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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2008 Volume 20 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients

Milka Georgieva, Maria Krasteva, Elka Angelova, Krassimir Ralchev, Valentin Dimitrov, Stanislav Bozhimirov, Elena Georgieva, Martin R. Berger
Pages: 3-11
Published online on: 01 July 2008

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Article

Experimental characterization of recurrent ovarian immature teratoma cells after optimal surgery

Tetsuji Tanaka, Saori Toujima, Tomoko Utsunomiya, Kazunori Yukawa, Naohiko Umesaki
Pages: 13-23
Published online on: 01 July 2008

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Article

Clinical significance of intra-tumoral sinusoidal structures showing lympho-endothelial immunoreactivity in breast cancer

Kenji Tezuka, Naoyoshi Onoda, Tsutomu Takashima, Tetsuro Ishikawa, Tomoko Wakasa, Kenichi Wakasa, Kosei Hirakawa
Pages: 25-32
Published online on: 01 July 2008

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Article

Laminin-5 (γ2 chain) is a marker of invading cancer cells in human gallbladder carcinoma: Special emphasis on extension of carcinoma in situ along Rokitansky-Aschoff sinuses

Takashi Eguchi, Takahiro Inoue, Kei Fujii, Hiroshi Yamaguchi, Ken-Ichi Nishiyama, Hirotoshi Yonemasu, Takashi Yao, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 33-39
Published online on: 01 July 2008

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Article

Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-κB in HCT116 colon cancer cells

Hye Ran Lee, Hee-Jeong Cheong, Sook-Ja Kim, Nam-Su Lee, Hee-Sook Park, Jong-Ho Won
Pages: 41-47
Published online on: 01 July 2008

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Article

Clinical implications of the MDM2 SNP309 and p53 Arg72Pro polymorphisms in transitional cell carcinoma of the bladder

Yohei Horikawa, Junichi Nadaoka, Mitsuru Saito, Teruaki Kumazawa, Takamitu Inoue, Takeshi Yuasa, Norihiko Tsuchiya, Hiroyuki Nishiyama, Osamu Ogawa, Tomonori Habuchi
Pages: 49-55
Published online on: 01 July 2008

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Article

Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP

Ken Ohnishi, Yoko Nagata, Akihisa Takahashi, Shigeki Taniguchi, Takeo Ohnishi
Pages: 57-61
Published online on: 01 July 2008

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Article

Survivin and cyclin D1 are jointly expressed in thyroid papillary carcinoma and microcarcinoma

Alfredo Antonaci, Fabrizio Consorti, Stefania Mardente, Stefania Natalizi, Gloria Giovannone, Carlo Della Rocca
Pages: 63-67
Published online on: 01 July 2008

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Article

Cancer patients treated with the Banerji protocols utilising homoeopathic medicine: A Best Case Series Program of the National Cancer Institute USA

Prasanta Banerji, Donald R. Campbell, Pratip Banerji
Pages: 69-74
Published online on: 01 July 2008

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Article

Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study

Karel Smetana, Barbora Dvoránková, Lukás Lacina, Zdenek Cada, Vladimír Vonka
Pages: 75-80
Published online on: 01 July 2008

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Article

Mouse macrophage metalloelastase generates angiostatin from plasminogen and suppresses tumor angiogenesis in murine colon cancer

Zhangwei Xu, Hai Shi, Qi Li, Qiao Mei, Junjun Bao, Yuxian Shen, Jianming Xu
Pages: 81-88
Published online on: 01 July 2008

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Article

Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry

Cesar Sze-Chuen Wong, Vicky Wai-Ki Wong, Charles Ming-Lok Chan, Brigette Buig-Yue Ma, Edwin Pun Hui, Manson Chi-Keung Wong, Money Yan-Yee Lam, Thomas Chi-Chuen Au, Wing-Han Chan, Wah Cheuk, Anthony Tak-Cheung Chan
Pages: 89-98
Published online on: 01 July 2008

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Article

Novel complex t(V;9;22) rearrangements in three cases with chronic myeloid leukemia and a rare translocation in a case with classical Philadelphia chromosome

Hasmik Mkrtchyan, Seda Ghazaryan, Gayane Avetisyan, Anna Hovhannisyan, Laura Muradyan, Smbat Daghbashyan, Constanze Karst, Madeleine Gross, Sophie Hinreiner, Rouben Aroutiounian, Thomas Liehr
Pages: 99-104
Published online on: 01 July 2008

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Article

Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma

Dragomira Nikolaeva Nikolova, Hitoshi Zembutsu, Tanio Sechanov, Kalin Vidinov, Low Siew Kee, Radina Ivanova, Elitza Becheva, Miriana Kocova, Draga Toncheva, Yusuke Nakamura
Pages: 105-121
Published online on: 01 July 2008

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Article

Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis

Petra Goldin-Lang, Quoc-Viet Tran, Iduna Fichtner, Andreas Eisenreich, Silvio Antoniak, Karsten Schulze, Sarah E. Coupland, Wolfgang Poller, Heinz-Peter Schultheiss, Ursula Rauch
Pages: 123-128
Published online on: 01 July 2008

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Article

Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis

Ju-Hee Lee, Don-Haeng Lee, Hyun-Seung Lee, Joon-Seok Choi, Kyu-Won Kim, Soon-Sun Hong
Pages: 129-134
Published online on: 01 July 2008

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Article

Lentivirus-mediated short hairpin RNA targeting the APRIL gene suppresses the growth of pancreatic cancer cells in vitro and in vivo

Feng Wang, Lin Chen, Zhen-Biao Mao, Jian-Guo Shao, Chang Tan, Wei-Da Huang
Pages: 135-139
Published online on: 01 July 2008

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Article Open Access

Geographic variations of human papilloma virus infection and their possible impact on the effectiveness of the vaccination programme

Ioannis N. Mammas, Dimitra Vageli, Demetrios A. Spandidos
Pages: 141-145
Published online on: 01 July 2008

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Article

Decomposition of dextran sulfate sodium under alkaline, acidic, high temperature and high pressure conditions

Yoshio Araki, Ken-Ichi Mukaisyo, Hiroyuki Sugihara, Takanori Hattori
Pages: 147-149
Published online on: 01 July 2008

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Article

Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells

Zhaoxu Liu, Marcela Marquez, Sten Nilsson, Anders R. Holmberg
Pages: 151-154
Published online on: 01 July 2008

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Article

Adoptive immunotherapy for pancreatic cancer: Cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1

Toru Kawaoka, Masaaki Oka, Motonari Takashima, Tomio Ueno, Koutaro Yamamoto, Noboru Yahara, Shigefumi Yoshino, Shoichi Hazama
Pages: 155-163
Published online on: 01 July 2008

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Article

Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction

Satoshi Tanaka, Jiro Akimoto, Ikuo Kobayashi, Hidehiro Oka, Hiroshi Ujiie
Pages: 165-171
Published online on: 01 July 2008

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Article

Evaluation of lung lesions using FDG γ-camera PET equipped with a one-inch crystal

Hong-Wei Zhan, Hai-Feng Cheng, Xiao-Juan Ye, Chun-Lei Zhao, Hong Zhang, Hong-Biao Liu, Gang-Qiang He
Pages: 173-178
Published online on: 01 July 2008

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Article

The Gln/Gln genotype of XPD codon 751 as a genetic marker for melanoma risk and Lys/Gln as an important predictor for melanoma progression: A case control study in the Swedish population

Khadija Kertat, Inger Rosdahl, Xiao-Feng Sun, Ingrid Synnerstad, Hong Zhang
Pages: 179-183
Published online on: 01 July 2008

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Article

Prognostic factors in follicular lymphoma: A single institution study

N. Jacobi, T. B. Rogers, B. A. Peterson
Pages: 185-193
Published online on: 01 July 2008

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Article

Differential expression of Wnt13 isoforms during leukemic cell differentiation

Rodica Petruta Bunaciu, Tao Tang, Catherine D. Mao
Pages: 195-201
Published online on: 01 July 2008

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Article

Somatic alterations in brain tumors

Jill Barnholtz-Sloan, Andrew E. Sloan, Susan Land, William Kupsky, Alvaro N.A. Monteiro
Pages: 203-210
Published online on: 01 July 2008

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Article

Production and verification of human papillomavirus type 18 vaccine in vitro

Shujie Liao, Shixuan Wang, Ling Xu, Dongrui Deng, Qian Xu, Wei Wang, Tao Zhu, Xiangyang Bai, Jianfeng Zhou, Gang Xu, Yunping Lu, Li Meng, Ding Ma
Pages: 211-217
Published online on: 01 July 2008

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Article

Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells

Jürgen Sonnemann, Isabel Hüls, Michael Sigler, Chithra D. Palani, Le Thi Thu Hong, Uwe Völker, Heyo K. Kroemer, James F. Beck
Pages: 219-224
Published online on: 01 July 2008

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Article

Antitumoral activity of new polyamine-naphthoquinone conjugates

Andressa Esteves-Souza, Kelly Araújo Lucio, Andréa Sousa Da Cunha, Angelo Da Cunha Pinto, Edson Luiz Da Silva Lima, Celso Amorim Camara, Maria Domingues Vargas, Cerli Rocha Gattass
Pages: 225-231
Published online on: 01 July 2008

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Article

A phase II clinical trial of gemcitabine and split dose cisplatin in advanced non-small cell lung cancer in an outpatient setting

S. A. Hussain, D. H. Palmer, D. E. Swinson, P. Riley, A. Wills, C. Brown, C. Draycott, A. El-Modir, D. R. Peake, D. W. Rea, A. D. Chetiyawardana, M. H. Cullen
Pages: 233-237
Published online on: 01 July 2008

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Article

In vitro cytotoxic activity of anthrapyrazole analogues in human prostate DU-145 and testicular NTERA-2 carcinoma cells

Maria E. Cuevas, Kurt Seilheimer
Pages: 239-244
Published online on: 01 July 2008

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Article

The anti-tumor immune response induced by a combination of MAGE-3/MAGE-n-derived peptides

Xiu-Min Zhang, Yun-Fei Zhang, Yang Huang, Ping Qu, Bin Ma, Shao-Yan Si, Zeng-Shan Li, Wen-Xin Li, Xia Li, Wei Ge, Pei-Zhen Hu, Yan-Fang Sui
Pages: 245-252
Published online on: 01 July 2008

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

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Article Number: 188
Published online on: 15 September 2026

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FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
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Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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