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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2007 Volume 30 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Global analysis of chromosome X gene expression in primary cultures of normal ovarian surface epithelial cells and epithelial ovarian cancer cell lines

Marie-Hélène Benoît, Thomas J. Hudson, Georges Maire, Jeremy A. Squire, Suzanna L. Arcand, Diane Provencher, Anne-Marie Mes-Masson, Patricia N. Tonin
Pages: 5-17
Published online on: 01 January 2007

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Article

ERG upregulation and related ETS transcription factors in prostate cancer

Kari Rostad, Monica Mannelqvist, Ole Johan Halvorsen, Anne Margrete Øyan, Trond Hellem Bø, Laila Stordrange, Sue Olsen, Svein Andreas Haukaas, Biaoyang Lin, Leroy Hood, Inge Jonassen, Lars Andreas Akslen, Karl-Henning Kalland
Pages: 19-32
Published online on: 01 January 2007

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Article

Gene expression studies of hepatitis virus-induced woodchuck hepatocellular carcinoma in correlation with human results

Fangjing Wang, Paul W. Anderson, Nicolas Salem, Yu Kuang, Bud C. Tennant, Zhenghong Lee
Pages: 33-44
Published online on: 01 January 2007

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Article

In vivo imaging and characterization of hypoxia-induced neovascularization and tumor invasion

Gina F. Lungu, Meng-Lin Li, Xueyi Xie, Lihong V. Wang, George Stoica
Pages: 45-54
Published online on: 01 January 2007

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Article

Gene expression profile as a prognostic factor in high-grade gliomas

Tomasz Czernicki, Jolanta Zegarska, Leszek Paczek, Bozena Cukrowska, Wieslawa Grajkowska, Agnieszka Zajaczkowska, Kazimierz Brudzewski, Jan Ulaczyk, Andrzej Marchel
Pages: 55-64
Published online on: 01 January 2007

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Article

KLF6: Mutational analysis and effect on cancer cell proliferation

Dong Yin, Naoki Komatsu, Carl W. Miller, Alexey M. Chumakov, Alberto Marschesky, Robert McKenna, Keith L. Black, H. Phillip Koeffler
Pages: 65-72
Published online on: 01 January 2007

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Article

Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: Correlation with tissue insulin levels

Razvan T. Radulescu, Carla Hufnagel, Peter Luppa, Heide Hellebrand, Wen-Liang Kuo, Marsha Rich Rosner, Nadia Harbeck, Cecylia Giersig, Alfons Meindl, Manfred Schmitt, Gregor Weirich
Pages: 73-80
Published online on: 01 January 2007

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Article

Cellular expression, localization and interactions of the product of the human MOST-1 gene associated with breast and prostate cancers

Jeanne M.M. Tan, Vincent T.K. Chow
Pages: 81-89
Published online on: 01 January 2007

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Article

Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers

Satish Babu Moparthi, Gunnar Arbman, Åsa Wallin, Hany Kayed, Jörg Kleeff, Hanswalter Zentgraf, Xiao-Feng Sun
Pages: 91-95
Published online on: 01 January 2007

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Article

Serum anti-myomegalin antibodies in patients with esophageal squamous cell carcinoma

Hideaki Shimada, Mari Kuboshima, Tooru Shiratori, Yoshihiro Nabeya, Atsushi Takeuchi, Hiroaki Takagi, Fumio Nomura, Masaki Takiguchi, Takenori Ochiai, Takaki Hiwasa
Pages: 97-103
Published online on: 01 January 2007

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Article

Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: Involvement in the early stages of hepatocarcinogenesis

Takako Nonomura, Tsutomu Masaki, Asahiro Morishita, Gong Jian, Naohito Uchida, Takashi Himoto, Kunihiko Izuishi, Hisakazu Iwama, Hitoshi Yoshiji, Seishiro Watanabe, Kazutaka Kurokohchi, Shigeki Kuriyama
Pages: 105-111
Published online on: 01 January 2007

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Article

Integrin-linked kinase: A hypoxia-induced anti-apoptotic factor exploited by cancer cells

Elizabeth R. Abboud, Seth B. Coffelt, Yanira G. Figueroa, Kevin J. Zwezdaryk, Anne B. Nelson, Deborah E. Sullivan, Cindy B. Morris, Yan Tang, Barbara S. Beckman, Aline B. Scandurro
Pages: 113-122
Published online on: 01 January 2007

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Article

Autoantibodies to the inhibitor of apoptosis protein survivin in patients with brain tumors

Ariane Söling, Eva-Maria Plugge, Marc Schmitz, Bernd Weigle, Roland Jacob, Jörg Illert, Hans-Jürgen Holzhausen, Nikolai G. Rainov
Pages: 123-128
Published online on: 01 January 2007

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Article

The gene expression profile represents the molecular nature of liver metastasis in colorectal cancer

Makoto Yamasaki, Ichiro Takemasa, Takamichi Komori, Shouji Watanabe, Mitsugu Sekimoto, Yuichiro Doki, Kenichi Matsubara, Morito Monden
Pages: 129-138
Published online on: 01 January 2007

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Article

RALBP1/RLIP76 mediates multidrug resistance

Kenneth J. Drake, Jyotsana Singhal, Sushma Yadav, Aalok Nadkar, Chirag Pungaliya, Sharad S. Singhal, Sanjay Awasthi
Pages: 139-144
Published online on: 01 January 2007

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Article

Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry

Jianbo He, Jeffrey Gornbein, Dejun Shen, Ming Lu, Leonor E. Rovai, Hungyi Shau, John Katz, Julian P. Whitelegge, Kym F. Faull, Helena R. Chang
Pages: 145-154
Published online on: 01 January 2007

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Article

Molecular identification, expression and prognostic role of estrogen- and progesterone receptors in head and neck cancer

J. Lukits, É. Remenár, E. Rásó, A. Ladányi, M. Kásler, J. Tímár
Pages: 155-160
Published online on: 01 January 2007

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Article

Effects of Agelas oroides and Petrosia ficiformis crude extracts on human neuroblastoma cell survival

Cristina Ferretti, Barbara Marengo, Chiara De Ciucis, Mariapaola Nitti, Maria Adelaide Pronzato, Umberto Maria Marinari, Roberto Pronzato, Renata Manconi, Cinzia Domenicotti
Pages: 161-169
Published online on: 01 January 2007

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Article

Prognostic significance of EpCAM expression in human esophageal cancer

Hitoshi Kimura, Hiroyuki Kato, Ahmad Faried, Makoto Sohda, Masanobu Nakajima, Yasuyuki Fukai, Tatsuya Miyazaki, Norihiro Masuda, Minoru Fukuchi, Hiroyuki Kuwano
Pages: 171-179
Published online on: 01 January 2007

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Article

UV light blocks EGFR signalling in human cancer cell lines

B. B. Olsen, M. T. Neves-Petersen, S. Klitgaard, O. G. Issinger, S. B. Petersen
Pages: 181-185
Published online on: 01 January 2007

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Article

Dexamethasone inhibits paclitaxel-induced cytotoxic activity through retinoblastoma protein dephosphorylation in non-small cell lung cancer cells

Masato Morita, Hisashi Suyama, Tadashi Igishi, Yasushi Shigeoka, Masahiro Kodani, Kiyoshi Hashimoto, Kenichi Takeda, Takashi Sumikawa, Eiji Shimizu
Pages: 187-192
Published online on: 01 January 2007

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Article

Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro

Claudio Festuccia, Paola Muzi, Giovanni Luca Gravina, Danilo Millimaggi, Silvia Speca, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Pages: 193-200
Published online on: 01 January 2007

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Article

Stronger growth-inhibitory effect of interferon (IFN)-β compared to IFN-α is mediated by IFN signaling pathway in hepatocellular carcinoma cells

Bazarragchaa Damdinsuren, Hiroaki Nagano, Hiroshi Wada, Motoi Kondo, Hideo Ota, Masato Nakamura, Takehiro Noda, Javzandulam Natsag, Hirofumi Yamamoto, Yuichiro Doki, Koji Umeshita, Keizo Dono, Shoji Nakamori, Masato Sakon, Morito Monden
Pages: 201-208
Published online on: 01 January 2007

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Article

Gene dosage and mutational analyses of EGFR in oligodendrogliomas

Carmen Franco-Hernandez, Victor Martinez-Glez, M. Eva Alonso, Jose M. De Campos, Alberto Isla, Jesus Vaquero, Manuel Gutierrez, Juan A. Rey
Pages: 209-215
Published online on: 01 January 2007

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Article

Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2 Corrigendum in /10.3892/ijo.2016.3487

Loredana Moro, Arnaldo A. Arbini, Ersilia Marra, Margherita Greco
Pages: 217-224
Published online on: 01 January 2007

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Article

Combination of non-viral connexin 43 gene therapy and docetaxel inhibits the growth of human prostate cancer in mice

Masayoshi Fukushima, Yoshiyuki Hattori, Takashi Yoshizawa, Yoshie Maitani
Pages: 225-231
Published online on: 01 January 2007

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Review

Apigenin and cancer chemoprevention: Progress, potential and promise (Review)

Deendayal Patel, Sanjeev Shukla, Sanjay Gupta
Pages: 233-245
Published online on: 01 January 2007

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Review

Notch signaling in gastrointestinal tract (Review)

Masuko Katoh, Masaru Katoh
Pages: 247-251
Published online on: 01 January 2007

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Article

Genetic and epigenetic changes induced by chronic low dose exposure to arsenic of mouse testicular Leydig cells

Kamaleshwar P. Singh, James W. DuMond
Pages: 253-260
Published online on: 01 January 2007

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Article

Gonadotropin-releasing hormone agonists reduce the migratory and the invasive behavior of androgen-independent prostate cancer cells by interfering with the activity of IGF-I

Marina Montagnani Marelli, Roberta M. Moretti, Stefania Mai, Patrizia Procacci, Patrizia Limonta
Pages: 261-271
Published online on: 01 January 2007

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Article

In vitro apoptotic induction of human glioblastoma cells by Fas ligand plus etoposide and in vivo antitumour activity of combined drugs in xenografted nude rats

Stéphanie Giraud, Barbara Bessette, Caroline Boda, Fabrice Lalloué, Daniel Petit, Muriel Mathonnet, Marie-Odile Jauberteau
Pages: 273-281
Published online on: 01 January 2007

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Article

Sufasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas

Pierre A. Robe, Minh-Tuan Nguyen-Khac, Frederic Lambert, Chantal Lechanteur, Olivier Jolois, Patricia Ernst-Gengoux, Bernard Rogister, Vincent Bours
Pages: 283-290
Published online on: 01 January 2007

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Article

Inhibition of cyclooxygenase-2 and telomerase activities in human leukemia cells by dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp.

Cheol Park, Jee H. Jung, Nam Deuk Kim, Yung Hyun Choi
Pages: 291-298
Published online on: 01 January 2007

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Resistance to covalent Bruton's tyrosine kinase inhibitors in diffuse large B‑cell lymphoma: Molecular mechanisms and therapeutic implications (Review)

Chuanyang Lu, Tingting Zhou, Wenxin Zhang, Lulu Wei, Qiuni Chen, Yuye Shi, Chunling Wang, Liang Yu
Article Number: 134
Published online on: 09 October 2026

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Comprehensive landscape and future perspectives of PIWI‑interacting RNAs in cancer (Review)

Xiaoqian Yu, Changlong Li, Tongtao Zhuang, Siqing Sun, Xiaoyun He, Zhenyu Ou, Nannan Li, Chunlin Ou
Article Number: 133
Published online on: 09 October 2026

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Nucleocytoplasmic transport in gynaecological cancer: From mechanisms to therapeutic potential (Review)

Ieva Norkaityte, Laura Marija Racyte, Egle Balciunaite, Aiste Avizaite, Egle Zalyte
Article Number: 132
Published online on: 08 October 2026

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cGAS‑STING pathway in digestive tract cancer: From molecular mechanisms to therapeutic applications (Review)

Tangna Chen, Jingyi Zhang, Jinghan Sun, Hongyan Zhang, Deqiang Huang, Haifeng Ye
Article Number: 131
Published online on: 07 October 2026

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Regulatory T cells in lung adenocarcinoma: Mechanisms of immune escape, prognostic significance and therapeutic opportunities (Review)

Lijuan Wang, Chenjin Ruan
Article Number: 130
Published online on: 06 October 2026

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Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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Journal Cover
December-2026 Volume 69 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Metabolic‑epigenetic coupling via lysine lactylation drives cancer stemness and multidrug resistance (Review)

Ying Yang, Nan Zhang, Dan Wang, Dongmei Ye, Yun Zhang, Xiaoju Li
Article Number: 142
Published online on: 09 November 2026

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Correction Open Access

[Corrigendum] ETS‑1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer

Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang
Article Number: 141
Published online on: 02 November 2026

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Article Open Access

PLD2 fuels 5‑fluorouracil resistance in colorectal cancer: Hypoxic hijacking of autophagy unveils a novel therapeutic vulnerability

Kunli Du, Pengfei Wang, Xisheng Yang, Yanjun Lu, Yi Wang, Wenda Wang, Jianyong Zheng, Maoxi Liu
Article Number: 140
Published online on: 02 November 2026

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Review

Pyroptosis in cancer nanotherapy: Molecular mechanisms and advanced nanosystems (Review)

Wesam H. Abdulaal, Nada H. Aljarba, Bonglee Kim, Islam M. Saadeldin, Faris Q. Alenzi, Altaf A. Abdulkhaliq, Johra Khan, Anwar Borai, Jaakko Tuomilehto, E Lin, Amir Ajoolabady, Ahmed Al‑Qahtani, Jun Ren
Article Number: 139
Published online on: 30 October 2026

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Correction Open Access

[Corrigendum] Monoamine carboxylate transporters are involved in BI-1-associated cancer metastasis in HT1080 colon fibrosarcoma cells

Geum-Hwa Lee, Han-Jung Chae, Hyung-Ryong Kim
Article Number: 138
Published online on: 19 October 2026

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Article Open Access

Disporum cantoniense suppresses non‑small cell lung cancer through AMPK/mTOR/ULK1‑mediated autophagy‑dependent apoptosis

Chi Feng, Yujiao Ji, Renqiang Chen, Qiuxu Chen, Yiru Pan, Jianming Wu, Dalian Qin, Betty Yuen Kwan Law, Vincent Kam Wai Wong, Xiaogang Zhou, Jianxin Liu, Anguo Wu
Article Number: 137
Published online on: 15 October 2026

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Review Open Access

Research progress of SPP1 in cancer regulation: Tumorigenesis, metastasis, tumor microenvironment, immunity and therapeutic targets (Review)

Yujun Xia, Dong Han, Song Tang, Huimin Yang, Rongjie Zhao, Beibei Cao, Peixi Zhu, Aiqin Shi, Huacheng Luo
Article Number: 136
Published online on: 14 October 2026

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Correction Open Access

[Corrigendum] Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER‑inhibitors is accompanied by increased sensitivity to STAT3 inhibition

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, David Mackintosh, Flavio Solca, Helmout Modjtahedi
Article Number: 135
Published online on: 09 October 2026

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