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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2004 Volume 14 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Regularity of distribution of immunoreactive pulmonary surfactant protein A in rat tissues

J. M. Luo, Y. S. Wan, Z. Q. Liu, G. R. Wang, J. Floros, H. H. Zhou
Pages: 343-351
Published online on: 01 September 2004

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Article

Native LDL and Oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-κB, CRE dependent pathway and affect PGE2 synthesis

G. D. Norata, A. Pirillo, F. Pellegatta, H. Inoue, A. L. Catapano
Pages: 353-359
Published online on: 01 September 2004

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Article

Structural organization of the mouse neurochondrin gene

Reiko Mochizuki-Sakisaka, Minori Dateki, Yasuyuki Ishizuka, Kazuyuki Yanai, Yoichi Matsuda, Yoshihiko Koga, Akiyoshi Fukamizu
Pages: 361-366
Published online on: 01 September 2004

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Article

New experimental models for the in vitro reconstitution of human bladder mucosa

Sergio De Angeli, Laura Del Pup, Andrea Fandella, Rosa Di Liddo, Giuseppe Anselmo, Carlo Macchi, Maria Teresa Conconi, Pier Paolo Parnigotto, Gastone G. Nussdorfer
Pages: 367-372
Published online on: 01 September 2004

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Article

Imatinib mesylate (STI571) interference with growth of neuroectodermal tumour cell lines does not critically involve c-Kit inhibition

Geertuy Te Kronnie, Fabio Timeus, Andrea Rinaldi, Nicoletta Crescenzio, Monica Spinelli, Angelo Rosolen, Emanuela Ricotti, Giuseppe Basso
Pages: 373-382
Published online on: 01 September 2004

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Article

Generation and characterization of dimeric small immunoproteins specific for neuroblastoma associated antigen GD2

Marzia Occhino, Lizzia Raffaghello, Oscar Burrone, Claudio Gambini, Vito Pistoia, Maria Valeria Corrias, Marco Bestagno
Pages: 383-388
Published online on: 01 September 2004

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Article

The expression of vascular endothelial growth factor-A and -C, and receptors 1 and 3: Correlation with lymph node metastasis and prognosis in tongue squamous cell carcinoma

Yuji Tanigaki, Yoji Nagashima, Yoshiaki Kitamura, Hideki Matsuda, Yasukazu Mikami, Mamoru Tsukuda
Pages: 389-395
Published online on: 01 September 2004

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Article

Immunocytochemical characteristics of human osteosarcoma cell line HS-Os-1: Possible implication in apoptotic resistance against irradiation

Yasuhiro Ogawa, Toshiaki Takahashi, Toshihiro Kobayashi, Shinji Kariya, Akihito Nishioka, Shinji Hamasato, Toshiaki Moriki, Harumichi Seguchi, Shoji Yoshida, Hiroshi Sonobe
Pages: 397-403
Published online on: 01 September 2004

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Article

A combination of selective COX-2 inhibitors and hydrogen peroxide increase the reactive oxygen species formation in osteosarcoma cells after X-ray irradiation

Toshiaki Takahashi, Yasuhiro Ogawa, Toshihiro Kobayashi, Hiroshi Sonobe, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshida
Pages: 405-408
Published online on: 01 September 2004

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Article

Transcriptional gene expression profile of human nasopharynx

Xiao-Qiong Liu, Yan Zhou, Lin-Jie Zhang, Hao Xu, Han-Kui Chen, Zhi-Gang Pan, Yi-Xin Zeng
Pages: 409-420
Published online on: 01 September 2004

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Article

Possible association of interleukin 1B C-31T polymorphism among Helicobacter pylori seropositive Japanese Brazilians with susceptibility to atrophic gastritis

Miyuki Uno, Lucy S. Ito, Sueli M. Oba-Shinjo, Suely K.N. Marie, Samuel K. Shinjo, Nobuyuki Hamajima
Pages: 421-426
Published online on: 01 September 2004

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Characterization of protein tyrosine phosphatase activity in rat liver microsomes: Suppressive effect of endogenous regucalcin in transgenic rats

Yuko Fukaya, Masayoshi Yamaguchi
Pages: 427-432
Published online on: 01 September 2004

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Article

Blood antioxidant parameters in patients with diabetic retinopathy

Krzysztof Siemianowicz, Jan Gminski, Alicja Telega, Aneta Wójcik, Barbara Posielezna, Rozalia Grabowska-Bochenek, Tomasz Francuz
Pages: 433-437
Published online on: 01 September 2004

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Article

Relatively common mutations of the Bloom syndrome gene in the Japanese population

Hideo Kaneko, Kouji Isogai, Toshiyuki Fukao, Eiko Matsui, Kimiko Kasahara, Akihiro Yachie, Hidetoshi Seki, Shoichi Koizumi, Masami Arai, Joji Utunomiya, Yoshio Miki, Naomi Kondo
Pages: 439-442
Published online on: 01 September 2004

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Review

Nitric oxide as a possible mechanism for understanding the therapeutic effects of osteopathic manipulative medicine (Review)

Elliott Salamon, Wei Zhu, George B. Stefano
Pages: 443-449
Published online on: 01 September 2004

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Article

Bone loss in regucalcin transgenic rats: Enhancement of osteoclastic cell formation from bone marrow of rats with increasing age

Satoshi Uchiyama, Masayoshi Yamaguchi
Pages: 451-455
Published online on: 01 September 2004

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Article

Beacon[47-73] inhibits glucocorticoid secretion and growth of cultured rat and human adrenocortical cells

Agnieszka Ziolkowska, Gianni Carraro, Piera Rebuffat, Raffaella Spinazzi, Gastone G. Nussdorfer, Marcin Rucinski, Ludwik K. Malendowicz
Pages: 457-461
Published online on: 01 September 2004

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Article

Germ-line mutation of Foxn5 gene in mouse lineage

Masuko Katoh, Masaru Katoh
Pages: 463-467
Published online on: 01 September 2004

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Article

Characterization of FMN2 gene at human chromosome 1q43

Masuko Katoh, Masaru Katoh
Pages: 469-474
Published online on: 01 September 2004

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Article

Evaluation of Fas gene promoter polymorphism in cervical cancer patients

Aleksandra Dybikowska, Wojciech Sliwinski, Janusz Emerich, Anna J. Podhajska
Pages: 475-478
Published online on: 01 September 2004

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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Review Open Access

High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Review

Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Review Open Access

Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Review Open Access

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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Review Open Access

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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Correction Open Access

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Review Open Access

Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Review Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Review Open Access

Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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