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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2013 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1

Ruth Amann, Beat Trueb
Pages: 983-988
Published online on: 10 September 2013

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Article

Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients: A double-blind placebo-controlled study

Ryuichiro Sakata, Toru Nakamura, Takuji Torimura, Takato Ueno, Michio Sata
Pages: 989-994
Published online on: 20 September 2013

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Article

Diffusion tensor and volumetric magnetic resonance imaging using an MR-compatible hand-induced robotic device suggests training-induced neuroplasticity in patients with chronic stroke

Asimina Lazaridou, Loukas Astrakas, Dionyssios Mintzopoulos, Azadeh Khanicheh, Aneesh B. Singhal, Michael A. Moskowitz, Bruce Rosen, Aria A. Tzika
Pages: 995-1000
Published online on: 27 August 2013

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Article

Duhuo Jisheng Decoction promotes chondrocyte proliferation through accelerated G1/S transition in osteoarthritis

Guangwen Wu, Wenlie Chen, Huailing Fan, Chunsong Zheng, Jianfeng Chu, Ruhui Lin, Jinxia Ye, Huifeng Xu, Xihai Li, Yunmei  Huang, Hongzhi Ye, Xianxiang Liu, Mingxia Wu
Pages: 1001-1010
Published online on: 04 September 2013

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Article

Cardioprotective effects of exenatide against oxidative stress-induced injury

Guanglei Chang, Dongying Zhang, Hui Yu, Peng Zhang, Ying Wang, Aihua Zheng, Shu Qin
Pages: 1011-1020
Published online on: 27 August 2013

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Article

Age-related decline of myelin proteins is highly correlated with activation of astrocytes and microglia in the rat CNS

Fang Xie, Jiu-Cong Zhang, Han Fu, Jun Chen
Pages: 1021-1028
Published online on: 11 September 2013

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Article

The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosis through inhibition of de novo lipogenesis in high-fructose-fed rats

Lu-Ping Ren, Guang-Yao Song, Zhi-Juan Hu, Mingming Zhang, Lanbo Peng, Shu-Chun Chen, Limin Wei, Fan Li, Wen Sun
Pages: 1029-1036
Published online on: 12 September 2013

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Article

Selective inhibition of PKCβ2 preserves cardiac function after myocardial infarction and is associated with improved angiogenesis of ischemic myocardium in diabetic rats

Fabin Wang, Dong Huang, Wei Zhu, Shuai Li, Meiling Yan, Meng Wei, Jingbo Li
Pages: 1037-1046
Published online on: 28 August 2013

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Article

A new method for the quantification of aortic calcification by three-dimensional micro-computed tomography

C. Huesa, J. L. Millán, R. J. van 't Hof, V. E. MacRae
Pages: 1047-1050
Published online on: 12 September 2013

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Article

Crosstalk between TLR5 and Notch1 signaling in epithelial cells during intestinal inflammation

Monowar Aziz, Shunji Ishihara, Mesbah Uddin Ansary, Hiroki Sonoyama, Yasumasa Tada, Akihiko Oka, Ryusaku Kusunoki, Yuji Tamagawa, Nobuhiko Fukuba, Yoshiyuki Mishima, Tsuyoshi Mishiro, Naoki Oshima, Ichiro Moriyama, Norihisa Ishimura, Shuichi Sato, Takafumi Yuki, Kousaku Kawashima, Yoshikazu Kinoshita
Pages: 1051-1062
Published online on: 18 September 2013

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Article

Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo

Shan Ren, Yongjun Liu, Jinfeng Ma, Yong Liu, Zezheng Diao, Deling Yang, Xu Zhang, Yongming Xi, Yougu Hu
Pages: 1063-1068
Published online on: 17 September 2013

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Article

Tongue coating microbiome regulates the changes in tongue texture and coating in patients with post-menopausal osteoporosis of Gan-shen deficiency syndrome type

Wenna Liang, Xihai Li, Yachan Li, Candong Li, Bizheng Gao, Huijuan Gan, Sumin Li, Jianying Shen, Jie Kang, Shanshan Ding, Xuejuan Lin, Linghong Liao
Pages: 1069-1076
Published online on: 10 September 2013

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Article

Saponin B, a novel cytostatic compound purified from Anemone taipaiensis, induces apoptosis in a human glioblastoma cell line

Yuangang Wang, Haifeng Tang, Yun Zhang, Juan Li, Bo Li, Zhenhui Gao, Xiaoyang Wang, Guang Cheng, Zhou Fei
Pages: 1077-1084
Published online on: 18 September 2013

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Article

Effects of diagnostic ultrasound on HSP70 expression in chorionic villi in rats during early pregnancy and the role of HSP70 in apoptosis in chorionic villi

Haitao Liu, Feng Hou, Haiying Liang, Guocheng Liu, Yunfei Li
Pages: 1085-1092
Published online on: 12 September 2013

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Article

High interstitial fluid pressure promotes tumor cell proliferation and invasion in oral squamous cell carcinoma

Tao Yu, Kun Liu, Yingying Wu, Jinchuan Fan, Jianchao Chen, Chao Li, Guiquan Zhu, Zhaohui Wang, Longjiang Li
Pages: 1093-1100
Published online on: 13 September 2013

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Article

Troglitazone upregulates PTEN expression and induces the apoptosis of pulmonary artery smooth muscle cells under hypoxic conditions

Wei-Feng Pi, Xue-Jun Guo, Li-Ping Su, Wei-Guo Xu
Pages: 1101-1109
Published online on: 11 September 2013

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Article

Establishment of a transgenic mouse model of corneal dystrophy overexpressing human BIGH3

Xin Liao, Hongping Cui, Fang Wang
Pages: 1110-1114
Published online on: 04 September 2013

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Article

Analysis of microRNA expression profile by small RNA sequencing in Down syndrome fetuses

Yong Xu, Wuxian Li, Xueyan Liu, Hualin Ma, Zhiguang Tu, Yong Dai
Pages: 1115-1125
Published online on: 18 September 2013

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Article

Human group V secretory phospholipase A2 is associated with lipid rafts and internalized in a flotillin‑dependent pathway

Hae Jin Rhee, Liting Ji, Seung‑Hyuk Kim, Jongho Lee
Pages: 1126-1136
Published online on: 12 September 2013

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Article

The O‑glycosylation mutant osteopontin alters lung cancer cell growth and migration in vitro and in vivo

Arash Minai‑Tehrani, Seung‑Hee Chang, Seung Bum Park, Myung‑Haing Cho
Pages: 1137-1149
Published online on: 05 September 2013

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Article

High-glucose-based peritoneal dialysis solution induces the upregulation of VEGF expression in human peritoneal mesothelial cells: The role of pleiotrophin

Jia Liu, Xia Wu, Yanchun Liu, Yaguang Xu, Yuhan Huang, Changying Xing, Xiaoyun Wang
Pages: 1150-1158
Published online on: 12 September 2013

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Article

Aquaporin-9 downregulation prevents steatosis in oleic acid-induced non-alcoholic fatty liver disease cell models

Chuan Wang, Zi-Lan Lv, Yu-Jun Kang, Ting-Xiu Xiang, Pi-Long Wang, Zheng Jiang
Pages: 1159-1165
Published online on: 19 September 2013

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Article

Novel mutation in exon 56 of the dystrophin gene in a child with Duchenne muscular dystrophy

Jian-Fang Zhu, Hui-Hui Liu, Tao Zhou, Li Tian
Pages: 1166-1170
Published online on: 18 September 2013

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Article

Purpurogallin exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated BV2 microglial cells through the inactivation of the NF‑κB and MAPK signaling pathways

Hye Young Park, Tae Hoon Kim, Chan Gil Kim, Gi‑Young Kim, Cheol Min Kim, Nam Deuk Kim, Byung Woo Kim, Hye Jin Hwang, Yung Hyun Choi
Pages: 1171-1178
Published online on: 30 August 2013

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Article

α-lipoic acid attenuates obesity-associated hippocampal neuroinflammation and increases the levels of brain-derived neurotrophic factor in ovariectomized rats fed a high-fat diet

Yulian Miao, Jianmin Ren, Ling Jiang, Jinbo Liu, Bei Jiang, Xiaoli Zhang
Pages: 1179-1186
Published online on: 05 September 2013

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Article

Novel function of the poly(c)-binding protein α-CP2 as a transcriptional activator that binds to single-stranded DNA sequences

Duk-Hee Kang, Kyu Young Song, Li-Na Wei, Ping-Yee Law, Horace H. Loh, Hack Sun Choi
Pages: 1187-1194
Published online on: 11 September 2013

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Article

Association between CAG repeat polymorphisms and the risk of prostate cancer: A meta-analysis by race, study design and the number of (CAG)n repeat polymorphisms

Jun-Hyun Sun, Sang-Ah Lee
Pages: 1195-1203
Published online on: 23 August 2013

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Article

Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis

Bo Gao, Wang Sun, Xianqi Wang, Xu Jia, Biao Ma, Yu Chang, Weihui Zhang, Dongbo Xue
Pages: 1204-1214
Published online on: 13 September 2013

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Article

Knockdown of mTOR by lentivirus‑mediated RNA interference suppresses atherosclerosis and stabilizes plaques via a decrease of macrophages by autophagy in apolipoprotein E‑deficient mice

Xiaochuang Wang, Lingxia Li, Manxiang Li, Xiaoyan Dang, Lin Wan, Ni Wang, Xiaoju Bi, Changwei Gu, Suijuan Qiu, Xiaolin Niu, Xinye Zhu, Lina Wang
Pages: 1215-1221
Published online on: 12 September 2013

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Review Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Review Open Access

Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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