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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2008 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Histone deacetylase inhibitors: Apoptotic effects and clinical implications (Review)

Sonia Emanuele, Marianna Lauricella, Giovanni Tesoriere
Pages: 637-646
Published online on: 01 October 2008

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Article

Growth inhibitory effects of pegylated IFN-α2b and 5-fluorouracil in combination on renal cell carcinoma cell lines in vitro and in vivo

Fukuko Moriya, Sachiko Ogasawara, Yuji Basaki, Jun Akiba, Sakiko Kojiro, Suguru Fukahori, Hironori Ishizaki, Naoyo Nishida, Kei Matsuoka, Masamichi Kojiro, Michihiko Kuwano, Hirohisa Yano
Pages: 647-655
Published online on: 01 October 2008

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Article

Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation

Aruna Basu, Subrata Haldar
Pages: 657-663
Published online on: 01 October 2008

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Article Open Access

Targeting metastatic cancer from the inside: A new generation of targeted gene delivery vectors enables personalized cancer vaccination in situ

Erlinda M. Gordon, John P. Levy, Rebecca A. Reed, W. Nina Petchpud, Liqiong Liu, Carlan B. Wendler, Frederick L. Hall
Pages: 665-675
Published online on: 01 October 2008

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Article

Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1

Rosa Drago-Ferrante, Andrea Santulli, Riccardo Di Fiore, Michela Giuliano, Giuseppe Calvaruso, Giovanni Tesoriere, Renza Vento
Pages: 677-687
Published online on: 01 October 2008

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Article

Tailor-made approach to photodynamic therapy in the treatment of cancer based on Bcl-2 photodamage

Jitsuo Usuda, Takeshi Hirata, Shuji Ichinose, Taichirou Ishizumi, Tatsuya Inoue, Keishi Ohtani, Sachio Maehara, Masae Yamada, Hidemitsu Tsutsui, Tetsuya Okunaka, Harubumi Kato, Norihiko Ikeda
Pages: 689-696
Published online on: 01 October 2008

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Article

Autocrine and/or paracrine growth of aggressive ATLL cells caused by HGF and c-Met

Y. Onimaru, K. Tsukasaki, K. Murata, Y. Imaizumi, Y. L. Choi, H. Hasegawa, K. Sugahara, Y. Yamada, T. Hayashi, M. Nakashima, T. Taguchi, H. Mano, S. Kamihira, M. Tomonaga
Pages: 697-703
Published online on: 01 October 2008

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Article

Response of brain specific microenvironment to P-glycoprotein inhibitor: An important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors

Kyeung Min Joo, Sang Yong Song, Kwan Park, Mi Hyun Kim, Juyoun Jin, Bong Gu Kang, Mi Jung Jang, Gwan Sun Lee, Maeng Sup Kim, Do-Hyun Nam
Pages: 705-712
Published online on: 01 October 2008

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Article

Regulation of p63 expression in primary and immortalized nasopharyngeal epithelial cells

Y. L. Yip, S. W. Tsao
Pages: 713-724
Published online on: 01 October 2008

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Article

Glycolysis module activated by hypoxia-inducible factor 1α is related to the aggressive phenotype of hepatocellular carcinoma

Takashi Hamaguchi, Norio Iizuka, Ryouichi Tsunedomi, Yoshihiko Hamamoto, Takanobu Miyamoto, Michihisa Iida, Yoshihiro Tokuhisa, Kazuhiko Sakamoto, Motonari Takashima, Takao Tamesa, Masaaki Oka
Pages: 725-731
Published online on: 01 October 2008

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Article

The dual EGF/VEGF receptor tyrosine kinase inhibitor AEE788 inhibits growth of human hepatocellular carcinoma xenografts in nude mice

Kinya Okamoto, Daniel Neureiter, Beate Alinger, Matthias Meissnitzer, Gabriele Sass, Volker Schmitz, Pietro Di Fazio, Till Wissniowski, Susanne Gahr, Bernd Hohenstein, Bernhard Kaufmann, Axel Schlösser, Ulrike Haus, Eckhart G. Hahn, Christoph Herold, Matthias Ocker
Pages: 733-742
Published online on: 01 October 2008

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Article

p28GANK knockdown-derived reactive oxygen species induces apoptosis through mitochondrial dysfunction mediated by p38 in hepG2 cells

Xuefeng Wang, Honghai Li, Yao Chen, Jing Fu, Yibin Ren, Liwei Dong, Shanhua Tang, Shuqin Liu, Mengchao Wu, Hongyang Wang
Pages: 743-750
Published online on: 01 October 2008

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Article

Prevention and delay in progression of human squamous cell carcinoma of the head and neck in nude mice by stable overexpression of the opioid growth factor receptor

Patricia J. McLaughlin, Shawn Kreiner, Clinton R. Morgan, Ian S. Zagon
Pages: 751-757
Published online on: 01 October 2008

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Article

Glioma gene therapy with soluble transforming growth factor-β receptors II and III

Ulrike Naumann, Philipp Maass, Anne-Kathrin Gleske, Steffen Aulwurm, Michael Weller, Guenter Eisele
Pages: 759-765
Published online on: 01 October 2008

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Article

Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells

Eun Ju Lee, Bo Bin Lee, Soon-Ja Kim, Yong-Doo Park, Joobae Park, Duk-Hwan Kim
Pages: 767-776
Published online on: 01 October 2008

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Article

HIV-1 Tat enhances replicative potential of human oral keratinocytes harboring HPV-16 genome

Reuben H. Kim, Ji Min Yochim, Mo K. Kang, Ki-Hyuk Shin, Russell Christensen, No-Hee Park
Pages: 777-782
Published online on: 01 October 2008

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Article

Simultaneous downregulation of uPAR and MMP-9 induces overexpression of the FADD-associated protein RIP and activates caspase 9-mediated apoptosis in gliomas

Christopher S. Gondi, Dzung H. Dinh, Meena Gujrati, Jasti S. Rao
Pages: 783-790
Published online on: 01 October 2008

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Article

Clusterin: A potential target for improving response to antiestrogens

Sara Toffanin, Maria Grazia Daidone, Patrizia Miodini, Loris De Cecco, Paolo Gandellini, Vera Cappelletti
Pages: 791-798
Published online on: 01 October 2008

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Article

Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats

Chinthalapally V. Rao, Stancy Joseph, Li Gao, Jagan M.R. Patlolla, Chang-In Choi, Levy Kopelovich, Vernon E. Steele, Basil Rigas
Pages: 799-805
Published online on: 01 October 2008

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Article Open Access

Induction of cell cycle arrest and apoptosis in myeloma cells by cepharanthine, a biscoclaurine alkaloid

Yoshitaka Kikukawa, Yutaka Okuno, Hiro Tatetsu, Miki Nakamura, Naoko Harada, Shikiko Ueno, Yorinori Kamizaki, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 807-814
Published online on: 01 October 2008

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Article

MYCN downregulates integrin α1 to promote invasion of human neuroblastoma cells

Natsumi Tanaka, Masahiro Fukuzawa
Pages: 815-821
Published online on: 01 October 2008

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Article

Activation of human T cells by a tumor vaccine infected with recombinant Newcastle disease virus producing IL-2

Markus Janke, Ben Peeters, Heng Zhao, Olav de Leeuw, Rob Moorman, Annette Arnold, Yvonne Ziouta, Philippe Fournier, Volker Schirrmacher
Pages: 823-832
Published online on: 01 October 2008

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Article

Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by α-lipoic acid in human leukemia HL-60 cells

Selvakumar Elangovan, Tze-Chen Hsieh
Pages: 833-838
Published online on: 01 October 2008

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Article

Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis

Natalia Scaglia, R. Ariel Igal
Pages: 839-850
Published online on: 01 October 2008

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Article

Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and γ-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells

Tze-Chen Hsieh, Joseph M. Wu
Pages: 851-859
Published online on: 01 October 2008

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Article

Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer

Jia-Jing Lee, Janos Geli, Catharina Larsson, Göran Wallin, Mohsen Karimi, Jan Zedenius, Anders Höög, Theodoros Foukakis
Pages: 861-869
Published online on: 01 October 2008

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Article Open Access

Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair

Georgia I. Terzoudi, Satyendra Kumar Singh, Gabriel E. Pantelias, George Iliakis
Pages: 871-879
Published online on: 01 October 2008

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Article

Integrative genomic analyses on GLI2: Mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53

Yuriko Katoh, Masaru Katoh
Pages: 881-886
Published online on: 01 October 2008

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Article

Biochemical effects of piceatannol in human HL-60 promyelocytic leukemia cells - synergism with Ara-C

Monika Fritzer-Szekeres, Ivo Savinc, Zsuzsanna Horvath, Philipp Saiko, Michael Pemberger, Geraldine Graser, Astrid Bernhaus, Maria Ozsvar-Kozma, Michael Grusch, Walter Jaeger, Thomas Szekeres
Pages: 887-892
Published online on: 01 October 2008

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Article

Methylation-associated silencing of TU3A in human cancers

Yasuo Awakura, Eijiro Nakamura, Noriyuki Ito, Toshiyuki Kamoto, Osamu Ogawa
Pages: 893-899
Published online on: 01 October 2008

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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