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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review)

Gangduo Wang, Eddie Reed, Qingdi Q. Li
Pages: 955-965
Published online on: 01 November 2004

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Article

Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions

Manabu Matsumoto, Yuji Ohtsuki, Kenji Ochii, Yasushi Seike, Norihiro Iseda, Toyokazu Sasaki, Yuhei Okada, Atsushi Kurabayashi, Mutsuo Furihata
Pages: 967-971
Published online on: 01 November 2004

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Article

Dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine S-1 may be effective against peritoneal dissemination in gastric cancer

Shigehito Yamagata, Bunzo Nakata, Kosei Hirakawa
Pages: 973-978
Published online on: 01 November 2004

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Article

Loss of estrogen receptor β expression at cancer front correlates with tumor progression and poor prognosis of gallbladder cancer

Kenji Sumi, Satoru Matsuyama, Yoshihiko Kitajima, Kohji Miyazaki
Pages: 979-984
Published online on: 01 November 2004

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Article

Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality

Reiko Ito, Hirofumi Nakayama, Kazuhiro Yoshida, Noriko Oda, Wataru Yasui
Pages: 985-990
Published online on: 01 November 2004

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Article

Orthotopically implanted SCID mouse model of human lung cancer suitable for investigating metastatic potential and anticancer drug effects

Kazuya Kondo, Haruhiko Fujino, Takanori Miyoshi, Hisashi Ishikura, Shoji Sakiyama, Yasumasa Monden
Pages: 991-999
Published online on: 01 November 2004

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Article

Expression of human kallikrein 7 (hK7/SCCE) and its inhibitor antileukoprotease (ALP/SLPI) in uterine endocervical glands and in cervical adenocarcinomas

Xiurong Tian, Kazushi Shigemasa, Eiji Hirata, Lijun Gu, Yoshimi Uebaba, Nobutaka Nagai, Timothy J. O'Brien, Koso Ohama
Pages: 1001-1006
Published online on: 01 November 2004

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Article

Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line

M. Lahiri, J. H.J. Martin
Pages: 1007-1011
Published online on: 01 November 2004

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Article

Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder

Kohei Shibata, Kazuhiro Yada, Toshifumi Matsumoto, Atsushi Sasaki, Masayuki Ohta, Seigo Kitano
Pages: 1013-1016
Published online on: 01 November 2004

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Article

Hepatocyte growth factor and c-Met immunoreactivity are associated with metastasis in high grade salivary gland carcinoma

Keiichi Tsukinoki, Masanori Yasuda, Yusuke Mori, Shigeyuki Asano, Hiroyuki Naito, Yoshihide Ota, R. Yoshiyuki Osamura, Yoshihisa Watanabe
Pages: 1017-1021
Published online on: 01 November 2004

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Article

Reversal of multidrug-resistance using Valspodar® (PSC 833) and doxorubicin in osteosarcoma

E. Cagliero, R. Ferracini, E. Morello, K. Scotlandi, M. C. Manara, P. Buracco, A. Comandone, R. Baroetto Parisi, N. Baldini
Pages: 1023-1031
Published online on: 01 November 2004

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Article

Single nucleotide polymorphism in the hypoxia-inducible factor-1α gene in colorectal carcinoma

Toshio Kuwai, Yasuhiko Kitadai, Shinji Tanaka, Tsuyoshi Kuroda, Takehiko Ochiumi, Shunji Matsumura, Naohide Oue, Wataru Yasui, Mika Kaneyasu, Keiji Tanimoto, Masahiko Nishiyama, Kazuaki Chayama
Pages: 1033-1037
Published online on: 01 November 2004

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Article

Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors

Manabu Matsumoto, Mutsuo Furihata, Atsushi Kurabayashi, Yuji Ohtsuki
Pages: 1039-1043
Published online on: 01 November 2004

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Article

Humoral response to p53 is associated with conserved domains II and IV mutations in human colorectal cancer: A case-control study in Taiwan

Chi-Ming Wu, Reiping Tang, Jim-Ray Chen, Meng-Chih Wu, Huei-Tzu Chien, Chung Rong Changchien, Ling-Ling Hsieh
Pages: 1045-1051
Published online on: 01 November 2004

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Article

Small cell lung cancer cells express EGFR and tyrosine phosphorylation of EGFR is inhibited by gefitinib (‘Iressa’, ZD1839)

Sachie Tanno, Yoshinobu Ohsaki, Kyoko Nakanishi, Eri Toyoshima, Kenjiro Kikuchi
Pages: 1053-1057
Published online on: 01 November 2004

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Article

A multi-center, late phase II clinical trial of Genexol® (paclitaxel) and cisplatin for patients with advanced gastric cancer

Sook Ryun Park, Do-Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Noe Kyeong Kim, Won Ki Kang, Heung-Tae Kim, Seock-Ah Im, Jae-Hong Suh, Hark-Kyun Kim, Hoon-Kyo Kim
Pages: 1059-1064
Published online on: 01 November 2004

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Article

The effectiveness of artificial neural networks in evaluating treatment plans for patients requiring external beam radiotherapy

Bo Lennernäs, Dan Sandberg, Per Albertsson, Åke Silén, Ulf Isacsson
Pages: 1065-1070
Published online on: 01 November 2004

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Article

Involvement of 90K/Mac-2 binding protein in cancer metastases by increased cellular adhesiveness in lung cancer

Yoshitomo Ozaki, Keiichi Kontani, Koji Teramoto, Takuya Fujita, Noriaki Tezuka, Satoru Sawai, Toshinaga Maeda, Hiroyoshi Watanabe, Shozo Fujino, Tohru Asai, Iwao Ohkubo
Pages: 1071-1077
Published online on: 01 November 2004

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Article

Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats

Naoyuki Danbara, Norihisa Uehara, Nobuaki Shikata, Hideho Takada, Takahiko Hada, Airo Tsubura
Pages: 1079-1085
Published online on: 01 November 2004

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Article

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas

Takaya Kobatake, Masaaki Yano, Shinichi Toyooka, Kazunori Tsukuda, Hideaki Dote, Takefumi Kikuchi, Minoru Toyota, Mamoru Ouchida, Motoi Aoe, Hiroshi Date, Harvey I. Pass, Hiroyoshi Doihara, Nobuyoshi Shimizu
Pages: 1087-1092
Published online on: 01 November 2004

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Article

Epstein-Barr virus-associated gastric carcinoma in Papua New Guinea

Jacob Morewaya, Chihaya Koriyama, Suminori Akiba, Ding Shan, Tetsuhiko Itoh, Yoshito Eizuru
Pages: 1093-1098
Published online on: 01 November 2004

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Article

Infrequent somatic mutations of the ICAT gene in various human cancers with frequent 1p-LOH and/or abnormal nuclear accumulation of β-catenin

Mitsuho Imai, Tsutomu Nakamura, Tetsu Akiyama, Akira Horii
Pages: 1099-1103
Published online on: 01 November 2004

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Article

Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes

Yu-Kyung Kim, Yong-Soo Kim, Hyung-Min Chung, Kwang-Hyun Baek
Pages: 1105-1108
Published online on: 01 November 2004

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Article

Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid

Ulf Vogt, Krzysztof P. Bielawski, Ulrich Bosse, Claus M. Schlotter
Pages: 1109-1114
Published online on: 01 November 2004

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Article

Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells

Takuya Ohta, Hiroki Hori, Masahiro Ogawa, Masazumi Miyahara, Hajime Kawasaki, Norihisa Taniguchi, Yoshihiro Komada
Pages: 1115-1120
Published online on: 01 November 2004

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Article

Concurrent preoperative chemoradiotherapy for stage III or IV esophageal squamous carcinoma

Yoshiaki Osaka, Yu Takagi, Akihiko Tsuchida, Sumito Hoshino, Shingo Tachibana, Motoo Shinohara, Tatsuya Aoki
Pages: 1121-1126
Published online on: 01 November 2004

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Article

Predicting recurrence and metastasis of stage II/Dukes' B colorectal cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Hiromi Ninomiya, Tomomi Kimura, Nobukazu Komatsu, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1127-1130
Published online on: 01 November 2004

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Article

Deregulation of p73 isoform equilibrium in benign prostate hyperplasia and prostate cancer

Demetrios A. Arvanitis, Emmanouel Lianos, Nikolaos Soulitzis, Demetrios Delakas, Demetrios A. Spandidos
Pages: 1131-1137
Published online on: 01 November 2004

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Article

Adenosine triphosphate (ATP) enhances the antitumor effect of etoposide (VP16) in lung cancer cells

Yoshihiro Hatta, Miki Takahashi, Yuko Enomoto, Noriaki Takahashi, Umihiko Sawada, Takashi Horie
Pages: 1139-1142
Published online on: 01 November 2004

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Article

Prognostic value of cell cycle regulator molecules in surgically resected stage I and II breast cancer

Maria Giselle Peters, Maria Del Carmen C Vidal, Liliana Giménez, Laura Mauro, Eduardo Armanasco, Carlos Cresta, Elisa Bal De Kier Joffé, Lydia Puricelli
Pages: 1143-1150
Published online on: 01 November 2004

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Article Open Access

Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Article Open Access

Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Review Open Access

Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Article Open Access

Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Article Open Access

Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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