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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2006 Volume 29 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Gene expression profiling of lymph node metastasis by oligomicroarray analysis using laser microdissection in esophageal squamous cell carcinoma

Yasuto Uchikado, Hiroshi Inoue, Naotsugu Haraguchi, Koshi Mimori, Shoji Natsugoe, Hiroshi Okumura, Takashi Aikou, Masaki Mori
Pages: 1337-1347
Published online on: 01 December 2006

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Article

SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA

Sateesh Kunigal, Christopher S. Gondi, Meena Gujrati, Sajani S. Lakka, Dzung H. Dinh, William C. Olivero, Jasti S. Rao
Pages: 1349-1357
Published online on: 01 December 2006

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Article

In vivo efficacy of systemic tumor targeting of a viral RNA vector with oncolytic properties using a bispecific adapter protein

Huijie Bian, Holger Wilden, Philippe Fournier, Ben Peeters, Volker Schirrmacher
Pages: 1359-1369
Published online on: 01 December 2006

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Article

Novel anti-denatured collagen humanized antibody D93 inhibits angiogenesis and tumor growth: An extracellular matrix-based therapeutic approach

Flavia Pernasetti, Jeffrey Nickel, Derek Clark, Patrick A. Baeuerle, Dennis Van Epps, Bruce Freimark
Pages: 1371-1379
Published online on: 01 December 2006

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Article

Marine sponge-derived polymeric alkylpyridinium salts as a novel tumor chemotherapeutic targeting the cholinergic system in lung tumors

Laura Paleari, Sonya Trombino, Carla Falugi, Lorenzo Gallus, Sebastiano Carlone, Cristiano Angelini, Kristina Sepcic, Tom Turk, Marco Faimali, Douglas M. Noonan, Adriana Albini
Pages: 1381-1388
Published online on: 01 December 2006

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Article

Different mechanisms of mitotic instability in cancer cell lines

Alexandra Klein, Klaus D. Zang, Wolf-Ingo Steudel, Steffi Urbschat
Pages: 1389-1396
Published online on: 01 December 2006

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Article

Enhancing cisplatin sensitivity in MCF-7 human breast cancer cells by down-regulation of Bcl-2 and cyclin D1

Christina Westmose Yde, Olaf-Georg Issinger
Pages: 1397-1404
Published online on: 01 December 2006

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Article

Adenovirus-mediated interferon-β gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice

Juwon Lee, Amy Wang, Qiande Hu, Shan Lu, Zhongyun Dong
Pages: 1405-1412
Published online on: 01 December 2006

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Article

RNF2 interacts with the linker region of the human P-glycoprotein

Prema S. Rao, Kavita B. Mallya, Kalkunte S. Srivenugopal, K. C. Balaji, U. Subrahmanyeswara Rao
Pages: 1413-1419
Published online on: 01 December 2006

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Article

Establishment of three malignant peripheral nerve sheath tumor cell lines, FU-SFT8611, 8710 and 9817: Conventional and molecular cytogenetic characterization

Mikiko Aoki, Kazuki Nabeshima, Jun Nishio, Masako Ishiguro, Chikako Fujita, Kaori Koga, Makoto Hamasaki, Yasuhiko Kaneko, Hiroshi Iwasaki
Pages: 1421-1428
Published online on: 01 December 2006

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Article

Targeting of cholecystokinin B/gastrin receptor in colonic, pancreatic and hepatocellular carcinoma cell lines

Kay Savage, H. Anne Waller, Mark Stubbs, Korsa Khan, Susan A. Watson, Philip A. Clarke, Steve Grimes, Dov Michaeli, Amar P. Dhillon, Martyn E. Caplin
Pages: 1429-1435
Published online on: 01 December 2006

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Article

Modulation of novel DNA adducts during human uterine cervix cancer progression

Srivani Ravoori, Manicka V. Vadhanam, Diane D. Davey, Cidambi Srinivasan, Bala Nagarajan, Ramesh C. Gupta
Pages: 1437-1443
Published online on: 01 December 2006

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Article

Identification of ID2 associated with invasion of hepatitis C virus-related hepatocellular carcinoma by gene expression profile

Ryouichi Tsunedomi, Norio Iizuka, Hisafumi Yamada-Okabe, Takao Tamesa, Toshimasa Okada, Kazuhiko Sakamoto, Motonari Takashima, Takeshi Hamaguchi, Takanobu Miyamoto, Shunji Uchimura, Yoshihiko Hamamoto, Mamoru Yamada, Masaaki Oka
Pages: 1445-1451
Published online on: 01 December 2006

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Article

CHK negatively regulates Lyn kinase and suppresses pancreatic cancer cell invasion

Yigong Fu, Radoslaw Zagozdzon, Ron Avraham, Hava Karsenty Avraham
Pages: 1453-1458
Published online on: 01 December 2006

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Article

May P-glycoprotein status be used to stratify high-grade osteosarcoma patients? Results from the Italian/Scandinavian Sarcoma Group 1 treatment protocol

Massimo Serra, Michela Pasello, Maria Cristina Manara, Katia Scotlandi, Stefano Ferrari, Franco Bertoni, Mario Mercuri, Thor Andreas Alvegard, Piero Picci, Gaetano Bacci, Sigbjørn Smeland
Pages: 1459-1468
Published online on: 01 December 2006

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Article

The up-regulation of type I interferon receptor gene plays a key role in hepatocellular carcinoma cells in the synergistic antiproliferative effect by 5-fluorouracil and interferon-α

Shinji Oie, Mayumi Ono, Hirohisa Yano, Yuichiro Maruyama, Tadafumi Terada, Yuji Yamada, Takato Ueno, Masamichi Kojiro, Kazuyuki Hirano, Michihiko Kuwano
Pages: 1469-1478
Published online on: 01 December 2006

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Review

The tumour-Clostridium phenomenon: 50 years of developmental research (Review)

Willi Schmidt, Eva-Maria Fabricius, Ulrich Schneeweiss
Pages: 1479-1492
Published online on: 01 December 2006

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Article

The hollow fibre model - facilitating anti-cancer pre-clinical pharmacodynamics and improving animal welfare

Marie Suggitt, Patricia A. Cooper, Steven D. Shnyder, Michael C. Bibby
Pages: 1493-1499
Published online on: 01 December 2006

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Article

Apoptosis of liver cancer cells by vitamin K2 and enhancement by MEK inhibition

Kazuya Matsumoto, Jun-Ichi Okano, Takakazu Nagahara, Yoshikazu Murawaki
Pages: 1501-1508
Published online on: 01 December 2006

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Article

Leptomycin B, a metabolite of Streptomyces, inhibits the expression of inducible nitric oxide synthase in BV2 microglial cells

Byeong-Churl Jang, Su-Haeng Sung, Jong-Gu Park, Jong-Wook Park, Min-Ho Suh, In-Hak Choi, Minoru Yoshida, Sun-Kyun Yoo, Seong-Il Suh
Pages: 1509-1515
Published online on: 01 December 2006

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Article

High dose-rate brachytherapy of prostate cancer utilising Iridium-192 after-loading technique: Technical and methodological aspects

M. Edgren, A. M. Ekelund, P. Albertsson, L. M. Lundberg, A. Ullen, S. Levitt, S. Nilsson, B. Lennernäs
Pages: 1517-1524
Published online on: 01 December 2006

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Article

Response of neuroblastoma cells to ionizing radiation: Modulation of in vitro invasiveness and angiogenesis of human microvascular endothelial cells

Unmesh Jadhav, Sanjeeva Mohanam
Pages: 1525-1531
Published online on: 01 December 2006

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Article

Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1α-independent manner

A. Miyoshi, Y. Kitajima, T. Ide, K. Ohtaka, H. Nagasawa, Y. Uto, H. Hori, K. Miyazaki
Pages: 1533-1539
Published online on: 01 December 2006

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Article

RASSF1A suppresses oncogenic H-Ras-induced c-Jun N-terminal kinase activation

Young A. Yoo, Ah Ram Na, Myeong-Sok Lee, Sukjoon Yoon, Jun Suk Kim
Pages: 1541-1547
Published online on: 01 December 2006

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Article

Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7β-hydroxycholesterol and 7β-hydroxysitosterol

Stamatiki Roussi, Francine Gossé, Dalal Aoudé-Werner, Xin Zhang, Philippe Geoffroy, Michel Miesch, Eric Marchioni, Francis Raul
Pages: 1549-1554
Published online on: 01 December 2006

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Article

Anti-cancer vaccine candidates in specific immunotherapy for bladder carcinoma

Yoshihiro Komohara, Mamoru Harada, Yoshimi Arima, Shigetaka Suekane, Masanori Noguchi, Akira Yamada, Kyogo Itoh, Kei Matsuoka
Pages: 1555-1560
Published online on: 01 December 2006

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Article

Resveratrol induces apoptosis in transformed follicular lymphoma OCI-LY8 cells: Evidence for a novel mechanism involving inhibition of BCL6 signaling

Anthony C. Faber, Thomas C. Chiles
Pages: 1561-1566
Published online on: 01 December 2006

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Article

Depletion of Treg cells inhibits minimal residual disease after surgery of HPV16-associated tumours

Jana Símová, Jan Bubeník, Jana Bieblová, Rodney Alexander Rosalia, Jan Fric, Milan Reinis
Pages: 1567-1571
Published online on: 01 December 2006

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Article

MEK ablation in MCF-7 cells blocks DNA synthesis induced by serum, but not by estradiol or growth factors

Norman R. Estes, Jaideep V. Thottassery, Louise Westbrook, Francis G. Kern
Pages: 1573-1580
Published online on: 01 December 2006

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Article

Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures

Yuelin Zhu, Antai Wang, Minetta C. Liu, Alan Zwart, Richard Y. Lee, Ann Gallagher, Yue Wang, William R. Miller, J. Michael Dixon, Robert Clarke
Pages: 1581-1589
Published online on: 01 December 2006

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Article

Identification of apolipoprotein D as a novel inhibitor of osteopontin-induced neoplastic transformation

Dachuan Jin, Mohamed El-Tanani, Frederick Charles Campbell
Pages: 1591-1599
Published online on: 01 December 2006

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Article

Genetic analysis of peroxisome proliferator-activated receptor γ1 splice variants in human colorectal cell lines

Cathy Fiatte, Cécile Huin, Isabelle Bertin, Thécla Lesuffleur, Arnaud Pluvinet, Nadège Touche, François Plénat, Michel Dauça, Lionel Domenjoud, Hervé Schohn
Pages: 1601-1610
Published online on: 01 December 2006

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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