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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2004 Volume 25 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature

Jason S. Frischer, Jianzhong Huang, Anna Serur, Angela Kadenhe-Chiweshe, Kimberly W. McCrudden, Kathleen O'Toole, Jocelyn Holash, George D. Yancopoulos, Darrell J. Yamashiro, Jessica J. Kandel
Pages: 549-553
Published online on: 01 September 2004

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Article

Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression

David Y. Leger, Bertrand Liagre, Cécile Corbière, Jeanne Cook-Moreau, Jean-Louis Beneytout
Pages: 555-562
Published online on: 01 September 2004

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Article

Growth suppression of esophageal squamous cell carcinoma induced by heavy carbon-ion beams combined with p53 gene transfer

Gaku Oohira, Shigeru Yamada, Takenori Ochiai, Hisahiro Matsubara, Shinichi Okazumi, Koichi Ando, Hirohiko Tsujii, Takaki Hiwasa, Hideaki Shimada
Pages: 563-569
Published online on: 01 September 2004

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Article

A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA

Tomohiro Emura, Norihiko Suzuki, Masahiro Yamaguchi, Hideyuki Ohshimo, Masakazu Fukushima
Pages: 571-578
Published online on: 01 September 2004

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Article

Cyclin D1 overexpression is not a specific grouping marker, but may collaborate with CDC37 in myeloma cells

Yuta Katayama, Akira Sakai, Yoshiko Okikawa, Naohide Oue, Hideki Asaoku, Ayako Sasaki, Fumio Imanaka, Takako Tsujimoto, Yasuo Takimoto, Rie Masuda, Nanae Nakaju, Takemi Otsuki, Wataru Yasui, Akiro Kimura
Pages: 579-595
Published online on: 01 September 2004

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Article

Application of RT-PCR to clinical diagnosis of micrometastasis of colorectal cancer: A translational research study

Osamu Takayama, Hirofumi Yamamoto, Kimimasa Ikeda, Hideyuki Ishida, Takeshi Kato, Masaki Okuyama, Toshiyuki Kanou, Mutsumi Fukunaga, Shusei Tominaga, Shunji Morita, Yujiro Fujie, Hiroki Fukunaga, Masakazu Ikenaga, Masataka Ikeda, Masayuki Ohue, Mitsugu Sekimoto, Nobuteru Kikkawa, Morito Monden
Pages: 597-604
Published online on: 01 September 2004

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Article

Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis

Koichi Ohshima, Kennosuke Karube, Riko Kawano, Takeshi Tsuchiya, Hiroaki Suefuji, Takahiro Yamaguchi, Junji Suzumiya, Masahiro Kikuchii
Pages: 605-613
Published online on: 01 September 2004

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Article

Two subtypes of mucinous colorectal carcinoma characterized by laser scanning cytometry and comparative genomic hybridization

Xiu-Ping Liu, Toshihiko Sato, Atsunori Oga, Kenzou Ikemoto, Shigeto Kawauchi, Eiichi Ikeda, Kohsuke Sasaki
Pages: 615-621
Published online on: 01 September 2004

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Article

Evaluation of Hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: Biodistribution, light dose and drug-light interval effects

William Chin, Weber Lau, Christopher Cheng, Malini Olivo
Pages: 623-629
Published online on: 01 September 2004

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Article

Thiazolidinedione, a peroxisome proliferator-activated receptor-γ ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects

Tetsuya Yoshizumi, Tetsuo Ohta, Itasu Ninomiya, Itsuro Terada, Sachio Fushida, Takashi Fujimura, Gen-Ichi Nishimura, Koichi Shimizu, Shuangqin Yi, Koichi Miwa
Pages: 631-639
Published online on: 01 September 2004

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Article

Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors

Eva Klopocki, Glen Kristiansen, Peter J. Wild, Irina Klaman, Esmeralda Castanos-Velez, Gad Singer, Robert Stöhr, Ronald Simon, Guido Sauter, Haike Leibiger, Lutz Essers, Birgit Weber, Klaus Hermann, André Rosenthal, Arndt Hartmann, Edgar Dahl
Pages: 641-649
Published online on: 01 September 2004

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Article

Bid sensitizes apoptosis induced by chemotherapeutic drugs in hepatocellular carcinoma

Ji Miao, George G. Chen, Suk-Ying Chun, Ernest C.W. Chak, Paul B.S. Lai
Pages: 651-659
Published online on: 01 September 2004

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Article

Flavone inhibition of tumor growth via apoptosis in vitro and in vivo

Yen-Chou Chen, Shing-Chuan Shen, Jyh-Ming Chow, Ching Huai Ko, Shih-Wen Tseng
Pages: 661-670
Published online on: 01 September 2004

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Article

Deregulation of PKB influences antiapoptotic signaling by PKC in breast cancer cells

Dongmei Lu, Jie Huang, Alakananda Basu
Pages: 671-676
Published online on: 01 September 2004

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Article

Doxorubicin potentiates TRAIL cytotoxicity and apoptosis and can overcome TRAIL-resistance in rhabdomyosarcoma cells

R. Komdeur, C. Meijer, M. Van Zweeden, S. De Jong, J. Wesseling, H. J. Hoekstra, W. T.A. Van der Graaf
Pages: 677-684
Published online on: 01 September 2004

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Article

Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas

Yoichiro Ogama, Mamoru Ouchida, Tadashi Yoshino, Sachio Ito, Hidetaka Takimoto, Yasuhiro Shiote, Fumihiko Ishimaru, Mine Harada, Mitsune Tanimoto, Kenji Shimizu
Pages: 685-691
Published online on: 01 September 2004

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Article

Multiple EBNA1-binding sites within oriPI are required for EBNA1-dependent transactivation of the Epstein-Barr virus C promoter

Henrik Zetterberg, Cecilia Boreström, Tina Nilsson, Lars Rymo
Pages: 693-696
Published online on: 01 September 2004

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Article

Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells

Jo Ishizawa, Shuichi Yoshida, Mototsugu Oya, Ryuichi Mizuno, Toshiaki Shinojima, Ken Marumo, Masaru Murai
Pages: 697-702
Published online on: 01 September 2004

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Article

Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with α-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma

Maria Liljefors, Peter Ragnhammar, Bo Nilsson, Gustav Ullenhag, Håkan Mellstedt, Jan-Erik Frödin
Pages: 703-711
Published online on: 01 September 2004

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Article

Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites

Masahiro Inoue, Mutsuko Mukai, Yukou Hamanaka, Masaharu Tatsuta, Masahiro Hiraoka, Shinae Kizaka-Kondoh
Pages: 713-720
Published online on: 01 September 2004

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Article

Loss of caspase-8 activation pathway is a possible mechanism for CDDP resistance in human laryngeal squamous cell carcinoma, HEp-2 cells

Yasuo Toyozumi, Nobuyuki Arima, Shinsuke Izumaru, Seiya Kato, Minoru Morimatsu, Tadashi Nakashima
Pages: 721-728
Published online on: 01 September 2004

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Article

Topoisomerase inhibitors enhance the cytocidal effect of AAV-HSVtk/ganciclovir on head and neck cancer cells

Takeharu Kanazawa, Hiroaki Mizukami, Hiroshi Nishino, Takashi Okada, Yutaka Hanazono, Akihiro Kume, Ken Kitamura, Keiichi Ichimura, Keiya Ozawa
Pages: 729-735
Published online on: 01 September 2004

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Article

Docosahexaenoic acid modulates different genes in cell cycle and apoptosis to control growth of human leukemia HL-60 cells

Lawrence C.-M. Chiu, Elaine Y.-L. Wong, Vincent E.C. Ooi
Pages: 737-744
Published online on: 01 September 2004

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Article

The interaction of tenascin-C with fibronectin modulates the migration and specific metalloprotease activity in human mesothelioma cell lines of different histotype

Anna Giuffrida, Susanna Scarpa, Patrizia Birarelli, Andrea Modesti
Pages: 745-750
Published online on: 01 September 2004

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Article

Identification and characterization of a novel human FOXK1 gene in silico

Jeffrey T.-J. Huang, Vivian Lee
Pages: 751-757
Published online on: 01 September 2004

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Article

Identification and characterization of TMEM24 family genes in silico

Masuko Katoh, Masaru Katoh
Pages: 759-764
Published online on: 01 September 2004

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Article

Identification and characterization of human DFNA5L, mouse Dfna5l, and rat Dfna5l genes in silico

Masuko Katoh, Masaru Katoh
Pages: 765-770
Published online on: 01 September 2004

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Article

Allelic variation of BAT-25 and BAT-26 mononucleotide repeat loci in tumours from a group of young women with breast cancer

Y. A. Luqmani, M. Mathew
Pages: 771-775
Published online on: 01 September 2004

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Article

Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines

Adriana Brondani Da Rocha, Andrea Regner, Ivana Grivicich, Daniel Pretto Schunemann, Celito Diel, Giovana Kovaleski, Caroline Brunetto De Farias, Edlaine Mondadori, Leonardo Almeida, Aroldo Braga Filho, Gilberto Schwartsmann
Pages: 777-785
Published online on: 01 September 2004

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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