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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2013 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1

Ruth Amann, Beat Trueb
Pages: 983-988
Published online on: 10 September 2013

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Article

Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients: A double-blind placebo-controlled study

Ryuichiro Sakata, Toru Nakamura, Takuji Torimura, Takato Ueno, Michio Sata
Pages: 989-994
Published online on: 20 September 2013

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Article

Diffusion tensor and volumetric magnetic resonance imaging using an MR-compatible hand-induced robotic device suggests training-induced neuroplasticity in patients with chronic stroke

Asimina Lazaridou, Loukas Astrakas, Dionyssios Mintzopoulos, Azadeh Khanicheh, Aneesh B. Singhal, Michael A. Moskowitz, Bruce Rosen, Aria A. Tzika
Pages: 995-1000
Published online on: 27 August 2013

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Article

Duhuo Jisheng Decoction promotes chondrocyte proliferation through accelerated G1/S transition in osteoarthritis

Guangwen Wu, Wenlie Chen, Huailing Fan, Chunsong Zheng, Jianfeng Chu, Ruhui Lin, Jinxia Ye, Huifeng Xu, Xihai Li, Yunmei  Huang, Hongzhi Ye, Xianxiang Liu, Mingxia Wu
Pages: 1001-1010
Published online on: 04 September 2013

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Article

Cardioprotective effects of exenatide against oxidative stress-induced injury

Guanglei Chang, Dongying Zhang, Hui Yu, Peng Zhang, Ying Wang, Aihua Zheng, Shu Qin
Pages: 1011-1020
Published online on: 27 August 2013

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Article

Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS

Fang Xie, Jiu-Cong Zhang, Han Fu, Jun Chen
Pages: 1021-1028
Published online on: 11 September 2013

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Article

The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosis through inhibition of de novo lipogenesis in high-fructose-fed rats

Lu-Ping Ren, Guang-Yao Song, Zhi-Juan Hu, Mingming Zhang, Lanbo Peng, Shu-Chun Chen, Limin Wei, Fan Li, Wen Sun
Pages: 1029-1036
Published online on: 12 September 2013

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Article

Selective inhibition of PKCβ2 preserves cardiac function after myocardial infarction and is associated with improved angiogenesis of ischemic myocardium in diabetic rats

Fabin Wang, Dong Huang, Wei Zhu, Shuai Li, Meiling Yan, Meng Wei, Jingbo Li
Pages: 1037-1046
Published online on: 28 August 2013

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Article

A new method for the quantification of aortic calcification by three-dimensional micro-computed tomography

C. Huesa, J. L. Millán, R. J. van 't Hof, V. E. MacRae
Pages: 1047-1050
Published online on: 12 September 2013

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Article

Crosstalk between TLR5 and Notch1 signaling in epithelial cells during intestinal inflammation

Monowar Aziz, Shunji Ishihara, Mesbah Uddin Ansary, Hiroki Sonoyama, Yasumasa Tada, Akihiko Oka, Ryusaku Kusunoki, Yuji Tamagawa, Nobuhiko Fukuba, Yoshiyuki Mishima, Tsuyoshi Mishiro, Naoki Oshima, Ichiro Moriyama, Norihisa Ishimura, Shuichi Sato, Takafumi Yuki, Kousaku Kawashima, Yoshikazu Kinoshita
Pages: 1051-1062
Published online on: 18 September 2013

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Article

Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo

Shan Ren, Yongjun Liu, Jinfeng Ma, Yong Liu, Zezheng Diao, Deling Yang, Xu Zhang, Yongming Xi, Yougu Hu
Pages: 1063-1068
Published online on: 17 September 2013

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Article

Tongue coating microbiome regulates the changes in tongue texture and coating in patients with post-menopausal osteoporosis of Gan-shen deficiency syndrome type

Wenna Liang, Xihai Li, Yachan Li, Candong Li, Bizheng Gao, Huijuan Gan, Sumin Li, Jianying Shen, Jie Kang, Shanshan Ding, Xuejuan Lin, Linghong Liao
Pages: 1069-1076
Published online on: 10 September 2013

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Article

Saponin B, a novel cytostatic compound purified from Anemone taipaiensis, induces apoptosis in a human glioblastoma cell line

Yuangang Wang, Haifeng Tang, Yun Zhang, Juan Li, Bo Li, Zhenhui Gao, Xiaoyang Wang, Guang Cheng, Zhou Fei
Pages: 1077-1084
Published online on: 18 September 2013

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Article

Effects of diagnostic ultrasound on HSP70 expression in chorionic villi in rats during early pregnancy and the role of HSP70 in apoptosis in chorionic villi

Haitao Liu, Feng Hou, Haiying Liang, Guocheng Liu, Yunfei Li
Pages: 1085-1092
Published online on: 12 September 2013

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Article

High interstitial fluid pressure promotes tumor cell proliferation and invasion in oral squamous cell carcinoma

Tao Yu, Kun Liu, Yingying Wu, Jinchuan Fan, Jianchao Chen, Chao Li, Guiquan Zhu, Zhaohui Wang, Longjiang Li
Pages: 1093-1100
Published online on: 13 September 2013

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Article

Troglitazone upregulates PTEN expression and induces the apoptosis of pulmonary artery smooth muscle cells under hypoxic conditions

Wei-Feng Pi, Xue-Jun Guo, Li-Ping Su, Wei-Guo Xu
Pages: 1101-1109
Published online on: 11 September 2013

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Article

Establishment of a transgenic mouse model of corneal dystrophy overexpressing human BIGH3

Xin Liao, Hongping Cui, Fang Wang
Pages: 1110-1114
Published online on: 04 September 2013

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Article

Analysis of microRNA expression profile by small RNA sequencing in Down syndrome fetuses

Yong Xu, Wuxian Li, Xueyan Liu, Hualin Ma, Zhiguang Tu, Yong Dai
Pages: 1115-1125
Published online on: 18 September 2013

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Article

Human group V secretory phospholipase A2 is associated with lipid rafts and internalized in a flotillin‑dependent pathway

Hae Jin Rhee, Liting Ji, Seung‑Hyuk Kim, Jongho Lee
Pages: 1126-1136
Published online on: 12 September 2013

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Article

The O‑glycosylation mutant osteopontin alters lung cancer cell growth and migration in vitro and in vivo

Arash Minai‑Tehrani, Seung‑Hee Chang, Seung Bum Park, Myung‑Haing Cho
Pages: 1137-1149
Published online on: 05 September 2013

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Article

High-glucose-based peritoneal dialysis solution induces the upregulation of VEGF expression in human peritoneal mesothelial cells: The role of pleiotrophin

Jia Liu, Xia Wu, Yanchun Liu, Yaguang Xu, Yuhan Huang, Changying Xing, Xiaoyun Wang
Pages: 1150-1158
Published online on: 12 September 2013

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Article

Aquaporin-9 downregulation prevents steatosis in oleic acid-induced non-alcoholic fatty liver disease cell models

Chuan Wang, Zi-Lan Lv, Yu-Jun Kang, Ting-Xiu Xiang, Pi-Long Wang, Zheng Jiang
Pages: 1159-1165
Published online on: 19 September 2013

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Article

Novel mutation in exon 56 of the dystrophin gene in a child with Duchenne muscular dystrophy

Jian-Fang Zhu, Hui-Hui Liu, Tao Zhou, Li Tian
Pages: 1166-1170
Published online on: 18 September 2013

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Article

Purpurogallin exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated BV2 microglial cells through the inactivation of the NF‑κB and MAPK signaling pathways

Hye Young Park, Tae Hoon Kim, Chan Gil Kim, Gi‑Young Kim, Cheol Min Kim, Nam Deuk Kim, Byung Woo Kim, Hye Jin Hwang, Yung Hyun Choi
Pages: 1171-1178
Published online on: 30 August 2013

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Article

α-lipoic acid attenuates obesity-associated hippocampal neuroinflammation and increases the levels of brain-derived neurotrophic factor in ovariectomized rats fed a high-fat diet

Yulian Miao, Jianmin Ren, Ling Jiang, Jinbo Liu, Bei Jiang, Xiaoli Zhang
Pages: 1179-1186
Published online on: 05 September 2013

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Article

Novel function of the poly(c)-binding protein α-CP2 as a transcriptional activator that binds to single-stranded DNA sequences

Duk-Hee Kang, Kyu Young Song, Li-Na Wei, Ping-Yee Law, Horace H. Loh, Hack Sun Choi
Pages: 1187-1194
Published online on: 11 September 2013

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Article

Association between CAG repeat polymorphisms and the risk of prostate cancer: A meta-analysis by race, study design and the number of (CAG)n repeat polymorphisms

Jun-Hyun Sun, Sang-Ah Lee
Pages: 1195-1203
Published online on: 23 August 2013

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Article

Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis

Bo Gao, Wang Sun, Xianqi Wang, Xu Jia, Biao Ma, Yu Chang, Weihui Zhang, Dongbo Xue
Pages: 1204-1214
Published online on: 13 September 2013

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Article

Knockdown of mTOR by lentivirus‑mediated RNA interference suppresses atherosclerosis and stabilizes plaques via a decrease of macrophages by autophagy in apolipoprotein E‑deficient mice

Xiaochuang Wang, Lingxia Li, Manxiang Li, Xiaoyan Dang, Lin Wan, Ni Wang, Xiaoju Bi, Changwei Gu, Suijuan Qiu, Xiaolin Niu, Xinye Zhu, Lina Wang
Pages: 1215-1221
Published online on: 12 September 2013

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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