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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2010 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Nutrition in oncology: the case of micronutrients (Review)

Alexander Ströhle, Kurt Zänker, Andreas Hahn
Pages: 815-828
Published online on: 01 October 2010

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Article Open Access

Pathotropic targeting advances clinical oncology: Tumor-targeted localization of therapeutic gene delivery

Frederick L. Hall, John P. Levy, Rebecca A. Reed, Wasinee N. Petchpud, Victoria S. Chua, Sant P. Chawla, Erlinda M. Gordon
Pages: 829-833
Published online on: 01 October 2010

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Article

Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase

Masakazu Fukushima, Kazuki Sakamoto, Hideyuki Ohshimo, Fumio Nakagawa, Tetsuo Taguchi
Pages: 835-842
Published online on: 01 October 2010

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Article Open Access

Anti-tumor effect by inhibition of NF-κB activation using nafamostat mesilate for pancreatic cancer in a mouse model

Kenei Furukawa, Tomonori Iida, Hiroaki Shiba, Yuki Fujiwara, Tadashi Uwagawa, Yohta Shimada, Takeyuki Misawa, Toya Ohashi, Katsuhiko Yanaga
Pages: 843-850
Published online on: 01 October 2010

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Article

p53 mutation, but not in vitro predictor genes of therapeutic efficacy of cisplatin, is clinically relevant in comparing partial and complete responder cases of maxillary squamous cell carcinoma

Itsuhiro Kudo, Mariko Esumi, Akihiro Kida, Minoru Ikeda
Pages: 851-856
Published online on: 01 October 2010

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Article

A new approach to concordance in mid-infrared spectromicroscopy mapping of malignant tumors

Kaiser Ali, Todd Reichert, Daniel Gomez, Yanjie Lu, Alexander Jan, Colleen Christensen
Pages: 857-860
Published online on: 01 October 2010

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Article

CD98 expression is associated with the grade of malignancy in thymic epithelial tumors

Kyoichi Kaira, Toshiaki Takahashi, Masato Abe, Hiroaki Akamatsu, Kazuo Nakagawa, Yasuhisa Ohde, Takehiro Okumura, Haruyasu Murakami, Asuka Tsuya, Yukiko Nakamura, Tateaki Naito, Haruhiko Kondo, Takashi Nakajima, Masahiro Endo, Nobuyuki Yamamoto
Pages: 861-867
Published online on: 01 October 2010

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Article

Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice

Yoshio Araki, Ken-Ichi Mukaisyo, Hiroyuki Sugihara, Yoshihide Fujiyama, Takanori Hattori
Pages: 869-874
Published online on: 01 October 2010

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Article

DNA copy number aberrations associated with aneuploidy and chromosomal instability in breast cancers

Shigeto Kawauchi, Tomoko Furuya, Kenzo Ikemoto, Motonao Nakao, Shigeru Yamamoto, Masaaki Oka, Kohsuke Sasaki
Pages: 875-883
Published online on: 01 October 2010

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Article

Genetic profiles distinguish different types of hereditary ovarian cancer

Katarina Domanska, Susanne Malander, Johan Staaf, Anna Karlsson, Åke Borg, Göran Jönsson, Mef Nilbert
Pages: 885-895
Published online on: 01 October 2010

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Article

High-level transgene expression mediated by the piggyBac transposon enhances transgenic therapeutic effects in cervical cancer xenografts

Yu Kang, Wenbo Yu, Qinwen Sun, Xiaoyan Zhang, Wei Jiang, Chaoqun Wu, Chunmei Chen, Jianren Gu, Yufang Zheng, Congjian Xu
Pages: 897-907
Published online on: 01 October 2010

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Article

Elevated L1CAM expression in precursor lesions and primary and metastastic tissues of pancreatic ductal adenocarcinoma

Frank Bergmann, Frauke Wandschneider, Bence Sipos, Gerhard Moldenhauer, Bodo Schniewind, Thilo Welsch, Peter Schirrmacher, Günter Klöppel, Peter Altevogt, Heiner Schäfer, Susanne Sebens Müerköster
Pages: 909-915
Published online on: 01 October 2010

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Article

High-throughput DNA hypermethylation profiling in different ovarian epithelial cancer subtypes using universal bead array

Man Soo Yoon, Dong Soo Suh, Kyung Un Choi, Mee Young Sol, Dong Hoon Shin, Won Young Park, Jung Hee Lee, Seong Muk Jeong, Woo Gyeong Kim, Na Ri Shin
Pages: 917-925
Published online on: 01 October 2010

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Article

Microsatellite instability and hMLH1 and hMSH2 expression in renal tumors

Giuseppe Altavilla, Matteo Fassan, Graziella Busatto, Martina Orsolan, Luciano Giacomelli
Pages: 927-932
Published online on: 01 October 2010

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Article

C4orf7 contributes to ovarian cancer metastasis by promoting cancer cell migration and invasion

Changyu Wang, Li Zhou, Shuang Li, Juncheng Wei, Wei Wang, Ting Zhou, Shujie Liao, Danhui Weng, Dongrui Deng, Yanjie Weng, Shixuan Wang, Ding Ma
Pages: 933-939
Published online on: 01 October 2010

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Article

The antitumor and antimetastatic effects of N-trimethyl chitosan-encapsulated camptothecin on ovarian cancer with minimal side effects

Lina Zhou, Licheng Du, Xiancheng Chen, Xingyi Li, Zhiyong Li, Yuan Wen, Zhengyu Li, Xiang He, Yuquan Wei, Xia Zhao, Zhiyong Qian
Pages: 941-948
Published online on: 01 October 2010

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Article

14-3-3σ expression as a prognostic marker in undifferentiated nasopharyngeal carcinoma

Sylvia Yat-Yee Chan, Ka-Fai To, Sing-Fai Leung, William Wai-Lun Yip, Michael Ko-Fung Mak, Grace Tin-Yun Chung, Kwok-Wai Lo
Pages: 949-955
Published online on: 01 October 2010

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Article

Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer

Hyunseung Lee, Ju-Hee Lee, Kyung Hee Jung, Soon-Sun Hong
Pages: 957-963
Published online on: 01 October 2010

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Article

Role for ezrin in breast cancer cell chemotaxis to CCL5

Juanjuan Li, Yi Tu, Jing Wen, Feng Yao, Wen Wei, Shengrong Sun
Pages: 965-971
Published online on: 01 October 2010

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Article

Thermoseed hyperthermia treatment of mammary orthotopic transplantation tumors in rats and impact on immune function

Weiwei Ouyang, Fuping Gao, Lufang Wang, Xiaoxue Xie, Fenglin Lei, Jumei Zhou, Yuping Liao, Meizuo Zhong, Jintian Tang
Pages: 973-979
Published online on: 01 October 2010

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Article

SATB1 is an independent prognostic marker for gastric cancer in a Chinese population

Xiaoming Lu, Chao Cheng, Shikai Zhu, Yun Yang, Liduan Zheng, Guobin Wang, Xiaogang Shu, Ke Wu, Ke Liu, Qiang Tong
Pages: 981-987
Published online on: 01 October 2010

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Article

The chemokine receptor 7 regulates cell adhesion and migration via β1 integrin in metastatic squamous cell carcinoma of the head and neck

Peng Li, Zhen-Jin Zhao, Fa-Yu Liu, Li-Yan Sun, Xue Ding, Wen-Zhong Zhang, De-Hao Shang, Chang-Fu Sun
Pages: 989-995
Published online on: 01 October 2010

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Article

A pivotal role for Pim-1 kinase in esophageal squamous cell carcinoma involving cell apoptosis induced by reducing Akt phosphorylation

Shenglei Li, Yu Xi, Hongyan Zhang, Yange Wang, Xin Wang, Hongtao Liu, Kuisheng Chen
Pages: 997-1004
Published online on: 01 October 2010

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Article

RhoA protein is generally distributed in the nuclei of cancer cells

Yueying Li, Yongchang Chen, Yan Tao, Jin Xu, Miao Chen
Pages: 1005-1009
Published online on: 01 October 2010

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Article Open Access

Acquired resistance to miriplatin in rat hepatoma AH109A/MP10 is associated with increased Bcl-2 expression, leading to defects in inducing apoptosis

Mitsuharu Hanada, Hideo Takasu, Makoto Kitaura
Pages: 1011-1018
Published online on: 01 October 2010

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Article

VEGFR and EGFR inhibition increases epithelial cellular characteristics and chemotherapy sensitivity in mesenchymal bladder cancer cells

Yuan Li, Xiaoping Yang, Lih-Jen Su, Thomas W. Flaig
Pages: 1019-1028
Published online on: 01 October 2010

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Article

Possibility of paclitaxel as an alternative radiosensitizer to 5-fluorouracil for colon cancer

Junichiro Hiro, Yasuhiro Inoue, Yuji Toiyama, Shigeyuki Yoshiyama, Koji Tanaka, Yasuhiko Mohri, Chikao Miki, Masato Kusunoki
Pages: 1029-1034
Published online on: 01 October 2010

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Article

WNT pathway in oral cancer: Epigenetic inactivation of WNT-inhibitors

G. Pannone, P. Bufo, A. Santoro, R. Franco, G. Aquino, F. Longo, G. Botti, R. Serpico, B. Cafarelli, A. Abbruzzese, M. Caraglia, S. Papagerakis, L. Lo Muzio
Pages: 1035-1041
Published online on: 01 October 2010

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Article

Up-regulation of NKG2F receptor, a functionally unknown killer receptor, of human natural killer cells by interleukin-2 and interleukin-15

Haihua Huang, Xin Wang, Yukun Zhang, Xiaodong Zheng, Haiming Wei, Rui Sun
Pages: 1043-1048
Published online on: 01 October 2010

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Article

Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy

Alexandra Murray, Samantha J. Little, Paul Stanley, Anthony Maraveyas, Lynn Cawkwell
Pages: 1049-1058
Published online on: 01 October 2010

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Article

Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors Retraction in /10.3892/or.2026.9101

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Pages: 1059-1065
Published online on: 01 October 2010

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Article

Establishment of a rhabdomyosarcoma xenograft model in human-adapted mice

Guido Seitz, Matthias Pfeiffer, Jörg Fuchs, Steven W. Warmann, Ivo Leuschner, Christian Vokuhl, Peter Lang, Rupert Handgretinger, Sorin Armeanu-Ebinger
Pages: 1067-1072
Published online on: 01 October 2010

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Article

Association between metalloproteinases 2 and 9 activity and ERK1/2 phosphorylation status in head and neck cancers: An ex vivo study

Werner Garavello, Daniele Maggioni, Gabriella Nicolini, Lorenzo Motta, Giovanni Tredici, Renato Gaini
Pages: 1073-1078
Published online on: 01 October 2010

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Article

The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk

Bruno Costa Gomes, Susana Nunes Silva, Ana Paula Azevedo, Isabel Manita, Octávia Monteiro Gil, Teresa Cruz Ferreira, Edward Limbert, José Rueff, Jorge Francisco Gaspar
Pages: 1079-1085
Published online on: 01 October 2010

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Article

Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro

Zhaoli Dai, Vidhya Nair, Maruf Khan, Henry P. Ciolino
Pages: 1087-1091
Published online on: 01 October 2010

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Article

β-catenin siRNA regulation of apoptosis- and angiogenesis-related gene expression in hepatocellular carcinoma cells: potential uses for gene therapy

Xin-Hong Wang, Xun Sun, Xiang-Wei Meng, Zhi-Wu Lv, Ya-Ju Du, Yan Zhu, Jing Chen, De-Xia Kong, Shi-Zhu Jin
Pages: 1093-1099
Published online on: 01 October 2010

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Article

Predictive significance of the cut-off value of CD20 expression in patients with B-cell lymphoma

Mateja Horvat, Veronika Kloboves Prevodnik, Jaka Lavrencak, Barbara Jezersek Novakovic
Pages: 1101-1107
Published online on: 01 October 2010

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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