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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2005 Volume 27 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Molecular characterization of breast cancer cell lines by a low-density microarray

Francoise De Longueville, Marc Lacroix, Anna-Maria Barbuto, Vincent Bertholet, Dominique Gallo, Denis Larsimont, Laurence Marcq, Nathalie Zammatteo, Sophie Boffe, Guy Leclercq, Jose Remacle
Pages: 881-892
Published online on: 01 October 2005

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Article

Combined treatment of leukemia cells with vitamin K2 and 1α,25-dihydroxy vitamin D3 enhances monocytic differentiation along with becoming resistant to apoptosis by induction of cytoplasmic p21CIP1

Tomotaka Iguchi, Keisuke Miyazawa, Minoru Asada, Akihiko Gotoh, Shuki Mizutani, Kazuma Ohyashiki
Pages: 893-900
Published online on: 01 October 2005

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Article

Efficacy of oncolytic reovirus against liver metastasis from pancreatic cancer in immunocompetent models

Yoshihisa Himeno, Tsuyoshi Etoh, Toshifumi Matsumoto, Masayuki Ohta, Akira Nishizono, Seigo Kitano
Pages: 901-906
Published online on: 01 October 2005

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Article

The inhibitory effect and possible mechanisms of D-allose on cancer cell proliferation

Li Sui, Youyi Dong, Yasuo Watanabe, Fuminori Yamaguchi, Naoya Hatano, Ikuko Tsukamoto, Ken Izumori, Masaaki Tokuda
Pages: 907-912
Published online on: 01 October 2005

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Article

The effects of non-selective, preferential-selective and selective COX-inhibitors on the growth of experimental and human tumors in mice related to prostanoid receptors

Christian Cahlin, Johan Gelin, Marianne Andersson, Christina Lönnroth, Kent Lundholm
Pages: 913-923
Published online on: 01 October 2005

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Article

Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells

K. Inomata, A. Oga, S. Kawauchi, T. Furuya, K. Sasaki
Pages: 925-931
Published online on: 01 October 2005

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Article

The role of T-fimbrin in the response to DNA damage: Silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

Hiroshi Ikeda, Yasushi Sasaki, Toshihisa Kobayashi, Hiromu Suzuki, Hiroaki Mita, Minoru Toyota, Fumio Itoh, Yasuhisa Shinomura, Takashi Tokino, Kohzoh Imai
Pages: 933-940
Published online on: 01 October 2005

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Article

Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-κB inhibitor

Annette Hansson, Yarí E. Marín, Junghan Suh, Arnold B. Rabson, Suzie Chen, Eliezer Huberman, Richard L. Chang, Allan H. Conney, Xi Zheng
Pages: 941-948
Published online on: 01 October 2005

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Article

Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression

Anthony Nguyen, Andrea Rosner, Tatjana Milovanovic, Christopher Hope, Kestutis Planutis, Baisakhi Saha, Benjaporn Chaiwun, Fritz Lin, S. Ashraf Imam, J. Lawrence Marsh, Randall F. Holcombe
Pages: 949-956
Published online on: 01 October 2005

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Article

Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum

Dong Hoon Kim, Jong Woo Kim, Joong Hyeon Cho, Sun Heum Baek, Sanjay Kakar, Grace E. Kim, Marvin H. Sleisenger, Young S. Kim
Pages: 957-964
Published online on: 01 October 2005

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Article

Magnetically labeled human natural killer cells, accumulated in vitro by an external magnetic force, are effective against HOS osteosarcoma cells

Yuko Nakashima, Masataka Deie, Shinobu Yanada, Patrick Sharman, Mitsuo Ochi
Pages: 965-971
Published online on: 01 October 2005

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Article

Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas

Noriaki Tokumoto, Satoshi Ikeda, Yasuyo Ishizaki, Takeshi Kurihara, Shinji Ozaki, Masahiko Iseki, Yosuke Shimizu, Toshiyuki Itamoto, Koji Arihiro, Masazumi Okajima, Toshimasa Asahara
Pages: 973-980
Published online on: 01 October 2005

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Article

Parathyroid hormone-related protein as a common target molecule in specific immunotherapy for a wide variety of tumor types

Yoshimi Arima, Satoko Matsueda, Hirohisa Yano, Mamoru Harada, Kyogo Itoh
Pages: 981-988
Published online on: 01 October 2005

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Article

The usefulness of 1.5 harmonic imaging ultrasonography with Levovist in the diagnosis of focal hepatic tumors

Kouji Yamamoto, Katsuya Shiraki, Shigeo Nakanishi, Hiroyuki Fuke, Akira Hashimoto, Atsuya Shimizu, Takeshi Nakano
Pages: 989-995
Published online on: 01 October 2005

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Article

Trefoil factor family mRNA and protein expression in pterygium

Pierre-Olivier Lafontaine, Murielle Arnal, Nelly Buron, Eric Solary, Alain M. Bron, Bruce R. Westley, Felicity E.B. May, Jacques Bara, Christian Gespach, Catherine Creuzot-Garcher
Pages: 997-1003
Published online on: 01 October 2005

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Article

Comparison of extracellular matrix and apoptotic markers between benign lesions and carcinomas in human breast

Fortunata Vasaturo, Elvira Sallusti, Angela Gradilone, Carolina Malacrino, Tiziana Nardo, Grazia Avagnano, Anna Maria Aglianò, Teresa Granato, Bruno De Vincenzi, Giuseppe Coppotelli, Antonella Marzullo, Giuseppe Soda, Lucilla Simonelli, Mauro Modesti, Susanna Scarpa
Pages: 1005-1011
Published online on: 01 October 2005

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Article

The role of actin in the apoptotic cell death of P19 embryonal carcinoma cells

Jakub Neradil, Renata Veselská, Augustin Svoboda
Pages: 1013-1021
Published online on: 01 October 2005

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Article

RAS mutations are uncommon in multiple myeloma and other monoclonal gammopathies

Paloma Martín, Almudena Santón, Mónica García-Cosío, Carmen Bellas
Pages: 1023-1028
Published online on: 01 October 2005

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Article

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression

Rouslan Kotchetkov, Pablo Hernáiz Driever, Jaroslav Cinatl, Martin Michaelis, Jana Karaskova, Roman Blaheta, Jeremy A. Squire, Andreas Von Deimling, Jussi Moog, Jindrich Cinatl
Pages: 1029-1037
Published online on: 01 October 2005

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Article

Interleukin-2 and 13-cis retinoic acid as maintenance therapy in advanced ovarian cancer

Francesco Recchia, Gaetano Saggio, Alisia Cesta, Giampiero Candeloro, Antonio Nuzzo, Marco Lombardo, Gaspare Carta, Silvio Rea
Pages: 1039-1046
Published online on: 01 October 2005

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Article

Proteasome inhibition improves fractionated radiation treatment against non-small cell lung cancer: An antioxidant connection

Kristopher Ray Grimes, Chotiros Daosukho, Yunfeng Zhao, Ali Meigooni, William St. Clair
Pages: 1047-1052
Published online on: 01 October 2005

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Article

Long-term regression of the murine mammary adenocarcinoma, LM3, by repeated photodynamic treatments using meso-tetra (4-N-methylpyridinium) porphine

Lucas L. Colombo, Silvia I. Vanzulli, Angeles Villanueva, Magdalena Cañete, Angeles Juarranz, Juan C. Stockert
Pages: 1053-1059
Published online on: 01 October 2005

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Article

In vitro inhibition of matriptase prevents invasive growth of cell lines of prostate and colon carcinoma

Diana Förbs, Stefan Thiel, Maria C. Stella, Anne Stürzebecher, Andrea Schweinitz, Torsten Steinmetzer, Jörg Stürzebecher, Kerstin Uhland
Pages: 1061-1070
Published online on: 01 October 2005

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Article

Bovine seminal ribonuclease is cytotoxic for both malignant and normal telomerase-positive cells

Maria Viola, Massimo Libra, Daniela Callari, Fulvia Sinatra, Daniele Spada, Davide Noto, Giovanni Emmanuele, Fabrizio Romano, Maurizio Averna, Franca Maria Pezzino, Franca Stivala, Salvatore Travali
Pages: 1071-1077
Published online on: 01 October 2005

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Article

Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma

Takashi Himoto, Shigeki Kuriyama, Jian-Ying Zhang, Edward K.L. Chan, Yasuhiko Kimura, Tsutomu Masaki, Naohito Uchida, Mikio Nishioka, Eng M. Tan
Pages: 1079-1085
Published online on: 01 October 2005

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Article

The cooperative transforming effects of PAX3-FKHR and IGF-II on mouse myoblasts

W. Wang, M. Slevin, S. Kumar, P. Kumar
Pages: 1087-1096
Published online on: 01 October 2005

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Article

Anti-proliferative activity of haloperidol in B16 mouse and human SK-MEL-28 melanoma cell lines

Jardena Nordenberg, Israela Perlmutter, Gad Lavie, Einat Beery, Orit Uziel, Chaya Morgenstern, Eyal Fenig, Abraham Weizman
Pages: 1097-1103
Published online on: 01 October 2005

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Article

The cachectic mediator proteolysis inducing factor activates NF-κB and STAT3 in human Kupffer cells and monocytes

Tammy M. Watchorn, Nabil Dowidar, Cornelis H.C. Dejong, Ian D. Waddell, O. James Garden, James A. Ross
Pages: 1105-1111
Published online on: 01 October 2005

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Review

Old and new insights into the mechanisms of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine (Review)

Eric Van Den Neste, Sabine Cardoen, Fritz Offner, Françoise Bontemps
Pages: 1113-1124
Published online on: 01 October 2005

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Article

Combination therapy for advanced pancreatic cancer using Herceptin™ plus chemotherapy

Peter Büchler, Howard A. Reber, Guido Eibl, Mendel A. Roth, Markus W. Büchler, Helmut Friess, William H. Isacoff, Oscar J. Hines
Pages: 1125-1130
Published online on: 01 October 2005

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Article

2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) exhibits p53-dependent and -independent antiproliferative activity in human nasopharyngeal carcinoma cells in vitro and in vivo

T. H. Nguyen, C. K. Ong, E. Wong, C. T. Leong, L. Panasci, H. Huynh
Pages: 1131-1140
Published online on: 01 October 2005

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Article

Tumor-immune memory T cells from the bone marrow exert GvL without GvH reactivity in advanced metastasized cancer

Volker Schirrmacher, Philipp Beckhove, Carmen Choi, Andreas Griesbach, Yolanda Mahnke
Pages: 1141-1149
Published online on: 01 October 2005

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Article

Distinct expression of Survivin splice variants in breast carcinomas

Frédérique Vegran, Romain Boidot, Claire Oudin, Jean-Marc Riedinger, Sarab Lizard-Nacol
Pages: 1151-1157
Published online on: 01 October 2005

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Review

Non-anti-coagulant heparins: A promising approach for prevention of tumor metastasis (Review)

Michael Kragh, Frosty Loechel
Pages: 1159-1167
Published online on: 01 October 2005

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Momo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.k.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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