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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2010 Volume 23 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis (Review)

Anna Chiarini, James F. Whitfield, Raffaella Pacchiana, Maddalena Marconi, Ubaldo Armato, Ilaria Dal Prà
Pages: 887-892
Published online on: 01 April 2010

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Article

RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer

Shaolei Zang, Feng Chen, Jianjian Dai, Dongmei Guo, William Tse, Xun Qu, Daoxin Ma, Chunyan Ji
Pages: 893-899
Published online on: 01 April 2010

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Article

Promotion of melanoma growth by the metabolic hormone leptin

Julie A. Ellerhorst, A. H. Diwan, Shyam M. Dang, Deon G. Uffort, Marilyn K. Johnson, Carolyn P. Cooke, Elizabeth A. Grimm
Pages: 901-907
Published online on: 01 April 2010

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Article

Expression of the HER-1-4 family of receptor tyrosine kinases in neuroendocrine tumours

Rajaventhan Srirajaskanthan, Tahir Shah, Jennifer Watkins, Laura Marelli, Korsa Khan, Martyn E. Caplin
Pages: 909-915
Published online on: 01 April 2010

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Article

Clinical significance of syndecan-1 and versican expression in human epithelial ovarian cancer

Tomoyuki Kusumoto, Junichi Kodama, Noriko Seki, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu
Pages: 917-925
Published online on: 01 April 2010

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Article

Claudin expression profiles in Epstein-Barr virus-associated nasopharyngeal carcinoma

Fumiyoshi Kojima, Mitsuaki Ishida, Mikiko Takikita-Suzuki, Machiko Hotta, Kanade Katsura, Akihiro Nagata, Yasuyuki Enoki, Gen-Ichi Kato, Hidetoshi Okabe
Pages: 927-931
Published online on: 01 April 2010

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Article

HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis

Nobuyuki Bandoh, Takeshi Ogino, Akihiro Katayama, Miki Takahara, Akihiro Katada, Tatsuya Hayashi, Yasuaki Harabuchi
Pages: 933-939
Published online on: 01 April 2010

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Article

The angiotensin-converting enzyme 2 in tumor growth and tumor-associated angiogenesis in non-small cell lung cancer

Yun Feng, Huanying Wan, Jialin Liu, Ruifeng Zhang, Qinyun Ma, Bing Han, Yi Xiang, Jiaming Che, Huangming Cao, Xiaochun Fei, Weicheng Qiu
Pages: 941-948
Published online on: 01 April 2010

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Article

Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer

Soichiro Tsunemi, Toyofumi Nakanishi, Yoshihisa Fujita, George Bouras, Yoshiharu Miyamoto, Akiko Miyamoto, Eiji Nomura, Takayuki Takubo, Nobuhiko Tanigawa
Pages: 949-956
Published online on: 01 April 2010

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Article

Antitumor effects of lapatinib (GW572016), a dual inhibitor of EGFR and HER-2, in combination with cisplatin or paclitaxel on head and neck squamous cell carcinoma

Norio Kondo, Mamoru Tsukuda, Yukari Ishiguro, Machiko Kimura, Kyoko Fujita, Atsuko Sakakibara, Hideaki Takahashi, Gabor Toth, Hideki Matsuda
Pages: 957-963
Published online on: 01 April 2010

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Article

Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma

Pavel V. Korita, Toshifumi Wakai, Yoshio Shirai, Yasunobu Matsuda, Jun Sakata, Masaaki Takamura, Masahiko Yano, Ayumi Sanpei, Yutaka Aoyagi, Katsuyoshi Hatakeyama, Yoichi Ajioka
Pages: 965-972
Published online on: 01 April 2010

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Article

The expression of NAD(P)H:quinone oxidoreductase 1 is increased along with NF-κB p105/p50 in human cutaneous melanomas

Yabin Cheng, Jun Li, Magdalena Martinka, Gang Li
Pages: 973-979
Published online on: 01 April 2010

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Article

Intratumoral injection of pEGFC1-IGFBP7 inhibits malignant melanoma growth in C57BL/6J mice by inducing apoptosis and down-regulating VEGF expression

Rong-Yi Chen, Hong-Xiang Chen, Ping Jian, Li Xu, Juan Li, Yi-Ming Fan, Ya-Ting Tu
Pages: 981-988
Published online on: 01 April 2010

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Article

Prognostic significance of insulin growth factor-I receptor and insulin growth factor binding protein-3 expression in primary breast cancer

Jun H. Kim, Young H. Cho, Yong L. Park, Jin H. Sohn, Hee S. Kim
Pages: 989-995
Published online on: 01 April 2010

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Article

MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2

Gong Chen, Wei Zhu, Dezhi Shi, Li Lv, Chun Zhang, Ping Liu, Weixing Hu
Pages: 997-1003
Published online on: 01 April 2010

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Article

The effect on radioresistance of manganese superoxide dismutase in nasopharyngeal carcinoma

Yaming Qu, Hua Zhang, Suping Zhao, Jidong Hong, Cane Tang
Pages: 1005-1011
Published online on: 01 April 2010

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Article

RNA interference-mediated hTERT inhibition enhances TRAIL-induced apoptosis in resistant hepatocellular carcinoma cells

Ru-Gang Zhang, Jing-Jing Zhao, Liu-Qin Yang, Shi-Ming Yang, Rong-Quan Wang, Wen-Sheng Chen, Gui-Yong Peng, Dian-Chun Fang
Pages: 1013-1019
Published online on: 01 April 2010

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Article

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

Gregory T. Langland, Steven M. Yannone, Rachel A. Langland, Aki Nakao, Yinghui Guan, Sydney B.T. Long, Lien Vonguyen, David J. Chen, Joe W. Gray, Fanqing Chen
Pages: 1021-1026
Published online on: 01 April 2010

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Article

BUBR1 expression in benign oral lesions and squamous cell carcinomas: Correlation with human papillomavirus

Régia C.P. Lira, Fabiana A. Miranda, Márcia C.M. Guimarães, Renata T. Simões, Eduardo A. Donadi, Christiane P. Soares, Edson G. Soares
Pages: 1027-1036
Published online on: 01 April 2010

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Article

Up-regulated expression of stathmin may be associated with hepatocarcinogenesis

Lin Gan, Kun Guo, Yan Li, Xiaonan Kang, Lu Sun, Hong Shu, Yinkun Liu
Pages: 1037-1043
Published online on: 01 April 2010

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Article

Co-expression of the androgen receptor and the transcription factor ZNF652 is related to prostate cancer outcome

David F. Callen, Carmela Ricciardelli, Miriam Butler, Alan Stapleton, Jurgen Stahl, James G. Kench, David J. Horsfall, Wayne D. Tilley, Renee Schulz, Jahn M. Nesland, Paul M. Neilsen, Raman Kumar, Ruth Holm
Pages: 1045-1052
Published online on: 01 April 2010

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Article

Cyclosporin A and sanglifehrin A enhance chemotherapeutic effect of cisplatin in C6 glioma cells

Xuezhe Han, Sung H. Yoon, Yan Ding, Tae G. Choi, Won J. Choi, Yun H. Kim, Young-Joo Kim, Young-Buhm Huh, Joohun Ha, Sung S. Kim
Pages: 1053-1062
Published online on: 01 April 2010

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Article

The universal overexpression of a cancer testis antigen hiwi is associated with cancer angiogenesis

Shuang Li, Li Meng, Changhong Zhu, Li Wu, Xiangyang Bai, Juncheng Wei, Yunping Lu, Jianfeng Zhou, Ding Ma
Pages: 1063-1068
Published online on: 01 April 2010

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Article Open Access

Use of 18F-fluorodeoxyglucose positron emission tomography for diagnosis of uterine sarcomas

Akira Nagamatsu, Naohiko Umesaki, Li Li, Tetsuji Tanaka
Pages: 1069-1076
Published online on: 01 April 2010

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Article Open Access

Hyperthermic isolated limb perfusion for recurrent melanomas and soft tissue sarcomas: Feasibility and reproducibility in a multi-institutional Hellenic collaborative study

Konstantinos Lasithiotakis, George Economou, Helen Gogas, Christos Ioannou, Konstantinos Perisynakis, Dimitrios Filis, Ourania Kastana, Dimitrios Bafaloukos, Marios Decatris, Nikolaos Catodritis, Konstantina Frangia, George Papadakis, Michael Magarakis, Dimosthenis Tsoutsos, Emmanuel Chrysos, George Chalkiadakis, Odysseas Zoras
Pages: 1077-1083
Published online on: 01 April 2010

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Article

Human papillomavirus is frequently detected in gefitinib-responsive lung adenocarcinomas

Michihiro Baba, Andres Castillo, Chihaya Koriyama, Masakazu Yanagi, Hidehiko Matsumoto, Shoji Natsugoe, Karem Y. Shuyama, Noureen Khan, Michiyo Higashi, Tetsuhiko Itoh, Yoshito Eizuru, Takashi Aikou, Suminori Akiba
Pages: 1085-1092
Published online on: 01 April 2010

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Article Open Access

Persistence of HPV after radio-chemotherapy in locally advanced cervical cancer

Gianna Badaracco, Antonella Savarese, Adriana Micheli, Consuelo Rizzo, Francesca Paolini, Mariantonia Carosi, Giuseppe Cutillo, Enrico Vizza, Giorgio Arcangeli, Aldo Venuti
Pages: 1093-1099
Published online on: 01 April 2010

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Article

Hypomethylation-induced expression of S100A4 increases the invasiveness of laryngeal squamous cell carcinoma

Jia Liu, Yan Guo, Shuang Fu, Min Yang, Kai-Lai Sun, Wei-Neng Fu
Pages: 1101-1107
Published online on: 01 April 2010

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Article

The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells

Lei Wang, Zhao-Yi Wang
Pages: 1109-1117
Published online on: 01 April 2010

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Article

Correlation between pathological data and the RNA expression of p53 or p53-targeted genes in primary invasive ductal breast carcinomas: A preliminary study

Loredana Albonici, Roberto P. Sorge, Giuseppe Santeusanio, Paolo Garofano, Vittorio Manzari, Giovanni Barillari
Pages: 1119-1123
Published online on: 01 April 2010

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Article

The prognostic value of cadherin switch in bladder cancer

Tobias Jäger, Markus Becker, Andreas Eisenhardt, Derya Tilki, Martin Tötsch, Kurt W. Schmid, Imre Romics, Herbert Rübben, Süleyman Ergün, Tibor Szarvas
Pages: 1125-1132
Published online on: 01 April 2010

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Article

p38 MAPK plays a distinct role in sulforaphane-induced up-regulation of ARE-dependent enzymes and down-regulation of COX-2 in human bladder cancer cells

Yujuan Shan, Xiaoxue Wang, Wei Wang, Canxia He, Yongping Bao
Pages: 1133-1138
Published online on: 01 April 2010

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Article

Dexamethasone treatment inhibits VEGF production via suppression of STAT3 in a head and neck cancer cell line

Seon-Hui Shim, J. Hun Hah, So-Yeon Hwang, Dae Seog Heo, Myung-Whun Sung
Pages: 1139-1143
Published online on: 01 April 2010

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Article

Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of α-tubulin

Manuela Gridling, Ruxandra Popescu, Brigitte Kopp, Karl-Heinz Wagner, Liselotte Krenn, Georg Krupitza
Pages: 1145-1151
Published online on: 01 April 2010

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Article

Propyl gallate inhibits the growth of HeLa cells via caspase-dependent apoptosis as well as a G1 phase arrest of the cell cycle

Yong Hwan Han, Hwa Jin Moon, Bo Ra You, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Pages: 1153-1158
Published online on: 01 April 2010

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Article

The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines

Eduardo Parra, Jorge Ferreira
Pages: 1159-1165
Published online on: 01 April 2010

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Article

RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer

Zhi Gang Wang, Takuya Fukazawa, Toshio Nishikawa, Nobuyuki Watanabe, Kazufumi Sakurama, Takayuki Motoki, Shinji Hatakeyama, Osamu Omori, Toshiaki Ohara, Shunsuke Tanabe, Yasuhiro Fujiwara, Munenori Takaoka, Yasuhiro Shirakawa, Tomoki Yamatsuji, Noriaki Tanaka, Yoshio Naomoto
Pages: 1167-1172
Published online on: 01 April 2010

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Article

Inhibitory effects of melatonin on sulfatase and 17β-hydroxysteroid dehydrogenase activity and expression in glioma cells

Alicia González, Carlos Martínez-Campa, Maria Dolores Mediavilla, Carolina Alonso-González, Virginia Álvarez-García, Emilio José Sánchez-Barceló, Samuel Cos
Pages: 1173-1178
Published online on: 01 April 2010

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
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