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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2007 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The NO TRAIL to YES TRAIL in cancer therapy (Review)

Ji Yeun Lee, Sara Huerta-Yepez, Mario Vega, Stavroula Baritaki, Demetrios A. Spandidos, Benjamin Bonavida
Pages: 685-691
Published online on: 01 October 2007

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Article

Expression of connective tissue growth factor in pancreatic cancer cell lines

Sungwon Kwon, Xander Munroe, Suzanne C. Crawley, Hwa Young Lee, Suzanne Spong, Douglass Bradham, James R. Gum, Marvin H. Sleisenger, Young S. Kim
Pages: 693-703
Published online on: 01 October 2007

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Article

Epigallocatechin-3 gallate induces growth inhibition and apoptosis in human breast cancer cells through survivin suppression

Yan Tang, Daniel Y. Zhao, Steven Elliott, Weiqiang Zhao, Tyler J. Curiel, Barbara S. Beckman, Matthew E. Burow
Pages: 705-711
Published online on: 01 October 2007

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Article

Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes

Kouji Banno, Megumi Yanokura, Makiko Kawaguchi, Yoshiko Kuwabara, Jyunko Akiyoshi, Yusuke Kobayashi, Takashi Iwata, Akira Hirasawa, Takuma Fujii, Nobuyuki Susumu, Kastumi Tsukazaki, Daisuke Aoki
Pages: 713-720
Published online on: 01 October 2007

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Article

Expression and roles of keratinocyte growth factor and its receptor in esophageal cancer cells

Masanori Yoshino, Toshiyuki Ishiwata, Masanori Watanabe, Tetsuro Matsunobu, Osamu Komine, Yuri Ono, Tetsushi Yamamoto, Takenori Fujii, Koshi Matsumoto, Akira Tokunaga, Zenya Naito
Pages: 721-728
Published online on: 01 October 2007

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Article

Characteristics of dimeric (bis) bidentate selective high affinity ligands as HLA-DR10 beta antibody mimics targeting non-Hodgkin's lymphoma

Gerald L. DeNardo, Saphon Hok, Arutselvan Natarajan, Monique Cosman, Sally J. DeNardo, Felice C. Lightstone, Gary R. Mirick, Aina Yuan, Julie Perkins, Vladimir V. Sysko, Joerg Lehmann, Rodney L. Balhorn
Pages: 729-740
Published online on: 01 October 2007

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Article

Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/γcnull (NOG) mice

Hiroshi Suemizu, Makoto Monnai, Yasuyuki Ohnishi, Mamoru Ito, Norikazu Tamaoki, Masato Nakamura
Pages: 741-751
Published online on: 01 October 2007

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Article

Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy

Keishi Fujiwara, Eiji Iwado, Gordon B. Mills, Raymond Sawaya, Seiji Kondo, Yasuko Kondo
Pages: 753-760
Published online on: 01 October 2007

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Article

Cepharanthin-enhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-κB activity in human oral squamous cell carcinoma cells

Tetsuya Tamatani, Masayuki Azuma, Katsumi Motegi, Natsumi Takamaru, Yuichiro Kawashima, Takashi Bando
Pages: 761-768
Published online on: 01 October 2007

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Pharmacological blockade of Fatty Acid Synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin™) by transcriptionally inhibiting ‘HER2 super-expression’ occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells

Alejandro Vazquez-Martin, Ramon Colomer, Joan Brunet, Javier A. Menendez
Pages: 769-776
Published online on: 01 October 2007

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Article

Re-activation of the p53 pathway inhibits in vivo and in vitro growth of hormone-dependent human breast cancer cells

Yayun Liang, Cynthia Besch-Williford, Indira Benakanakere, Salman M. Hyder
Pages: 777-784
Published online on: 01 October 2007

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Article

Expression and enzymatic activity of dipeptidyl peptidase-IV in human astrocytic tumours are associated with tumour grade

Jarmila Stremenova, Evzen Krepela, Vladislav Mares, Julie Trim, Vladimir Dbaly, Josef Marek, Zdislava Vanickova, Vera Lisa, Chris Yea, Aleksi Sedo
Pages: 785-792
Published online on: 01 October 2007

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Article

Low level STK15 amplification in histologically benign urothelium of patients with bladder cancer adversely predicts patient outcome following cystectomy

Stefan Denzinger, Robert Stoehr, Stephan Schwarz, Nicole Eichenseher, Gero Brockhoff, Ellen C. Obermann, Ruth Knuechel, Hagen Blaszyk, Arndt Hartmann, Peter J. Wild
Pages: 793-802
Published online on: 01 October 2007

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Article

The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells

Tomoyuki Nakamura, Kazuhiro Tanaka, Tomoya Matsunobu, Takamitsu Okada, Fumihiko Nakatani, Riku Sakimura, Masuo Hanada, Yukihide Iwamoto
Pages: 803-811
Published online on: 01 October 2007

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Article

Experimental treatment of ovarian cancers by adenovirus vectors combining receptor targeting and selective expression of tumor necrosis factor

Selva R. Murugesan, Masaki Akiyama, David A. Einfeld, Thomas J. Wickham, C. Richter King
Pages: 813-822
Published online on: 01 October 2007

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Article

Epithelial mesenchymal transition during the neoplastic transformation of human breast epithelial cells by estrogen

Daniel G. Tiezzi, Sandra V. Fernandez, Jose Russo
Pages: 823-827
Published online on: 01 October 2007

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Article

MM-1 facilitates degradation of c-Myc by recruiting proteasome and a novel ubiquitin E3 ligase

Yumiko Kimura, Arisa Nagao, Yuko Fujioka, Akiko Satou, Takahiro Taira, Sanae M.M. Iguchi-Ariga, Hiroyoshi Ariga
Pages: 829-836
Published online on: 01 October 2007

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Article

Strain-specific homeostatic responses during early stages of Azoxymethane-induced colon tumorigenesis in mice

Kishore Guda, Jillian N. Marino, Yonghwon Jung, Ken Crary, Mei Dong, Daniel W. Rosenberg
Pages: 837-842
Published online on: 01 October 2007

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Article

Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma

George Pan, Eun-Young Ahn, Yabing Chen, Gong Feng, Vishnu Reddy, Nirag C. Jhala, Jay M. McDonald
Pages: 843-850
Published online on: 01 October 2007

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Article

Ebp1-mediated inhibition of cell growth requires serine 363 phosphorylation

Damilola Akinmade, Myounghee Lee, Yuexing Zhang, Anne W. Hamburger
Pages: 851-858
Published online on: 01 October 2007

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Article

Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer

Hye Seung Lee, Gheeyoung Choe, Kyoung Un Park, Do Joong Park, Han-Kwang Yang, Byung Lan Lee, Woo Ho Kim
Pages: 859-866
Published online on: 01 October 2007

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Article

Bcl-2 overexpression sensitizes MCF-7 cells to genistein by multiple mechanisms

Chaitali Tophkhane, Shihe Yang, Wesley Bales, Linda Archer, Adeboye Osunkoya, Ann D. Thor, Xiaohe Yang
Pages: 867-874
Published online on: 01 October 2007

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Article

Upregulation of IGF-2 and IGF-1 receptor expression in oral cancer cell lines

Garrett Brady, St John Crean, Prashant Naik, Supriya Kapas
Pages: 875-881
Published online on: 01 October 2007

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Article

Study of the phenotypic relationship in the IMR-32 human neuroblastoma cell line by Sedimentation Field Flow Fractionation

G. Bégaud-Grimaud, S. Battu, P. Lazcoz, J. S. Castresana, M. O. Jauberteau, P. J.P. Cardot
Pages: 883-892
Published online on: 01 October 2007

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Article

The receptor tyrosine kinase Tie1 is expressed and activated in epithelial tumour cell lines

Kathryn A. Rees, Harprit Singh, Nicholas P.J. Brindle
Pages: 893-897
Published online on: 01 October 2007

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Article

Predictive implications of nucleoside metabolizing enzymes in premenopausal women with node-positive primary breast cancer who were randomly assigned to receive tamoxifen alone or tamoxifen plus tegafur-uracil as adjuvant therapy

Masakazu Toi, Tadashi Ikeda, Futoshi Akiyama, Masafumi Kurosumi, Hitoshi Tsuda, Goi Sakamoto, Osahiko Abe
Pages: 899-906
Published online on: 01 October 2007

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Comparative evaluation of C1311 cytotoxic activity and interference with cell cycle progression in a panel of human solid tumour and leukaemia cell lines

Cinzia De Marco, Nadia Zaffaroni, Elizabeth Comijn, Anna Tesei, Wainer Zoli, Godefriedus J. Peters
Pages: 907-913
Published online on: 01 October 2007

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Article

The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line

Taka-aki Matsui, Yoshihiro Sowa, Hiroaki Murata, Koichi Takagi, Ryoko Nakanishi, Shunji Aoki, Masayuki Yoshikawa, Motomasa Kobayashi, Tomoya Sakabe, Toshikazu Kubo, Toshiyuki Sakai
Pages: 915-922
Published online on: 01 October 2007

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Article

Cobalt chloride induces apoptosis and zinc chloride suppresses cobalt-induced apoptosis by Bcl-2 expression in human submandibular gland HSG cells

Kazumi Akita, Hirohiko Okamura, Kaya Yoshida, Hiroyuki Morimoto, Hiroaki Ogawa-Iyehara, Tatsuji Haneji
Pages: 923-929
Published online on: 01 October 2007

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Article

Benefits of gene transduction of granulocyte macrophage colony-stimulating factor in cancer vaccine using genetically modified dendritic cells

Toshiyasu Ojima, Makoto Iwahashi, Masaki Nakamura, Kenji Matsuda, Mikihito Nakamori, Kentaro Ueda, Teiji Naka, Masahiro Katsuda, Motoki Miyazawa, Hiroki Yamaue
Pages: 931-939
Published online on: 01 October 2007

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Article

Differential expression of acidic proteins with progression in the MCF10 model of human breast disease

Nathan S. Buchanan, Jia Zhao, Kan Zhu, Tasneem H. Patwa, Fred R. Miller, David M. Lubman
Pages: 941-949
Published online on: 01 October 2007

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Article

Design, construction, and in vitro analysis of A33scFv::CDy, a recombinant fusion protein for antibody-directed enzyme prodrug therapy in colon cancer

Vânia Coelho, Jens Dernedde, Ulf Petrausch, Hossein Panjideh, Hendrik Fuchs, Christoph Menzel, Stefan Dübel, Ulrich Keilholz, Eckhard Thiel, P. Markus Deckert
Pages: 951-957
Published online on: 01 October 2007

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Article

Androgen receptor-dependent and -independent mechanisms mediate Ganoderma lucidum activities in LNCaP prostate cancer cells

Ben-Zion Zaidman, Solomon P. Wasser, Eviatar Nevo, Jamal Mahajna
Pages: 959-967
Published online on: 01 October 2007

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Article

Inhibition of lymphocyte function associated antigen 1 by LFA878 induces apoptosis in multiple myeloma cells and is associated with downregulation of the focal adhesion kinase/phosphatidylinositol 3 kinase/Akt pathway

Ralf Schmidmaier, Sonja Mandl-Weber, Leander Gaul, Philipp Baumann, Irmgard Bumeder, Christian Straka, Bertold Emmerich
Pages: 969-976
Published online on: 01 October 2007

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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