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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2008 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Balanitin-6 and -7: Diosgenyl saponins isolated from Balanites aegyptiaca Del. display significant anti-tumor activity in vitro and in vivo

Charlemagne Gnoula, Véronique Mégalizzi, Nancy De Nève, Sébastien Sauvage, Fabrice Ribaucour, Pierre Guissou, Pierre Duez, Jacques Dubois, Laurent Ingrassia, Florence Lefranc, Robert Kiss, Tatjana Mijatovic
Pages: 5-15
Published online on: 01 January 2008

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Article

Apoptotic genes as potential markers of metastatic phenotype in human osteosarcoma cell lines

Cinzia Zucchini, Anna Rocchi, Maria Cristina Manara, Paola De Sanctis, Cristina Capanni, Michele Bianchini, Paolo Carinci, Katia Scotlandi, Luisa Valvassori
Pages: 17-31
Published online on: 01 January 2008

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Article

aP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice

Frederik Van Dyck, Ilse Scroyen, Jeroen Declercq, Raf Sciot, Barbara Kahn, Roger Lijnen, Wim J.M. Van de Ven
Pages: 33-40
Published online on: 01 January 2008

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Article

Vascular endothelial growth factor is an autocrine survival factor for breast tumour cells under hypoxia

Martin P. Barr, David J. Bouchier-Hayes, Judith J. Harmey
Pages: 41-48
Published online on: 01 January 2008

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Article

PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: A mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment

Samuel Guénin, Laurent Schwartz, Daniel Morvan, Jean Marc Steyaert, Amandine Poignet, Jean Claude Madelmont, Aicha Demidem
Pages: 49-57
Published online on: 01 January 2008

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Article

A new subtype-specific monoclonal antibody for IAP-survivin identifies high-risk patients with diffuse large B-cell lymphoma and improves the prognostic value of bcl-2

Tryfonia Mainou-Fowler, Lynn Marie Overman, Helen Dignum, Katrina Wood, Stephen Crosier, Brian Angus, Stephen John Proctor, John J. Anderson
Pages: 59-68
Published online on: 01 January 2008

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Article

Measurement of hypoxia using invasive oxygen-sensitive electrode, pimonidazole binding and 18F-FDG uptake in anaemic or erythropoietin-treated mice bearing human glioma xenografts

Sonia Scigliano, Sophie Pinel, Sylvain Poussier, Fanny Fouyssac, Francois Plenat, Gilles Karcher, Pascal Chastagner
Pages: 69-77
Published online on: 01 January 2008

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Article

Mechanism of cell death induced by spermine and amine oxidase in mouse melanoma cells

Diana A. Averill-Bates, Qixiang Ke, André Tanel, Julie Roy, Guy Fortier, Enzo Agostinelli
Pages: 79-88
Published online on: 01 January 2008

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Article

Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin

Sun Young Kim, Hwang Phill Kim, Yu Jung Kim, Do Youn Oh, Seock-Ah Im, Dongsoon Lee, Hyun-Soon Jong, Tae-You Kim, Yung-Jue Bang
Pages: 89-95
Published online on: 01 January 2008

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Article

The novel phenylester anticancer compounds: Study of a derivative of aspirin (phoshoaspirin)

Basil Rigas, Vasiliki Kozoni
Pages: 97-100
Published online on: 01 January 2008

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Article

Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas

Avaniyapuram Kannan Murugan, Nguyen Thi Hong, Yasuhisa Fukui, Arasambattu Kannan Munirajan, Nobuo Tsuchida
Pages: 101-111
Published online on: 01 January 2008

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Article

Sequence-dependent synergism and antagonism between paclitaxel and gemcitabine in breast cancer cells: The importance of scheduling

Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Ramon Colomer, Rafael De Llorens, Joan Brunet, Javier A. Menendez
Pages: 113-120
Published online on: 01 January 2008

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Article

GSH loss per se does not affect neuroblastoma survival and is not genotoxic

Barbara Marengo, Emanuela Balbis, Stefania Patriarca, Chiara De Ciucis, Annalisa Furfaro, Mariapaola Nitti, Umberto Maria Marinari, Maria Adelaide Pronzato, Nicola Traverso, Cinzia Domenicotti
Pages: 121-127
Published online on: 01 January 2008

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Article

Positive expressions of N-acetylglucosaminyltransferase-V (GnT-V) and β1-6 branching N-linked oligosaccharides in human testicular germ cells diminish during malignant transformation and progression

Atsushi Kyan, Noritaka Kamimura, Shigeru Hagisawa, Shingo Hatakeyama, Takuya Koie, Takahiro Yoneyama, Yoichi Arai, Hiroaki Nakagawa, Shin-Ichiro Nishimura, Eiji Miyoshi, Yasuhiro Hashimoto, Chikara Ohyama
Pages: 129-134
Published online on: 01 January 2008

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Article

Bap29varP, a variant of Bap29, influences the cell surface expression of the human P-glycoprotein

Prema S. Rao, Ulrich Bickel, Kalkunte S. Srivenugopal, U. Subrahmanyeswara Rao
Pages: 135-144
Published online on: 01 January 2008

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Article

The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma

Yasuo Miyazaki, Akira Hara, Keizo Kato, Takeru Oyama, Yasuhiro Yamada, Hideki Mori, Toshiyuki Shibata
Pages: 145-151
Published online on: 01 January 2008

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Article

Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rγnull (NOG) mice

Kenji Hamada, Makoto Monnai, Kenji Kawai, Chiyoko Nishime, Chika Kito, Noriyuki Miyazaki, Yasuyuki Ohnishi, Masato Nakamura, Hiroshi Suemizu
Pages: 153-159
Published online on: 01 January 2008

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Article

Role of alternative splicing of periostin in human bladder carcinogenesis

Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Tokuhiro Chano, Hidetoshi Okabe, Yusaku Okada, Hirokazu Inoue
Pages: 161-169
Published online on: 01 January 2008

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Article

Topotecan and small interfering RNA suppress survivin expression synergistically in Caki-1 renal cancer cells: Direct suppression of survivin and enhancement of transfection efficiency by topotecan

Akinori Sato, Keiichi Ito, Takako Asano, Makoto Sumitomo, Tomohiko Asano, Masamichi Hayakawa
Pages: 171-176
Published online on: 01 January 2008

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Article

Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects Expression of Concern in /10.3892/ijo.2026.5896

D. Carlisi, B. Vassallo, M. Lauricella, S. Emanuele, A. D'Anneo, E. Di Leonardo, P. Di Fazio, R. Vento, G. Tesoriere
Pages: 177-184
Published online on: 01 January 2008

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Article

suPAR, a soluble form of urokinase plasminogen activator receptor, inhibits human prostate cancer cell growth and invasion

M. Piccolella, C. Festuccia, D. Millimaggi, A. Locatelli, M. Bologna, M. Motta, D. Dondi
Pages: 185-191
Published online on: 01 January 2008

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Article

Different tumoricidal effects of interferon subclasses and p53 status on hepatocellular carcinoma development and neovascularization

Ryuichi Noguchi, Hitoshi Yoshiji, Yasuhide Ikenaka, Mitsuteru Kitade, Kosuke Kaji, Junichi Yoshi, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Takemi Akahane, Masahito Uemura, Hiroshi Fukui
Pages: 193-199
Published online on: 01 January 2008

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Article

Thymidylate synthase polymorphisms and mRNA expression are independent chemotherapy predictive markers in esophageal adenocarcinoma patients

Hidekazu Kuramochi, Koji Tanaka, Daniel Oh, Bethany J. Lehman, Christy M. Dunst, Dong Yun Yang, Steven R. De Meester, Jeffery A. Hagen, Kathleen D. Danenberg, Tom R. De Meester, Peter V. Danenberg
Pages: 201-208
Published online on: 01 January 2008

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Article

Ethanolic extracts of herbal supplement Equiguard™ suppress growth and control gene expression in CWR22Rv1 cells representing the transition of prostate cancer from androgen dependence to hormone refractory status

Tze-Chen Hsieh, Joseph M. Wu
Pages: 209-219
Published online on: 01 January 2008

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Article

The oncofetal protein, 5T4, is a suitable target for antibody-guided anti-cancer chemotherapy with calicheamicin

E. R. Boghaert, L. Sridharan, K. M. Khandke, D. Armellino, M. G. Ryan, K. Myers, R. Harrop, A. Kunz, P. R. Hamann, K. Marquette, M. Dougher, J. F. DiJoseph, N. K. Damle
Pages: 221-234
Published online on: 01 January 2008

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Article

Keratoepithelin reverts the suppression of tissue factor pathway inhibitor 2 by MYCN in human neuroblastoma: A mechanism to inhibit invasion

Juergen Becker, Sonja Volland, Ievgeniia Noskova, Alexander Schramm, Lothar L. Schweigerer, Joerg Wilting
Pages: 235-240
Published online on: 01 January 2008

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Article

Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma

Mohsen Shadidi, Dag Sørensen, Anne Dybwad, Gro Furset, Mouldy Sioud
Pages: 241-247
Published online on: 01 January 2008

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Article

Ciglitazone, an agonist of peroxisome proliferator-activated receptor γ, exerts potentiated cytostatic/cytotoxic effects against tumor cells when combined with lovastatin

Piotr Mrówka, Eliza Glodkowska, Dominika Nowis, Magdalena Legat, Tadeusz Issat, Marcin Makowski, Angelika Szokalska, Sylwia Janowska, Tomasz Stoklosa, Marek Jakóbisiak, Jakub Golab
Pages: 249-255
Published online on: 01 January 2008

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Article

Inhibition of NF-κB by (E)3-[(4-methylphenyl)-sulfonyl]-2-propenenitrile (BAY11-7082; BAY) is associated with enhanced 12-O-tetradecanoylphorbol-13-acetate-induced growth suppression and apoptosis in human prostate cancer PC-3 cells

Xi Zheng, Richard L. Chang, Xiao-Xing Cui, Gina Avila, Mou-Tuan Huang, Yue Liu, Ah Ng Tony Kong, Arnold B. Rabson, Allan H. Conney
Pages: 257-264
Published online on: 01 January 2008

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Article

Live cell vaccines expressing B7.1, monocyte chemoattractant protein 1 and granulocyte-macrophage colony stimulation factor derived from mouse HPV16-transformed cells

Monika Lakatosová-Andelová, Pavel Jinoch, Martina Dusková, Iuri Marinov, Vladimír Vonka
Pages: 265-271
Published online on: 01 January 2008

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Article

Characterisation of a novel matrix metalloproteinase inhibitor on pancreatic adenocarcinoma cells in vitro and in an orthotopic pancreatic cancer model in vivo

Matthias Kapischke, Tim Fischer, Katrin Tiessen, Harald Tschesche, Hans-Peter Bruch, Holger Kalthoff, Marie-Luise Kruse
Pages: 273-282
Published online on: 01 January 2008

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Journal Cover
June-2026 Volume 68 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Biomarkers for oesophageal squamous cell carcinoma and the role of HPV: Multi‑omics approaches and current evidence (Review)

Limin Zou, Hongzhou Zhao, Jiaying Zhang, Jialing Xie, Xiaolu An, Xianhua Qi, Yuting Yue, Lijia Zhang, Xiajun Zhang, Kuancan Liu
Article Number: 74
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] MicroRNA‑155 promotes tumor growth of human hepatocellular carcinoma by targeting ARID2

Li Zhang, Wei Wang, Xiaobin Li, Sai He, Jianfeng Yao, Xiaolong Wang, Di Zhang, Xuejun Sun
Article Number: 73
Published online on: 22 April 2026

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Review Open Access

Research advances in aptamers in the diagnosis and treatment of breast cancer (Review)

Liqiang Chu, Yunfeng Xiao, Xinhua Li, Jiawei Cui, Luyao Ma, Bin Shao, Hongwei Cui
Article Number: 72
Published online on: 21 April 2026

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Review Open Access

METTL3 in esophageal cancer: Current insights into molecular mechanisms, subtype heterogeneity and targeted therapy prospects (Review)

Chunlan Pu, Huan Hu, Hengrui Fan, Tao Chen, Jiao Tang
Article Number: 71
Published online on: 21 April 2026

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Expression of Concern Open Access

[Expression of Concern] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 70
Published online on: 15 April 2026

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Review Open Access

Novel therapeutic strategies for metastatic castration‑resistant prostate cancer: Beyond androgen receptor pathway inhibition (Review)

Yaqin Wang, Yongqiang Xie, Qiang Zhao
Article Number: 69
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] PRIMA‑1 inhibits growth of breast cancer cells by re‑activating mutant p53 protein

Yayun Liang, Cynthia Besch-Williford, Salman M. Hyder
Article Number: 68
Published online on: 06 April 2026

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Article Open Access

RRP9 suppresses hepatocellular carcinoma progression by inhibiting the PI3K/AKT/mTOR pathway

Zhengkang Fu, Man Li, Keshuai Dong, Jiarui Feng, Weixing Wang
Article Number: 67
Published online on: 06 April 2026

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Retraction Open Access

[Retracted] Antitumor activity of NRC‑AN‑019 in a pre‑clinical breast cancer model

Christopher S. Gondi, Bharathi Gorantla, A.K.S. Bhujanga Rao, K. Amala, M.U.R. Naidu, K.V. Jogi, G. Venkat Ramana, Praveen C. Myneni, Ajit Junnarkar, Jasti S. Rao
Article Number: 66
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 69 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Expression of Concern Open Access

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects

D. Carlisi, B. Vassallo, M. Lauricella, S.  Emanuele, A. D'anneo, E. Di Leonardo, P. Di Fazio, R.  Vento, G.  Tesoriere
Article Number: 83
Published online on: 20 May 2026

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Article Open Access

Integrin beta 4 promotes colorectal cancer progression by upregulating Ezrin and activating the Wnt/β‑catenin signaling pathway

Jing Wang, Yi Si, Mingda Xuan, Shuangshuang Han, Kunyi Liu, Jiao Jiao, Xiaoyan Men, Hongfei Li, Jia Wang, Ting Liu, Weifang Yu
Article Number: 82
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells

Pin-Hao Ko, Govinda Lenka, Yu-An Chen, Eric Y. Chuang, Mong-Hsun Tsai, Yuh-Pyng Sher, Liang-Chuan Lai
Article Number: 81
Published online on: 18 May 2026

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Review Open Access

snoRNAs and their derived sdRNAs: Emerging regulators, biomarkers, and therapeutic targets in human cancers (Review)

Jiahui Mao, Hao Lin, Feng Gu, Zhaoji Pan
Article Number: 80
Published online on: 15 May 2026

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Review Open Access

Deubiquitinating enzymes in cervical cancer: Molecular mechanisms and therapeutic implications (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 79
Published online on: 14 May 2026

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Article Open Access

BMP4 derived from human gastrointestinal carcinoma cells impairs myogenic differentiation: A possible in vitro mechanism of cancer‑induced cachexia

Kazuki Higure, Yoshihiko Kitajima, Naoya Kimura, Shota Ikeda, Shohei Matsufuji, Tomokazu Tanaka, Hirokazu Noshiro
Article Number: 78
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Radiation‑inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Venkateswara Rao Gogineni, Arun Kumar Nalla, Reshu Gupta, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Article Number: 77
Published online on: 11 May 2026

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Review Open Access

Circulating proteins as biomarkers of response to cancer immunotherapy (Review)

Celeste Pinard, Angeline Ginzac, Catherine Abrial, Xavier Durando, Nina Radosevic‑Robin
Article Number: 76
Published online on: 06 May 2026

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Correction Open Access

[Corrigendum] Tumor necrosis factor‑α triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial‑ and non‑mitochondrial‑dependent pathways

Denis Selimovic, Renate   U. Wahl, Emmanuelle Ruiz, Rizwan Aslam, Thomas   W. Flanagan, Sofie-Yasmin Hassan, Simeon Santourlidis, Youssef Haikel, Paul Friedlander, Mosaad Megahed, Emad Kandil, Mohamed Hassan
Article Number: 75
Published online on: 27 April 2026

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