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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2007 Volume 18 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Differential spatial expression and activation pattern of EGFR and HER2 in human breast cancer

Anneliese Fink-Retter, Daphne Gschwantler-Kaulich, Gernot Hudelist, Ruth Mueller, Ernst Kubista, Klaus Czerwenka, Christian F. Singer
Pages: 299-304
Published online on: 01 August 2007

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Article

Expression and prognostic relevance of endothelin-B receptor in vulvar cancer

Elke Eltze, Matteo Bertolin, Eberhard Korsching, Pia Wülfing, Tiziano Maggino, Ralph Lellé
Pages: 305-311
Published online on: 01 August 2007

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Article

Contrasting effects of extended low dose versus standard dose shorter course UFT chemotherapy on microscopic versus macroscopic established tumors: Implications for optimal postoperative adjuvant chemotherapy

Junji Uchida, Hiroyuki Okabe, Koushi Nakano, Akio Fujioka, Hitoshi Saito, Yoshikazu Sugimoto, Toshinori Oka, Masakazu Fukushima
Pages: 313-319
Published online on: 01 August 2007

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Article

Gene expression profiling of metastatic brain cancer

Vahe Michael Zohrabian, Hari Nandu, Nicholas Gulati, Greg Khitrov, Connie Zhao, Avinash Mohan, Joseph DeMattia, Alex Braun, Kaushik Das, Raj Murali, Meena Jhanwar-Uniyal
Pages: 321-328
Published online on: 01 August 2007

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Article

Melanoma-associated antigen-A1 expression predicts resistance to docetaxel and paclitaxel in advanced and recurrent gastric cancer

Takahisa Suzuki, Kazuhiro Yoshida, Yoshiyuki Wada, Yoichi Hamai, Kazuhiro Sentani, Naohide Oue, Wataru Yasui
Pages: 329-336
Published online on: 01 August 2007

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Article

N-methyl-N-nitrosourea-induced mammary carcinogenesis is promoted by short-term treatment with estrogen and progesterone mimicking pregnancy in aged female Lewis rats

Reiko Tsukamoto, Takako Mikami, Katsuaki Miki, Norihisa Uehara, Takashi Yuri, Yoichiro Matsuoka, Kazuichi Okazaki, Airo Tsubura
Pages: 337-342
Published online on: 01 August 2007

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Article

Differential levels of human leukocyte antigen-class I, multidrug-resistance 1 and androgen receptor expressions in untreated prostate cancer cells: The robustness of prostate cancer

Shigenori Homma, Yoshihiro Komohara, Mamoru Harada, Hideyuki Saya, Satoru Todo, Kyogo Itoh, Masanori Noguchi
Pages: 343-346
Published online on: 01 August 2007

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Article

Induction of apoptosis by rhapontin having stilbene moiety, a component of rhubarb (Rheum officinale Baillon) in human stomach cancer KATO III cells

Hiroshige Hibasami, Keiji Takagi, Toshiaki Ishii, Mayumi Tsujikawa, Nami Imai, Ikumi Honda
Pages: 347-351
Published online on: 01 August 2007

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Article

Enhanced susceptibility of adriamycin-treated human renal cell carcinoma cells to lysis by peripheral blood lymphocytes and tumor infiltrating lymphocytes

X. X. Wu, Y. Zeng, X. H. Jin, Y. Kakehi
Pages: 353-359
Published online on: 01 August 2007

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Article

Expression of glucose transporters in epithelial ovarian carcinoma: Correlation with clinical characteristics and tumor angiogenesis

Miho Tsukioka, Yoshinari Matsumoto, Maiko Noriyuki, Chika Yoshida, Hiroyuki Nobeyama, Hiroyuki Yoshida, Tomoyo Yasui, Toshiyuki Sumi, Ken-ichi Honda, Osamu Ishiko
Pages: 361-367
Published online on: 01 August 2007

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Article

Does preoperative chemo-radiotherapy enhance the expression of vascular endothelial growth factor in patients with rectal cancer?

Yasuhiro Inoue, Eiki Ojima, Hideki Watanabe, Junichiro Hiro, Yuji Toiyama, Minako Kobayashi, Chikao Miki, Masato Kusunoki
Pages: 369-375
Published online on: 01 August 2007

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Article

Up-regulated claudin 7 expression in intestinal-type gastric carcinoma

Jeong Youp Park, Kyung Hwa Park, Tae Yun Oh, Sung Pil Hong, Tae Joo Jeon, Chang Hoon Kim, Seung Woo Park, Jae Bock Chung, Si Young Song, Seungmin Bang
Pages: 377-382
Published online on: 01 August 2007

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Article

Downregulation of survivin expression and elevation of caspase-3 activity involved in pitavastatin-induced HepG 2 cell apoptosis

Juyong Wang, Zhenye Xu, Ming Zhang
Pages: 383-387
Published online on: 01 August 2007

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Article

Prognostic significance of p21WAF1/CIP1, p16INK4a and CD44s in tongue cancer

M. A. González-Moles, J. A. Gil-Montoya, I. Ruiz-Avila, F. Esteban, M. Delgado-Rodriguez, A. Bascones-Martinez
Pages: 389-396
Published online on: 01 August 2007

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Article

Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA

Y. Shi, Y. Tian, Y. Q. Zhou, J. Y. Ju, L. Qu, S. L. Chen, Z. G. Xiang, Y. Liu, L. P. Zhu
Pages: 397-403
Published online on: 01 August 2007

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Article

Deletion analysis of tumor and urinary DNA to detect bladder cancer: Urine supernatant versus urine sediment

Tibor Szarvas, Ilona Kovalszky, Katalin Bedi, Attila Szendroi, Attila Majoros, Péter Riesz, Tibor Füle, Viktória László, András Kiss, Imre Romics
Pages: 405-409
Published online on: 01 August 2007

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Article

p73γ transactivates the p21 promoter through preferential interaction with the p300/CBP-associated factor in human prostate cancer cells

Yasutomo Momii, Hiroto Izumi, Masaki Shiota, Takamitsu Onitsuka, Tatsuya Abe, Hidenori Kobayashi, Naoya Miyamoto, Takeshi Uchiumi, Kimitoshi Kohno
Pages: 411-416
Published online on: 01 August 2007

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Article

Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation

Marta Campo Dell'Orto, Barbara Banelli, Emanuela Giarin, Benedetta Accordi, Luca Trentin, Massimo Romani, Geertruy Te Kronnie, Giuseppe Basso
Pages: 417-423
Published online on: 01 August 2007

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Article

Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions

Angelina Di Carlo, Angela Mariano, Daniela Terracciano, Claudia Mazzarella, Sonia Galzerano, Marcellino Cicalese, Ciriaco Cecere, Vincenzo Macchia
Pages: 425-431
Published online on: 01 August 2007

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Article

Antitumor activity of a combination of trastuzumab (Herceptin) and oral fluoropyrimidine S-1 on human epidermal growth factor receptor 2-overexpressing pancreatic cancer

Hiroyuki Saeki, Shunsuke Yanoma, Shouji Takemiya, Yukio Sugimasa, Makoto Akaike, Norio Yukawa, Yasushi Rino, Toshio Imada
Pages: 433-439
Published online on: 01 August 2007

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Article

Growth suppression of thyroid cancer cells by adenylcyclase activator

Yukiko Yano, Hiroshi Kamma, Hirofumi Matsumoto, Masachika Fujiwara, Hiroko Bando, Hisato Hara, Tohru Yashiro, Ei Ueno, Koichi Ito, Kazuhiko Uchida
Pages: 441-445
Published online on: 01 August 2007

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Article

Hsp72 controls bortezomib-induced HepG2 cell death via interaction with pro-apoptotic factors Retraction in /10.3892/or.2026.9133

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Pages: 447-450
Published online on: 01 August 2007

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Article

Expression of a functional CCR7 chemokine receptor inhibits the post-intravasation steps of metastasis in malignant murine mammary cancer cells

Stefania Croci, Giordano Nicoletti, Lorena Landuzzi, Arianna Palladini, Francesca Chiarini, Patrizia Nanni, Pier-Luigi Lollini, Carla De Giovanni
Pages: 451-456
Published online on: 01 August 2007

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Article

Characterization of an intramolecular protein-protein interaction in c-Ets1 and its viral homologue v-Ets

Melanie Schmidt, André Michael Schmidt, Johannes Dietl, Ulrike Kammerer
Pages: 457-463
Published online on: 01 August 2007

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Article

Integrated analysis of expression and genome alteration reveals putative amplified target genes in esophageal cancer

Takashi Sugimoto, Makoto Arai, Hideaki Shimada, Akira Hata, Naohiko Seki
Pages: 465-472
Published online on: 01 August 2007

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Article

Interleukin-1β gene in esophageal, gastric and colorectal carcinomas

H. Ito, K. Kaneko, R. Makino, K. Konishi, T. Kurahashi, T. Yamamoto, A. Katagiri, Y. Kumekawa, Y. Kubota, T. Muramoto, K. Mitamura, M. Imawari
Pages: 473-481
Published online on: 01 August 2007

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Article

Galectin-1 expression in human glioma cells: Modulation by ionizing radiation and effects on tumor cell proliferation and migration

Herwig M. Strik, Katharina Schmidt, Paul Lingor, Lars Tönges, Wilfried Kugler, Mirko Nitsche, Gabriel A. Rabinovich, Mathias Bähr
Pages: 483-488
Published online on: 01 August 2007

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Article

Low expression of ORF4, a dominant negative variant of peroxisome proliferator-activated receptor γ, in colorectal adenocarcinoma

Delphine Bouancheau, Anne Jarry, Stephanie Mottier, Claire Toquet, Damien Masson, Jean-François Mosnier, Christian L. Laboisse, Marc G. Denis
Pages: 489-495
Published online on: 01 August 2007

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Article

Specific components of prostanoid-signaling pathways are present in non-small cell lung cancer cells

Mihaela Kreutzer, Tanja Fauti, Kerstin Kaddatz, Carola Seifart, Andreas Neubauer, Horst Schweer, Martin Kömhoff, Sabine Müller-Brüsselbach, Rolf Müller
Pages: 497-501
Published online on: 01 August 2007

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Article

Uncoupling of the epidermal growth factor receptor from downstream signal transduction molecules guides the acquired resistance to gefitinib in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Danilo Millimaggi, Paola Muzi, Silvia Speca, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Pages: 503-511
Published online on: 01 August 2007

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Article

Effect of a novel fully human monovalent antigen-binding fragment on the survival of cancer cell lines

Yong Soon Kwon, You-Ri Lee, Yong-Sung Kim, Hyun-Wook Lee, Young-Ju Jang
Pages: 513-517
Published online on: 01 August 2007

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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