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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2005 Volume 14 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Do cancer cells selectively mutate HFE to increase their intracellular iron?

Claudia I. Müller, Carl W. Miller, Hiroshi Kawabata, Robert J. McKenna, Alberto M. Marchevsky, H. Phillip Koeffler
Pages: 299-303
Published online on: 01 August 2005

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Article

EGFR activity in HER-2 over-expressing metastatic breast cancer: evidence for simultaneous phosphorylation of Her-2/neu and EGFR

Daphne Gschwantler-Kaulich, Gernot Hudelist, Wolfgang J. Koestler, Klaus Czerwenka, Ruth Mueller, Samir Helmy, Ernst Ruecklinger, Ernst Kubista, Christian F. Singer
Pages: 305-311
Published online on: 01 August 2005

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Article

ATM expression in rectal cancers with or without preoperative radiotherapy

Linda Ärlehag, Gunnar Adell, Annica Knutsen, Sten Thorstenson, Xiao-Feng Sun
Pages: 313-317
Published online on: 01 August 2005

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Article

Molecular clonal analysis of recurrent bladder cancer

Kerstin Junker, Michael Wolf, Jörg Schubert
Pages: 319-323
Published online on: 01 August 2005

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Article

Connexins 26 and 43 correlate with Bak, but not with Bcl-2 protein in breast cancer

Luiza Kanczuga-Koda, Stanislaw Sulkowski, Jakub Tomaszewski, Mariusz Koda, Mariola Sulkowska, Wojciech Przystupa, Jolanta Golaszewska, Marek Baltaziak
Pages: 325-329
Published online on: 01 August 2005

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Article

The activities of thymidine phosphorylase and dihydropyrimidine dehydrogenase in colorectal cancer depend on where the sample is taken

Masaichi Ogawa, Kenji Ikeuchi, Yoshihiko Takao, Tetsuya Kobayashi, Ken Eto, Takurou Ushigome, Michiaki Watanabe, Sadao Anazawa, Yoji Yamazaki, Katsuhiko Yanaga
Pages: 331-335
Published online on: 01 August 2005

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Article

Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression: Gene amplification does not contribute to EGFR expression

Shinobu Umemura, Susumu Takekoshi, Yasuhiro Suzuki, Yuki Saitoh, Yutaka Tokuda, R. Yoshiyuki Osamura
Pages: 337-343
Published online on: 01 August 2005

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Article

Suppression of β-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats

Akira Hara, Keiko Sakata, Yasuhiro Yamada, Toshiya Kuno, Nami Kitaori, Takeru Oyama, Yoshinobu Hirose, Akira Murakami, Takuji Tanaka, Hideki Mori
Pages: 345-351
Published online on: 01 August 2005

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Article

Prognostic significance of CD83 positive, mature dendritic cells in the gallbladder carcinoma

Makoto Furihata, Yuko Ono, Kazuhito Ichikawa, Shigeki Tomita, Takahiro Fujimori, Keiichi Kubota
Pages: 353-356
Published online on: 01 August 2005

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Article

Clinical significance of the expression of tumor-associated antigen, RCAS1, and its soluble protein in pleural fluid in malignant mesothelioma

Akio Hiraki, Keisuke Aoe, Tomoyuki Murakami, Yuichi Nakamura, Koich Yamazaki, Naoko Sueoka, Koji Taguchi, Toshiaki Kamei, Tadashi Maeda, Hiroyasu Takeyama, Takumi Kishimoto, Masaharu Nishimura, Kazuro Sugi
Pages: 357-362
Published online on: 01 August 2005

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Article

Clinical significance of p21WAF1/CIP1 and p53 expression in serous cystadenocarcinoma of the ovary

Fumitoshi Terauchi, Aikou Okamoto, Takeo Nagashima, Yukari Kobayashi, Tetsuya Moritake, Yasuhiro Yamamoto, Satoshi Takakura, Satoko Iwaki, Hisao Ogura
Pages: 363-368
Published online on: 01 August 2005

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Article

Prognostic value of CD83-positive mature dendritic cells and their relation to vascular endothelial growth factor in advanced human gastric cancer

Shoichi Tsukayama, Kenji Omura, Koichi Yoshida, Yoko Tanaka, Go Watanabe
Pages: 369-375
Published online on: 01 August 2005

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Article

Suppression of chemically-induced liver tumors by castration or estradiol-3-benzoate treatment in F344 rats

Jin Seok Kang, Byeongwoo Ahn, Chuel Kyu Kim, Beom Seok Han, Jeong-Hwan Che, Seyl Kim, Dong Deuk Jang, Ki-Hwa Yang
Pages: 377-382
Published online on: 01 August 2005

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Article

Growth effect of gastrin on gastric cancer and its clinical implications for gastric cancer surgery

Hyeon Kook Lee, Hyuk-Joon Lee, Keun Hur, Hye Seung Lee, Woo Ho Kim, Dov Michaeli, Kuk Jin Choe, Han-Kwang Yang
Pages: 383-388
Published online on: 01 August 2005

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Article

PTEN-positive and phosphorylated-Akt-negative expression is a predictor of survival for patients with advanced endometrial carcinoma

Kazunori Uegaki, Yasunobu Kanamori, Junzo Kigawa, Wakae Kawaguchi, Ruri Kaneko, Jun Naniwa, Masakuni Takahashi, Muneaki Shimada, Tetsuro Oishi, Hiroaki Itamochi, Naoki Terakawa
Pages: 389-392
Published online on: 01 August 2005

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Article

Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells

Shin-ichiro Masunaga, Hideko Nagasawa, Yoshihiro Uto, Hitoshi Hori, Ken Ohnishi, Akihisa Takahashi, Takeo Ohnishi, Minoru Suzuki, Kenji Nagata, Yuko Kinashi, Koji Ono
Pages: 393-400
Published online on: 01 August 2005

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Article

Phase II study on low dose gemcitabine plus oral chemotherapy with uracil-tegafur and cyclophosphamide in combination with radiotherapy against recurrent and advanced pancreatic cancer

Yoshinori Nio, Koji Hashimoto, Seiji Yano, Masayuki Itakura, Makoto Koike, Kazushige Yamaguchi, Shinichiro Endo, Munechika Tsuji, Tetsuya Higami, Riruke Maruyama
Pages: 401-408
Published online on: 01 August 2005

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Article

Suppression of glutathione S-transferase placental form-positive foci development in rat hepatocarcinogenesis by Chlorella pyrenoidosa

Hideo Takekoshi, Toru Mizoguchi, Yoko Komasa, Hirofumi Chubachi, Yukari Inoue, Hideyo Imanishi, Masuo Nakano
Pages: 409-414
Published online on: 01 August 2005

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Article

FGFR4 Gly388Arg polymorphism and prognosis of breast and colorectal cancer

Monica Spinola, Vera Piera Leoni, Jun-ichi Tanuma, Angela Pettinicchio, Milo Frattini, Stefano Signoroni, Roberto Agresti, Riccardo Giovanazzi, Silvana Pilotti, Lucio Bertario, Fernando Ravagnani, Tommaso A. Dragani
Pages: 415-419
Published online on: 01 August 2005

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Article

The modifier subunit of glutamate cysteine ligase relates to cisplatin resistance in human small cell lung cancer xenografts in vivo

Masatake Nishi, Yoshiyuki Abe, Sakashi Fujimori, Atsushi Hamamoto, Yoshimasa Inoue, Noriyuki Miyazaki, Yasuhisa Oida, Norihiro Ikoma, Yasuyuki Ohnishi, Hitoshi Yamazaki, Yoshito Ueyama, Masato Nakamura
Pages: 421-424
Published online on: 01 August 2005

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Article

Macrophage infiltration and its prognostic implications in breast cancer: The relationship with VEGF expression and microvessel density

Shinichi Tsutsui, Kazuhiro Yasuda, Kosuke Suzuki, Kouichirou Tahara, Hidefumi Higashi, Shoichi Era
Pages: 425-431
Published online on: 01 August 2005

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Article

Toxicity during l-LV/5FU adjuvant chemotherapy as a modified RPMI regimen for patients with colorectal cancer

Tsukasa Hotta, Katsunari Takifuji, Kazuo Arii, Shozo Yokoyama, Kenji Matsuda, Takashi Higashiguchi, Toshiji Tominaga, Yoshimasa Oku, Hiroki Yamaue
Pages: 433-439
Published online on: 01 August 2005

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Article

Analysis of gene expression during staurosporine-induced neuronal differentiation of human prostate cancer cells

Takahisa Shimizu, Akiko Okayama, Toshihiro Inoue, Ken Takeda
Pages: 441-448
Published online on: 01 August 2005

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Article

Reduced syndecan-1 expression stimulates heparin-binding growth factor-mediated invasion in ovarian cancer cells in a urokinase-independent mechanism

Hidenori Matsuzaki, Hiroshi Kobayashi, Tatsuo Yagyu, Kiyoshi Wakahara, Toshiharu Kondo, Noriyuki Kurita, Hideo Sekino, Kiyokazu Inagaki, Mika Suzuki, Naohiro Kanayama, Toshihiko Terao
Pages: 449-457
Published online on: 01 August 2005

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Article

Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women

Yong Beom Kim, Yong Sang Song, Yong Tark Jeon, Jong Sup Park, Soo Jong Um, Jae Weon Kim, Noh Hyun Park, Soon Beom Kang, Hyo Pyo Lee
Pages: 459-464
Published online on: 01 August 2005

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Article

A single nucleotide polymorphism in the extracellular domain of TRAIL receptor DR4 at nucleotide 626 in gastric cancer patients in Japan

Kazuya Kuraoka, Shunji Matsumura, Yuichi Sanada, Kei Nakachi, Kazue Imai, Hidetaka Eguchi, Keisuke Matsusaki, Naohide Oue, Hirofumi Nakayama, Wataru Yasui
Pages: 465-470
Published online on: 01 August 2005

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Article

Loss of heterozygosity at 17p13.3-ter, distal to TP53, correlates with negative hormonal phenotype in sporadic breast cancer

Laura Roncuzzi, Irene Brognara, Daniela Baiocchi, Dino Amadori, Anna Gasperi-Campani
Pages: 471-474
Published online on: 01 August 2005

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Article

Induction of apoptosis by Chan Su, a traditional Chinese medicine, in human bladder carcinoma T24 cells

Woo Shin Ko, Tae Yeol Park, Cheol Park, Young Hee Kim, Hwa Jung Yoon, Seung Yeon Lee, Sang Hoon Hong, Byung Tae Choi, Yong Tae Lee, Yung Hyun Choi
Pages: 475-480
Published online on: 01 August 2005

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Article

Docetaxel plus epirubicin as first-line chemotherapy in MBC (KCSG 01-10-05): Phase II trial and the predictive values of circulating HER2 extracellular domain and vascular endothelial growth factor

Seock-Ah Im, Sung-Bae Kim, Moon Hee Lee, Young-Hyuck Im, Kyung Hee Lee, Hong-Suk Song, Myung-Ah Lee, Junglim Lee, Nam-Su Lee, Hae Sun Ham, Tae-You Kim, Yeon Hee Park, Kyung Eun Lee, Kee Won Kim, Jae Hong Seo, Soon Nam Lee, Young Seon Hong, Yung-Jue Bang, Woo-Kun Kim, Hee-Sook Park
Pages: 481-487
Published online on: 01 August 2005

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Article

Antineoplaston induces G1 arrest by PKCα and MAPK pathway in SKBR-3 breast cancer cells

Teruhiko Fujii, Anna M. Nakamura, Goro Yokoyama, Miki Yamaguchi, Kosuke Tayama, Keisuke Miwa, Uhi Toh, Daisuke Kawamura, Kazuo Shirouzu, Hideaki Yamana, Michihiko Kuwano, Hideaki Tsuda
Pages: 489-494
Published online on: 01 August 2005

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Article

Functional analysis of transactivation by mutants of hepatitis B virus X gene in human hepatocellular carcinoma

Masami Minemura, Yukihiro Shimizu, Katsuharu Hirano, Yasuhiro Nakayama, Yoshiharu Tokimitsu, Kazuto Tajiri, Kazuki Yamada, Feng Xue, Terumi Takahara, Akiharu Watanabe, Toshiro Sugiyama
Pages: 495-499
Published online on: 01 August 2005

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Article

Cyclic polylactate inhibited growth of cloned leukemic cells through reducing glycolytic enzyme activities

Tomonori Harada, Masaya Nagasu, Isao Tsuboi, Morimichi Koshinaga, Hitoshi Kanno, Shin Aizawa
Pages: 501-505
Published online on: 01 August 2005

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Article

Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells

Yumiko Achiwa, Kiyoshi Hasegawa, Yasuhiro Udagawa
Pages: 507-512
Published online on: 01 August 2005

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Article

Prognostic significance of a combined clinicopathologic score for response to primary systemic therapy in locally advanced breast cancer

Philippe Bertheau, Florence Lerebours, Nicolas Mounier, Anne de Roquancourt, Marc Espié, Philippe Clot, Jean-Marie Servant, Jean-Louis Misset, Michel Marty, Anne Janin
Pages: 513-520
Published online on: 01 August 2005

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Article

Is adjuvant radiotherapy in early stages (FIGO I-II) of epithelial ovarian cancer a treatment of the past?

Ingiridur Skirnisdottir, Sarah Nordqvist, Bengt Sorbe
Pages: 521-529
Published online on: 01 August 2005

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Article

Characterization of estrogen-induced F-box protein FBXO45

Kenichi Yoshida
Pages: 531-535
Published online on: 01 August 2005

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Article

Clinical evaluation of a panel of mRNA markers in the detection of disseminated tumor cells in patients with operable breast cancer

Mario Varangot, Enrique Barrios, Cecilia Sóñora, Bernardo Aizen, Carlos Pressa, Roberto Estrugo, Raúl Lavigna, Ignacio Musé, Eduardo Osinaga, Nora Berois
Pages: 537-545
Published online on: 01 August 2005

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Article

In silico characterization of LZTS3, a potential tumor suppressor

Andreas Teufel, Arndt Weinmann, Peter R. Galle, Ansgar W. Lohse
Pages: 547-551
Published online on: 01 August 2005

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Article

Optimization of PKH67 labeling conditions for proliferation monitoring in daunorubicin-treated leukemic cells

M. Barbier, H. Morjani, K.A. Muirhead, X. Ronot, J. Boutonnat
Pages: 553-559
Published online on: 01 August 2005

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Article

Effect of hyperthermia on uptake and cytotoxicity of cisplatin in cultured murine mammary carcinoma cells

J. Haveman, J. W.J. Bergs, N. A.P. Franken, C. van Bree, L. J.A. Stalpers
Pages: 561-567
Published online on: 01 August 2005

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Article

Polymorphisms in the DNA methyltransferase 3b gene and prostate cancer risk

Rakesh Singal, Partha M. Das, Murugesan Manoharan, Isildinha M. Reis, James J. Schlesselman
Pages: 569-573
Published online on: 01 August 2005

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Article

Expression of S100P protein correlates with and contributes to the tumorigenic capacity of HeLa cervical carcinoma cells

Adriana Gibadulinová, Monika Baráthová, Juraj Kopácek, Alzbeta Hulíková, Silvia Pastoreková, Richard Kettmann, Jaromír Pastorek
Pages: 575-582
Published online on: 01 August 2005

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Article

Effect of estradiol and raloxifene on MUC1 expression and adhesive properties of Ishikawa cells

Anna Paszkiewicz-Gadek, Halina Porowska, Miroslawa Pietruczuk, Jozef Haczynski, Dariusz G. Kisiel, Slawomir Wolczynski
Pages: 583-589
Published online on: 01 August 2005

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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