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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2010 Volume 23 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis (Review)

Anna Chiarini, James F. Whitfield, Raffaella Pacchiana, Maddalena Marconi, Ubaldo Armato, Ilaria Dal Prà
Pages: 887-892
Published online on: 01 April 2010

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Article

RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer

Shaolei Zang, Feng Chen, Jianjian Dai, Dongmei Guo, William Tse, Xun Qu, Daoxin Ma, Chunyan Ji
Pages: 893-899
Published online on: 01 April 2010

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Article

Promotion of melanoma growth by the metabolic hormone leptin

Julie A. Ellerhorst, A. H. Diwan, Shyam M. Dang, Deon G. Uffort, Marilyn K. Johnson, Carolyn P. Cooke, Elizabeth A. Grimm
Pages: 901-907
Published online on: 01 April 2010

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Article

Expression of the HER-1-4 family of receptor tyrosine kinases in neuroendocrine tumours

Rajaventhan Srirajaskanthan, Tahir Shah, Jennifer Watkins, Laura Marelli, Korsa Khan, Martyn E. Caplin
Pages: 909-915
Published online on: 01 April 2010

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Article

Clinical significance of syndecan-1 and versican expression in human epithelial ovarian cancer

Tomoyuki Kusumoto, Junichi Kodama, Noriko Seki, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu
Pages: 917-925
Published online on: 01 April 2010

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Article

Claudin expression profiles in Epstein-Barr virus-associated nasopharyngeal carcinoma

Fumiyoshi Kojima, Mitsuaki Ishida, Mikiko Takikita-Suzuki, Machiko Hotta, Kanade Katsura, Akihiro Nagata, Yasuyuki Enoki, Gen-Ichi Kato, Hidetoshi Okabe
Pages: 927-931
Published online on: 01 April 2010

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Article

HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis

Nobuyuki Bandoh, Takeshi Ogino, Akihiro Katayama, Miki Takahara, Akihiro Katada, Tatsuya Hayashi, Yasuaki Harabuchi
Pages: 933-939
Published online on: 01 April 2010

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Article

The angiotensin-converting enzyme 2 in tumor growth and tumor-associated angiogenesis in non-small cell lung cancer

Yun Feng, Huanying Wan, Jialin Liu, Ruifeng Zhang, Qinyun Ma, Bing Han, Yi Xiang, Jiaming Che, Huangming Cao, Xiaochun Fei, Weicheng Qiu
Pages: 941-948
Published online on: 01 April 2010

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Article

Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer

Soichiro Tsunemi, Toyofumi Nakanishi, Yoshihisa Fujita, George Bouras, Yoshiharu Miyamoto, Akiko Miyamoto, Eiji Nomura, Takayuki Takubo, Nobuhiko Tanigawa
Pages: 949-956
Published online on: 01 April 2010

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Article

Antitumor effects of lapatinib (GW572016), a dual inhibitor of EGFR and HER-2, in combination with cisplatin or paclitaxel on head and neck squamous cell carcinoma

Norio Kondo, Mamoru Tsukuda, Yukari Ishiguro, Machiko Kimura, Kyoko Fujita, Atsuko Sakakibara, Hideaki Takahashi, Gabor Toth, Hideki Matsuda
Pages: 957-963
Published online on: 01 April 2010

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Article

Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma

Pavel V. Korita, Toshifumi Wakai, Yoshio Shirai, Yasunobu Matsuda, Jun Sakata, Masaaki Takamura, Masahiko Yano, Ayumi Sanpei, Yutaka Aoyagi, Katsuyoshi Hatakeyama, Yoichi Ajioka
Pages: 965-972
Published online on: 01 April 2010

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Article

The expression of NAD(P)H:quinone oxidoreductase 1 is increased along with NF-κB p105/p50 in human cutaneous melanomas

Yabin Cheng, Jun Li, Magdalena Martinka, Gang Li
Pages: 973-979
Published online on: 01 April 2010

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Article

Intratumoral injection of pEGFC1-IGFBP7 inhibits malignant melanoma growth in C57BL/6J mice by inducing apoptosis and down-regulating VEGF expression

Rong-Yi Chen, Hong-Xiang Chen, Ping Jian, Li Xu, Juan Li, Yi-Ming Fan, Ya-Ting Tu
Pages: 981-988
Published online on: 01 April 2010

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Article

Prognostic significance of insulin growth factor-I receptor and insulin growth factor binding protein-3 expression in primary breast cancer

Jun H. Kim, Young H. Cho, Yong L. Park, Jin H. Sohn, Hee S. Kim
Pages: 989-995
Published online on: 01 April 2010

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Article

MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2

Gong Chen, Wei Zhu, Dezhi Shi, Li Lv, Chun Zhang, Ping Liu, Weixing Hu
Pages: 997-1003
Published online on: 01 April 2010

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Article

The effect on radioresistance of manganese superoxide dismutase in nasopharyngeal carcinoma

Yaming Qu, Hua Zhang, Suping Zhao, Jidong Hong, Cane Tang
Pages: 1005-1011
Published online on: 01 April 2010

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Article

RNA interference-mediated hTERT inhibition enhances TRAIL-induced apoptosis in resistant hepatocellular carcinoma cells

Ru-Gang Zhang, Jing-Jing Zhao, Liu-Qin Yang, Shi-Ming Yang, Rong-Quan Wang, Wen-Sheng Chen, Gui-Yong Peng, Dian-Chun Fang
Pages: 1013-1019
Published online on: 01 April 2010

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Article

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

Gregory T. Langland, Steven M. Yannone, Rachel A. Langland, Aki Nakao, Yinghui Guan, Sydney B.T. Long, Lien Vonguyen, David J. Chen, Joe W. Gray, Fanqing Chen
Pages: 1021-1026
Published online on: 01 April 2010

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Article

BUBR1 expression in benign oral lesions and squamous cell carcinomas: Correlation with human papillomavirus

Régia C.P. Lira, Fabiana A. Miranda, Márcia C.M. Guimarães, Renata T. Simões, Eduardo A. Donadi, Christiane P. Soares, Edson G. Soares
Pages: 1027-1036
Published online on: 01 April 2010

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Article

Up-regulated expression of stathmin may be associated with hepatocarcinogenesis

Lin Gan, Kun Guo, Yan Li, Xiaonan Kang, Lu Sun, Hong Shu, Yinkun Liu
Pages: 1037-1043
Published online on: 01 April 2010

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Article

Co-expression of the androgen receptor and the transcription factor ZNF652 is related to prostate cancer outcome

David F. Callen, Carmela Ricciardelli, Miriam Butler, Alan Stapleton, Jurgen Stahl, James G. Kench, David J. Horsfall, Wayne D. Tilley, Renee Schulz, Jahn M. Nesland, Paul M. Neilsen, Raman Kumar, Ruth Holm
Pages: 1045-1052
Published online on: 01 April 2010

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Article

Cyclosporin A and sanglifehrin A enhance chemotherapeutic effect of cisplatin in C6 glioma cells

Xuezhe Han, Sung H. Yoon, Yan Ding, Tae G. Choi, Won J. Choi, Yun H. Kim, Young-Joo Kim, Young-Buhm Huh, Joohun Ha, Sung S. Kim
Pages: 1053-1062
Published online on: 01 April 2010

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Article

The universal overexpression of a cancer testis antigen hiwi is associated with cancer angiogenesis

Shuang Li, Li Meng, Changhong Zhu, Li Wu, Xiangyang Bai, Juncheng Wei, Yunping Lu, Jianfeng Zhou, Ding Ma
Pages: 1063-1068
Published online on: 01 April 2010

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Article Open Access

Use of 18F-fluorodeoxyglucose positron emission tomography for diagnosis of uterine sarcomas

Akira Nagamatsu, Naohiko Umesaki, Li Li, Tetsuji Tanaka
Pages: 1069-1076
Published online on: 01 April 2010

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Article Open Access

Hyperthermic isolated limb perfusion for recurrent melanomas and soft tissue sarcomas: Feasibility and reproducibility in a multi-institutional Hellenic collaborative study

Konstantinos Lasithiotakis, George Economou, Helen Gogas, Christos Ioannou, Konstantinos Perisynakis, Dimitrios Filis, Ourania Kastana, Dimitrios Bafaloukos, Marios Decatris, Nikolaos Catodritis, Konstantina Frangia, George Papadakis, Michael Magarakis, Dimosthenis Tsoutsos, Emmanuel Chrysos, George Chalkiadakis, Odysseas Zoras
Pages: 1077-1083
Published online on: 01 April 2010

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Article

Human papillomavirus is frequently detected in gefitinib-responsive lung adenocarcinomas

Michihiro Baba, Andres Castillo, Chihaya Koriyama, Masakazu Yanagi, Hidehiko Matsumoto, Shoji Natsugoe, Karem Y. Shuyama, Noureen Khan, Michiyo Higashi, Tetsuhiko Itoh, Yoshito Eizuru, Takashi Aikou, Suminori Akiba
Pages: 1085-1092
Published online on: 01 April 2010

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Article Open Access

Persistence of HPV after radio-chemotherapy in locally advanced cervical cancer

Gianna Badaracco, Antonella Savarese, Adriana Micheli, Consuelo Rizzo, Francesca Paolini, Mariantonia Carosi, Giuseppe Cutillo, Enrico Vizza, Giorgio Arcangeli, Aldo Venuti
Pages: 1093-1099
Published online on: 01 April 2010

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Article

Hypomethylation-induced expression of S100A4 increases the invasiveness of laryngeal squamous cell carcinoma

Jia Liu, Yan Guo, Shuang Fu, Min Yang, Kai-Lai Sun, Wei-Neng Fu
Pages: 1101-1107
Published online on: 01 April 2010

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Article

The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells

Lei Wang, Zhao-Yi Wang
Pages: 1109-1117
Published online on: 01 April 2010

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Article

Correlation between pathological data and the RNA expression of p53 or p53-targeted genes in primary invasive ductal breast carcinomas: A preliminary study

Loredana Albonici, Roberto P. Sorge, Giuseppe Santeusanio, Paolo Garofano, Vittorio Manzari, Giovanni Barillari
Pages: 1119-1123
Published online on: 01 April 2010

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Article

The prognostic value of cadherin switch in bladder cancer

Tobias Jäger, Markus Becker, Andreas Eisenhardt, Derya Tilki, Martin Tötsch, Kurt W. Schmid, Imre Romics, Herbert Rübben, Süleyman Ergün, Tibor Szarvas
Pages: 1125-1132
Published online on: 01 April 2010

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Article

p38 MAPK plays a distinct role in sulforaphane-induced up-regulation of ARE-dependent enzymes and down-regulation of COX-2 in human bladder cancer cells

Yujuan Shan, Xiaoxue Wang, Wei Wang, Canxia He, Yongping Bao
Pages: 1133-1138
Published online on: 01 April 2010

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Article

Dexamethasone treatment inhibits VEGF production via suppression of STAT3 in a head and neck cancer cell line

Seon-Hui Shim, J. Hun Hah, So-Yeon Hwang, Dae Seog Heo, Myung-Whun Sung
Pages: 1139-1143
Published online on: 01 April 2010

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Article

Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of α-tubulin

Manuela Gridling, Ruxandra Popescu, Brigitte Kopp, Karl-Heinz Wagner, Liselotte Krenn, Georg Krupitza
Pages: 1145-1151
Published online on: 01 April 2010

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Article

Propyl gallate inhibits the growth of HeLa cells via caspase-dependent apoptosis as well as a G1 phase arrest of the cell cycle

Yong Hwan Han, Hwa Jin Moon, Bo Ra You, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Pages: 1153-1158
Published online on: 01 April 2010

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Article

The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines

Eduardo Parra, Jorge Ferreira
Pages: 1159-1165
Published online on: 01 April 2010

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Article

RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer

Zhi Gang Wang, Takuya Fukazawa, Toshio Nishikawa, Nobuyuki Watanabe, Kazufumi Sakurama, Takayuki Motoki, Shinji Hatakeyama, Osamu Omori, Toshiaki Ohara, Shunsuke Tanabe, Yasuhiro Fujiwara, Munenori Takaoka, Yasuhiro Shirakawa, Tomoki Yamatsuji, Noriaki Tanaka, Yoshio Naomoto
Pages: 1167-1172
Published online on: 01 April 2010

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Article

Inhibitory effects of melatonin on sulfatase and 17β-hydroxysteroid dehydrogenase activity and expression in glioma cells

Alicia González, Carlos Martínez-Campa, Maria Dolores Mediavilla, Carolina Alonso-González, Virginia Álvarez-García, Emilio José Sánchez-Barceló, Samuel Cos
Pages: 1173-1178
Published online on: 01 April 2010

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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