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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2015 Volume 36 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)

Julian Banerji
Pages: 607-626
Published online on: 15 July 2015

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Article Open Access

Autocrine motility factor receptor promotes the proliferation of human acute monocytic leukemia THP-1 cells

Yingchao Wang, Lina Ma, Chunmei Wang, Guangyao Sheng, Lei Feng, Chuyun Yin
Pages: 627-632
Published online on: 30 June 2015

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Article Open Access

Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice

Peng Zhao, Ru Zhou, Xiao-Yun Zhu, Yin-Ju Hao, Nan Li, Jie Wang, Yang Niu, Tao Sun, Yu-Xiang Li, Jian-Qiang Yu
Pages: 633-644
Published online on: 24 June 2015

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Article Open Access

Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors

Lei Zhao, Shizhou Liu, Xiaofang Che, Kezuo Hou, Yanju Ma, Ce Li, Ti Wen, Yibo Fan, Xuejun Hu, Yunpeng Liu, Xiujuan Qu
Pages: 645-652
Published online on: 30 June 2015

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Article Open Access

Numb downregulation suppresses cell growth and is associated with a poor prognosis of human hepatocellular carcinoma

Chengzhi Xie, Zhenhui Lu, Guoxing Liu, Yu Fang, Jiefeng Liu, Zhao Huang, Fusheng Wang, Xiaolong Wu, Xiaohua Lei, Xiaocheng Li, Yueming Zhang, Zecheng Hu, Ke Qian, Jixiong Hu, Shengfu Huang, Dewu Zhong, Xundi Xu
Pages: 653-660
Published online on: 09 July 2015

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Article Open Access

Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition

Kang Xu, Weijian Chen, Xiaofei Wang, Yan Peng, Anjing Liang, Dongsheng Huang, Chunhai Li, Wei Ye
Pages: 661-668
Published online on: 10 July 2015

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Article Open Access

miR-135 family members mediate podocyte injury through the activation of Wnt/β-catenin signaling

Xianggui Yang, Xiaoyan Wang, Fang Nie, Tianming Liu, Xuejing Yu, Honglian Wang, Qianyin Li, Rui Peng, Zhaomin Mao, Qin Zhou, Ge Li
Pages: 669-677
Published online on: 24 June 2015

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Article Open Access

Pathogenesis of glucocorticoid-induced avascular necrosis: A microarray analysis of gene expression in vitro

Yanyan Bian, Wenwei Qian, Hongling Li, Robert Chunhua Zhao, Wang Xing Shan, Xisheng Weng
Pages: 678-684
Published online on: 06 July 2015

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Article Open Access

Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway Retraction in /10.3892/ijmm.2023.5241

Zhi Zeng, Wen‑Dong Huang, Qi Gao, Mei‑Ling Su, Yong‑Fei Yang, Zhao‑Chun Liu, Bang‑Hao Zhu
Pages: 685-697
Published online on: 22 July 2015

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Article Open Access

5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma

Wenming Wang, Jing Wang, Min Li, Jianming Ying, Hongmei Jing
Pages: 698-704
Published online on: 01 July 2015

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Article Open Access

FGF-2 induces the proliferation of human periodontal ligament cells and modulates their osteoblastic phenotype by affecting Runx2 expression in the presence and absence of osteogenic inducers

Shaofeng An, Xiangya Huang, Yan Gao, Junqi Ling, Yihua Huang, Yin Xiao
Pages: 705-711
Published online on: 01 July 2015

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Article

Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats: Gene expression profiles in the kidneys

Yuko Watanabe, Momoko Yoshida, Kyosuke Yamanishi, Hideyuki Yamamoto, Daisuke Okuzaki, Hiroshi Nojima, Teruo Yasunaga, Haruki Okamura, Hisato Matsunaga, Hiromichi Yamanishi
Pages: 712-724
Published online on: 10 July 2015

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Article

Valproic acid-induced histone acetylation suppresses CYP19 gene expression and inhibits the growth and survival of endometrial stromal cells

Yu Chen, Shengyun Cai, Jingwen Wang, Mingjuan Xu
Pages: 725-732
Published online on: 29 June 2015

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Article

Apelin-13 induces MCF-7 cell proliferation and invasion via phosphorylation of ERK1/2

Xuewei Peng, Fengyu Li, Ping Wang, Shengnan Jia, Lili Sun, Hongliang Huo
Pages: 733-738
Published online on: 30 June 2015

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Article

Chronic ethanol treatment of human hepatocytes inhibits the activation of the insulin signaling pathway by increasing cytosolic free calcium levels

Yi‑Min Chen, Jin‑Fang Zhao, Yong‑Lin Liu, Jie Chen, Rong‑Lin Jiang
Pages: 739-746
Published online on: 13 July 2015

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Article

Identification of novel targets for the diagnosis and treatment of liver fibrosis

Paolo Fagone, Katia Mangano, Santa Mammana, Antonio Pesce, Aurora Pesce, Rosario Caltabiano, Alexandra Giorlandino, Teresa Rosanna Portale, Eugenio Cavalli, Giuseppe A.G. Lombardo, Marinella Coco, Stefano Puleo, Ferdinando Nicoletti
Pages: 747-752
Published online on: 29 June 2015

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Article

Myocardin-related transcription factor-A-overexpressing bone marrow stem cells protect cardiomyocytes and alleviate cardiac damage in a rat model of acute myocardial infarction

Ze Zhong, Jia-Qing Hu, Xin-Dong Wu, Yong Sun, Jun Jiang
Pages: 753-759
Published online on: 25 June 2015

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Article

MicroRNA-153 suppresses the osteogenic differentiation of human mesenchymal stem cells by targeting bone morphogenetic protein receptor type II

Yujing Cao, Qiuxia Lv, Cuitian Lv
Pages: 760-766
Published online on: 07 July 2015

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Article

Treatment with PPARδ agonist alleviates non-alcoholic fatty liver disease by modulating glucose and fatty acid metabolic enzymes in a rat model

Xiuli Li, Jin Li, Xiaolan Lu, Huihui Ma, Haitao Shi, Hong Li, Danhong Xie, Lei Dong, Chunlian Liang
Pages: 767-775
Published online on: 01 July 2015

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Article

Aplasia Ras homologue member Ⅰ overexpression inhibits tumor growth and induces apoptosis through inhibition of PI3K/Akt survival pathways in human osteosarcoma MG-63 cells in culture

Kaishan Ye, Shuanke Wang, Yong Yang, Xuewen Kang, Jing Wang, Hua Han
Pages: 776-782
Published online on: 08 July 2015

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Article

Hypoxia promotes vasculogenic mimicry formation by the Twist1-Bmi1 connection in hepatocellular carcinoma

Kun Liu, Baocun Sun, Xiulan Zhao, Xudong Wang, Yanlei Li, Zhiqiang Qiu, Tieju Liu, Qiang Gu, Xueyi Dong, Yanhui Zhang, Yong Wang, Nan Zhao
Pages: 783-791
Published online on: 22 July 2015

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Article

Loquat leaf extract enhances myogenic differentiation, improves muscle function and attenuates muscle loss in aged rats

Bokyung Sung, Seong Yeon Hwang, Min Jo Kim, Minjung Kim, Ji Won Jeong, Cheol Min Kim, Hae Young Chung, Nam Deuk Kim
Pages: 792-800
Published online on: 15 July 2015

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Article

Estradiol attenuates the TGF-β1-induced conversion of primary TAFs into myofibroblasts and inhibits collagen production and myofibroblast contraction by modulating the Smad and Rho/ROCK signaling pathways

He‑Song Jiang, Lei‑Lei Zhu, Zheng Zhang, Hai Chen, Yun Chen, Yu‑Tian Dai
Pages: 801-807
Published online on: 16 July 2015

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Article

YCG063 inhibits Pseudomonas aeruginosa LPS-induced inflammation in human retinal pigment epithelial cells through the TLR2-mediated AKT/NF-κB pathway and ROS-independent pathways

Sung Hwa Paeng, Won Sun Park, Won-Kyo Jung, Dae-Sung Lee, Gi-Young Kim, Yung Hyun Choi, Su-Kil Seo, Won Hee Jang, Jung Sik Choi, Young-Min Lee, Saegwang Park, Il-Whan Choi
Pages: 808-816
Published online on: 30 June 2015

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Article

MicroRNA-1 regulates the proliferation of vascular smooth muscle cells by targeting insulin-like growth factor 1

Kun Liu, Zhang Ying, Xia Qi, Ying Shi, Qiang Tang
Pages: 817-824
Published online on: 08 July 2015

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Article

Overexpression of heparan sulfate 6-O-sulfotransferase-2 enhances fibroblast growth factor-mediated chondrocyte growth and differentiation

Wei Wang, Xichi Ju, Zhengming Sun, Weikun Hou, Lifang Yang, Rui Zhang
Pages: 825-832
Published online on: 01 July 2015

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Article

Interaction of AIM with insulin-like growth factor-binding protein-4

Qiang You, Yan Wu, Nannan Yao, Guannan Shen, Ying Zhang, Liangguo Xu, Guiying Li, Cynthia Ju
Pages: 833-838
Published online on: 26 June 2015

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Article

PLIN2 inhibits insulin-induced glucose uptake in myoblasts through the activation of the NLRP3 inflammasome

Kyung‑Ah Cho, Peter B. Kang
Pages: 839-844
Published online on: 08 July 2015

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Article

Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKCζ and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells

Anna Chiarini, Daisong Liu, Ubaldo Armato, Ilaria Dal Prà
Pages: 845-856
Published online on: 20 July 2015

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Article

Expression of human telomerase reverse transcriptase mediates the senescence of mesenchymal stem cells through the PI3K/AKT signaling pathway

Qiang Zhao, Xue-Yao Wang, Xiao-Xia Yu, Ying-Xian Zhai, Xu He, Shan Wu, Ying-Ai Shi
Pages: 857-864
Published online on: 15 July 2015

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Article

Estrogen suppresses epileptiform activity by enhancing Kv4.2-mediated transient outward potassium currents in primary hippocampal neurons

Yuwen Zhang, Yian Huang, Xu Liu, Guoxiang Wang, Xin Wang, Yun Wang
Pages: 865-872
Published online on: 16 July 2015

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Article

Resveratrol prevents doxorubicin-induced cardiotoxicity in H9c2 cells through the inhibition of endoplasmic reticulum stress and the activation of the Sirt1 pathway

Yu Lou, Zhen Wang, Yi Xu, Ping Zhou, Junxian Cao, Yuanshi Li, Yeping Chen, Junfeng Sun, Lu Fu
Pages: 873-880
Published online on: 20 July 2015

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Article

Unphosphorylated HSP27 (HSPB1) regulates the translation initiation process via a direct association with eIF4E in osteoblasts

Gen Kuroyanagi, Haruhiko Tokuda, Naohiro Yamamoto, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Takanobu Otsuka
Pages: 881-889
Published online on: 07 July 2015

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Article

PBEF promotes the apoptosis of pulmonary microvascular endothelial cells and regulates the expression of inflammatory factors and AQP1 through the MAPK pathways

Guang‑Feng Ming, Xin‑Hua Ma, Dao‑Miao Xu, Zhi‑Yong Liu, Yu‑Hang Ai, Hui‑Xia Liu, Zan‑Hua Shi
Pages: 890-896
Published online on: 13 July 2015

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Article

Protective effects of Notch1 signaling activation against high glucose-induced myocardial cell injury: Analysis of its mechanisms of action

Jian Zhang, Bingong Li, Zeqi Zheng, Ting Kang, Minghui Zeng, Yanhua Liu, Baohua Xia
Pages: 897-903
Published online on: 22 July 2015

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Article

Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro

Zengmei Lan, Zhaoyang Chong, Cong Liu, Danyang Feng, Dihai Fang, Weijin Zang, Jun Zhou
Pages: 904-910
Published online on: 20 July 2015

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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