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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2005 Volume 14 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis

M. Waheed Roomi, Nusrath Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 807-815
Published online on: 01 October 2005

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Article

Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines

Masashi Yanada, Takeshi Yaoi, Junichi Shimada, Chouhei Sakakura, Motohiro Nishimura, Kazuhiro Ito, Kunihiko Terauchi, Katsuhiko Nishiyama, Kyoko Itoh, Shinji Fushiki
Pages: 817-822
Published online on: 01 October 2005

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Article

Growth factor-mediated interaction between tumor cells and stromal fibroblasts in an experimental model of human small-cell lung cancer

Takaaki Sugimoto, Yuichi Takiguchi, Katsushi Kurosu, Yasunori Kasahara, Nobuhiro Tanabe, Koichiro Tatsumi, Kenzo Hiroshima, Masako Minamihisamatsu, Tadaaki Miyamoto, Takayuki Kuriyama
Pages: 823-830
Published online on: 01 October 2005

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Article

Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells

Ling Yu, Hisanori Takenobu, Osamu Shimozato, Kiyoko Kawamura, Yoshinori Nimura, Naohiko Seki, Katsuhiro Uzawa, Hideki Tanzawa, Hideaki Shimada, Takenori Ochiai, Masatoshi Tagawa
Pages: 831-835
Published online on: 01 October 2005

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Article

Loss of p21WAF1/CIP1 expression in invasive fronts of oral tongue squamous cell carcinomas is correlated with tumor progression and poor prognosis

Mitsuo Goto, Tetsuya Tsukamoto, Ken-ichi Inada, Tsutomu Mizoshita, Tetsuya Ogawa, Akihiro Terada, Ikuo Hyodo, Kazuo Shimozato, Yasuhisa Hasegawa, Masae Tatematsu
Pages: 837-846
Published online on: 01 October 2005

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Article

A role for PI3K-Akt signaling in pulmonary metastatic nodule formation of the osteosarcoma cell line, LM8

Yasushi Fukaya, Naoki Ishiguro, Takeshi Senga, Yasukatsu Ichigotani, Yasuyoshi Sohara, Motomu Tsutsui, Tomone Shioura, Takashi Iwamoto, Michinari Hamaguchi
Pages: 847-852
Published online on: 01 October 2005

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Article

Positron emission tomography elucidates transport system and tumor proliferation in meningiomas

Mamoru Murakami, Yoshio Imahori, Satoshi Kimura, Kazunori Tatsuzawa, Kei Ohwada, Yasuo Inoue, Hiroyasu Sasajima, Katsuyoshi Mineura
Pages: 853-859
Published online on: 01 October 2005

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Article

Clinical usefulness of serum and immunohistochemical markers in patients with stage Ia and Ic ovarian cancer

Toshinari Muramatsu, Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Eri Nagase, Masae Ikeda, Ken-ichi Goya, Masako Shida, Takeshi Hirasawa, Masaru Murakami, Takao Shinozuka
Pages: 861-865
Published online on: 01 October 2005

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Article

Distinct chromosomal aberrations of ampulla of Vater and pancreatic head cancers detected by laser capture microdissection and comparative genomic hybridization

Ming-Chu Chang, Yu-Ting Chang, Yu-Wen Tien, Chia-Tung Sun, Ming-Shiang Wu, Jaw-Town Lin
Pages: 867-872
Published online on: 01 October 2005

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Article

Clinical significance of MHC class II-associated invariant chain expression in human gastric carcinoma

Yasuhiro Tamori, Xiaodong Tan, Kazuhiro Nakagawa, Eiji Takai, Junji Akagi, Toshiro Kageshita, Hiroshi Egami, Michio Ogawa
Pages: 873-877
Published online on: 01 October 2005

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Article

Three novel VHL germline mutations in Korean patients with von Hippel-Lindau disease and pheochromocytomas

Hio Chung Kang, Il-Jin Kim, Jae-Hyun Park, Yong Shin, Sang-Geun Jang, Sun-A Ahn, Hye-Won Park, Sun-Kyung Lim, Seung Keun Oh, Dae Jung Kim, Kwan Woo Lee, Young-Sik Choi, Young Joo Park, Min Ro Lee, Duck-Woo Kim, Jae-Gahb Park
Pages: 879-883
Published online on: 01 October 2005

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Article

Oncoprotein expression and morphological phenotypes of human breast epithelial cells transformed by the c-Ha-ras oncogene

G. M. Calaf, M. E. Alvarado, T. K. Hei
Pages: 885-893
Published online on: 01 October 2005

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Article

Detection of circulating tumor cells from renal carcinoma patients: experiences of a two-center study

Karen Blümke, Udo Bilkenroth, Uta Schmidt, Andres Melchior, Susanne Füssel, Frank Bartel, Hans Heynemann, Paolo Fornara, Helge Taubert, Manfred P. Wirth, Axel Meye
Pages: 895-899
Published online on: 01 October 2005

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Article

Analysis of p53 status in human cell lines using a functional assay in yeast: Detection of new non-sense p53 mutation in codon 124

Jana Smardová, Sárka Pavlová, Miluska Svitáková, Diana Grochová, Barbora Ravcuková
Pages: 901-907
Published online on: 01 October 2005

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Article

Expression of HIF-1α and Glut-1 in human bladder cancer

V. Palit, R. M. Phillips, R. Puri, T. Shah, M. C. Bibby
Pages: 909-913
Published online on: 01 October 2005

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Article

Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer

Hung Trinh Viet, Dick Wågsäter, Anders Hugander, Jan Dimberg
Pages: 915-918
Published online on: 01 October 2005

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Article

A polymorphism in the 5'-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population

Toshihiko Iizasa, Masayuki Baba, Yukio Saitoh, Makoto Suzuki, Yukiko Haga, Akira Iyoda, Hao Chang, Kenzo Hiroshima, Sakae Itoga, Takeshi Tomonaga, Fumio Nomura, Takehiko Fujisawa
Pages: 919-923
Published online on: 01 October 2005

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Article

Gene expression profiling of a clonal isolate of oxaliplatin-resistant ovarian carcinoma cell line A2780/C10

Rama R. Varma, Suzanne M. Hector, Kimberly Clark, William R. Greco, Lesleyann Hawthorn, Lakshmi Pendyala
Pages: 925-932
Published online on: 01 October 2005

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Article

Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: A feasible and effective salvage treatment for lymphoid malignancies

Marino Clavio, Alberto Garrone, Ivana Pierri, Gian Luca Michelis, Manuela Balocco, Alessandra Albarello, Riccardo Varaldo, Paolo Canepa, Maurizio Miglino, Filippo Ballerini, Letizia Canepa, Marco Gobb
Pages: 933-940
Published online on: 01 October 2005

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Article

Reduced radiosensitivity and increased CD40 expression in cyclophosphamide-resistant subclones established from human cervical squamous cell carcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa, Tomoko Utsunomiya, Naohiko Umesaki
Pages: 941-948
Published online on: 01 October 2005

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Article

Radiation-induced cell death is independent of the apoptotic signals mediated by death-associated protein kinase in human cervical squamous cell carcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa, Naohiko Umesaki
Pages: 949-955
Published online on: 01 October 2005

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Article

Mechanism of cell cycle arrest by (8E,13Z,20Z)-strobilinin/(7E,13Z,20Z)-felixinin from a marine sponge Psammocinia sp.

Yahong Jiang, Eun-Young Ahn, Seung-Hee Ryu, Dong-Kyoo Kim, Jang-Su Park, Shin Won Kang, Song You, Burm-Jong Lee, Jee H. Jung
Pages: 957-962
Published online on: 01 October 2005

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Article

Alterations of the p14ARF-p53-MDM2 pathway in oral squamous cell carcinoma: MDM2 overexpression is a common event

Kue Peng Lim, Hamid Sharifah, Shin Hin Lau, Soo-Hwang Teo, Sok Ching Cheong
Pages: 963-968
Published online on: 01 October 2005

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Article

Administration of dendritic cells in cancer nodules in hepatocellular carcinoma

Teru Kumagi, S. M. Fazle Akbar, Norio Horiike, Kiyotaka Kurose, Masashi Hirooka, Atsushi Hiraoka, Yoichi Hiasa, Kojiro Michitaka, Morikazu Onji
Pages: 969-973
Published online on: 01 October 2005

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Article

5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines

Tatsuo Kanda, Motohisa Tada, Fumio Imazeki, Osamu Yokosuka, Keiichi Nagao, Hiromitsu Saisho
Pages: 975-979
Published online on: 01 October 2005

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Article

Distinct response to ionizing radiation of human prostate cell lines

Venera Cardile, Marcello Bellia, Laura Lombardo, Christian Scifo, Marcella Renis
Pages: 981-985
Published online on: 01 October 2005

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Article

Impact of orotate phosphoribosyl transferase activity as a predictor of lymph node metastasis in gastric cancer

Takumi Ochiai, Michiharu Sugitani, Kazuhiko Nishimura, Hajime Noguchi, Tsuyoshi Okada, Masakazu Ouchi, Masaki Yamada, Masayuki Kitajima, Yuko Tsuruoka, Yuka Takahashi, Shunji Futagawa
Pages: 987-992
Published online on: 01 October 2005

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Article

Expression of the inhibitors of apoptosis proteins in cisplatin-resistant prostate cancer cells

Takeo Nomura, Mutsushi Yamasaki, Yoshio Nomura, Hiromitsu Mimata
Pages: 993-997
Published online on: 01 October 2005

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Article

Clinical benefits of hepatocellular carcinoma surveillance: A single-center, hospital-based study

Naota Taura, Keisuke Hamasaki, Kazuhiko Nakao, Tatsuki Ichikawa, Daisuke Nishimura, Takashi Goto, Mariko Fukuta, Hiroshi Kawashimo, Yasuhide Motoyoshi, Hidetaka Shibata, Katsumi Eguchi
Pages: 999-1003
Published online on: 01 October 2005

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Article

DNA image cytometry on sections compared with flow cytometry in human bone metastases

David Wohlrab, Thomas Klapperstück, Hans-Jürgen Holzhausen, Andreas Held, Werner Hein
Pages: 1005-1012
Published online on: 01 October 2005

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Article

Concentration of thymidine kinase 1 in serum (S-TK1) is a more sensitive proliferation marker in human solid tumors than its activity

Qimin He, Pinggn Zhang, Li Zou, Hongxun Li, Xiuqin Wang, Shan Zhou, Tommy Fornander, Sven Skog
Pages: 1013-1019
Published online on: 01 October 2005

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Article

Prognostic impact of the detection of microcirculating tumor cells by a real-time RT-PCR assay of tyrosine hydroxylase in patients with advanced neuroblastoma

Andreu Parareda, Soledad Gallego, Josep Roma, Anna Llort, Constantino Sábado, Luis Gros, Josep Sánchez De Toledo
Pages: 1021-1027
Published online on: 01 October 2005

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Article

Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients

Isabelle Solassol, Laetitia Caumette, Françoise Bressolle, Frédéric Garcia, Simon Thézenas, Cécile Astre, Stéphane Culine, Rémi Coulouma, Frédéric Pinguet
Pages: 1029-1036
Published online on: 01 October 2005

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Article

Erythropoietic agents in anaemic patients with cancer: a retrospective observational survey of epoetin α, epoetin β and darbepoetin α use in routine clinical practice

Eric Pujade-Lauraine, Alain J. Richard, Claudine Sapède, Colin Hayward
Pages: 1037-1044
Published online on: 01 October 2005

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Article

DNA vaccines based on chimeric potyvirus-like particles carrying HPV16 E7 peptide (aa 44-60)

Dana Pokorna, Noemi Cerovska, Michal Smahel, Tomas Moravec, Viera Ludvikova, Jana Mackova, Helena Synkova, Martina Duskova, Pavel Hozak, Jiri Veleminsky
Pages: 1045-1053
Published online on: 01 October 2005

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Article

CCK2 gastrin receptor as a potential target for therapy in leukaemia cell lines

M. Stubbs, K. Khan, R. G. Wickremasinghe, K. Ganeshaguru, M. E. Caplin
Pages: 1055-1058
Published online on: 01 October 2005

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Review

Potential role of calmodulin-dependent phosphodiesterase in human brain tumor (Review)

Shankar B. Das, Rajendra K. Sharma
Pages: 1059-1063
Published online on: 01 October 2005

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Article

E-cadherin immunoreactivity correlates with recurrence and progression of minimally invasive transitional cell carcinomas of the urinary bladder

Anne Mahnken, Ingo Kausch, Alfred C. Feller, Stefan Krüger
Pages: 1065-1070
Published online on: 01 October 2005

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Article

A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma

Josephine Issakov, Yehuda Kollender, Viacheslav Soyfer, Jacob Bickels, Gideon Flusser, Isaac Meller, Ofer Merimsky
Pages: 1071-1076
Published online on: 01 October 2005

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Article

Is it reasonable to consider second-line chemotherapy in patients with hormone-refractory prostate cancer?

Karel Odrazka, Miloslava Vaculikova, Martin Dolezel, Jiri Petera, Petr Moravek, Petr Prosvic, Zdenek Zoul, Milan Vosmik, Jiri Dolezal, Eva Simakova
Pages: 1077-1081
Published online on: 01 October 2005

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Article

Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs

Masuko Katoh, Masaru Katoh
Pages: 1083-1086
Published online on: 01 October 2005

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Article

Comparative genomics on Sonic Hedgehog orthologs

Yuriko Katoh, Masaru Katoh
Pages: 1087-1090
Published online on: 01 October 2005

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Article

Relative imbalances in the expression of estrogen-metabolizing enzymes in the breast tissue of women with breast carcinoma

Seema Singh, Dhrubajyoti Chakravarti, James A. Edney, Ronald R. Hollins, Perry J. Johnson, William W. West, Sheila M. Higginbotham, Ercole L. Cavalieri, Eleanor G. Rogan
Pages: 1091-1096
Published online on: 01 October 2005

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability

An Ni Lee, Chia Chang Wu, Su Wei Hu, Chih Heng Chen, Yi Te Chiang, Wei Tang Kao, Kai Yi Tzou, Chia Hung Liu, Shao Wei Dong, Yu Ting Wang, Yueh Lin Lee, Siou Bi Li, Che An Wu, Chiao Chun Liao, Ming Hsien Chan, Po Han Chiu, Chien Hsiu Li
Article Number: 198
Published online on: 30 September 2026

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Article Open Access

Loperamide enhances the radiosensitivity of cervical cancer cells via ferroptosis induction

Huarong Guo, Haixia Li, Shunkang Tian, Yunkai Zhang, Fuyun Wu, Jing Ke
Article Number: 197
Published online on: 30 September 2026

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Review Open Access

Mitochondrial mechanisms underlying spatial immune phenotypes in non‑small cell lung cancer: Implications for ICI response and cold‑to‑hot tumor conversion (Review)

Hongyi Lai, Ke Sun, Tong Mu, Xi Liu, Mingshan Liu
Article Number: 196
Published online on: 30 September 2026

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Article Open Access

PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway

Xu Li, Yuhui Ma
Article Number: 195
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑195‑5p is a potential diagnostic and therapeutic target for breast cancer

Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Article Number: 194
Published online on: 23 September 2026

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Article Open Access

SGPP1 as a tumor suppressor in esophageal squamous cell carcinoma: Potential molecular mechanisms involving UGT1A9/UGT2B28 and clinical prognostic significance

Linlin Su, Liubing Hou, Xuetao Han, Ge Zhang, Jiayuan Li, Yu Wang, Yuxin Han, Xiaoying Xue, Huandi Zhou
Article Number: 193
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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December-2026 Volume 56 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang
Article Number: 199
Published online on: 30 September 2026

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