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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2009 Volume 35 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Activation of two distinct MAPK pathways governs constitutive expression of matrix metalloproteinase-1 in human pancreatic cancer cell lines

Hitoshi Endo, Tetsu Watanabe, Yoshihiko Sugioka, Maki Niioka, Yutaka Inagaki, Isao Okazaki
Pages: 1237-1245
Published online on: 01 December 2009

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Article Open Access

Bcr-Abl fusion sequences do not induce immune responses in mice when administered in mouse polyomavirus based virus-like particles

Veronika Hrusková, Alena Morávková, Katarina Babiarová, Viera Ludvíková, Jan Fric, Vladimír Vonka, Jitka Forstová
Pages: 1247-1256
Published online on: 01 December 2009

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Article

Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1 and CDK2 in human hepatocellular carcinoma

Jeong Kyu Kim, Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Hyun Jin Bae, Hong Jian Xie, Young Min Ahn, Jae Chun Ryu, Won Sang Park, Jung Young Lee, Suk Woo Nam
Pages: 1257-1264
Published online on: 01 December 2009

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Article

Use of genetically engineered bone marrow-derived mesenchymal stem cells for glioma gene therapy

Shinji Amano, Shaoyi Li, Chunyu Gu, Yun Gao, Shinichiro Koizumi, Seiji Yamamoto, Susumu Terakawa, Hiroki Namba
Pages: 1265-1270
Published online on: 01 December 2009

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Article

Localization of cortactin is associated with colorectal cancer development

Hiroshi Hirakawa, Kenichiro Shibata, Toshiyuki Nakayama
Pages: 1271-1276
Published online on: 01 December 2009

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Article

α-tocopheryl phosphate suppresses tumor invasion concurrently with dynamic morphological changes and delocalization of cortactin from invadopodia

Yasukazu Saitoh, Atsushi Yumoto, Nobuhiko Miwa
Pages: 1277-1288
Published online on: 01 December 2009

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Article Open Access

Dysregulation of the cell survival/anti-apoptotic NF-κB pathway by the novel humanized BM-ca anti-CD20 mAb: Implication in chemosensitization

Mario I. Vega, Melisa Martínez-Paniagua, Sara Huerta-Yepez, Cesar González-Bonilla, Norio Uematsu, Benjamin Bonavida
Pages: 1289-1296
Published online on: 01 December 2009

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Article

Cigarette smoke-induced DNA damage and repair detected by the comet assay in HPV-transformed cervical cells

Afsoon Moktar, Srivani Ravoori, Manicka V. Vadhanam, C. Gary Gairola, Ramesh C. Gupta
Pages: 1297-1304
Published online on: 01 December 2009

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Article

Inhibition of endothelial cell chemotaxis toward FGF-2 by gefitinib associates with downregulation of Fes activity

Shigeru Kanda, Alexandra Naba, Yasuyoshi Miyata
Pages: 1305-1312
Published online on: 01 December 2009

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Article

Risk of gastric cancer is associated with the MUC1 568 A/G polymorphism

Qian Xu, Yuan Yuan, Li-Ping Sun, Yue-Hua Gong, Ying Xu, Xiu-Wen Yu, Nan-Nan Dong, G. David Lin, Paul N. Smith, Rachel W. Li
Pages: 1313-1320
Published online on: 01 December 2009

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Article Open Access

Gene expression profiling of archival tongue squamous cell carcinomas provides sub-classification based on DNA repair genes

Matilda Rentoft, Göran Laurell, Philip John Coates, Björn Sjöström, Karin Nylander
Pages: 1321-1330
Published online on: 01 December 2009

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Article

Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN

Yun-Chul Kim, Hirotake Kitaura, Takahiro Taira, Sanae M.M. Iguchi-Ariga, Hiroyoshi Ariga
Pages: 1331-1341
Published online on: 01 December 2009

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Article

MicroRNAs that respond to histone deacetylase inhibitor SAHA and p53 in HCT116 human colon carcinoma cells

Sangsu Shin, Eun-Mee Lee, Hwa Jun Cha, Seunghee Bae, Jin Hyuk Jung, Sun-Mi Lee, Youngmin Yoon, Hyunjin Lee, Sumi Kim, Hyunsook Kim, Su-Jae Lee, In-Chul Park, Young-Woo Jin, Sungkwan An
Pages: 1343-1352
Published online on: 01 December 2009

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Article

A novel resveratrol analogue HS-1793 treatment overcomes the resistance conferred by Bcl-2 and is associated with the formation of mature PML nuclear bodies in renal clear cell carcinoma Caki-1 cells

Seung Hun Jeong, Jee Suk Lee, Na Young Jeong, Tae Hyun Kim, Ki Soo Yoo, Suhee Song, Hongsuk Suh, Taeg Kyu Kwon, Bong Soo Park, Young Hyun Yoo
Pages: 1353-1360
Published online on: 01 December 2009

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Article

AAV2-mediated interleukin-12 in the treatment of malignant brain tumors through activation of NK cells

Tsung-Lang Chiu, Shinn-Zong Lin, Wan-Hua Hsieh, Chih-Wen Peng
Pages: 1361-1367
Published online on: 01 December 2009

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Article Open Access

Fatty acid synthase activity regulates HER2 extracellular domain shedding into the circulation of HER2-positive metastatic breast cancer patients

Alejandro Vazquez-Martin, Jose Manuel Fernandez-Real, Cristina Oliveras-Ferraros, Jose Maria Navarrete, Begoña Martin-Castillo, Sonia Del Barco, Joan Brunet, Javier A. Menendez
Pages: 1369-1376
Published online on: 01 December 2009

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Article

Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues

Eva-Maria Fabricius, Ute Kruse-Boitschenko, Reem Khoury, Gustav-Paul Wildner, Jan-Dirk Raguse, Martin Klein, Bodo Hoffmeister
Pages: 1377-1394
Published online on: 01 December 2009

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Article

Microarray gene expression profiling in meningiomas: Differential expression according to grade or histopathological subtype

Michelle Fèvre-Montange, Jacques Champier, Anne Durand, Anne Wierinckx, Jérome Honnorat, Jacques Guyotat, Anne Jouvet
Pages: 1395-1407
Published online on: 01 December 2009

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Article

Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines

Sujin Chae, Hyoung-Oh Jun, Eun Gyo Lee, Suk-Jin Yang, Dong Chul Lee, Joon Ki Jung, Kyung Chan Park, Young Il Yeom, Kyu-Won Kim
Pages: 1409-1416
Published online on: 01 December 2009

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Article

Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells

Shundong Cang, Jingyang Feng, Sensuke Konno, Liying Han, Katherine Liu, Sansar C. Sharma, Muhammad Choudhury, J. W. Chiao
Pages: 1417-1422
Published online on: 01 December 2009

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Article

Vasculogenic mimicry of human ovarian cancer cells: Role of CD147

Danilo Millimaggi, Marianna Mari, Sandra D' Ascenzo, Ilaria Giusti, Antonio Pavan, Vincenza Dolo
Pages: 1423-1428
Published online on: 01 December 2009

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Article

Cell density-dependent regulation of p73 in breast cancer cells

Chaitali Tophkhane, Shihe Yang, Zhizhuang Joe Zhao, Xiaohe Yang
Pages: 1429-1434
Published online on: 01 December 2009

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Article

Thioredoxin2 enhances the damaged DNA binding activity of mtTFA through direct interaction

Akihiko Kidani, Hiroto Izumi, Yoichiro Yoshida, Eiji Kashiwagi, Haruki Ohmori, Tsuneo Tanaka, Michihiko Kuwano, Kimitoshi Kohno
Pages: 1435-1440
Published online on: 01 December 2009

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Article Open Access

Modulation of the transforming growth factor-β1-induced Smad phosphorylation by the extracellular matrix receptor β1-integrin

Hiroshi Hamajima, Iwata Ozaki, Hao Zhang, Shinji Iwane, Yasunori Kawaguchi, Yuichiro Eguchi, Sachiko Matsuhashi, Toshihiko Mizuta, Koichi Matsuzaki, Kazuma Fujimoto
Pages: 1441-1447
Published online on: 01 December 2009

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Article

Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma

Evzen Krepela, Petra Dankova, Erika Moravcikova, Anna Krepelova, Jan Prochazka, Jan Cermak, Jan Schützner, Petr Zatloukal, Kamila Benkova
Pages: 1449-1462
Published online on: 01 December 2009

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Article

The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells

Leong-Uung Ling, Huimin Lin, Kuan-Boone Tan, Gigi N.C. Chiu
Pages: 1463-1471
Published online on: 01 December 2009

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Article

Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro

Ning Zhang, Andrew J. Sanders, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Pages: 1473-1480
Published online on: 01 December 2009

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Article

Novel 8-hydroxylquinoline analogs induce copper-dependent proteasome inhibition and cell death in human breast cancer cells

Vesna Milacic, Peifu Jiao, Bin Zhang, Bing Yan, Q. Ping Dou
Pages: 1481-1491
Published online on: 01 December 2009

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Article

The adenoviral E1A oncoprotein activates the Smad7 promoter: Requirement of a functional E-box

Vandana S. Dole, Hans Smola, Steven Dooley, Harun M. Said, Monika Oldak, Herbert J. Pfister, Sigrun Smola
Pages: 1493-1498
Published online on: 01 December 2009

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Article

Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK

Dong Yeok Shin, Won Sup Lee, Jing Nan Lu, Myung Hee Kang, Chung Ho Ryu, Gi Young Kim, Ho Sung Kang, Sung Chul Shin, Yung Hyun Choi
Pages: 1499-1504
Published online on: 01 December 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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