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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2006 Volume 15 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation

Norman R. Estes II, Jaideep V. Thottassery, Francis G. Kern
Pages: 1407-1416
Published online on: 01 June 2006

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Article

Thymidylate synthase expression in oral squamous cell carcinoma predicts response to S-1

Koji Harada, Yuichiro Kawashima, Hideo Yoshida, Mitsunobu Sato
Pages: 1417-1423
Published online on: 01 June 2006

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Article

BARD1 content correlates with increased DNA fragmentation associated with muscle wasting in tumour-bearing rats

Irmgard Irminger-Finger, Sílvia Busquets, Fabrice Calabrio, Francisco J. López-Soriano, Josep M. Argilés
Pages: 1425-1428
Published online on: 01 June 2006

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Article

Chinese medicine Angelica sinensis suppresses radiation-induced expression of TNF-α and TGF-β1 in mice

Cong-Hua Xie, Ming-Sheng Zhang, Yun-Feng Zhou, Guang Han, Zhen Cao, Fu-Xiang Zhou, Gong Zhang, Zhi-Guo Luo, Jian-Ping Wu, Hui Liu, Ji Chen, Wen Jie Zhang
Pages: 1429-1436
Published online on: 01 June 2006

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Article

Robo1/Robo4: Differential expression of angiogenic markers in colorectal cancer

Jörn Gröne, Oliver Doebler, Christoph Loddenkemper, Birgit Hotz, Heinz-Johannes Buhr, Sarah Bhargava
Pages: 1437-1443
Published online on: 01 June 2006

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Article

Activation of STAT3 is a marker of poor prognosis in human colorectal cancer

Takafumi Kusaba, Toshiyuki Nakayama, Kazuyuki Yamazumi, Yuichi Yakata, Ayumi Yoshizaki, Kenichiro Inoue, Takeshi Nagayasu, Ichiro Sekine
Pages: 1445-1451
Published online on: 01 June 2006

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Article

Identification of genes linked to gefitinib treatment in prostate cancer cell lines with or without resistance to androgen: A clue to application of gefitinib to hormone-resistant prostate cancer

Seiji Yano, Hideyasu Matsuyama, Hiroshi Hirata, Ryo Inoue, Hiroaki Matsumoto, Chietaka Ohmi, Koshiro Miura, Mutsunori Shirai, Norio Iizuka, Katsusuke Naito
Pages: 1453-1460
Published online on: 01 June 2006

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Article

Siegesbeckia glabrescens induces apoptosis with different pathways in human MCF-7 and MDA-MB-231 breast carcinoma cells

Soo Young Jun, Yung Hyun Choi, Heung Mook Shin
Pages: 1461-1467
Published online on: 01 June 2006

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Article

Duodenal juice stimulates oesophageal stem cells to induce Barrett's oesophagus and oesophageal adenocarcinoma in rats

Tomoharu Miyashita, Tetsuo Ohta, Takashi Fujimura, Itasu Ninomiya, Sachio Fushida, Takanori Hattori, Koichi Miwa
Pages: 1469-1475
Published online on: 01 June 2006

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Article

Potential role of HER-2; in primary breast tumor with bone metastasis

Ryungsa Kim, Koji Arihiro, Manabu Emi, Kazuaki Tanabe, Akihiko Osaki
Pages: 1477-1484
Published online on: 01 June 2006

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Article

Chronic colitis promotes tumor development

Masaru Shinozaki, Toshiaki Watanabe, Hajime Sato, Hirokazu Nagawa
Pages: 1485-1490
Published online on: 01 June 2006

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Article

Relation of DNA ploidy to genetic aberrations detected by chromosomal CGH and FISH in gastric adenocarcinomas

Tomoko Furuya, Tetsuji Uchiyama, Atsushi Adachi, Yasuyo Chochi, Atsunori Oga, Shigeto Kawauchi, Kimio Ishiglo, Kohsuke Sasaki
Pages: 1491-1496
Published online on: 01 June 2006

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Article

Expression of thymidine phosphorylase and VEGF in esophageal squamous cell carcinoma

Takuma Nomiya, Kenji Nemoto, Eiko Nakata, Yoshihiro Takai, Shogo Yamada
Pages: 1497-1501
Published online on: 01 June 2006

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Article

A useful protocol for analyses of mutations of the epidermal growth factor receptor gene

Dage Liu, Jun Nakano, Masaki Ueno, Daiki Masuya, Takashi Nakashima, Hiroyasu Yokomise, Kouichi Yube, Cheng-Long Huang
Pages: 1503-1505
Published online on: 01 June 2006

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Article

GEP associates with wild-type p53 in hepatocellular carcinoma

Siu Tim Cheung, San Yu Wong, Yuk Ting Lee, Sheung Tat Fan
Pages: 1507-1511
Published online on: 01 June 2006

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Article

Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients

R. Kumar, D. Kamdar, L. Madden, C. Hills, D. Crooks, D. O'Brien, J. Greenman
Pages: 1513-1516
Published online on: 01 June 2006

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Article

Antitumor effect of combination of S-1 and docetaxel on the human breast cancer xenograft transplanted into SCID mice

Akihiko Suto, Tetsuro Kubota, Masakazu Fukushima, Tadashi Ikeda, Toshio Takeshita, Harumi Ohmiya, Masaki Kitajima
Pages: 1517-1522
Published online on: 01 June 2006

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Article

G-CSF and/or M-CSF accelerate differentiation of bone marrow cells into endothelial progenitor cells in vitro

Yuming Zhang, Yasushi Adachi, Masayoshi Iwasaki, Keizo Minamino, Yasuhiro Suzuki, Keiji Nakano, Yasushi Koike, Hiromi Mukaide, Akio Shigematsu, Naoko Kiriyama, Chunfu Li, Susumu Ikehara
Pages: 1523-1527
Published online on: 01 June 2006

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Article

Expression of the TRAG-3 gene in human esophageal cancer: The frequent synchronous expression of MAGE-3 gene

Mitsuhiko Ohta, Fumiaki Tanaka, Noriaki Sadanaga, Hiroshi Yamaguchi, Hiroshi Inoue, Masaki Mori
Pages: 1529-1532
Published online on: 01 June 2006

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Article

In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer

Masaya Takizawa, Kazuyuki Kawakami, Tohru Obata, Isao Matsumoto, Yasuhiko Ohta, Makoto Oda, Takuma Sasaki, Go Watanabe
Pages: 1533-1539
Published online on: 01 June 2006

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Article

Interferon-α resistance can be reversed by inhibition of IFN-α-induced COX-2 expression potentially via STAT1 activation in A549 cells

Jeeyun Lee, Hae Hyun Jung, Young-Hyuck Im, Joo Hyun Kim, Joon Oh Park, Kihyun Kim, Won Seog Kim, Jin Seok Ahn, Chul Won Jung, Young Suk Park, Won Ki Kang, Keunchil Park
Pages: 1541-1549
Published online on: 01 June 2006

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Article

Expression of ACP6 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma

Takuya Ando, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Hiroki Kurehara, Nobuyoshi Sugito, Keisuke Tomoda, Ryota Mori, Nobuhiro Takashima, Ryo Ogawa, Yoshitaka Fujii
Pages: 1551-1555
Published online on: 01 June 2006

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Article

Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1

Moon-Kyoung Bae, Se-Hee Kim, Joo-Won Jeong, You Mie Lee, Hae-Sun Kim, Su-Ryun Kim, Il Yun, Soo-Kyung Bae, Kyu-Won Kim
Pages: 1557-1562
Published online on: 01 June 2006

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Article

G3139 induces cell death by caspase-dependent and -independent apoptosis on human melanoma cell lines

Shinnosuke Nakamura, Madoka Inui, Takahiko Kamei, Minoru Nakase, Kenya Okumura, Toshiro Tagawa
Pages: 1563-1568
Published online on: 01 June 2006

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Article

Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patients

Nobuyuki Genkai, Jumpei Homma, Masakazu Sano, Ryuichi Tanaka, Ryuya Yamanaka
Pages: 1569-1574
Published online on: 01 June 2006

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Article

Structure-activity studies with cytotoxic anthrapyrazoles

Asher Begleiter, Denny Lin, Kimberly K. Larson, Jennifer Lang, Xing Wu, Teresa Cabral, Hallie Taylor, Lynn J. Guziec, Paul D. Kerr, Brian B. Hasinoff, Frank S. Guziec Jr
Pages: 1575-1580
Published online on: 01 June 2006

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Article

Zanthoxyli Fructus induces growth arrest and apoptosis of LNCaP human prostate cancer cells in vitro and in vivo in association with blockade of the AKT and AR signal pathways

Yang Yang, Takayuki Ikezoe, Tamotsu Takeuchi, Yoshihiro Adachi, Yuji Ohtsuki, H. Phillip Koeffler, Hirokuni Taguchi
Pages: 1581-1590
Published online on: 01 June 2006

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Article

p16, MGMT, RARβ2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions

Mark J. Roth, Christian C. Abnet, Nan Hu, Quan-Hong Wang, Weng-Qiang Wei, Lisa Green, Mary D'Alelio, You-Lin Qiao, Sanford M. Dawsey, Philip R. Taylor, Karen Woodson
Pages: 1591-1597
Published online on: 01 June 2006

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Article

Functional analyses of C13orf19/P38IP in prostate cell lines

Doreen Kunze, Susanne Fuessel, Axel Meye, Manfred P. Wirth, Uta Schmidt
Pages: 1599-1604
Published online on: 01 June 2006

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Article

PD98059-inhibited invasion of Dunning rat prostate cancer cells involves suppression of motility but not MMP-2 or uPA secretion

Tuangporn Suthiphongchai, Suchada Phimsen, Usawadee Sakulkhu, Rutaiwan Tohtong
Pages: 1605-1610
Published online on: 01 June 2006

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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