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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2008 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Histone deacetylase inhibitors: Apoptotic effects and clinical implications (Review)

Sonia Emanuele, Marianna Lauricella, Giovanni Tesoriere
Pages: 637-646
Published online on: 01 October 2008

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Article

Growth inhibitory effects of pegylated IFN-α2b and 5-fluorouracil in combination on renal cell carcinoma cell lines in vitro and in vivo

Fukuko Moriya, Sachiko Ogasawara, Yuji Basaki, Jun Akiba, Sakiko Kojiro, Suguru Fukahori, Hironori Ishizaki, Naoyo Nishida, Kei Matsuoka, Masamichi Kojiro, Michihiko Kuwano, Hirohisa Yano
Pages: 647-655
Published online on: 01 October 2008

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Article

Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation

Aruna Basu, Subrata Haldar
Pages: 657-663
Published online on: 01 October 2008

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Article Open Access

Targeting metastatic cancer from the inside: A new generation of targeted gene delivery vectors enables personalized cancer vaccination in situ

Erlinda M. Gordon, John P. Levy, Rebecca A. Reed, W. Nina Petchpud, Liqiong Liu, Carlan B. Wendler, Frederick L. Hall
Pages: 665-675
Published online on: 01 October 2008

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Article

Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1

Rosa Drago-Ferrante, Andrea Santulli, Riccardo Di Fiore, Michela Giuliano, Giuseppe Calvaruso, Giovanni Tesoriere, Renza Vento
Pages: 677-687
Published online on: 01 October 2008

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Article

Tailor-made approach to photodynamic therapy in the treatment of cancer based on Bcl-2 photodamage

Jitsuo Usuda, Takeshi Hirata, Shuji Ichinose, Taichirou Ishizumi, Tatsuya Inoue, Keishi Ohtani, Sachio Maehara, Masae Yamada, Hidemitsu Tsutsui, Tetsuya Okunaka, Harubumi Kato, Norihiko Ikeda
Pages: 689-696
Published online on: 01 October 2008

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Article

Autocrine and/or paracrine growth of aggressive ATLL cells caused by HGF and c-Met

Y. Onimaru, K. Tsukasaki, K. Murata, Y. Imaizumi, Y. L. Choi, H. Hasegawa, K. Sugahara, Y. Yamada, T. Hayashi, M. Nakashima, T. Taguchi, H. Mano, S. Kamihira, M. Tomonaga
Pages: 697-703
Published online on: 01 October 2008

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Article

Response of brain specific microenvironment to P-glycoprotein inhibitor: An important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors

Kyeung Min Joo, Sang Yong Song, Kwan Park, Mi Hyun Kim, Juyoun Jin, Bong Gu Kang, Mi Jung Jang, Gwan Sun Lee, Maeng Sup Kim, Do-Hyun Nam
Pages: 705-712
Published online on: 01 October 2008

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Article

Regulation of p63 expression in primary and immortalized nasopharyngeal epithelial cells

Y. L. Yip, S. W. Tsao
Pages: 713-724
Published online on: 01 October 2008

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Article

Glycolysis module activated by hypoxia-inducible factor 1α is related to the aggressive phenotype of hepatocellular carcinoma

Takashi Hamaguchi, Norio Iizuka, Ryouichi Tsunedomi, Yoshihiko Hamamoto, Takanobu Miyamoto, Michihisa Iida, Yoshihiro Tokuhisa, Kazuhiko Sakamoto, Motonari Takashima, Takao Tamesa, Masaaki Oka
Pages: 725-731
Published online on: 01 October 2008

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Article

The dual EGF/VEGF receptor tyrosine kinase inhibitor AEE788 inhibits growth of human hepatocellular carcinoma xenografts in nude mice

Kinya Okamoto, Daniel Neureiter, Beate Alinger, Matthias Meissnitzer, Gabriele Sass, Volker Schmitz, Pietro Di Fazio, Till Wissniowski, Susanne Gahr, Bernd Hohenstein, Bernhard Kaufmann, Axel Schlösser, Ulrike Haus, Eckhart G. Hahn, Christoph Herold, Matthias Ocker
Pages: 733-742
Published online on: 01 October 2008

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Article

p28GANK knockdown-derived reactive oxygen species induces apoptosis through mitochondrial dysfunction mediated by p38 in hepG2 cells

Xuefeng Wang, Honghai Li, Yao Chen, Jing Fu, Yibin Ren, Liwei Dong, Shanhua Tang, Shuqin Liu, Mengchao Wu, Hongyang Wang
Pages: 743-750
Published online on: 01 October 2008

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Article

Prevention and delay in progression of human squamous cell carcinoma of the head and neck in nude mice by stable overexpression of the opioid growth factor receptor

Patricia J. McLaughlin, Shawn Kreiner, Clinton R. Morgan, Ian S. Zagon
Pages: 751-757
Published online on: 01 October 2008

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Article

Glioma gene therapy with soluble transforming growth factor-β receptors II and III

Ulrike Naumann, Philipp Maass, Anne-Kathrin Gleske, Steffen Aulwurm, Michael Weller, Guenter Eisele
Pages: 759-765
Published online on: 01 October 2008

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Article

Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells

Eun Ju Lee, Bo Bin Lee, Soon-Ja Kim, Yong-Doo Park, Joobae Park, Duk-Hwan Kim
Pages: 767-776
Published online on: 01 October 2008

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Article

HIV-1 Tat enhances replicative potential of human oral keratinocytes harboring HPV-16 genome

Reuben H. Kim, Ji Min Yochim, Mo K. Kang, Ki-Hyuk Shin, Russell Christensen, No-Hee Park
Pages: 777-782
Published online on: 01 October 2008

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Article

Simultaneous downregulation of uPAR and MMP-9 induces overexpression of the FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas

Christopher S. Gondi, Dzung H. Dinh, Meena Gujrati, Jasti S. Rao
Pages: 783-790
Published online on: 01 October 2008

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Article

Clusterin: A potential target for improving response to antiestrogens

Sara Toffanin, Maria Grazia Daidone, Patrizia Miodini, Loris De Cecco, Paolo Gandellini, Vera Cappelletti
Pages: 791-798
Published online on: 01 October 2008

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Article

Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats

Chinthalapally V. Rao, Stancy Joseph, Li Gao, Jagan M.R. Patlolla, Chang-In Choi, Levy Kopelovich, Vernon E. Steele, Basil Rigas
Pages: 799-805
Published online on: 01 October 2008

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Article Open Access

Induction of cell cycle arrest and apoptosis in myeloma cells by cepharanthine, a biscoclaurine alkaloid

Yoshitaka Kikukawa, Yutaka Okuno, Hiro Tatetsu, Miki Nakamura, Naoko Harada, Shikiko Ueno, Yorinori Kamizaki, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 807-814
Published online on: 01 October 2008

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Article

MYCN downregulates integrin α1 to promote invasion of human neuroblastoma cells

Natsumi Tanaka, Masahiro Fukuzawa
Pages: 815-821
Published online on: 01 October 2008

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Article

Activation of human T cells by a tumor vaccine infected with recombinant Newcastle disease virus producing IL-2

Markus Janke, Ben Peeters, Heng Zhao, Olav de Leeuw, Rob Moorman, Annette Arnold, Yvonne Ziouta, Philippe Fournier, Volker Schirrmacher
Pages: 823-832
Published online on: 01 October 2008

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Article

Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by α-lipoic acid in human leukemia HL-60 cells

Selvakumar Elangovan, Tze-Chen Hsieh
Pages: 833-838
Published online on: 01 October 2008

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Article

Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis

Natalia Scaglia, R. Ariel Igal
Pages: 839-850
Published online on: 01 October 2008

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Article

Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and γ-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells

Tze-Chen Hsieh, Joseph M. Wu
Pages: 851-859
Published online on: 01 October 2008

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Article

Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer

Jia-Jing Lee, Janos Geli, Catharina Larsson, Göran Wallin, Mohsen Karimi, Jan Zedenius, Anders Höög, Theodoros Foukakis
Pages: 861-869
Published online on: 01 October 2008

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Article Open Access

Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair

Georgia I. Terzoudi, Satyendra Kumar Singh, Gabriel E. Pantelias, George Iliakis
Pages: 871-879
Published online on: 01 October 2008

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Article

Integrative genomic analyses on GLI2: Mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53

Yuriko Katoh, Masaru Katoh
Pages: 881-886
Published online on: 01 October 2008

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Article

Biochemical effects of piceatannol in human HL-60 promyelocytic leukemia cells - synergism with Ara-C

Monika Fritzer-Szekeres, Ivo Savinc, Zsuzsanna Horvath, Philipp Saiko, Michael Pemberger, Geraldine Graser, Astrid Bernhaus, Maria Ozsvar-Kozma, Michael Grusch, Walter Jaeger, Thomas Szekeres
Pages: 887-892
Published online on: 01 October 2008

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Article

Methylation-associated silencing of TU3A in human cancers

Yasuo Awakura, Eijiro Nakamura, Noriyuki Ito, Toshiyuki Kamoto, Osamu Ogawa
Pages: 893-899
Published online on: 01 October 2008

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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