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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2009 Volume 35 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Activation of two distinct MAPK pathways governs constitutive expression of matrix metalloproteinase-1 in human pancreatic cancer cell lines

Hitoshi Endo, Tetsu Watanabe, Yoshihiko Sugioka, Maki Niioka, Yutaka Inagaki, Isao Okazaki
Pages: 1237-1245
Published online on: 01 December 2009

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Article Open Access

Bcr-Abl fusion sequences do not induce immune responses in mice when administered in mouse polyomavirus based virus-like particles

Veronika Hrusková, Alena Morávková, Katarina Babiarová, Viera Ludvíková, Jan Fric, Vladimír Vonka, Jitka Forstová
Pages: 1247-1256
Published online on: 01 December 2009

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Article

Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1 and CDK2 in human hepatocellular carcinoma

Jeong Kyu Kim, Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Hyun Jin Bae, Hong Jian Xie, Young Min Ahn, Jae Chun Ryu, Won Sang Park, Jung Young Lee, Suk Woo Nam
Pages: 1257-1264
Published online on: 01 December 2009

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Article

Use of genetically engineered bone marrow-derived mesenchymal stem cells for glioma gene therapy

Shinji Amano, Shaoyi Li, Chunyu Gu, Yun Gao, Shinichiro Koizumi, Seiji Yamamoto, Susumu Terakawa, Hiroki Namba
Pages: 1265-1270
Published online on: 01 December 2009

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Article

Localization of cortactin is associated with colorectal cancer development

Hiroshi Hirakawa, Kenichiro Shibata, Toshiyuki Nakayama
Pages: 1271-1276
Published online on: 01 December 2009

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Article

α-tocopheryl phosphate suppresses tumor invasion concurrently with dynamic morphological changes and delocalization of cortactin from invadopodia

Yasukazu Saitoh, Atsushi Yumoto, Nobuhiko Miwa
Pages: 1277-1288
Published online on: 01 December 2009

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Article Open Access

Dysregulation of the cell survival/anti-apoptotic NF-κB pathway by the novel humanized BM-ca anti-CD20 mAb: Implication in chemosensitization

Mario I. Vega, Melisa Martínez-Paniagua, Sara Huerta-Yepez, Cesar González-Bonilla, Norio Uematsu, Benjamin Bonavida
Pages: 1289-1296
Published online on: 01 December 2009

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Article

Cigarette smoke-induced DNA damage and repair detected by the comet assay in HPV-transformed cervical cells

Afsoon Moktar, Srivani Ravoori, Manicka V. Vadhanam, C. Gary Gairola, Ramesh C. Gupta
Pages: 1297-1304
Published online on: 01 December 2009

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Article

Inhibition of endothelial cell chemotaxis toward FGF-2 by gefitinib associates with downregulation of Fes activity

Shigeru Kanda, Alexandra Naba, Yasuyoshi Miyata
Pages: 1305-1312
Published online on: 01 December 2009

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Article

Risk of gastric cancer is associated with the MUC1 568 A/G polymorphism

Qian Xu, Yuan Yuan, Li-Ping Sun, Yue-Hua Gong, Ying Xu, Xiu-Wen Yu, Nan-Nan Dong, G. David Lin, Paul N. Smith, Rachel W. Li
Pages: 1313-1320
Published online on: 01 December 2009

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Article Open Access

Gene expression profiling of archival tongue squamous cell carcinomas provides sub-classification based on DNA repair genes

Matilda Rentoft, Göran Laurell, Philip John Coates, Björn Sjöström, Karin Nylander
Pages: 1321-1330
Published online on: 01 December 2009

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Article

Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN

Yun-Chul Kim, Hirotake Kitaura, Takahiro Taira, Sanae M.M. Iguchi-Ariga, Hiroyoshi Ariga
Pages: 1331-1341
Published online on: 01 December 2009

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Article

MicroRNAs that respond to histone deacetylase inhibitor SAHA and p53 in HCT116 human colon carcinoma cells

Sangsu Shin, Eun-Mee Lee, Hwa Jun Cha, Seunghee Bae, Jin Hyuk Jung, Sun-Mi Lee, Youngmin Yoon, Hyunjin Lee, Sumi Kim, Hyunsook Kim, Su-Jae Lee, In-Chul Park, Young-Woo Jin, Sungkwan An
Pages: 1343-1352
Published online on: 01 December 2009

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Article

A novel resveratrol analogue HS-1793 treatment overcomes the resistance conferred by Bcl-2 and is associated with the formation of mature PML nuclear bodies in renal clear cell carcinoma Caki-1 cells

Seung Hun Jeong, Jee Suk Lee, Na Young Jeong, Tae Hyun Kim, Ki Soo Yoo, Suhee Song, Hongsuk Suh, Taeg Kyu Kwon, Bong Soo Park, Young Hyun Yoo
Pages: 1353-1360
Published online on: 01 December 2009

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Article

AAV2-mediated interleukin-12 in the treatment of malignant brain tumors through activation of NK cells

Tsung-Lang Chiu, Shinn-Zong Lin, Wan-Hua Hsieh, Chih-Wen Peng
Pages: 1361-1367
Published online on: 01 December 2009

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Article Open Access

Fatty acid synthase activity regulates HER2 extracellular domain shedding into the circulation of HER2-positive metastatic breast cancer patients

Alejandro Vazquez-Martin, Jose Manuel Fernandez-Real, Cristina Oliveras-Ferraros, Jose Maria Navarrete, Begoña Martin-Castillo, Sonia Del Barco, Joan Brunet, Javier A. Menendez
Pages: 1369-1376
Published online on: 01 December 2009

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Article

Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues

Eva-Maria Fabricius, Ute Kruse-Boitschenko, Reem Khoury, Gustav-Paul Wildner, Jan-Dirk Raguse, Martin Klein, Bodo Hoffmeister
Pages: 1377-1394
Published online on: 01 December 2009

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Article

Microarray gene expression profiling in meningiomas: Differential expression according to grade or histopathological subtype

Michelle Fèvre-Montange, Jacques Champier, Anne Durand, Anne Wierinckx, Jérome Honnorat, Jacques Guyotat, Anne Jouvet
Pages: 1395-1407
Published online on: 01 December 2009

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Article

Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines

Sujin Chae, Hyoung-Oh Jun, Eun Gyo Lee, Suk-Jin Yang, Dong Chul Lee, Joon Ki Jung, Kyung Chan Park, Young Il Yeom, Kyu-Won Kim
Pages: 1409-1416
Published online on: 01 December 2009

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Article

Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells

Shundong Cang, Jingyang Feng, Sensuke Konno, Liying Han, Katherine Liu, Sansar C. Sharma, Muhammad Choudhury, J. W. Chiao
Pages: 1417-1422
Published online on: 01 December 2009

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Article

Vasculogenic mimicry of human ovarian cancer cells: Role of CD147

Danilo Millimaggi, Marianna Mari, Sandra D' Ascenzo, Ilaria Giusti, Antonio Pavan, Vincenza Dolo
Pages: 1423-1428
Published online on: 01 December 2009

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Article

Cell density-dependent regulation of p73 in breast cancer cells Corrigendum in /10.3892/ijo.2026.5898

Chaitali Tophkhane, Shihe Yang, Zhizhuang Joe Zhao, Xiaohe Yang
Pages: 1429-1434
Published online on: 01 December 2009

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Article

Thioredoxin2 enhances the damaged DNA binding activity of mtTFA through direct interaction

Akihiko Kidani, Hiroto Izumi, Yoichiro Yoshida, Eiji Kashiwagi, Haruki Ohmori, Tsuneo Tanaka, Michihiko Kuwano, Kimitoshi Kohno
Pages: 1435-1440
Published online on: 01 December 2009

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Article Open Access

Modulation of the transforming growth factor-β1-induced Smad phosphorylation by the extracellular matrix receptor β1-integrin

Hiroshi Hamajima, Iwata Ozaki, Hao Zhang, Shinji Iwane, Yasunori Kawaguchi, Yuichiro Eguchi, Sachiko Matsuhashi, Toshihiko Mizuta, Koichi Matsuzaki, Kazuma Fujimoto
Pages: 1441-1447
Published online on: 01 December 2009

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Article

Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma

Evzen Krepela, Petra Dankova, Erika Moravcikova, Anna Krepelova, Jan Prochazka, Jan Cermak, Jan Schützner, Petr Zatloukal, Kamila Benkova
Pages: 1449-1462
Published online on: 01 December 2009

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Article

The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells

Leong-Uung Ling, Huimin Lin, Kuan-Boone Tan, Gigi N.C. Chiu
Pages: 1463-1471
Published online on: 01 December 2009

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Article

Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro

Ning Zhang, Andrew J. Sanders, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Pages: 1473-1480
Published online on: 01 December 2009

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Article

Novel 8-hydroxylquinoline analogs induce copper-dependent proteasome inhibition and cell death in human breast cancer cells

Vesna Milacic, Peifu Jiao, Bin Zhang, Bing Yan, Q. Ping Dou
Pages: 1481-1491
Published online on: 01 December 2009

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Article

The adenoviral E1A oncoprotein activates the Smad7 promoter: Requirement of a functional E-box

Vandana S. Dole, Hans Smola, Steven Dooley, Harun M. Said, Monika Oldak, Herbert J. Pfister, Sigrun Smola
Pages: 1493-1498
Published online on: 01 December 2009

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Article

Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK

Dong Yeok Shin, Won Sup Lee, Jing Nan Lu, Myung Hee Kang, Chung Ho Ryu, Gi Young Kim, Ho Sung Kang, Sung Chul Shin, Yung Hyun Choi
Pages: 1499-1504
Published online on: 01 December 2009

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Resistance to covalent Bruton's tyrosine kinase inhibitors in diffuse large B‑cell lymphoma: Molecular mechanisms and therapeutic implications (Review)

Chuanyang Lu, Tingting Zhou, Wenxin Zhang, Lulu Wei, Qiuni Chen, Yuye Shi, Chunling Wang, Liang Yu
Article Number: 134
Published online on: 09 October 2026

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Review Open Access

Comprehensive landscape and future perspectives of PIWI‑interacting RNAs in cancer (Review)

Xiaoqian Yu, Changlong Li, Tongtao Zhuang, Siqing Sun, Xiaoyun He, Zhenyu Ou, Nannan Li, Chunlin Ou
Article Number: 133
Published online on: 09 October 2026

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Review Open Access

Nucleocytoplasmic transport in gynaecological cancer: From mechanisms to therapeutic potential (Review)

Ieva Norkaityte, Laura Marija Racyte, Egle Balciunaite, Aiste Avizaite, Egle Zalyte
Article Number: 132
Published online on: 08 October 2026

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Review Open Access

cGAS‑STING pathway in digestive tract cancer: From molecular mechanisms to therapeutic applications (Review)

Tangna Chen, Jingyi Zhang, Jinghan Sun, Hongyan Zhang, Deqiang Huang, Haifeng Ye
Article Number: 131
Published online on: 07 October 2026

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Review Open Access

Regulatory T cells in lung adenocarcinoma: Mechanisms of immune escape, prognostic significance and therapeutic opportunities (Review)

Lijuan Wang, Chenjin Ruan
Article Number: 130
Published online on: 06 October 2026

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Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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Journal Cover
December-2026 Volume 69 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Disporum cantoniense suppresses non‑small cell lung cancer through AMPK/mTOR/ULK1‑mediated autophagy‑dependent apoptosis

Chi Feng, Yujiao Ji, Renqiang Chen, Qiuxu Chen, Yiru Pan, Jianming Wu, Dalian Qin, Betty Yuen Kwan Law, Vincent Kam Wai Wong, Xiaogang Zhou, Jianxin Liu, Anguo Wu
Article Number: 137
Published online on: 15 October 2026

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Review Open Access

Research progress of SPP1 in cancer regulation: Tumorigenesis, metastasis, tumor microenvironment, immunity and therapeutic targets (Review)

Yujun Xia, Dong Han, Song Tang, Huimin Yang, Rongjie Zhao, Beibei Cao, Peixi Zhu, Aiqin Shi, Huacheng Luo
Article Number: 136
Published online on: 14 October 2026

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Correction Open Access

[Corrigendum] Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER‑inhibitors is accompanied by increased sensitivity to STAT3 inhibition

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, David Mackintosh, Flavio Solca, Helmout Modjtahedi
Article Number: 135
Published online on: 09 October 2026

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