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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2010 Volume 36 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Molecular mechanisms of inhibition of photocarcinogenesis by silymarin, a phytochemical from milk thistle (Silybum marianum L. Gaertn.) (Review)

Mudit Vaid, Santosh K. Katiyar
Pages: 1053-1060
Published online on: 01 May 2010

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Review

Playing in three makes it simpler: Mapping the cognitive figure-ground framework onto cancer-immunology and immunotherapy (Review)

Yori Gidron, Luca Vannucci
Pages: 1061-1065
Published online on: 01 May 2010

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Article

Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors α and β

Akhilesh Kumar, Carolyn M. Klinge, Richard E. Goldstein
Pages: 1067-1080
Published online on: 01 May 2010

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Article

DNA damage detected with γH2AX in endometrioid adenocarcinoma cell lines

Maki Ikeda, Akira Kurose, Eriko Takatori, Toru Sugiyama, Frank Traganos, Zbigniew Darzynkiewicz, Takashi Sawai
Pages: 1081-1088
Published online on: 01 May 2010

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Article

Clinicopathological and prognostic significance of PDCD4 and microRNA-21 in human gastric cancer

Kazuo Motoyama, Hiroshi Inoue, Koshi Mimori, Fumiaki Tanaka, Kazuyuki Kojima, Hiroyuki Uetake, Kenichi Sugihara, Masaki Mori
Pages: 1089-1095
Published online on: 01 May 2010

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Article

NAC1, a potential stem cell pluripotency factor expression in normal endometrium, endometrial hyperplasia and endometrial carcinoma

Masako Ishikawa, Kentaro Nakayama, Shamima Yeasmin, Atsuko Katagiri, Kouji Iida, Naomi Nakayama, Kohji Miyazaki
Pages: 1097-1103
Published online on: 01 May 2010

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Article

Hs.137007 is a novel epigenetic marker hypermethylated and up-regulated in breast cancer

Tae Woo Kim, Yoo Jung Kim, Hyun Ji Lee, Sun Young Min, Han-Sung Kang, Sun Jung Kim
Pages: 1105-1111
Published online on: 01 May 2010

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Article

Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9

Ya-Yin Chen, Su-Yin Chiang, Jaung-Geng Lin, Yi-Shih Ma, Ching-Lung Liao, Shu-Wen Weng, Tung-Yuan Lai, Jing-Gung Chung
Pages: 1113-1120
Published online on: 01 May 2010

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Article

A vector-based short hairpin RNA targeting Aurora A inhibits breast cancer growth

Yang Wan, Anliang Huang, Yang Yang, Gang Xie, Xiang Chen, Jia Hu, Xiancheng Chen, Li Yang, Jiong Li, Lijuan Chen, Yu Jiang, Xia Zhao, Yuquan Wei, Hongxin Deng
Pages: 1121-1128
Published online on: 01 May 2010

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Article

Differential expression of the CCN family member WISP-1, WISP-2 and WISP-3 in human colorectal cancer and the prognostic implications

Simon R. Davies, Mansel Leigh Davies, Andrew Sanders, Chris Parr, Jared Torkington, Wen G. Jiang
Pages: 1129-1136
Published online on: 01 May 2010

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Article

KRAS mutations in Slovene patients with colorectal cancer: frequency, distribution and correlation with the response to treatment

Alenka Licar, Petra Cerkovnik, Janja Ocvirk, Srdjan Novakovic
Pages: 1137-1144
Published online on: 01 May 2010

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Article

Cytokeratin 18 expression pattern correlates with renal cell carcinoma progression: Relationship with Snail

Yosra Messai, Muhammad Zaeem Noman, Amine Derouiche, Nadia Kourda, Intissar Akalay, Meriem Hasmim, Izabela Stasik, Sarra Ben Jilani, Mohamed Chebil, Anne Caignard, Bruno Azzarone, Asma Gati, Amel Ben Ammar Elgaaied, Salem Chouaib
Pages: 1145-1154
Published online on: 01 May 2010

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Article

Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion

Charles Edo De Bock, Zhen Lin, Ahmed H. Mekkawy, Jennifer A. Byrne, Yao Wang
Pages: 1155-1163
Published online on: 01 May 2010

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Article

Induction of apoptosis in glioma cells requires cell-to-cell contact with human umbilical cord blood stem cells

Christopher S. Gondi, Venkateswara R. Gogineni, Chandramu Chetty, Venkata R. Dasari, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Pages: 1165-1173
Published online on: 01 May 2010

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Article Open Access

Mapping of the interaction sites between Wee1 kinase and the regulatory β-subunit of protein kinase CK2

Birgitte B. Olsen, Jan N. Kreutzer, Nobumoto Watanabe, Tina Holm, Barbara Guerra
Pages: 1175-1182
Published online on: 01 May 2010

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Article

Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells

Clemence Lepage, Bertrand Liagre, Jeanne Cook-Moreau, Aline Pinon, Jean-Louis Beneytout
Pages: 1183-1191
Published online on: 01 May 2010

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Article

The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells

Shigeto Matsushita, Ryuji Ikeda, Yukihiko Nishizawa, Xiao-Fang Che, Tatsuhiko Furukawa, Kazutaka Miyadera, Sho Tabata, Mina Ushiyama, Yusuke Tajitsu, Masatatsu Yamamoto, Yasuo Takeda, Kentaro Minami, Hironori Mataki, Tamotsu Kanzaki, Katsushi Yamada, Takuro Kanekura, Shin-Ichi Akiyama
Pages: 1193-1200
Published online on: 01 May 2010

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Article

Enforced SOCS1 and SOCS3 expression attenuates Lck-mediated cellular transformation

John C. Cooper, Mingjian Shi, Fu-Yu Chueh, Srividya Venkitachalam, Chao-Lan Yu
Pages: 1201-1208
Published online on: 01 May 2010

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Article

MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway

Paloma Ortega, Alberto Moran, Tamara Fernandez-Marcelo, Carmen De Juan, Cristina Frias, José-Antonio Lopez-Asenjo, Andrés Sanchez-Pernaute, Antonio Torres, Eduardo Diaz-Rubio, Pilar Iniesta, Manuel Benito
Pages: 1209-1215
Published online on: 01 May 2010

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Article

Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer

Marina Arifin, Keiji Tanimoto, Andika Chandra Putra, Eiso Hiyama, Masahiko Nishiyama, Keiko Hiyama
Pages: 1217-1227
Published online on: 01 May 2010

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Article

Target cell-restricted apoptosis induction by 528scFv-TRAIL fusion protein specific for human EGFR and expressed in Escherichia coli

Adel Badran, Ryutaro Asano, Makoto Nakayama, Yasuhiro Watanabe, Takeshi Nakanishi, Mitsuo Umetsu, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Izumi Kumagai
Pages: 1229-1234
Published online on: 01 May 2010

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Article

Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells

Lena Kastl, Iain Brown, Andrew C. Schofield
Pages: 1235-1241
Published online on: 01 May 2010

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Article

Hemin inhibits cyclin D1 and IGF-1 expression via STAT5b under hypoxia in ERα-negative MDA-MB 231 breast cancer cells

Eun-Joung Lim, Youn-Hee Joung, Se-Mi Jung, Se Hyung Park, Jin Hee Park, Sang Yoon Kim, Tae Sook Hwang, Dae Young Hong, So Chung Chung, Sang-Kyu Ye, Eon-Soo Moon, Eui U. Park, Taekyu Park, Ill-Min Chung, Young Mok Yang
Pages: 1243-1251
Published online on: 01 May 2010

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Article

Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis

Yuji Miyamoto, Manabu Futamura, Noriaki Kitamura, Yasuyuki Nakamura, Hideo Baba, Hiroufmi Arakawa
Pages: 1253-1260
Published online on: 01 May 2010

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Article

Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation

S. Grotegut, R. Kappler, S. Tarimoradi, F. Lehembre, G. Christofori, D. Von Schweinitz
Pages: 1261-1267
Published online on: 01 May 2010

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Article

PNUTS knockdown potentiates the apoptotic effect of Roscovitine in breast and colon cancer cells

Gabriel De Leon, Margaret Cavino, Mikilyn D'Angelo, Nancy A. Krucher
Pages: 1269-1275
Published online on: 01 May 2010

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Article

Metastases of squamous cell carcinoma of the head and neck show increased levels of nucleotide excision repair protein XPF in vivo that correlate with increased chemoresistance ex vivo

Beate Köberle, Claudia Ditz, Ingo Kausch, Barbara Wollenberg, Robert L. Ferris, Andreas E. Albers
Pages: 1277-1284
Published online on: 01 May 2010

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Article

Effects of growth hormone-releasing hormone and its agonistic and antagonistic analogs in cancer and non-cancerous cell lines

Nektarios Barabutis, Agnieszka Siejka, Andrew V. Schally
Pages: 1285-1289
Published online on: 01 May 2010

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Article

Dimeric Lea (Lea-on-Lea) status of β-haptoglobin in sera of colon cancer, chronic inflammatory disease and normal subjects

Seung-Yeol Park, Seon-Joo Yoon, Sen-Itiroh Hakomori, Jin-Man Kim, Ji-Yeon Kim, Bradford Bernert, Thomas Ullman, Steven H. Itzkowitz, Jung Hoe Kim
Pages: 1291-1297
Published online on: 01 May 2010

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Article

Inhibition of NF-κB and Akt pathways by an antibody-avidin fusion protein sensitizes malignant B-cells to cisplatin-induced apoptosis

Eriko Suzuki, Tracy R. Daniels, Gustavo Helguera, Manuel L. Penichet, Kazuo Umezawa, Benjamin Bonavida
Pages: 1299-1307
Published online on: 01 May 2010

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Article

Fatty acid synthesis is a therapeutic target in human liposarcoma

Arne M. Olsen, Burton L. Eisenberg, Nancy B. Kuemmerle, Alison J. Flanagan, Peter M. Morganelli, Portia S. Lombardo, Johannes V. Swinnen, William B. Kinlaw
Pages: 1309-1314
Published online on: 01 May 2010

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Correction Open Access

[Corrigendum] Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, with potential anti-tumor activity against apoptosis-resistant cancer cells

El-Hadj Saidou Balde, Véronique Mégalizzi, Martine Cao, Luc Angenot, Robert Kiss, Marc Van Damme, Michel Frederich
Pages: 1315-1315
Published online on: 09 December 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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