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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2006 Volume 29 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: Molecular signatures of chemoresistant tumors

Sylvain L'Espérance, Ion Popa, Magdalena Bachvarova, Marie Plante, Nancy Patten, Lin Wu, Bernard Têtu, Dimcho Bachvarov
Pages: 5-24
Published online on: 01 July 2006

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Article

Restoration of tissue factor pathway inhibitor inhibits invasion and tumor growth in vitro and in vivo in a malignant meningioma cell line

Shakuntala Kondraganti, Christopher S. Gondi, Meena Gujrati, Ian McCutcheon, Dzung H. Dinh, Jasti S. Rao, William C. Olivero
Pages: 25-32
Published online on: 01 July 2006

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Article

MUC5AC mucin gene regulation in pancreatic cancer cells

Shingo Kato, Ryota Hokari, Suzanne Crawley, James Gum, Dae-Ho Ahn, Jong-Woo Kim, Sung-Won Kwon, Soichiro Miura, Carol B. Basbaum, Young S. Kim
Pages: 33-40
Published online on: 01 July 2006

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Article

Human DEAD-box/RNA unwindase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cells

Yukihiro Akao, Kenji Matsumoto, Kenji Ohguchi, Yoshihito Nakagawa, Hitoshi Yoshida
Pages: 41-48
Published online on: 01 July 2006

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Article

Characterization of MUC1 glycoprotein on prostate cancer for selection of targeting molecules

Patricia A. Burke, Jeffrey P. Gregg, Brandon Bakhtiar, Laurel A. Beckett, Gerald L. Denardo, Huguette Albrecht, Ralph W. De Vere White, Sally J. De Nardo
Pages: 49-55
Published online on: 01 July 2006

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Article

Identification of gene expression signatures for molecular classification in human leukemia cells

Ju Han Song, Hyeoung-Joon Kim, Chang Hyun Lee, Seung Jun Kim, Seung Yong Hwang, Tae Sung Kim
Pages: 57-64
Published online on: 01 July 2006

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Article

Elevated pleural fluid RCAS1 is a diagnostic marker and outcome predictor in lung cancer patients

Keisuke Aoe, Akio Hiraki, Koichi Yamazaki, Yuichi Nakamura, Tomoyuki Murakami, Tadashi Maeda, Masaharu Nishimura, Kazuro Sugi, Hiroshi Ueoka
Pages: 65-72
Published online on: 01 July 2006

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Article

PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules

Koji Furukawa, Yoshiaki Kumon, Hironobu Harada, Shohei Kohno, Shigeyuki Nagato, Mikio Teraoka, Satoshi Fujiwara, Kou Nakagawa, Katsuyuki Hamada, Takanori Ohnishi
Pages: 73-81
Published online on: 01 July 2006

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Article

Comparative study of gene expression by cDNA microarray in human colorectal cancer tissues and normal mucosa

Michele Bianchini, Estrella Levy, Cinzia Zucchini, Victor Pinski, Carlos Macagno, Paola De Sanctis, Luisa Valvassori, Paolo Carinci, José Mordoh
Pages: 83-94
Published online on: 01 July 2006

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Article

Expression of RHAMM/CD168 and other tumor-associated antigens in patients with B-cell chronic lymphocytic leukemia

K. Giannopoulos, L. Li, A. Bojarska-Junak, J. Rolinski, A. Dmoszynska, I. Hus, J. Greiner, C. Renner, H. Döhner, M. Schmitt
Pages: 95-103
Published online on: 01 July 2006

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Article

Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer

Takehiko Ochiumi, Yasuhiko Kitadai, Shinji Tanaka, Morihisa Akagi, Masaharu Yoshihara, Kazuaki Chayama
Pages: 105-116
Published online on: 01 July 2006

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Article

Aberrant expression of histone deacetylase 6 in oral squamous cell carcinoma

Takumi Sakuma, Katsuhiro Uzawa, Takeshi Onda, Masashi Shiiba, Hidetaka Yokoe, Takahiko Shibahara, Hideki Tanzawa
Pages: 117-124
Published online on: 01 July 2006

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Article

Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice

Cheryl H. Baker, Jose G. Trevino, Justin M. Summy, Fahao Zhang, Alexis Caron, Mark Nesbit, Gary E. Gallick, Isaiah J. Fidler
Pages: 125-138
Published online on: 01 July 2006

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Article

The oncogenic B-raf V599E mutation occurs more frequently in melanomas at sun-protected body sites

Martin Deichmann, Dieter Krahl, Marianne Thome, Kirsten Wüst, Judith Hassanzadeh, Burkhard Helmke
Pages: 139-145
Published online on: 01 July 2006

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Article

Differential regulation of p73 variants in response to cisplatin treatment in SH-SY5Y neuroblastoma cells

Karine Million, Émilie Horvilleur, David Goldschneider, Malik Agina, Gilda Raguénez, Frédéric Tournier, Jean Bénard, Sétha Douc-Rasy
Pages: 147-154
Published online on: 01 July 2006

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Article

The decreased susceptibility of metastatic melanoma cells to killing involves an alteration of CTL reactivity

Ahmed Gassara, Yosra Messai, Catherine Gaudin, Soraya Abouzahr, Adbelali Jalil, Maryam Diarra-Mehrpour, Florence Faure, Catherine Richon, Marie-Françoise Avril, Jos Even, Salem Chouaib
Pages: 155-161
Published online on: 01 July 2006

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Review

FGF signaling network in the gastrointestinal tract (Review)

Masuko Katoh, Masaru Katoh
Pages: 163-168
Published online on: 01 July 2006

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Article

A novel synthetic drug, LB-18, closely related to lembehyne-A derived from a marine sponge, induces caspase-independent cell death to human neuroblastoma cells

Moriatsu Izumi, Shingo Yogosawa, Shunji Aoki, Hirotsuna Watanabe, Jun Kamiyama, Yoshinori Takahara, Yoshihiro Sowa, Motomasa Kobayashi, Hajime Hosoi, Tohru Sugimoto, Toshiyuki Sakai
Pages: 169-173
Published online on: 01 July 2006

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Article

HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells

Katsuhiro Tofuku, Masahiro Yokouchi, Takashi Murayama, Shusaku Minami, Setsuro Komiya
Pages: 175-183
Published online on: 01 July 2006

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Review

NF-κB, inflammation and pancreatic carcinogenesis: NF-κB as a chemoprevention target (Review)

Zhiquan Zhang, Basil Rigas
Pages: 185-192
Published online on: 01 July 2006

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Article

Elevated levels of circulating insulin-like growth factor-I, IGF-binding globulin-3 and testosterone predict hormone-dependent breast cancer in postmenopausal women: A case-control study

Zsuzsanna Kahán, János Gardi, Tibor Nyári, Imre Földesi, Rozália Hajnal-Papp, Katalin Ormándi, György Lázár, László Thurzó, Andrew V. Schally
Pages: 193-200
Published online on: 01 July 2006

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Article

A novel DNMT3B subfamily, ΔDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer

Luo Wang, Jie Wang, Shiyong Sun, Marivonne Rodriguez, Ping Yue, Se Jin Jang, Li Mao
Pages: 201-207
Published online on: 01 July 2006

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Article

Anti-angiogenic action of plasma hyaluronan binding protein in human umbilical vein endothelial cells

Ji Won Jeon, Hyun Seok Song, Eun-Joung Moon, Shi-Young Park, Myung Jin Son, Seung Youn Jung, Ji Tae Kim, Do-Hyun Nam, Nam-Ho Choi-Miura, Kyu-Won Kim, Yung-Jin Kim
Pages: 209-215
Published online on: 01 July 2006

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Article

Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho

Toshiyuki Kusama, Mutsuko Mukai, Masaharu Tatsuta, Hiroyuki Nakamura, Masahiro Inoue
Pages: 217-223
Published online on: 01 July 2006

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Article

Expression analysis of genes involved in oxaliplatin response and development of oxaliplatin-resistant HT29 colon cancer cells

C. Plasencia, E. Martínez-Balibrea, A. Martinez-Cardús, D. I. Quinn, A. Abad, N. Neamati
Pages: 225-235
Published online on: 01 July 2006

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Article

Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells

Fortunata Iacopino, Gina Lama, Cristiana Angelucci, Gigliola Sica
Pages: 237-247
Published online on: 01 July 2006

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Article

LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells

Ken Ohnishi, Jun-Ichi Yasumoto, Akihisa Takahashi, Takeo Ohnishi
Pages: 249-253
Published online on: 01 July 2006

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Article

A domain responsible for HIF-1α degradation by YC-1, a novel anticancer agent

Hye-Lim Kim, Eun-Jin Yeo, Yang-Sook Chun, Jong-Wan Park
Pages: 255-260
Published online on: 01 July 2006

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Article

The role of cisplatin and NAMI-A plasma-protein interactions in relation to combination therapy

Isam Khalaila, Alberta Bergamo, Francois Bussy, Gianni Sava, Paul J. Dyson
Pages: 261-268
Published online on: 01 July 2006

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Article

Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells

Changlin Zhou, Lihua Qiu, Yun Sun, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wen Di, Bingfang Yan, Yinsheng Wan
Pages: 269-278
Published online on: 01 July 2006

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Article

Long-term suppression of telomerase expression in HeLa cell clones, transfected with an expression vector carrying siRNA targeting hTERT mRNA

Kaisa Kurvinen, Stina Syrjänen, Bo Johansson
Pages: 279-288
Published online on: 01 July 2006

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Article

Inhibition of synuclein-γ expression increases the sensitivity of breast cancer cells to paclitaxel treatment

Yue Zhou, Satoru Inaba, Jingwen Liu
Pages: 289-295
Published online on: 01 July 2006

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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