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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2006 Volume 16 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0

M. Waheed Roomi, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 943-947
Published online on: 01 November 2006

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Article

The genetic differences between gallbladder and bile duct cancer cell lines

Soichiro Saito, Mila Ghosh, Keiko Morita, Takashi Hirano, Masanao Miwa, Takeshi Todoroki
Pages: 949-956
Published online on: 01 November 2006

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Article

Aberrant promoter hypermethylation profile of cell cycle regulatory genes in malignant astrocytomas

Takashi Ohta, Takao Watanabe, Yoichi Katayama, Atsuo Yoshino, Kazunari Yachi, Akiyoshi Ogino, Chiaki Komine, Takao Fukushima
Pages: 957-963
Published online on: 01 November 2006

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Article

Sequential endoscopic findings and histological changes of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats

Tetsuya Baden, Keigo Yamamichi, Taku Michiura, Airo Tsubura, Koshiro Hioki
Pages: 965-970
Published online on: 01 November 2006

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Case Report

Irinotecan cytotoxicity does not necessarily depend on the UGT1A1 polymorphism but on fluoropyrimidine: A molecular case report

Yasuhiro Inoue, Chikao Miki, Hideki Watanabe, Junichiro Hiro, Yuji Toiyama, Eiki Ojima, Kaname Nakatani, Tsutomu Nobori, Masato Kusunoki
Pages: 971-974
Published online on: 01 November 2006

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Article

Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells

Sung Jin Kim, Han Saem Lee, June Ho Shin, Chul Geun Kim, Sunjoo Jeong, Keerang Park, Han Choe, Heuiran Lee
Pages: 975-979
Published online on: 01 November 2006

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Article

Great potential of a panel of multiple hMTH1, SPD, ITGA11 and COL11A1 markers for diagnosis of patients with non-small cell lung cancer

Inn-Wen Chong, Mei-Yin Chang, Huang-Chou Chang, Ya-Ping Yu, Chau-Chyun Sheu, Jong-Rung Tsai, Jen-Yu Hung, Shah-Hwa Chou, Mee-Sun Tsai, Jhi-Jhu Hwang, Shiu-Ru Lin
Pages: 981-988
Published online on: 01 November 2006

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Article

Catalpa seed oil rich in 9t,11t,13c-conjugated linolenic acid suppresses the development of colonic aberrant crypt foci induced by azoxymethane in rats

Rikako Suzuki, Yumiko Yasui, Hiroyuki Kohno, Shingo Miyamoto, Masashi Hosokawa, Kazuo Miyashita, Takuji Tanaka
Pages: 989-996
Published online on: 01 November 2006

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Article

Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells

Masanori Hirama, Seiji Isonishi, Makoto Yasuda, Hiroshi Ishikawa
Pages: 997-1002
Published online on: 01 November 2006

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Article

Overexpression of PAX5 in oral carcinogenesis

Sufi Norhany, Yukinao Kouzu, Katsuhiro Uzawa, Masayo Hayama, Morihiro Higo, Hirofumi Koike, Atsushi Kasamatu, Hideki Tanzawa
Pages: 1003-1008
Published online on: 01 November 2006

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Article

Gene expression pattern in oral cancer cervical lymph node metastasis

Yoshikuni Kato, Katsuhiro Uzawa, Kengo Saito, Dai Nakashima, Masaki Kato, Yoshinori Nimura, Naohiko Seki, Hideki Tanzawa
Pages: 1009-1014
Published online on: 01 November 2006

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Article

PAX8 expression in human bladder cancer

Lucia Pellizzari, Cinzia Puppin, Laura Mariuzzi, Francesca Saro, Maura Pandolfi, Roberto Di Lauro, Carlo Alberto Beltrami, Giuseppe Damante
Pages: 1015-1020
Published online on: 01 November 2006

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Article

Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells

Runqiu Jiang, Wenrong Xu, Wei Zhu, Miao Chen, Hui Qian, Chun Qiao, Huan Yang, Xingzhong Wang, Yongchang Chen
Pages: 1021-1028
Published online on: 01 November 2006

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Article

Significance of cyclin E and p27 expression in malignant ovarian germ cell tumors: Correlation with the cell proliferation activity and clinicopathologic features

Shigeto Kawauchi, Yoshiaki Yamamoto, Ken-ichiro Uchida, Yasuyo Chochi, Tomoko Kondo, Atsunori Oga, Kohsuke Sasaki
Pages: 1029-1033
Published online on: 01 November 2006

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Article

Interactive effect of genetic polymorphism of glutathione S-transferase M1 and smoking on squamous cell lung cancer risk in Korea

Kyoung-Mu Lee, Daehee Kang, Seung-Joon Lee, Sue Kyung Park, Kwan-Hee Lee, Ji-Yeob Choi, Soo-Ung Kim, Hwang Choi, Seung-Ho Choi, Young-Whan Kim, Yun-Chul Hong, Soo-Hun Cho
Pages: 1035-1039
Published online on: 01 November 2006

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Article

Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations

Andrzej Semczuk, Anna Lorenc, Lechoslaw Putowski, Konrad Futyma, Jaroslaw Bryk, Pawel Miotla, Ewa Bartnik
Pages: 1041-1045
Published online on: 01 November 2006

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Article

Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells

K. Saravana Kumar, Jürgen Sonnemann, James F. Beck
Pages: 1047-1052
Published online on: 01 November 2006

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Article

Array-based comparative genomic hybridization of circulating esophageal tumor cells

Dal Ho Kim, Manabu Muto, Yoshitaka Kuwahara, Yukihiro Nakanishi, Hiroshi Watanabe, Kazuhiko Aoyagi, Kenji Ogawa, Teruhiko Yoshida, Hiroki Sasaki
Pages: 1053-1059
Published online on: 01 November 2006

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Article

Intraoperative pathological investigation of recurrent nerve nodal metastasis can guide the decision whether to perform cervical lymph node dissection in thoracic esophageal cancer

Yuji Ueda, Atsushi Shiozaki, Hirosumi Itoi, Kazuma Okamoto, Hitoshi Fujiwara, Daisuke Ichikawa, Shojiro Kikuchi, Nobuaki Fuji, Tsuyoshi Itoh, Toshiya Ochiai, Shuhei Komatsu, Hisakazu Yamagishi
Pages: 1061-1066
Published online on: 01 November 2006

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Article

Successful treatment of large-size advanced hepatocellular carcinoma by transarterial chemoembolization followed by the combination therapy of percutaneous ethanol-lipiodol injection and radiofrequency ablation

Kazutaka Kurokohchi, Naoki Hosomi, Akira Yoshitake, Tomohiro Ohgi, Masahiro Ono, Tsuyoshi Maeta, Takaaki Kiuchi, Ichiro Matsumoto, Tsutomu Masaki, Hirohito Yoneyama, Fumikazu Kohi, Shigeki Kuriyama
Pages: 1067-1070
Published online on: 01 November 2006

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Article

Increased expression of CENP-H gene in human oral squamous cell carcinomas harboring high-proliferative activity

Hideo Shigeishi, Koichiro Higashikawa, Shigehiro Ono, Kuniko Mizuta, Yoshiaki Ninomiya, Shingo Yoneda, Masayuki Taki, Nobuyuki Kamata
Pages: 1071-1075
Published online on: 01 November 2006

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Article

Cobrotoxin-containing analgesic compound to treat chronic moderate to severe cancer pain: Results from a randomized, double-blind, cross-over study and from an open-label study

J. M. Xu, S. T. Song, F. Y. Feng, F. L. Huang, Y. Yang, G. R. Xie, L. G. Xu, C. Z. Zhang, M. Bruno, A. Paradiso
Pages: 1077-1084
Published online on: 01 November 2006

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Article

The optimal schedule for 5-fluorouracil radiosensitization in colon cancer cell lines

Eiki Ojima, Yasuhiro Inoue, Hideki Watanabe, Junichiro Hiro, Yuji Toiyama, Chikao Miki, Masato Kusunoki
Pages: 1085-1091
Published online on: 01 November 2006

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Article

Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients

Masakazu Sano, Nobuyuki Genkai, Naoki Yajima, Naoto Tsuchiya, Junpei Homma, Ryuichi Tanaka, Toru Miki, Ryuya Yamanaka
Pages: 1093-1098
Published online on: 01 November 2006

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Article

p27KIP1 and GATA-1 are potential downstream molecules in activin A-induced differentiation and apoptosis pathways in CML cells

Yumi Fukuchi, Kenji Yamato, Chiharu Kawamura, Yasuo Ikeda, Masahiro Kizaki
Pages: 1099-1103
Published online on: 01 November 2006

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Article

Humoral immune response to p16, a cyclin-dependent kinase inhibitor in human malignancies

Koksun Looi, Roxanne Megliorino, Fu-Dong Shi, Xuan-Xian Peng, Yao Chen, Jian-Ying Zhang
Pages: 1105-1110
Published online on: 01 November 2006

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Article

Genotype of thymidylate synthase likely to affect efficacy of adjuvant 5-FU based chemotherapy in colon cancer

Takanori Matsui, Kenji Omura, Kazuyuki Kawakami, Satoshi Morita, Junichi Sakamoto
Pages: 1111-1115
Published online on: 01 November 2006

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Article

A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma

Doo-Sik Kong, Jung-Il Lee, Won Seog Kim, Myung Jin Son, Do Hoon Lim, Sung Tae Kim, Kwan Park, Jong Hyun Kim, Whan Eoh, Do-Hyun Nam
Pages: 1117-1121
Published online on: 01 November 2006

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Article

Variability in the diagnosis of dysplasia in ulcerative colitis by dynamic telepathology

Robert D. Odze, John E. Tomaszewski, Emma E. Furth, Michael D. Feldman, Raihanatou Diallo, Christopher Poremba, Ingrid Becker, Heinz Hoefler, John R. Goldblum, Lisa A. Rybicki, Nada Alsaigh, Franz Fogt
Pages: 1123-1129
Published online on: 01 November 2006

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Article

p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis

Soo-Jeong Lim, Young-Ju Lee, Eunmyong Lee
Pages: 1131-1135
Published online on: 01 November 2006

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Article

Different molecular pathways determining extrahepatic and intrahepatic recurrences of hepatocellular carcinoma

Norio Iizuka, Takao Tamesa, Kazuhiko Sakamoto, Takanobu Miyamoto, Yoshihiko Hamamoto, Masaaki Oka
Pages: 1137-1142
Published online on: 01 November 2006

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Article

Rapid immunohistochemical detection of tumor cells in gastric carcinoma

Stefan P. Mönig, Thomas Luebke, Afsoon Soheili, Stephanie Landsberg, H. P. Dienes, Arnulf H. Hölscher, Stephan E. Baldus
Pages: 1143-1147
Published online on: 01 November 2006

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Article

Connexin 32 expression reduces malignant phenotype in human A549 adenocarcinoma cells: Implication of Src involvement

Sachio Hada, Hiromi Sato, Nantiga Virgona, Hiromi Hagiwara, Terunobu Saito, Kazuyuki Suzuki, Ryuji Asano, Tomohiro Yano
Pages: 1149-1154
Published online on: 01 November 2006

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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