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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2010 Volume 37 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Granzyme B-induced apoptosis in cancer cells and its regulation (Review)

Ilona Rousalova, Evzen Krepela
Pages: 1361-1378
Published online on: 01 December 2010

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Article Open Access

CpG hypermethylation of cellular retinol-binding protein 1 contributes to cell proliferation and migration in bladder cancer

Kazuki Toki, Hideki Enokida, Kazumori Kawakami, Takeshi Chiyomaru, Shuichi Tatarano, Hirofumi Yoshino, Yousuke Uchida, Kazuya Kawahara, Kenryu Nishiyama, Naohiko Seki, Masayuki Nakagawa
Pages: 1379-1388
Published online on: 01 December 2010

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Article Open Access

Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: Activity and toxicity profile

Johannes Dreischalück, Christian Schwöppe, Tilmann Spieker, Torsten Kessler, Klaus Tiemann, Ruediger Liersch, Christoph Schliemann, Michael Kreuter, Astrid Kolkmeyer, Heike Hintelmann, Rolf M. Mesters, Wolfgang E. Berdel
Pages: 1389-1397
Published online on: 01 December 2010

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Article Open Access

Cytostatic response of HepG2 to 0.57 MHz electric currents mediated by changes in cell cycle control proteins

María Luisa Hernández-Bule, María Antonia Cid, María Ángeles Trillo, Jocelyne Leal, Alejandro Úbeda
Pages: 1399-1405
Published online on: 01 December 2010

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Article Open Access

Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene

Ikuko Yokota, Yasushi Sasaki, Lisa Kashima, Masashi Idogawa, Takashi Tokino
Pages: 1407-1416
Published online on: 01 December 2010

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Article

Expression of α-taxilin in hepatocellular carcinoma correlates with growth activity and malignant potential of the tumor

Natsuko Ohtomo, Tomoaki Tomiya, Yasushi Tanoue, Yukiko Inoue, Takako Nishikawa, Hitoshi Ikeda, Yasuji Seyama, Norihiro Kokudo, Junji Shibahara, Masashi Fukayama, Kazuhiko Koike, Hiromichi Shirataki, Kenji Fujiwara
Pages: 1417-1423
Published online on: 01 December 2010

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Identification of natural antisense transcripts involved in human colorectal cancer development

Keisuke Kohno, Mitsuru Chiba, Soichiro Murata, Sugiru Pak, Kentaro Nagai, Masayoshi Yamamoto, Kazuhiko Yanagisawa, Akihiko Kobayashi, Hiroshi Yasue, Nobuhiro Ohkohchi
Pages: 1425-1432
Published online on: 01 December 2010

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Article

Efficacy of oncolytic reovirus against human gastric cancer with peritoneal metastasis in experimental animal model

Koji Kawaguchi, Tsuyoshi Etoh, Kosuke Suzuki, Marcelo Takahiro Mitui, Akira Nishizono, Norio Shiraishi, Seigo Kitano
Pages: 1433-1438
Published online on: 01 December 2010

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Transcriptome analysis and cytokine profiling of naive T cells stimulated by a tumor vaccine via CD3 and CD25

Philippe Fournier, Maximilian Aigner, Volker Schirrmacher
Pages: 1439-1452
Published online on: 01 December 2010

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Article

Oncologic trogocytosis with Hospicells induces the expression of N-cadherin by breast cancer cells

Raphaël Lis, Jérome Capdet, Pejman Mirshahi, Magali Lacroix-Triki, Francoise Dagonnet, Christophe Klein, Massoud Mirshahi, Jean-Jacques Fournié, Arash Rafii, Mary Poupot
Pages: 1453-1461
Published online on: 01 December 2010

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Alternative responses of primary tumor cells and glioblastoma cell lines to N,N-bis-(8-hydroxyquinoline-5-yl methyl)-benzyl substituted amines: Cell death versus P53-independent senescence

Jean-Louis Kraus, Filippo Conti, Sébastien Madonna, Aurelie Tchoghandjian, Christophe Beclin
Pages: 1463-1470
Published online on: 01 December 2010

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Cyclin D1 and cyclin D-dependent kinases enhance oral keratinocyte proliferation but do not block keratinocyte differentiation

Michael Woods, Rima Pant, Sanjay M. Mallya
Pages: 1471-1475
Published online on: 01 December 2010

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Establishment and characterization of a pair of non-malignant and malignant tumor derived cell lines from an African American prostate cancer patient

Shaniece Theodore, Starlette Sharp, Jianjun Zhou, Timothy Turner, Hongzhen Li, Jun Miki, Youngmi Ji, Vyomesh Patel, Clayton Yates, Johng S. Rhim
Pages: 1477-1482
Published online on: 01 December 2010

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Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells Expression of Concern in /10.3892/ijo.2025.5814

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Pages: 1483-1493
Published online on: 01 December 2010

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Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development

Kai Zhang, Masami Watanabe, Yuji Kashiwakura, Shun-Ai Li, Kohei Edamura, Peng Huang, Ken Yamaguchi, Yasutomo Nasu, Yasuyuki Kobayashi, Masakiyo Sakaguchi, Kazuhiko Ochiai, Hiroshi Yamada, Kohji Takei, Hideo Ueki, Nam-Ho Huh, Ming Li, Haruki Kaku, Yanqun Na, Hiromi Kumon
Pages: 1495-1501
Published online on: 01 December 2010

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E phage gene transfection enhances sensitivity of lung and colon cancer cells to chemotherapeutic agents

Ana R. Rama, Jose Prados, Consolacion Melguizo, Raul Ortiz, Pablo J. Álvarez, Fernando Rodríguez-Serrano, Fidel Hita, Juan L. Ramos, Miguel Burgos, Antonia Aranega
Pages: 1503-1514
Published online on: 01 December 2010

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Evaluation of the effectiveness of a chemoprevention model of pancreatic adenocarcinoma using protein chip technology

Liping Cao, Liang Wang, Guifeng Wang, Daren Liu, Jiekai Yu, Risheng Que, Dafei Xie
Pages: 1515-1520
Published online on: 01 December 2010

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Molecular cloning and characterization of a novel esophageal cancer related gene

Yongping Cui, Meixia Bi, Tao Su, Hailing Liu, Shih-Hsin Lu
Pages: 1521-1528
Published online on: 01 December 2010

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Article Open Access

Novel medicinal mushroom blend suppresses growth and invasiveness of human breast cancer cells

Jiahua Jiang, Daniel Sliva
Pages: 1529-1536
Published online on: 01 December 2010

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Article Open Access

Distinct epigenetic regulation of tumor suppressor genes in putative cancer stem cells of solid tumors

Hiroyuki Yasuda, Kenzo Soejima, Hideo Watanabe, Ichiro Kawada, Ichiro Nakachi, Satoshi Yoda, Sohei Nakayama, Ryosuke Satomi, Shinnosuke Ikemura, Hideki Terai, Takashi Sato, Sadafumi Suzuki, Yumi Matsuzaki, Katsuhiko Naoki, Akitoshi Ishizaka
Pages: 1537-1546
Published online on: 01 December 2010

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Low expression of Ku70/80, but high expression of DNA-PKcs, predict good response to radiotherapy in early breast cancer

Karin Söderlund Leifler, Siv Queseth, Tommy Fornander, Marie Stenmark Askmalm
Pages: 1547-1554
Published online on: 01 December 2010

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Article

Cellular response to cetuximab in PTEN-silenced head and neck squamous cell carcinoma cell line

Jihane Mriouah, Cedric Boura, Sophie Pinel, Anne-Sophie Chretien, Alexandre Fifre, Jean-Louis Merlin, Beatrice Faivre
Pages: 1555-1563
Published online on: 01 December 2010

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Slumbering mucosal immune response in the cervix of human papillomavirus DNA-positive and -negative women

Sophia Brismar Wendel, Tove Kaldensjö, Pernilla Peterson, Sonia Andersson, Kristina Broliden, Taha Hirbod
Pages: 1565-1573
Published online on: 01 December 2010

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Article

p53 protects lung cancer cells against metabolic stress

Chompunoot Sinthupibulyakit, Wanida Ittarat, William H. St. Clair, Daret K. St. Clair
Pages: 1575-1581
Published online on: 01 December 2010

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Article

Zinc oxide nanoparticles induce photocatalytic cell death in human head and neck squamous cell carcinoma cell lines in vitro

Stephan Hackenberg, Agmal Scherzed, Michael Kessler, Katrin Froelich, Christian Ginzkey, Christian Koehler, Marc Burghartz, Rudolf Hagen, Norbert Kleinsasser
Pages: 1583-1590
Published online on: 01 December 2010

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Article

Expression of P-glycoprotein in HeLa cells confers resistance to ceramide cytotoxicity

Jacqueline V. Chapman, Valérie Gouazé-Andersson, Myles C. Cabot
Pages: 1591-1597
Published online on: 01 December 2010

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Article

FcγR polymorphisms and clinical outcome in colorectal cancer patients receiving passive or active antibody treatment

Biyun Wang, Parviz Kokhaei, Håkan Mellstedt, Maria Liljefors
Pages: 1599-1606
Published online on: 01 December 2010

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Article

L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase

Lidia De Bari, Gabriella Chieppa, Ersilia Marra, Salvatore Passarella
Pages: 1607-1620
Published online on: 01 December 2010

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Article

PUMA is a novel target of miR-221/222 in human epithelial cancers

Chunzhi Zhang, Junxia Zhang, Anlin Zhang, Yingyi Wang, Lei Han, Yongping You, Peiyu Pu, Chunsheng Kang
Pages: 1621-1626
Published online on: 01 December 2010

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Article

Rodent-specific hypoxia response elements enhance PAI-1 expression through HIF-1 or HIF-2 in mouse hepatoma cells

Yong-Tae Ahn, Mei-Sze Chua, James P. Whitlock, Yong-Chil Shin, Woon-Heung Song, Yongkuk Kim, Chi-Yong Eom, Won Gun An
Pages: 1627-1638
Published online on: 01 December 2010

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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