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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2005 Volume 14 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Do cancer cells selectively mutate HFE to increase their intracellular iron?

Claudia I. Müller, Carl W. Miller, Hiroshi Kawabata, Robert J. McKenna, Alberto M. Marchevsky, H. Phillip Koeffler
Pages: 299-303
Published online on: 01 August 2005

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Article

EGFR activity in HER-2 over-expressing metastatic breast cancer: evidence for simultaneous phosphorylation of Her-2/neu and EGFR

Daphne Gschwantler-Kaulich, Gernot Hudelist, Wolfgang J. Koestler, Klaus Czerwenka, Ruth Mueller, Samir Helmy, Ernst Ruecklinger, Ernst Kubista, Christian F. Singer
Pages: 305-311
Published online on: 01 August 2005

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Article

ATM expression in rectal cancers with or without preoperative radiotherapy

Linda Ärlehag, Gunnar Adell, Annica Knutsen, Sten Thorstenson, Xiao-Feng Sun
Pages: 313-317
Published online on: 01 August 2005

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Article

Molecular clonal analysis of recurrent bladder cancer

Kerstin Junker, Michael Wolf, Jörg Schubert
Pages: 319-323
Published online on: 01 August 2005

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Article

Connexins 26 and 43 correlate with Bak, but not with Bcl-2 protein in breast cancer

Luiza Kanczuga-Koda, Stanislaw Sulkowski, Jakub Tomaszewski, Mariusz Koda, Mariola Sulkowska, Wojciech Przystupa, Jolanta Golaszewska, Marek Baltaziak
Pages: 325-329
Published online on: 01 August 2005

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Article

The activities of thymidine phosphorylase and dihydropyrimidine dehydrogenase in colorectal cancer depend on where the sample is taken

Masaichi Ogawa, Kenji Ikeuchi, Yoshihiko Takao, Tetsuya Kobayashi, Ken Eto, Takurou Ushigome, Michiaki Watanabe, Sadao Anazawa, Yoji Yamazaki, Katsuhiko Yanaga
Pages: 331-335
Published online on: 01 August 2005

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Article

Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression: Gene amplification does not contribute to EGFR expression

Shinobu Umemura, Susumu Takekoshi, Yasuhiro Suzuki, Yuki Saitoh, Yutaka Tokuda, R. Yoshiyuki Osamura
Pages: 337-343
Published online on: 01 August 2005

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Article

Suppression of β-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats

Akira Hara, Keiko Sakata, Yasuhiro Yamada, Toshiya Kuno, Nami Kitaori, Takeru Oyama, Yoshinobu Hirose, Akira Murakami, Takuji Tanaka, Hideki Mori
Pages: 345-351
Published online on: 01 August 2005

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Article

Prognostic significance of CD83 positive, mature dendritic cells in the gallbladder carcinoma

Makoto Furihata, Yuko Ono, Kazuhito Ichikawa, Shigeki Tomita, Takahiro Fujimori, Keiichi Kubota
Pages: 353-356
Published online on: 01 August 2005

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Article

Clinical significance of the expression of tumor-associated antigen, RCAS1, and its soluble protein in pleural fluid in malignant mesothelioma

Akio Hiraki, Keisuke Aoe, Tomoyuki Murakami, Yuichi Nakamura, Koich Yamazaki, Naoko Sueoka, Koji Taguchi, Toshiaki Kamei, Tadashi Maeda, Hiroyasu Takeyama, Takumi Kishimoto, Masaharu Nishimura, Kazuro Sugi
Pages: 357-362
Published online on: 01 August 2005

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Article

Clinical significance of p21WAF1/CIP1 and p53 expression in serous cystadenocarcinoma of the ovary

Fumitoshi Terauchi, Aikou Okamoto, Takeo Nagashima, Yukari Kobayashi, Tetsuya Moritake, Yasuhiro Yamamoto, Satoshi Takakura, Satoko Iwaki, Hisao Ogura
Pages: 363-368
Published online on: 01 August 2005

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Article

Prognostic value of CD83-positive mature dendritic cells and their relation to vascular endothelial growth factor in advanced human gastric cancer

Shoichi Tsukayama, Kenji Omura, Koichi Yoshida, Yoko Tanaka, Go Watanabe
Pages: 369-375
Published online on: 01 August 2005

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Article

Suppression of chemically-induced liver tumors by castration or estradiol-3-benzoate treatment in F344 rats

Jin Seok Kang, Byeongwoo Ahn, Chuel Kyu Kim, Beom Seok Han, Jeong-Hwan Che, Seyl Kim, Dong Deuk Jang, Ki-Hwa Yang
Pages: 377-382
Published online on: 01 August 2005

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Article

Growth effect of gastrin on gastric cancer and its clinical implications for gastric cancer surgery

Hyeon Kook Lee, Hyuk-Joon Lee, Keun Hur, Hye Seung Lee, Woo Ho Kim, Dov Michaeli, Kuk Jin Choe, Han-Kwang Yang
Pages: 383-388
Published online on: 01 August 2005

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Article

PTEN-positive and phosphorylated-Akt-negative expression is a predictor of survival for patients with advanced endometrial carcinoma

Kazunori Uegaki, Yasunobu Kanamori, Junzo Kigawa, Wakae Kawaguchi, Ruri Kaneko, Jun Naniwa, Masakuni Takahashi, Muneaki Shimada, Tetsuro Oishi, Hiroaki Itamochi, Naoki Terakawa
Pages: 389-392
Published online on: 01 August 2005

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Article

Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells

Shin-ichiro Masunaga, Hideko Nagasawa, Yoshihiro Uto, Hitoshi Hori, Ken Ohnishi, Akihisa Takahashi, Takeo Ohnishi, Minoru Suzuki, Kenji Nagata, Yuko Kinashi, Koji Ono
Pages: 393-400
Published online on: 01 August 2005

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Article

Phase II study on low dose gemcitabine plus oral chemotherapy with uracil-tegafur and cyclophosphamide in combination with radiotherapy against recurrent and advanced pancreatic cancer

Yoshinori Nio, Koji Hashimoto, Seiji Yano, Masayuki Itakura, Makoto Koike, Kazushige Yamaguchi, Shinichiro Endo, Munechika Tsuji, Tetsuya Higami, Riruke Maruyama
Pages: 401-408
Published online on: 01 August 2005

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Article

Suppression of glutathione S-transferase placental form-positive foci development in rat hepatocarcinogenesis by Chlorella pyrenoidosa

Hideo Takekoshi, Toru Mizoguchi, Yoko Komasa, Hirofumi Chubachi, Yukari Inoue, Hideyo Imanishi, Masuo Nakano
Pages: 409-414
Published online on: 01 August 2005

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Article

FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer

Monica Spinola, Vera Piera Leoni, Jun-ichi Tanuma, Angela Pettinicchio, Milo Frattini, Stefano Signoroni, Roberto Agresti, Riccardo Giovanazzi, Silvana Pilotti, Lucio Bertario, Fernando Ravagnani, Tommaso A. Dragani
Pages: 415-419
Published online on: 01 August 2005

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Article

The modifier subunit of glutamate cysteine ligase relates to cisplatin resistance in human small cell lung cancer xenografts in vivo

Masatake Nishi, Yoshiyuki Abe, Sakashi Fujimori, Atsushi Hamamoto, Yoshimasa Inoue, Noriyuki Miyazaki, Yasuhisa Oida, Norihiro Ikoma, Yasuyuki Ohnishi, Hitoshi Yamazaki, Yoshito Ueyama, Masato Nakamura
Pages: 421-424
Published online on: 01 August 2005

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Article

Macrophage infiltration and its prognostic implications in breast cancer: The relationship with VEGF expression and microvessel density

Shinichi Tsutsui, Kazuhiro Yasuda, Kosuke Suzuki, Kouichirou Tahara, Hidefumi Higashi, Shoichi Era
Pages: 425-431
Published online on: 01 August 2005

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Article

Toxicity during l-LV/5FU adjuvant chemotherapy as a modified RPMI regimen for patients with colorectal cancer

Tsukasa Hotta, Katsunari Takifuji, Kazuo Arii, Shozo Yokoyama, Kenji Matsuda, Takashi Higashiguchi, Toshiji Tominaga, Yoshimasa Oku, Hiroki Yamaue
Pages: 433-439
Published online on: 01 August 2005

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Article

Analysis of gene expression during staurosporine-induced neuronal differentiation of human prostate cancer cells

Takahisa Shimizu, Akiko Okayama, Toshihiro Inoue, Ken Takeda
Pages: 441-448
Published online on: 01 August 2005

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Article

Reduced syndecan-1 expression stimulates heparin-binding growth factor-mediated invasion in ovarian cancer cells in a urokinase-independent mechanism

Hidenori Matsuzaki, Hiroshi Kobayashi, Tatsuo Yagyu, Kiyoshi Wakahara, Toshiharu Kondo, Noriyuki Kurita, Hideo Sekino, Kiyokazu Inagaki, Mika Suzuki, Naohiro Kanayama, Toshihiko Terao
Pages: 449-457
Published online on: 01 August 2005

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Article

Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women

Yong Beom Kim, Yong Sang Song, Yong Tark Jeon, Jong Sup Park, Soo Jong Um, Jae Weon Kim, Noh Hyun Park, Soon Beom Kang, Hyo Pyo Lee
Pages: 459-464
Published online on: 01 August 2005

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Article

A single nucleotide polymorphism in the extracellular domain of TRAIL receptor DR4 at nucleotide 626 in gastric cancer patients in Japan

Kazuya Kuraoka, Shunji Matsumura, Yuichi Sanada, Kei Nakachi, Kazue Imai, Hidetaka Eguchi, Keisuke Matsusaki, Naohide Oue, Hirofumi Nakayama, Wataru Yasui
Pages: 465-470
Published online on: 01 August 2005

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Article

Loss of heterozygosity at 17p13.3-ter, distal to TP53, correlates with negative hormonal phenotype in sporadic breast cancer

Laura Roncuzzi, Irene Brognara, Daniela Baiocchi, Dino Amadori, Anna Gasperi-Campani
Pages: 471-474
Published online on: 01 August 2005

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Article

Induction of apoptosis by Chan Su, a traditional Chinese medicine, in human bladder carcinoma T24 cells

Woo Shin Ko, Tae Yeol Park, Cheol Park, Young Hee Kim, Hwa Jung Yoon, Seung Yeon Lee, Sang Hoon Hong, Byung Tae Choi, Yong Tae Lee, Yung Hyun Choi
Pages: 475-480
Published online on: 01 August 2005

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Article

Docetaxel plus epirubicin as first-line chemotherapy in MBC (KCSG 01-10-05): Phase II trial and the predictive values of circulating HER2 extracellular domain and vascular endothelial growth factor

Seock-Ah Im, Sung-Bae Kim, Moon Hee Lee, Young-Hyuck Im, Kyung Hee Lee, Hong-Suk Song, Myung-Ah Lee, Junglim Lee, Nam-Su Lee, Hae Sun Ham, Tae-You Kim, Yeon Hee Park, Kyung Eun Lee, Kee Won Kim, Jae Hong Seo, Soon Nam Lee, Young Seon Hong, Yung-Jue Bang, Woo-Kun Kim, Hee-Sook Park
Pages: 481-487
Published online on: 01 August 2005

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Article

Antineoplaston induces G1 arrest by PKCα and MAPK pathway in SKBR-3 breast cancer cells

Teruhiko Fujii, Anna M. Nakamura, Goro Yokoyama, Miki Yamaguchi, Kosuke Tayama, Keisuke Miwa, Uhi Toh, Daisuke Kawamura, Kazuo Shirouzu, Hideaki Yamana, Michihiko Kuwano, Hideaki Tsuda
Pages: 489-494
Published online on: 01 August 2005

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Article

Functional analysis of transactivation by mutants of hepatitis B virus X gene in human hepatocellular carcinoma

Masami Minemura, Yukihiro Shimizu, Katsuharu Hirano, Yasuhiro Nakayama, Yoshiharu Tokimitsu, Kazuto Tajiri, Kazuki Yamada, Feng Xue, Terumi Takahara, Akiharu Watanabe, Toshiro Sugiyama
Pages: 495-499
Published online on: 01 August 2005

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Article

Cyclic polylactate inhibited growth of cloned leukemic cells through reducing glycolytic enzyme activities

Tomonori Harada, Masaya Nagasu, Isao Tsuboi, Morimichi Koshinaga, Hitoshi Kanno, Shin Aizawa
Pages: 501-505
Published online on: 01 August 2005

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Article

Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells

Yumiko Achiwa, Kiyoshi Hasegawa, Yasuhiro Udagawa
Pages: 507-512
Published online on: 01 August 2005

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Article

Prognostic significance of a combined clinicopathologic score for response to primary systemic therapy in locally advanced breast cancer

Philippe Bertheau, Florence Lerebours, Nicolas Mounier, Anne de Roquancourt, Marc Espié, Philippe Clot, Jean-Marie Servant, Jean-Louis Misset, Michel Marty, Anne Janin
Pages: 513-520
Published online on: 01 August 2005

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Article

Is adjuvant radiotherapy in early stages (FIGO I-II) of epithelial ovarian cancer a treatment of the past?

Ingiridur Skirnisdottir, Sarah Nordqvist, Bengt Sorbe
Pages: 521-529
Published online on: 01 August 2005

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Article

Characterization of estrogen-induced F-box protein FBXO45

Kenichi Yoshida
Pages: 531-535
Published online on: 01 August 2005

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Article

Clinical evaluation of a panel of mRNA markers in the detection of disseminated tumor cells in patients with operable breast cancer

Mario Varangot, Enrique Barrios, Cecilia Sóñora, Bernardo Aizen, Carlos Pressa, Roberto Estrugo, Raúl Lavigna, Ignacio Musé, Eduardo Osinaga, Nora Berois
Pages: 537-545
Published online on: 01 August 2005

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Article

In silico characterization of LZTS3, a potential tumor suppressor

Andreas Teufel, Arndt Weinmann, Peter R. Galle, Ansgar W. Lohse
Pages: 547-551
Published online on: 01 August 2005

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Article

Optimization of PKH67 labeling conditions for proliferation monitoring in daunorubicin-treated leukemic cells

M. Barbier, H. Morjani, K.A. Muirhead, X. Ronot, J. Boutonnat
Pages: 553-559
Published online on: 01 August 2005

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Article

Effect of hyperthermia on uptake and cytotoxicity of cisplatin in cultured murine mammary carcinoma cells

J. Haveman, J. W.J. Bergs, N. A.P. Franken, C. van Bree, L. J.A. Stalpers
Pages: 561-567
Published online on: 01 August 2005

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Article

Polymorphisms in the DNA methyltransferase 3b gene and prostate cancer risk

Rakesh Singal, Partha M. Das, Murugesan Manoharan, Isildinha M. Reis, James J. Schlesselman
Pages: 569-573
Published online on: 01 August 2005

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Article

Expression of S100P protein correlates with and contributes to the tumorigenic capacity of HeLa cervical carcinoma cells

Adriana Gibadulinová, Monika Baráthová, Juraj Kopácek, Alzbeta Hulíková, Silvia Pastoreková, Richard Kettmann, Jaromír Pastorek
Pages: 575-582
Published online on: 01 August 2005

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Article

Effect of estradiol and raloxifene on MUC1 expression and adhesive properties of Ishikawa cells

Anna Paszkiewicz-Gadek, Halina Porowska, Miroslawa Pietruczuk, Jozef Haczynski, Dariusz G. Kisiel, Slawomir Wolczynski
Pages: 583-589
Published online on: 01 August 2005

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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Article Open Access

NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Review Open Access

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Article Open Access

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1

Xiaobai Hao, Yu Chen
Article Number: 102
Published online on: 24 March 2026

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Article Open Access

MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells

Rui Luo, Jingping Chen, Zhaojie Chen, Surong Wang, Tianfeng Liu, Yang Xu
Article Number: 101
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation

Wanzhi Chen, Jichun Yu, Rong Xie, Tao Zhou, Chengfeng Xiong, Shuyong Zhang, Meijun Zhong
Article Number: 100
Published online on: 23 March 2026

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Andrographis exerts antitumor effects and enhances 5‑FU efficacy via the alteration of ferroptosis‑related genes in esophageal squamous cell carcinoma

Kosuke Yoshimura, Tadanobu Shimura, Ruiya Ma, Yaxuan Huang, Takahito Kitajima, Shinji Yamashita, Yuki Sato, Koki Higashi, Mikio Kawamura, Hiromi Yasuda, Yuhki Koike, Yoshiki Okita, Shigeyuki Yoshiyama, Minako Kobayashi, Masaki Ohi, Hiroki Ohge, Shinya Takahashi, Ajay Goel, Yoshinaga Okugawa, Yuji Toiyama
Article Number: 99
Published online on: 20 March 2026

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Sphingosine‑1‑phosphate receptor 1 enhances olfactory receptor 51E1‑mediated inhibition of proliferation via Src/JNK signaling in prostate cancer cells

Kiheon Kim, Jinwoo Lee, Chulwon Choi, Jungnam Bae, Hee-Jung Choi, Won-Ki Huh
Article Number: 98
Published online on: 19 March 2026

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Mechanistic insights into the roles of astragalosides and Astragalus polysaccharides in gynecological and breast cancers (Review)

Ruixin Liu, Zhanyu Lin, Yuelin Li, Yuetong Ci, Zhengqi Guo, Zhenguo Xu
Article Number: 97
Published online on: 19 March 2026

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Retraction Open Access

[Retracted] Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors 

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Article Number: 96
Published online on: 16 March 2026

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Silencing of SIVA‑1 promotes cisplatin resistance in gastric cancer via the Bcl‑2/BAX‑mediated mitochondria‑dependent apoptosis pathway

Zheng-Yi Shi, Zheng-Rong Ding, Yu-Liang Huang, Yuan-Rui Lei, Hai-Bin Huang, Yan Qing, Miao-Ren Deng, Xu-Man Lu, Xu-Dong Dong, Long-Jie Xia, Sheng Xu, Xiao-Gang Zhong, Lei Li, Fan-Biao Kong, Xiao-Tong Wang
Article Number: 95
Published online on: 13 March 2026

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Depleting HIF‑1α attenuates the progression of osteosarcoma, but tumorigenicity is sustained through HIF‑independent pathways

Ayaka Kunishima, Takatsune Shimizu, Tetsuya Takimoto, Atsunobu Sagara, Hiroyuki Nobusue, Hidetoshi Hasuwa, Shinya Hasegawa, Yuka Tamaoki, Hitomi Miyake, Yumi Fukuchi, Hideyuki Saya, Akihiro Muto
Article Number: 94
Published online on: 12 March 2026

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Article Open Access

Unveiling the role of ANGPT2 in esophageal cancer: A prognostic factor and potential oncogene

Zhigang Zhai, Zhenyu Xue, Yuan Fang, Yixu Fan, Shijiao Li, Yunpeng Yu, Chuansheng Chen, Kaijun Zhang, Deyu Chen, Xiang Tang, Rui Ling
Article Number: 93
Published online on: 12 March 2026

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Article Open Access

POLQ promotes tumor progression and immunosuppression via ATM‑P53 signaling in endometrial cancer

Ningning Zhu, Juanjuan Wang, Xiaoli Zhang, Kai Tang, Lei Gong, Yi Hu
Article Number: 92
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial‑mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Article Number: 91
Published online on: 11 March 2026

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Review Open Access

Unveiling the molecular landscape: Long non-coding RNAs in neuroblastoma (Review)

Zidong Xia, Huishan Zhai, Lei Zheng, Cheng Wang
Article Number: 90
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu
Article Number: 89
Published online on: 09 March 2026

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Review Open Access

Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review)

Junlun Liu, Danyu Li, Chao Li, Zhuoren Chen
Article Number: 88
Published online on: 06 March 2026

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma 

Lei You, Xiaoxia Ren, Yongxing Du, Wenjing Zhao, Ming Cui, Ge Chen, Yupei Zhao
Article Number: 87
Published online on: 05 March 2026

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Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held-Feindt
Article Number: 85
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Article Open Access

Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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Article Open Access

ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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