 01 November 2004

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Article

Expression of human kallikrein 7 (hK7/SCCE) and its inhibitor antileukoprotease (ALP/SLPI) in uterine endocervical glands and in cervical adenocarcinomas

Xiurong Tian, Kazushi Shigemasa, Eiji Hirata, Lijun Gu, Yoshimi Uebaba, Nobutaka Nagai, Timothy J. O'Brien, Koso Ohama
Pages: 1001-1006
Published online on: 01 November 2004

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Article

Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line

M. Lahiri, J. H.J. Martin
Pages: 1007-1011
Published online on: 01 November 2004

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Article

Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder

Kohei Shibata, Kazuhiro Yada, Toshifumi Matsumoto, Atsushi Sasaki, Masayuki Ohta, Seigo Kitano
Pages: 1013-1016
Published online on: 01 November 2004

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Article

Hepatocyte growth factor and c-Met immunoreactivity are associated with metastasis in high grade salivary gland carcinoma

Keiichi Tsukinoki, Masanori Yasuda, Yusuke Mori, Shigeyuki Asano, Hiroyuki Naito, Yoshihide Ota, R. Yoshiyuki Osamura, Yoshihisa Watanabe
Pages: 1017-1021
Published online on: 01 November 2004

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Article

Reversal of multidrug-resistance using Valspodar® (PSC 833) and doxorubicin in osteosarcoma

E. Cagliero, R. Ferracini, E. Morello, K. Scotlandi, M. C. Manara, P. Buracco, A. Comandone, R. Baroetto Parisi, N. Baldini
Pages: 1023-1031
Published online on: 01 November 2004

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Article

Single nucleotide polymorphism in the hypoxia-inducible factor-1α gene in colorectal carcinoma

Toshio Kuwai, Yasuhiko Kitadai, Shinji Tanaka, Tsuyoshi Kuroda, Takehiko Ochiumi, Shunji Matsumura, Naohide Oue, Wataru Yasui, Mika Kaneyasu, Keiji Tanimoto, Masahiko Nishiyama, Kazuaki Chayama
Pages: 1033-1037
Published online on: 01 November 2004

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Article

Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors

Manabu Matsumoto, Mutsuo Furihata, Atsushi Kurabayashi, Yuji Ohtsuki
Pages: 1039-1043
Published online on: 01 November 2004

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Article

Humoral response to p53 is associated with conserved domains II and IV mutations in human colorectal cancer: A case-control study in Taiwan

Chi-Ming Wu, Reiping Tang, Jim-Ray Chen, Meng-Chih Wu, Huei-Tzu Chien, Chung Rong Changchien, Ling-Ling Hsieh
Pages: 1045-1051
Published online on: 01 November 2004

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Article

Small cell lung cancer cells express EGFR and tyrosine phosphorylation of EGFR is inhibited by gefitinib (‘Iressa’, ZD1839)

Sachie Tanno, Yoshinobu Ohsaki, Kyoko Nakanishi, Eri Toyoshima, Kenjiro Kikuchi
Pages: 1053-1057
Published online on: 01 November 2004

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Article

A multi-center, late phase II clinical trial of Genexol® (paclitaxel) and cisplatin for patients with advanced gastric cancer

Sook Ryun Park, Do-Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Noe Kyeong Kim, Won Ki Kang, Heung-Tae Kim, Seock-Ah Im, Jae-Hong Suh, Hark-Kyun Kim, Hoon-Kyo Kim
Pages: 1059-1064
Published online on: 01 November 2004

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Article

The effectiveness of artificial neural networks in evaluating treatment plans for patients requiring external beam radiotherapy

Bo Lennernäs, Dan Sandberg, Per Albertsson, Åke Silén, Ulf Isacsson
Pages: 1065-1070
Published online on: 01 November 2004

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Article

Involvement of 90K/Mac-2 binding protein in cancer metastases by increased cellular adhesiveness in lung cancer

Yoshitomo Ozaki, Keiichi Kontani, Koji Teramoto, Takuya Fujita, Noriaki Tezuka, Satoru Sawai, Toshinaga Maeda, Hiroyoshi Watanabe, Shozo Fujino, Tohru Asai, Iwao Ohkubo
Pages: 1071-1077
Published online on: 01 November 2004

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Article

Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats

Naoyuki Danbara, Norihisa Uehara, Nobuaki Shikata, Hideho Takada, Takahiko Hada, Airo Tsubura
Pages: 1079-1085
Published online on: 01 November 2004

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Article

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas

Takaya Kobatake, Masaaki Yano, Shinichi Toyooka, Kazunori Tsukuda, Hideaki Dote, Takefumi Kikuchi, Minoru Toyota, Mamoru Ouchida, Motoi Aoe, Hiroshi Date, Harvey I. Pass, Hiroyoshi Doihara, Nobuyoshi Shimizu
Pages: 1087-1092
Published online on: 01 November 2004

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Article

Epstein-Barr virus-associated gastric carcinoma in Papua New Guinea

Jacob Morewaya, Chihaya Koriyama, Suminori Akiba, Ding Shan, Tetsuhiko Itoh, Yoshito Eizuru
Pages: 1093-1098
Published online on: 01 November 2004

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Article

Infrequent somatic mutations of the ICAT gene in various human cancers with frequent 1p-LOH and/or abnormal nuclear accumulation of β-catenin

Mitsuho Imai, Tsutomu Nakamura, Tetsu Akiyama, Akira Horii
Pages: 1099-1103
Published online on: 01 November 2004

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Article

Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes

Yu-Kyung Kim, Yong-Soo Kim, Hyung-Min Chung, Kwang-Hyun Baek
Pages: 1105-1108
Published online on: 01 November 2004

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Article

Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid

Ulf Vogt, Krzysztof P. Bielawski, Ulrich Bosse, Claus M. Schlotter
Pages: 1109-1114
Published online on: 01 November 2004

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Article

Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells

Takuya Ohta, Hiroki Hori, Masahiro Ogawa, Masazumi Miyahara, Hajime Kawasaki, Norihisa Taniguchi, Yoshihiro Komada
Pages: 1115-1120
Published online on: 01 November 2004

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Article

Concurrent preoperative chemoradiotherapy for stage III or IV esophageal squamous carcinoma

Yoshiaki Osaka, Yu Takagi, Akihiko Tsuchida, Sumito Hoshino, Shingo Tachibana, Motoo Shinohara, Tatsuya Aoki
Pages: 1121-1126
Published online on: 01 November 2004

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Article

Predicting recurrence and metastasis of stage II/Dukes' B colorectal cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Hiromi Ninomiya, Tomomi Kimura, Nobukazu Komatsu, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1127-1130
Published online on: 01 November 2004

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Article

Deregulation of p73 isoform equilibrium in benign prostate hyperplasia and prostate cancer

Demetrios A. Arvanitis, Emmanouel Lianos, Nikolaos Soulitzis, Demetrios Delakas, Demetrios A. Spandidos
Pages: 1131-1137
Published online on: 01 November 2004

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Article

Adenosine triphosphate (ATP) enhances the antitumor effect of etoposide (VP16) in lung cancer cells

Yoshihiro Hatta, Miki Takahashi, Yuko Enomoto, Noriaki Takahashi, Umihiko Sawada, Takashi Horie
Pages: 1139-1142
Published online on: 01 November 2004

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Article

Prognostic value of cell cycle regulator molecules in surgically resected stage I and II breast cancer

Maria Giselle Peters, Maria Del Carmen C Vidal, Liliana Giménez, Laura Mauro, Eduardo Armanasco, Carlos Cresta, Elisa Bal De Kier Joffé, Lydia Puricelli
Pages: 1143-1150
Published online on: 01 November 2004

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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