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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2005 Volume 14 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis

M. Waheed Roomi, Nusrath Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 807-815
Published online on: 01 October 2005

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Article

Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines

Masashi Yanada, Takeshi Yaoi, Junichi Shimada, Chouhei Sakakura, Motohiro Nishimura, Kazuhiro Ito, Kunihiko Terauchi, Katsuhiko Nishiyama, Kyoko Itoh, Shinji Fushiki
Pages: 817-822
Published online on: 01 October 2005

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Article

Growth factor-mediated interaction between tumor cells and stromal fibroblasts in an experimental model of human small-cell lung cancer

Takaaki Sugimoto, Yuichi Takiguchi, Katsushi Kurosu, Yasunori Kasahara, Nobuhiro Tanabe, Koichiro Tatsumi, Kenzo Hiroshima, Masako Minamihisamatsu, Tadaaki Miyamoto, Takayuki Kuriyama
Pages: 823-830
Published online on: 01 October 2005

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Article

Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells

Ling Yu, Hisanori Takenobu, Osamu Shimozato, Kiyoko Kawamura, Yoshinori Nimura, Naohiko Seki, Katsuhiro Uzawa, Hideki Tanzawa, Hideaki Shimada, Takenori Ochiai, Masatoshi Tagawa
Pages: 831-835
Published online on: 01 October 2005

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Article

Loss of p21WAF1/CIP1 expression in invasive fronts of oral tongue squamous cell carcinomas is correlated with tumor progression and poor prognosis

Mitsuo Goto, Tetsuya Tsukamoto, Ken-ichi Inada, Tsutomu Mizoshita, Tetsuya Ogawa, Akihiro Terada, Ikuo Hyodo, Kazuo Shimozato, Yasuhisa Hasegawa, Masae Tatematsu
Pages: 837-846
Published online on: 01 October 2005

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Article

A role for PI3K-Akt signaling in pulmonary metastatic nodule formation of the osteosarcoma cell line, LM8

Yasushi Fukaya, Naoki Ishiguro, Takeshi Senga, Yasukatsu Ichigotani, Yasuyoshi Sohara, Motomu Tsutsui, Tomone Shioura, Takashi Iwamoto, Michinari Hamaguchi
Pages: 847-852
Published online on: 01 October 2005

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Article

Positron emission tomography elucidates transport system and tumor proliferation in meningiomas

Mamoru Murakami, Yoshio Imahori, Satoshi Kimura, Kazunori Tatsuzawa, Kei Ohwada, Yasuo Inoue, Hiroyasu Sasajima, Katsuyoshi Mineura
Pages: 853-859
Published online on: 01 October 2005

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Article

Clinical usefulness of serum and immunohistochemical markers in patients with stage Ia and Ic ovarian cancer

Toshinari Muramatsu, Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Eri Nagase, Masae Ikeda, Ken-ichi Goya, Masako Shida, Takeshi Hirasawa, Masaru Murakami, Takao Shinozuka
Pages: 861-865
Published online on: 01 October 2005

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Article

Distinct chromosomal aberrations of ampulla of Vater and pancreatic head cancers detected by laser capture microdissection and comparative genomic hybridization

Ming-Chu Chang, Yu-Ting Chang, Yu-Wen Tien, Chia-Tung Sun, Ming-Shiang Wu, Jaw-Town Lin
Pages: 867-872
Published online on: 01 October 2005

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Article

Clinical significance of MHC class II-associated invariant chain expression in human gastric carcinoma

Yasuhiro Tamori, Xiaodong Tan, Kazuhiro Nakagawa, Eiji Takai, Junji Akagi, Toshiro Kageshita, Hiroshi Egami, Michio Ogawa
Pages: 873-877
Published online on: 01 October 2005

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Article

Three novel VHL germline mutations in Korean patients with von Hippel-Lindau disease and pheochromocytomas

Hio Chung Kang, Il-Jin Kim, Jae-Hyun Park, Yong Shin, Sang-Geun Jang, Sun-A Ahn, Hye-Won Park, Sun-Kyung Lim, Seung Keun Oh, Dae Jung Kim, Kwan Woo Lee, Young-Sik Choi, Young Joo Park, Min Ro Lee, Duck-Woo Kim, Jae-Gahb Park
Pages: 879-883
Published online on: 01 October 2005

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Article

Oncoprotein expression and morphological phenotypes of human breast epithelial cells transformed by the c-Ha-ras oncogene

G. M. Calaf, M. E. Alvarado, T. K. Hei
Pages: 885-893
Published online on: 01 October 2005

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Article

Detection of circulating tumor cells from renal carcinoma patients: experiences of a two-center study

Karen Blümke, Udo Bilkenroth, Uta Schmidt, Andres Melchior, Susanne Füssel, Frank Bartel, Hans Heynemann, Paolo Fornara, Helge Taubert, Manfred P. Wirth, Axel Meye
Pages: 895-899
Published online on: 01 October 2005

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Article

Analysis of p53 status in human cell lines using a functional assay in yeast: Detection of new non-sense p53 mutation in codon 124

Jana Smardová, Sárka Pavlová, Miluska Svitáková, Diana Grochová, Barbora Ravcuková
Pages: 901-907
Published online on: 01 October 2005

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Article

Expression of HIF-1α and Glut-1 in human bladder cancer

V. Palit, R. M. Phillips, R. Puri, T. Shah, M. C. Bibby
Pages: 909-913
Published online on: 01 October 2005

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Article

Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer

Hung Trinh Viet, Dick Wågsäter, Anders Hugander, Jan Dimberg
Pages: 915-918
Published online on: 01 October 2005

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Article

A polymorphism in the 5'-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population

Toshihiko Iizasa, Masayuki Baba, Yukio Saitoh, Makoto Suzuki, Yukiko Haga, Akira Iyoda, Hao Chang, Kenzo Hiroshima, Sakae Itoga, Takeshi Tomonaga, Fumio Nomura, Takehiko Fujisawa
Pages: 919-923
Published online on: 01 October 2005

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Article

Gene expression profiling of a clonal isolate of oxaliplatin-resistant ovarian carcinoma cell line A2780/C10

Rama R. Varma, Suzanne M. Hector, Kimberly Clark, William R. Greco, Lesleyann Hawthorn, Lakshmi Pendyala
Pages: 925-932
Published online on: 01 October 2005

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Article

Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: A feasible and effective salvage treatment for lymphoid malignancies

Marino Clavio, Alberto Garrone, Ivana Pierri, Gian Luca Michelis, Manuela Balocco, Alessandra Albarello, Riccardo Varaldo, Paolo Canepa, Maurizio Miglino, Filippo Ballerini, Letizia Canepa, Marco Gobb
Pages: 933-940
Published online on: 01 October 2005

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Article

Reduced radiosensitivity and increased CD40 expression in cyclophosphamide-resistant subclones established from human cervical squamous cell carcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa, Tomoko Utsunomiya, Naohiko Umesaki
Pages: 941-948
Published online on: 01 October 2005

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Article

Radiation-induced cell death is independent of the apoptotic signals mediated by death-associated protein kinase in human cervical squamous cell carcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa, Naohiko Umesaki
Pages: 949-955
Published online on: 01 October 2005

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Article

Mechanism of cell cycle arrest by (8E,13Z,20Z)-strobilinin/(7E,13Z,20Z)-felixinin from a marine sponge Psammocinia sp.

Yahong Jiang, Eun-Young Ahn, Seung-Hee Ryu, Dong-Kyoo Kim, Jang-Su Park, Shin Won Kang, Song You, Burm-Jong Lee, Jee H. Jung
Pages: 957-962
Published online on: 01 October 2005

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Article

Alterations of the p14ARF-p53-MDM2 pathway in oral squamous cell carcinoma: MDM2 overexpression is a common event

Kue Peng Lim, Hamid Sharifah, Shin Hin Lau, Soo-Hwang Teo, Sok Ching Cheong
Pages: 963-968
Published online on: 01 October 2005

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Article

Administration of dendritic cells in cancer nodules in hepatocellular carcinoma

Teru Kumagi, S. M. Fazle Akbar, Norio Horiike, Kiyotaka Kurose, Masashi Hirooka, Atsushi Hiraoka, Yoichi Hiasa, Kojiro Michitaka, Morikazu Onji
Pages: 969-973
Published online on: 01 October 2005

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Article

5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines

Tatsuo Kanda, Motohisa Tada, Fumio Imazeki, Osamu Yokosuka, Keiichi Nagao, Hiromitsu Saisho
Pages: 975-979
Published online on: 01 October 2005

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Article

Distinct response to ionizing radiation of human prostate cell lines

Venera Cardile, Marcello Bellia, Laura Lombardo, Christian Scifo, Marcella Renis
Pages: 981-985
Published online on: 01 October 2005

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Article

Impact of orotate phosphoribosyl transferase activity as a predictor of lymph node metastasis in gastric cancer

Takumi Ochiai, Michiharu Sugitani, Kazuhiko Nishimura, Hajime Noguchi, Tsuyoshi Okada, Masakazu Ouchi, Masaki Yamada, Masayuki Kitajima, Yuko Tsuruoka, Yuka Takahashi, Shunji Futagawa
Pages: 987-992
Published online on: 01 October 2005

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Article

Expression of the inhibitors of apoptosis proteins in cisplatin-resistant prostate cancer cells

Takeo Nomura, Mutsushi Yamasaki, Yoshio Nomura, Hiromitsu Mimata
Pages: 993-997
Published online on: 01 October 2005

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Article

Clinical benefits of hepatocellular carcinoma surveillance: A single-center, hospital-based study

Naota Taura, Keisuke Hamasaki, Kazuhiko Nakao, Tatsuki Ichikawa, Daisuke Nishimura, Takashi Goto, Mariko Fukuta, Hiroshi Kawashimo, Yasuhide Motoyoshi, Hidetaka Shibata, Katsumi Eguchi
Pages: 999-1003
Published online on: 01 October 2005

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Article

DNA image cytometry on sections compared with flow cytometry in human bone metastases

David Wohlrab, Thomas Klapperstück, Hans-Jürgen Holzhausen, Andreas Held, Werner Hein
Pages: 1005-1012
Published online on: 01 October 2005

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Article

Concentration of thymidine kinase 1 in serum (S-TK1) is a more sensitive proliferation marker in human solid tumors than its activity

Qimin He, Pinggn Zhang, Li Zou, Hongxun Li, Xiuqin Wang, Shan Zhou, Tommy Fornander, Sven Skog
Pages: 1013-1019
Published online on: 01 October 2005

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Article

Prognostic impact of the detection of microcirculating tumor cells by a real-time RT-PCR assay of tyrosine hydroxylase in patients with advanced neuroblastoma

Andreu Parareda, Soledad Gallego, Josep Roma, Anna Llort, Constantino Sábado, Luis Gros, Josep Sánchez De Toledo
Pages: 1021-1027
Published online on: 01 October 2005

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Article

Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients

Isabelle Solassol, Laetitia Caumette, Françoise Bressolle, Frédéric Garcia, Simon Thézenas, Cécile Astre, Stéphane Culine, Rémi Coulouma, Frédéric Pinguet
Pages: 1029-1036
Published online on: 01 October 2005

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Article

Erythropoietic agents in anaemic patients with cancer: a retrospective observational survey of epoetin α, epoetin β and darbepoetin α use in routine clinical practice

Eric Pujade-Lauraine, Alain J. Richard, Claudine Sapède, Colin Hayward
Pages: 1037-1044
Published online on: 01 October 2005

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Article

DNA vaccines based on chimeric potyvirus-like particles carrying HPV16 E7 peptide (aa 44-60)

Dana Pokorna, Noemi Cerovska, Michal Smahel, Tomas Moravec, Viera Ludvikova, Jana Mackova, Helena Synkova, Martina Duskova, Pavel Hozak, Jiri Veleminsky
Pages: 1045-1053
Published online on: 01 October 2005

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Article

CCK2 gastrin receptor as a potential target for therapy in leukaemia cell lines

M. Stubbs, K. Khan, R. G. Wickremasinghe, K. Ganeshaguru, M. E. Caplin
Pages: 1055-1058
Published online on: 01 October 2005

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Review

Potential role of calmodulin-dependent phosphodiesterase in human brain tumor (Review)

Shankar B. Das, Rajendra K. Sharma
Pages: 1059-1063
Published online on: 01 October 2005

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Article

E-cadherin immunoreactivity correlates with recurrence and progression of minimally invasive transitional cell carcinomas of the urinary bladder

Anne Mahnken, Ingo Kausch, Alfred C. Feller, Stefan Krüger
Pages: 1065-1070
Published online on: 01 October 2005

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Article

A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma

Josephine Issakov, Yehuda Kollender, Viacheslav Soyfer, Jacob Bickels, Gideon Flusser, Isaac Meller, Ofer Merimsky
Pages: 1071-1076
Published online on: 01 October 2005

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Article

Is it reasonable to consider second-line chemotherapy in patients with hormone-refractory prostate cancer?

Karel Odrazka, Miloslava Vaculikova, Martin Dolezel, Jiri Petera, Petr Moravek, Petr Prosvic, Zdenek Zoul, Milan Vosmik, Jiri Dolezal, Eva Simakova
Pages: 1077-1081
Published online on: 01 October 2005

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Article

Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs

Masuko Katoh, Masaru Katoh
Pages: 1083-1086
Published online on: 01 October 2005

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Article

Comparative genomics on Sonic Hedgehog orthologs

Yuriko Katoh, Masaru Katoh
Pages: 1087-1090
Published online on: 01 October 2005

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Article

Relative imbalances in the expression of estrogen-metabolizing enzymes in the breast tissue of women with breast carcinoma

Seema Singh, Dhrubajyoti Chakravarti, James A. Edney, Ronald R. Hollins, Perry J. Johnson, William W. West, Sheila M. Higginbotham, Ercole L. Cavalieri, Eleanor G. Rogan
Pages: 1091-1096
Published online on: 01 October 2005

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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