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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2012 Volume 40 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Insight into the role of microRNAs in brain tumors (Review)

Alessia Catania, Francesca Maira, Evangelia  Skarmoutsou, Fabio  D'Amico, Roger Abounader, Maria Clorinda Mazzarino
Pages: 605-624
Published online on: 15 December 2011

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Review

Genetics and molecular epidemiology of multiple myeloma: The rationale for the IMMEnSE consortium (Review)

Alessandro Martino, Juan Sainz, Gabriele Buda, Krzysztof Jamroziak, Rui Manuel Reis, Ramón García-Sanz, Manuel Jurado, Rafael Ríos, Zofia Szemraj-Rogucka, Herlander Marques, Fabienne Lesueur, Victor Moreno, Enrico Orciuolo, Federica Gemignani, Stefano Landi, Anna Maria Rossi, Charles Dumontet, Mario Petrini, Daniele Campa, Federico Canzian
Pages: 625-638
Published online on: 06 December 2011

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Review Open Access

Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (Review)

Sameh Hafsi, Franca Maria Pezzino, Saverio Candido, Giovanni Ligresti, Demetrios A. Spandidos, Zohra Soua, James A. McCubrey, Salvatore Travali, Massimo Libra
Pages: 639-644
Published online on: 20 December 2011

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Article Open Access

Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer

C. J. Watson, H. O'Kane, P. Maxwell, O. Sharaf, I. Petak, P. L. Hyland, D. O'Rouke, J. McKnight, P. Canning, K. Williamson
Pages: 645-654
Published online on: 04 November 2011

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Article Open Access

GATA-binding protein 1 is a novel transcription regulator of peroxiredoxin 5 in human breast cancer cells

Min Ji Seo, Xiyuan Liu, Minsun Chang, Jong Hoon Park
Pages: 655-664
Published online on: 20 October 2011

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Article Open Access

The CD49d+/high subpopulation from isolated human breast sarcoma spheres possesses tumor-initiating ability

Kyung-Min Lee, Wonshik Han, Jong Bin Kim, Incheol Shin, Eunyoung Ko, In Ae Park, Dong Sup Lee, Kuenhee Oh, Dong-Young Noh
Pages: 665-672
Published online on: 08 December 2011

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Article Open Access

The role of the tumor suppressor RUNX3 in giant cell tumor of the bone

Ya-Xin Han, De-Yong Liang
Pages: 673-678
Published online on: 04 November 2011

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Article Open Access

PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells

Hironori Koga, Karuppaiyah Selvendiran, Ramadoss Sivakumar, Takafumi Yoshida, Takuji Torimura, Takato Ueno, Michio Sata
Pages: 679-685
Published online on: 20 October 2011

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Article

Aberrant methylation of the Pleckstrin and Sec7 domain-containing gene is implicated in ulcerative colitis-associated carcinogenesis through its inhibitory effect on apoptosis

Shinichiro Okada, Koichi Suzuki, Kato Takaharu, Hiroshi Noda, Hidenori Kamiyama, Takafumi Maeda, Masaaki Saito, Kei Koizumi, Yuichiro Miyaki, Fumio Konishi
Pages: 686-694
Published online on: 13 October 2011

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Article

Transcriptional and post-transcriptional regulation of βIII-tubulin protein expression in relation with cell cycle-dependent regulation of tumor cells

Masahiko Shibazaki, Chihaya Maesawa, Kiyomi Akasaka, Shuya  Kasai, Shinji Yasuhira, Kiminori Kanno, Ikue Nakayama, Toru Sugiyama, Go Wakabayasi, Tomoyuki Masuda, Nozomu Mori
Pages: 695-702
Published online on: 08 December 2011

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Article

Increased ERK activation and cellular drug accumulation in the enhanced cytotoxicity of folate receptor-targeted liposomal carboplatin

Anumita Chaudhury, Bee Jee Tan, Surajit Das, Gigi N.C. Chiu
Pages: 703-710
Published online on: 11 November 2011

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Article

Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models Retraction in /10.3892/ijo.2025.5717

Giovanni Luca Gravina, Francesco Marampon, Ilaria Giusti, Eleonora Carosa, Stefania Di Sante, Enrico Ricevuto, Vincenza Dolo, Vincenzo Tombolini, Emmanuele A Jannini, Claudio Festuccia
Pages: 711-720
Published online on: 23 November 2011

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Article

Identification and validation of a gene expression signature that predicts outcome in malignant glioma patients

Atsushi Kawaguchi, Naoki Yajima, Yoshihiro Komohara, Hiroshi Aoki, Naoto Tsuchiya, Jumpei Homma, Masakazu Sano, Manabu Natsumeda, Takeo Uzuka, Akihiko Saitoh, Hideaki Takahashi, Yuko Sakai, Hitoshi Takahashi, Yukihiko Fujii, Tatsuyuki Kakuma, Ryuya Yamanaka
Pages: 721-730
Published online on: 21 October 2011

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Article

A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells

Shu-Chun Hsu, Chien-Chih Yu, Jai-Sing Yang, Kuang-Chi Lai, Shin-Hwar Wu, Jen-Jyh Lin, Jehn-Hwa Kuo, Su-Tso Yang, Ching-Che Huang, Sheng-Chu Kuo, Jing-Gung Chung
Pages: 731-738
Published online on: 21 October 2011

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Article

Methylation profiling in non-small cell lung cancer: Clinical implications

Alberto Morán, Tamara Fernández-Marcelo, Juan Carro, Carmen  De Juan, Irene Pascua, Jacqueline Head, Ana Gómez, Florentino Hernando, Antonio-José Torres, Manuel Benito, Pilar Iniesta
Pages: 739-746
Published online on: 07 November 2011

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Article

microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb

Jun Zhang, Na Luo, Yi Luo, Zhiping Peng, Tao Zhang, Shaolin Li
Pages: 747-756
Published online on: 24 October 2011

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Article

Oncolytic herpes simplex virus treatment of metastatic breast cancer

Jiani Wang, Pan Hu, Musheng Zeng, Samuel D. Rabkin, Renbin Liu
Pages: 757-763
Published online on: 21 November 2011

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Article

Therapeutical doses of temozolomide do not impair the function of dendritic cells and CD8+ T cells

Xun Xu, Florian Stockhammer, Anita Schmitt, Rosaely Casalegno-Garduno, Anne Enders, Jiju Mani, Carl Friedrich Classen, Michael Linnebacher, Mathias Freund, Michael Schmitt
Pages: 764-772
Published online on: 23 November 2011

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Article

A phase II study of docetaxel weekly in combination with carboplatin every three weeks as first line chemotherapy in stage IIB-IV epithelial ovarian cancer: Neurological toxicity and quality-of-life evaluation

Bengt Sorbe, Marianne Graflund, Lisa Nygren, György Horvath, Marie Swahn, Karin Boman, René Bangshöj, Margareta Lood, Henric Malmström
Pages: 773-781
Published online on: 07 December 2011

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Article

Two initiation sites of early detection of colon cancer, revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of tumor cells Retraction in /ijo/41/5/1887

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer, Rony Seger
Pages: 782-788
Published online on: 22 November 2011

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Article

DNA binding protein A expression and methylation status in hepatocellular carcinoma and the adjacent tissue

Mahmut Yasen, Gulanbar Obulhasim, Kazunori Kajino, Kaoru Mogushi, Hiroshi Mizushima, Shinji Tanaka, Hiroshi Tanaka, Okio Hino, Shigeki Arii
Pages: 789-797
Published online on: 06 December 2011

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Article

Intrinsic gemcitabine resistance in a novel pancreatic cancer cell line is associated with cancer stem cell-like phenotype

Gang Hu, Fu Li, Kedong Ouyang, Fubo Xie, Xuzhen Tang, Ke Wang, Sufang Han, Zhenzhou Jiang, Minghua Zhu, Danyi Wen, Xiaoran Qin, Luyong Zhang
Pages: 798-806
Published online on: 07 November 2011

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Article

NO donor and MEK inhibitor synergistically inhibit proliferation and invasion of cancer cells

Satoshi Furuhashi, Hiroki Sugita, Hiroshi Takamori, Kei Horino, Osamu Nakahara, Hirohisa Okabe, Keisuke Miyake, Hiroshi Tanaka, Toru Beppu, Hideo Baba
Pages: 807-815
Published online on: 24 October 2011

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Article

Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells

Yasuyuki Izutani, Shingo Yogosawa, Yoshihiro Sowa, Toshiyuki Sakai
Pages: 816-824
Published online on: 27 October 2011

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Article Open Access

Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates

Dimo Dietrich, Christoph Kneip, Olaide Raji, Triantafillos Liloglou, Anke Seegebarth, Thomas Schlegel, Nadja Flemming, Sebastian Rausch, Jürgen Distler, Michael Fleischhacker, Bernd Schmidt, Thomas Giles, Martin Walshaw, Chris Warburton, Volker Liebenberg, John K. Field
Pages: 825-832
Published online on: 16 November 2011

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Article

Serum IL10, IL12 and circulating CD4+CD25high T regulatory cells in relation to long-term clinical outcome in head and neck squamous cell carcinoma patients

Victoria L. Green, Ekpemi Irune, Amit Prasai, Osama Alhamarneh, John Greenman, Nicholas D. Stafford
Pages: 833-839
Published online on: 10 November 2011

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Article

Newcastle disease virus induces pro-inflammatory conditions and type I interferon for counter-acting Treg activity

Philippe Fournier, Annette Arnold, Holger Wilden, Volker Schirrmacher
Pages: 840-850
Published online on: 16 November 2011

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Article

Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA

Christine Challen, John J. Anderson, Zofia   M.A. Chrzanowska‑Lightowlers, Robert N. Lightowlers, John Lunec
Pages: 851-859
Published online on: 21 November 2011

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Article

Transcriptional analysis of CXCR4, DNMT3A, DNMT3B and DNMT1 gene expression in primary advanced uterine cervical carcinoma

Michał W. Łuczak, Andrzej Roszak, Piotr Pawlik, Helena Kędzia, Witold Kędzia, Blanka Malkowska-Walczak, Margarita Lianeri, Paweł P. Jagodziński
Pages: 860-866
Published online on: 01 September 2011

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Article

Statins exhibit anticancer effects through modifications of the pAkt signaling pathway

Erica Miraglia, Johan Högberg, Ulla Stenius
Pages: 867-875
Published online on: 06 October 2011

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Article

AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors

Christoph R. Gloesenkamp, Bianca Nitzsche, Matthias Ocker, Pietro Di Fazio, Karl Quint, Björn Hoffmann, Hans Scherübl, Michael Höpfner
Pages: 876-888
Published online on: 07 November 2011

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Article

Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer

Sunwoo Lee, Taejeong Oh, Hyuncheol Chung, Sunyoung Rha, Changjin Kim, Youngho Moon, Benjamin D. Hoehn, Dongjun Jeong, Seunghoon Lee, Namkyu Kim, Chanhee Park, Miae Yoo, SungWhan An
Pages: 889-898
Published online on: 25 October 2011

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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