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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2010 Volume 24 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Male breast cancer: Risk factors, diagnosis, and management (Review)

Katherine A. Johansen Taber, Lee R. Morisy, Albert J. Osbahr, Barry D. Dickinson
Pages: 1115-1120
Published online on: 01 November 2010

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Article

Chemotherapy for breast cancer (Review)

M. S.U. Hassan, J. Ansari, D. Spooner, S. A. Hussain
Pages: 1121-1131
Published online on: 01 November 2010

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Article Open Access

Characterization of an alternative transcript of the human CREB3L2 gene

Ioannis Panagopoulos, Nastaran Monsef, Anna Collin, Fredrik Mertens
Pages: 1133-1139
Published online on: 01 November 2010

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Article Open Access

Schedule-dependent antitumor activity of the combination with erlotinib and docetaxel in human non-small cell lung cancer cells with EGFR mutation, KRAS mutation or both wild-type EGFR and KRAS

Koh Furugaki, Toshiki Iwai, Masatoshi Shirane, Kumiko Kondoh, Yoichiro Moriya, Kazushige Mori
Pages: 1141-1146
Published online on: 01 November 2010

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Article Open Access

Analogy between sphere forming ability and stemness of human hepatoma cells

Yusuke Uchida, Shinji Tanaka, Arihiro Aihara, Rama Adikrisna, Kenichirou Yoshitake, Satoshi Matsumura, Yusuke Mitsunori, Ayano Murakata, Norio Noguchi, Takumi Irie, Atsushi Kudo, Noriaki Nakamura, Paul B. Lai, Shigeki Arii
Pages: 1147-1151
Published online on: 01 November 2010

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Article

Scutellarin inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells

Haixia Li, Dayong Huang, Zhongxiuzi Gao, Yanhong Lv, Lina Zhang, Haidong Cui, Jinhua Zheng
Pages: 1153-1160
Published online on: 01 November 2010

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Article

Non-surgical care for locally advanced breast cancer: Radiologically assessed therapeutic outcome of a new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II) with systemic chemotherapy

Kana Miyatake, Kei Kubota, Yasuhiro Ogawa, Norihiko Hamada, Yoriko Murata, Akihito Nishioka
Pages: 1161-1168
Published online on: 01 November 2010

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Article

Induction of apoptosis by HAC-Y6, a novel microtubule inhibitor, through activation of the death receptor 4 signaling pathway in human hepatocellular carcinoma cells

Jui-Ying Tsai, Chao-Ming Hung, Shih-Ting Bai, Chi-Hung Huang, Wei-Chih Chen, Jinh-Gung Chung, Sheng-Chu Kuo, Tzong-Der Way, Li-Jiau Huang
Pages: 1169-1178
Published online on: 01 November 2010

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Article

Expression of urotensin II and its receptor in human lung adenocarcinoma A549 cells and the effect of urotensin II on lung adenocarcinoma growth in vitro and in vivo

Yu-Qing Wu, Zheng Song, Cheng-Hua Zhou, Shu-Hua Xing, Dong-Sheng Pei, Jun-Nian Zheng
Pages: 1179-1184
Published online on: 01 November 2010

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Article

Discrepancy of biologic behavior influenced by bone marrow derived cells in lung cancer

Jie Zhang, Xiao-Min Niu, Mei-Lin Liao, Yun Liu, Hui-Fang Sha, Yi Zhao, Yong-Feng Yu, Qiang Tan, Jia-Qing Xiang, Jing Fang, Dan-Dan Lv, Xue-Bing Li, Shun Lu, Hai-Quan Chen
Pages: 1185-1192
Published online on: 01 November 2010

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Article

Regulation of apoptosis by p53-inducible transmembrane protein containing sushi domain

Hongyan Cui, Hiroki Kamino, Yasuyuki Nakamura, Noriaki Kitamura, Takafumi Miyamoto, Daisuke Shinogi, Olga Goda, Hirofumi Arakara, Manabu Futamura
Pages: 1193-1200
Published online on: 01 November 2010

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Article

Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients

Shusaku Takahashi, Toshiya Kamiyama, Utano Tomaru, Akihiro Ishizu, Toshiyuki Shida, Mineji Osaka, Yutaka Sato, Yutaka Saji, Michitaka Ozaki, Satoru Todo
Pages: 1201-1212
Published online on: 01 November 2010

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Article

Induction chemotherapy with TPF (Docetaxel, Carboplatin and Fluorouracil) in the treatment of locally advanced squamous cell carcinoma of the head and neck

J. D. Schultz, G. Bran, C. Anders, H. Sadick, A. Faber, K. Hörmann, A. Sauter
Pages: 1213-1216
Published online on: 01 November 2010

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Article

Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway

Jian Zhang, Yongping Du, Changgui Wu, Xinling Ren, Xinyu Ti, Jieran Shi, Feng Zhao, Hong Yin
Pages: 1217-1223
Published online on: 01 November 2010

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Article

Differential expression of hedgehog signaling components and Snail/E-cadherin in human brain tumors

Chia-Hua Chou, Ann-Shung Lieu, Chia-Hung Wu, Li-Kwan Chang, Joon-Khim Loh, Run-Chin Lin, Wei-Jay Chen, Huei-De Liao, Wen-Shane Fu, Chung-Shing Chang, Ching-Chih Lin, Ching-Mei Hsu, Chung-Ching Chio, Shen-Long Howng, Yi-Ren Hong
Pages: 1225-1232
Published online on: 01 November 2010

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Article

Loss of ERα and FOXA1 expression in a progression model of luminal type breast cancer: Insights from PyMT transgenic mouse model

Kasi McCune, Rutika Mehta, Mangesh A. Thorat, Sunil Badve, Harikrishna Nakshatri
Pages: 1233-1239
Published online on: 01 November 2010

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Article

MMP13 is a potential prognostic marker for colorectal cancer

Ming-Yii Huang, Hui-Jen Chang, Fu-Yen Chung, Ming-Je Yang, Yu-Hsiang Yang, Jaw-Yuan Wang, Shiu-Ru Lin
Pages: 1241-1247
Published online on: 01 November 2010

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Article

Induction of a less aggressive phenotype in human colon carcinoma HCT116 cells by chronic exposure to HDAC inhibitor SAHA

Alessandro Bressan, Mario Bigioni, Daniela Bellarosa, Federica Nardelli, Clelia Irrissuto, Carlo Alberto Maggi, Monica Binaschi
Pages: 1249-1255
Published online on: 01 November 2010

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Article

The distribution and expression profiles of human Aspartyl/Asparaginyl beta-hydroxylase in tumor cell lines and human tissues

Hui Yang, Kai Song, Tian Xue, Xiao-Ping Xue, Ting Huyan, Wei Wang, Hua Wang
Pages: 1257-1264
Published online on: 01 November 2010

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Article

Overexpression of BDNF and TrkB in human bladder cancer specimens

Pei Chun Lai, Ted H. Chiu, Yen Ta Huang
Pages: 1265-1270
Published online on: 01 November 2010

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Article

Diagnostic value of serum haptoglobin protein as hepatocellular carcinoma candidate marker complementary to α fetoprotein

Hong Shu, Xiaonan Kang, Kun Guo, Shan Li, Mei Li, Lu Sun, Lin Gan, Yinkun Liu, Xue Qin
Pages: 1271-1276
Published online on: 01 November 2010

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Article

A cluster of inflammatory breast cancer (IBC) in an office setting: Additional evidence of the importance of environmental factors in IBC etiology

Tina J. Duke, Nasreen C. Jahed, Carmela C. Veneroso, Ricardo Da Roza, Owen Johnson, Daniel Hoffman, Sanford H. Barsky, Paul H. Levine
Pages: 1277-1284
Published online on: 01 November 2010

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Article

Oncolytic adenovirus mediated Survivin RNA interference and 5-fluorouracil synergistically suppress the lymphatic metastasis of colorectal cancer

Wei Shen, Jing-Kai Tu, Xue-Hu Wang, Zhong-Xue Fu
Pages: 1285-1290
Published online on: 01 November 2010

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Article

erbB2 gene silencing and its effect on PTEN in SACC-83 salivary adenoid cystic carcinoma cells

Xiaohua Liu, Yincheng Zhang, Wenhao Ren, Guozhou Rao
Pages: 1291-1296
Published online on: 01 November 2010

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Article

Replication-dependent γ-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells

Feng Zhang, Tao Zhang, Yang Qu, Tao Jiang, Yun-Xin Cao, Chen Li, Lei Fan, Qi-Bing Mei
Pages: 1297-1305
Published online on: 01 November 2010

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Article

Gimeracil, a component of S-1, may enhance the antitumor activity of X-ray irradiation in human cancer xenograft models in vivo

Masakazu Fukushima, Kazuki Sakamoto, Minoru Sakata, Fumio Nakagawa, Hitoshi Saito, Yu Sakata
Pages: 1307-1313
Published online on: 01 November 2010

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Article

Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells

Joanna C. Pointon, Gina Eagle, James Bailey, Paul Evans, David Allsup, John Greenman
Pages: 1315-1321
Published online on: 01 November 2010

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Article

Vaccination of full-length HPV16 E6 or E7 protein inhibits the growth of HPV16 associated tumors

Yan-Li Li, Xu-Hua Qiu, Chen Shen, Jian-Ning Liu, Jing Zhang
Pages: 1323-1329
Published online on: 01 November 2010

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Article

Estrogen receptor β and epidermal growth factor receptor as early-stage prognostic biomarkers of non-small cell lung cancer

Laura Valeria Mauro, Mercedes Dalurzo, María José Carlini, David Smith, Myriam Nuñez, Marina Simian, José Lastiri, Bartolomé Vasallo, Elisa Bal de Kier Joffé, María Guadalupe Pallotta, Lydia Puricelli
Pages: 1331-1338
Published online on: 01 November 2010

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Article

Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell line growth

Eduardo Parra, Jorge Ferreira
Pages: 1339-1345
Published online on: 01 November 2010

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Article

Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population

Ivona Hlavata, David Vrana, Zdenek Smerhovsky, Barbara Pardini, Alessio Naccarati, Pavel Vodicka, Jan Novotny, Beatrice Mohelnikova-Duchonova, Pavel Soucek
Pages: 1347-1353
Published online on: 01 November 2010

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Article

Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines

Paula Schiapparelli, Mónica Enguita-Germán, Jana Balbuena, Juan A. Rey, Paula Lázcoz, Javier S. Castresana
Pages: 1355-1362
Published online on: 01 November 2010

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Article

microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2

Hao Zhang, Xiaobing Cai, Yang Wang, Hao Tang, Daki Tong, Fang Ji
Pages: 1363-1369
Published online on: 01 November 2010

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Article

A subset of microRNAs potentially acts as a convergent hub for upstream transcription factors in cancer cells

Hiroaki Ohdaira, Tomoe Sasaki, Kenichi Yoshida
Pages: 1371-1381
Published online on: 01 November 2010

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Article

The impact of conventional or hypofractionated radiotherapy on voice quality and oncological outcome in patients with early glottic cancer

L. Di Nicola, G. L. Gravina, F. Marampon, P. Bonfili, S. Buonopane, M. Di Staso, C. Festuccia, P. Franzese, M. Tombolini, V. Tombolini
Pages: 1383-1388
Published online on: 01 November 2010

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Article

Cooperation of actin-sequestering protein, thymosin β-4 and hypoxia inducible factor-1α in tumor cell migration

Yun-Kyoung Ryu, Yun-Sun Im, Eun-Yi Moon
Pages: 1389-1394
Published online on: 01 November 2010

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Article

The antiandrogen bicalutamide activates the androgen receptor (AR) with a mutation in codon 741 through the mitogen activated protein kinase (MARK) pathway in human prostate cancer PC3 cells

Tomoaki Terakawa, Hideaki Miyake, Masafumi Kumano, Iori Sakai, Masato Fujisawa
Pages: 1395-1399
Published online on: 01 November 2010

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Article

Suppressed protein expression of the death-associated protein kinase enhances 5-fluorouracil-sensitivity but not etoposide-sensitivity in human endometrial adenocarcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa
Pages: 1401-1405
Published online on: 01 November 2010

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Research progress on plant polysaccharides in the prevention and treatment of tumors (Review)

Jikun Wang, Yihan Wang, Xiwu Zhang
Article Number: 152
Published online on: 26 June 2026

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Article Open Access

PIN1 inhibits ferroptosis in gastric cancer cells by regulating the CPEB1‑GPX4 pathway

Aoran Zeng, Tao Wang, Jie Song, Lili Zhu, Ling Chen, Qi Yuan, Ying Jiang, Ping Zhang, Shengzhong Rong, Jing Wang
Article Number: 151
Published online on: 24 June 2026

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Review Open Access

Tanshinone IIA in breast cancer: Molecular mechanisms, structural optimization and translational challenges (Review)

Xiuxia Li, Linlin Feng
Article Number: 150
Published online on: 23 June 2026

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Retraction Open Access

[Retracted] Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells

Roberta Napolitano, Serena De Matteis, Silvia Carloni, Samantha Bruno, Giulia Abbati, Laura Capelli, Martina Ghetti, Maria Teresa Bochicchio, Chiara Liverani, Laura Mercatali, Daniele Calistri, Antonio Cuneo, Krishna Menon, Gerardo Musuraca, Giovanni Martinelli, Giorgia Simonetti
Article Number: 149
Published online on: 22 June 2026

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Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Article Open Access

Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

Fengjin Li, Jiacai Fu, Xiaowei Lin, Yanting Liu, Lu Yang, Yuxin Li, Tieli Peng, Ling Qi
Article Number: 147
Published online on: 16 June 2026

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Review

Research advances on DKK1 in head and neck squamous cell carcinoma: Linking molecular mechanisms to clinical applications (Review)

Xiaoqian Zhu, Liwei Hong, Weihan Chen, Junjuan Tan, Juju Zhou, Lingya Yang, Yonglin Liu, Tiantian Zhai, Kai Chen
Article Number: 146
Published online on: 16 June 2026

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Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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