Journal Articles

Open Access

The molecular basis of fertilization (Review)

Katerina Georgadaki, Nikolas Khoury, Demetrios A. Spandidos, Vasilis Zoumpourlis

Pages: 979-986 Published online on: 31 August 2016

Regulatory effects of GRK2 on GPCRs and non-GPCRs and possible use as a drug target (Review)

Chen-Chen Han, Yang Ma, Yifan Li, Yang Wang, Wei Wei

Pages: 987-994 Published online on: 29 August 2016

Oxidative stress in the trabecular meshwork (Review)

Jing Zhao, Shuang Wang, Wei Zhong, Ben Yang, Lixia Sun, Yajuan Zheng

Pages: 995-1002 Published online on: 24 August 2016
Open Access

The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review)

Hongyan Zhou, Wensong Zhang, Miaomiao Bi, Jie Wu

Pages: 1003-1011 Published online on: 04 August 2016
Open Access

Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review)

Silvia Gangemi, Eliza Gofita, Chiara Costa, Michele Teodoro, Giusi Briguglio, Dragana Nikitovic, George Tzanakakis, Aristides M. Tsatsakis, Martin F. Wilks, Demetrios A. Spandidos, Concettina Fenga

Pages: 1012-1020 Published online on: 02 September 2016

Importance of the interaction between immune cells and tumor vasculature mediated by thalidomide in cancer treatment (Review)

Xin Wang, Yanwei Shen, Shuting Li, Meng Lv, Xiaoman Zhang, Jiao Yang, Fan Wang, Jin Yang

Pages: 1021-1029 Published online on: 31 August 2016

Sphingosine 1-phosphate in metabolic syndrome (Review)

Wei Chen, Hongwei Lu, Jie Yang, Hong Xiang, Hui Peng

Pages: 1030-1038 Published online on: 07 September 2016
Open Access

Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis

Hulin Chen, Junling Wang, Zhongrong Liu, Huilan Yang, Yingjie Zhu, Minling Zhao, Yan Liu, Miaomiao Yan

Pages: 1039-1046 Published online on: 03 August 2016
Open Access

5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1

Wenli Li, Dan Wu, Ziyu Niu, Dalei Jiang, Huan Ma, Heming He, Xiuli Zuo, Xiangjun Xie, Yuanlong He

Pages: 1047-1054 Published online on: 11 August 2016
Open Access

Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway

Ying Qian Zhang, Shun Ying Hu, Yun Dai Chen, Ming Zhou Guo, Shan Wang

Pages: 1055-1062 Published online on: 18 August 2016
Open Access

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

Rosana Mateu, Veronika Živicová, Eliška Drobná Krejčí, Miloš Grim, Hynek Strnad, Čestmír Vlček, Michal Kolář, Lukáš Lacina, Peter Gál, Jiří Borský, Karel Smetana Jr, Barbora Dvořánková

Pages: 1063-1074 Published online on: 11 August 2016
Open Access

Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2

Joo-Hyun Shin, Hyo-Jin Jeon, Jihye Park, Mi-Sook Chang

Pages: 1075-1082 Published online on: 01 August 2016
Open Access

Effects of recombinant human adenovirus-p53 on the regression of hepatic fibrosis

Yehong Liu, Puye Yang, Na Chen, Shumei Lin, Min Liu

Pages: 1093-1100 Published online on: 26 August 2016
Open Access

Anti-atherogenic effect of Humulus japonicus in apolipoprotein E-deficient mice

Haian Lim, Jung-Ran Noh, Yong-Hoon Kim, Jung Hwan Hwang, Kyoung-Shim Kim, Dong-Hee Choi, Min-Jeong Go, Sang-Seop Han, Won-Keun Oh, Chul-Ho Lee

Pages: 1101-1110 Published online on: 01 September 2016
Open Access

Targeted next-generation sequencing helps to decipher the genetic and phenotypic heterogeneity of hypertrophic cardiomyopathy

Massimiliano Cecconi, Maria I. Parodi, Francesco Formisano, Paolo Spirito, Camillo Autore, Maria B. Musumeci, Stefano Favale, Cinzia Forleo, Claudio Rapezzi, Elena Biagini, Sabrina Davì, Elisabetta Canepa, Loredana Pennese, Mauro Castagnetta, Dario Degiorgio, Domenico A. Coviello

Pages: 1111-1124 Published online on: 07 September 2016
Open Access

Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL

Rui Xing, Yingjian Zhang, Changhong Li, Lin Sun, Lin Yang, Jinxia Zhao, Xiangyuan Liu

Pages: 1125-1134 Published online on: 30 August 2016
Open Access

Metformin-suppressed differentiation of human visceral preadipocytes: Involvement of microRNAs

Koji Fujita, Hisakazu Iwama, Kyoko Oura, Tomoko Tadokoro, Kayo Hirose, Miwako Watanabe, Teppei Sakamoto, Akiko Katsura, Shima Mimura, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki

Pages: 1135-1140 Published online on: 02 September 2016
Open Access

Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity

Xiao-Hui Li, Yuan-Yuan Deng, Fei Li, Jing-Shan Shi, Qi-Hai Gong

Pages: 1152-1160 Published online on: 09 August 2016
Open Access

Glucagon-like peptide-1 attenuates advanced oxidation protein product-mediated damage in islet microvascular endothelial cells partly through the RAGE pathway

Zhen Zhang, Lei Yang, Lei Lei, Rongping Chen, Hong Chen, Hua Zhang

Pages: 1161-1169 Published online on: 19 August 2016
Open Access

Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis

Yanan Li, Weijie Min, Mengmeng Li, Guosheng Han, Dongwei Dai, Lei Zhang, Xin Chen, Xinglai Wang, Yuhui Zhang, Zhijian Yue, Jianmin Liu

Pages: 1170-1178 Published online on: 26 August 2016
Open Access

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

Guodong Huang, Jianzhen Lv, Tongyu Li, Guoli Huai, Xiang Li, Shaowei Xiang, Longlong Wang, Zhenlin Qin, Jianli Pang, Bingyu Zou, Yi Wang

Pages: 1179-1189 Published online on: 24 August 2016
Open Access

Pro-apoptotic effects of rHSG on C6 glioma cells

Peng Gao, Yourui Zou, Bing Zhang, Shucai Jiang, Wenjiong Hao, Hui Guo, Guojin Huo, Juncheng Wang, Wei Zhao, Bing Shen

Pages: 1190-1198 Published online on: 31 August 2016
Open Access

Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin

Zefeng Zhang, Xiaoling Bu, Hao Chen, Qiyi Wang, Weihong Sha

Pages: 1199-1207 Published online on: 07 September 2016

miR‑221 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑β1/Smad3-induced EMT

Yi‑Chun Wang, Jing‑Shi Liu, Hao‑Ke Tang, Jing Nie, Ji‑Xian Zhu, Ling‑Ling Wen, Qu‑Lian Guo

Pages: 1208-1216 Published online on: 11 August 2016

p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells

Wei Wang, Junjie Tan, Yuhua Xing, Naipeng Kan, Jingyi Ling, Guifu Dong, Gang Liu, Huipeng Chen

Pages: 1217-1224 Published online on: 19 August 2016

Protective effects of miR-25 against hypoxia/reoxygenation‑induced fibrosis and apoptosis of H9c2 cells

Qifang Liu, Yongjin Wang, Tianlun Yang, Wu Wei

Pages: 1225-1234 Published online on: 11 August 2016

Identification of five novel arginine vasopressin gene mutations in patients with familial neurohypophyseal diabetes insipidus

Dan Tian, Jing Cen, Min Nie, Feng Gu

Pages: 1243-1249 Published online on: 11 August 2016

Cathepsin D is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes

Jianlin Liu, Lin Yang, Hongyan Tian, Qiang Ma

Pages: 1257-1263 Published online on: 18 August 2016

Analgesic effects of 1,2,3,4,6-penta-O-galloyl-β-D-glucose in an animal model of lipopolysaccharide-induced pain

Kun Chun, Si-Oh Kim, Sang-Han Lee

Pages: 1264-1270 Published online on: 01 September 2016

Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation

Fu-Zhou Hua, Jun Ying, Jing Zhang, Xi-Feng Wang, Yan-Hui Hu, Ying-Ping Liang, Qin Liu, Guo-Hai Xu

Pages: 1271-1280 Published online on: 25 August 2016

Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet

Youngmin Kim, Mi-Jin Kwon, Jeong-Wook Choi, Min-Kyeong Lee, Chorong Kim, Jaehun Jung, Heny Aprianita, Heesop Nam, Taek-Jeong Nam

Pages: 1281-1288 Published online on: 01 August 2016

Identification of Mycobacterium tuberculosis in the cerebrospinal fluid of patients with meningitis using nested PCR

Nora Rios-Sarabia, Olivia Hernández-González, Jorge González-Y-Merchand, Guadalupe Gordillo, Guillermo Vázquez-Rosales, Leopoldo Muñoz-Pérez, Javier Torres, Carmen Maldonado-Bernal

Pages: 1289-1295 Published online on: 04 August 2016

In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non‑water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines

Tarik Ghadban, André Jessen, Matthias Reeh, Judith L. Dibbern, Sven Mahner, Volkmar Mueller, Ulrich F. Wellner, Cenap Güngör, Jakob R. Izbicki, Yogesh K. Vashist

Pages: 1296-1302 Published online on: 03 August 2016
Open Access

[Corrigendum] TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis

Gang Li, Xuejun Wu, Le Yang, Yuxiang He, Yang Liu, Xing Jin, Hai Yuan

Pages: 1313-1313 Published online on: 17 August 2016
Journal Cover

October 2016
Volume 38 Issue 4

Print ISSN: 1107-3756
Online ISSN: 1791-244X

2015 Impact Factor: 2.348
Ranked #22/123 Medicine Research and Experimental
(total number of cites)

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