Journal Articles

Open Access

Personalized regulation of glioblastoma cancer stem cells based on biomedical technologies: From theory to experiment (Review)

Igor Bryukhovetskiy, Arina Ponomarenko, Irina Lyakhova, Sergey Zaitsev, Yulia Zayats, Maria Korneyko, Marina Eliseikina, Polina Mischenko, Valerie Shevchenko, Hari Shanker Sharma, Aruna Sharma, Yuri Khotimchenko

Pages: 691-702 Published online on: 10 May 2018
Open Access

CTLA‑4 interferes with the HBV‑specific T cell immune response (Review)

Hui Cao, Ruiwen Zhang, Wei Zhang

Pages: 703-712 Published online on: 17 May 2018
Open Access

Antibacterial and antioxidant activity of different types of honey derived from Mount Olympus in Greece

Dimitrios Stagos, Nikolaos Soulitsiotis, Christina Tsadila, Stamatina Papaeconomou, Charalampos Arvanitis, Alexandros Ntontos, Fani Karkanta, Soultana Adamou‑Androulaki, Konstantinos Petrotos, Demetrios A. Spandidos, Demetrios Kouretas, Dimitris Mossialos

Pages: 726-734 Published online on: 04 May 2018
Open Access

Comparative whole genome transcriptome analysis and fenugreek leaf extract modulation on cadmium‑induced toxicity in liver cells

Caroline Odewumi, Lekan M. Latinwo, Roy Leonard Lyles, Veera L.D. Badisa, Cobb‑Abdullah Ahkinyala, Marijo Kent‑First

Pages: 735-744 Published online on: 10 May 2018
Open Access

Breviscapine ameliorates CCl4‑induced liver injury in mice through inhibiting inflammatory apoptotic response and ROS generation

Yu Liu, Pei‑Hao Wen, Xin‑Xue Zhang, Yang Dai, Qiang He

Pages: 755-768 Published online on: 02 May 2018
Open Access

Xanthatin inhibits corneal neovascularization by inhibiting the VEGFR2‑mediated STAT3/PI3K/Akt signaling pathway

Mei Shen, Xue‑Zhi Zhou, Lei Ye, Qing Yuan, Ce Shi, Pei‑Wen Zhu, Nan Jiang, Ming‑Yang Ma, Qi‑Chen Yang, Yi Shao

Pages: 769-778 Published online on: 30 April 2018
Open Access

Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis

Eun‑Young Kim, Youn Hee Choi, Taek‑Jeong Nam

Pages: 789-798 Published online on: 30 April 2018
Open Access

High glucose suppresses the viability and proliferation of HTR‑8/SVneo cells through regulation of the miR‑137/PRKAA1/IL‑6 axis

Hai‑Yan Peng, Ming‑Qing Li, Hua‑Ping Li

Pages: 799-810 Published online on: 17 May 2018
Open Access

Anti‑cancer effects of fisetin on mammary carcinoma cells via regulation of the PI3K/Akt/mTOR pathway: In vitro and in vivo studies

Xu Sun, Xueman Ma, Qiwei Li, Yong Yang, Xiaolong Xu, Jiaqi Sun, Mingwei Yu, Kexin Cao, Lin Yang, Guowang Yang, Ganlin Zhang, Xiaomin Wang

Pages: 811-820 Published online on: 02 May 2018
Open Access

Expression of annexin II and stromal tenascin C promotes epithelial to mesenchymal transition and correlates with distant metastasis in pancreatic cancer

Naoko Yoneura, Shigetsugu Takano, Hideyuki Yoshitomi, Yasuyuki Nakata, Reiri Shimazaki, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Masaru Miyazaki, Masayuki Ohtsuka

Pages: 821-830 Published online on: 02 May 2018
Open Access

Icariin promotes wound healing by enhancing the migration and proliferation of keratinocytes via the AKT and ERK signaling pathway

Bobin Mi, Jing Liu, Guohui Liu, Wu Zhou, Yi Liu, Liangcong Hu, Liming Xiong, Shunan Ye, Yongchao Wu

Pages: 831-838 Published online on: 14 May 2018
Open Access

miR‑133b regulates proliferation and apoptosis in high‑glucose‑induced human retinal endothelial cells by targeting ras homolog family member A

Jun Yao, Jihong Wang, Yong Yao, Kelei Wang, Qianqian Zhou, Ying Tang

Pages: 839-850 Published online on: 18 May 2018
Open Access

Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang

Pages: 851-860 Published online on: 09 May 2018
Open Access

Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype

Yushu Li, Xingzhi Wang, Lei Zhang, Xueying Yuan, Jianbing Hao, Jie Ni, Lirong Hao

Pages: 861-872 Published online on: 10 May 2018
Open Access

Correlation between the expression of IL‑18 and deep venous thrombosis

Guangdi Li, Rudan Zhou, Xueling Zhao, Riguang Liu, Chuan Ye

Pages: 883-896 Published online on: 16 May 2018
Open Access

Role of TGF‑β1 expressed in bone marrow‑derived mesenchymal stem cells in promoting bone formation in a rabbit femoral defect model

Bing‑Yin Sun, Bao‑Xiang Zhao, Jie‑Ying Zhu, Zheng‑Ping Sun, Yong‑An Shi, Feng Huang

Pages: 897-904 Published online on: 17 May 2018
Open Access

GSK3β‑mediated Ser156 phosphorylation modulates a BH3‑like domain in BCL2L12 during TMZ‑induced apoptosis and autophagy in glioma cells

Cheng‑Wei Chu, Ming‑Chang Yang, Chia‑Hua Chou, Wen‑Sheng Huang, Bo‑Xiu Hsiao, Yeng‑Tseng Wang, Shean‑Jaw Chiou, Joon‑Khim Loh, Yi‑Ren Hong

Pages: 905-918 Published online on: 11 May 2018
Open Access

Knockdown of TNF‑α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL‑10 expression

Zhen Yang, Xue‑Rong Zhang, Qiong Zhao, Sheng‑Lan Wang, Liu‑Lin Xiong, Piao Zhang, Bing Yuan, Zi‑Bing Zhang, Shu‑Yuan Fan, Ting‑Hua Wang, Yun‑Hui Zhang

Pages: 926-934 Published online on: 14 May 2018
Open Access

Role of TXNDC5 in tumorigenesis of colorectal cancer cells: In vivo and in vitro evidence

Fengbo Tan, Hong Zhu, Xiao He, Nanhui Yu, Xingwen Zhang, Haifan Xu, Haiping Pei

Pages: 935-945 Published online on: 09 May 2018
Open Access

Enhanced proliferation and differentiation of HO-1 gene-modified bone marrow-derived mesenchymal stem cells in the acute injured kidney

Nanmei Liu, Huiling Wang, Guofeng Han, Jin Cheng, Weifeng Hu, Jinyuan Zhang

Pages: 946-956 Published online on: 11 May 2018
Open Access

Regulation of interferon signaling and HCV‑RNA replication by extracellular matrix

Takuya Kuwashiro, Shinji Iwane, Xia Jinghe, Sachiko Matsuhashi, Yuichiro Eguchi, Keizo Anzai, Kazuma Fujimoto, Toshihiko Mizuta, Naoya Sakamoto, Masanori Ikeda, Nobuyuki Kato, Iwata Ozaki

Pages: 957-965 Published online on: 18 May 2018
Open Access

Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein

Linna Zhang, Huimei Cao, Tao He, Jijuan Yang, Hong Tao, Yin Wang, Qikuan Hu

Pages: 966-974 Published online on: 14 May 2018
Open Access

MicroRNA‑20b‑5p promotes ventricular remodeling by targeting the TGF‑β/Smad signaling pathway in a rat model of ischemia‑reperfusion injury

Zhao‑Guang Liang, Hong Yao, Rong‑Sheng Xie, Chun‑Lin Gong, Ye Tian

Pages: 975-987 Published online on: 18 May 2018

Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li

Pages: 988-997 Published online on: 17 May 2018

miR‑494 inhibits cancer‑initiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2‑positive gastric cancer

Yanxia Yu, Xuejuan Yu, Hong Liu, Qingxun Song, Yongmei Yang

Pages: 998-1007 Published online on: 16 May 2018

MicroRNA‑381/Hes1 is a potential therapeutic target for spinal cord injury

Wendong Ruan, Guangzhi Ning, Shiqing Feng, Shijie Gao, Yan Hao

Pages: 1008-1017 Published online on: 08 May 2018

Cucurbitacin B inhibits tumor angiogenesis by triggering the mitochondrial signaling pathway in endothelial cells

Xian-Mei Piao, Feng Gao, Jiu-Xin Zhu, Li-Juan Wang, Xin Zhao, Xin Li, Miao-Miao Sheng, Yan Zhang

Pages: 1018-1025 Published online on: 30 April 2018

Inhibition of MEK/ERK/STAT3 signaling in oleuropein treatment inhibits myocardial ischemia/reperfusion

Hong‑Xu Jin, Yun‑Hu Zhang, Ruo‑Nan Guo, Su‑Nuan Zhao

Pages: 1034-1043 Published online on: 11 May 2018

Ectromelia virus upregulates the expression of heat shock protein 70 to promote viral replication

Wenyu Cheng, Huaijie Jia, Xiaoxia Wang, Xiaobing He, Qiwang Jin, Jingxin Cao, Zhizhong Jing

Pages: 1044-1053 Published online on: 04 May 2018

CTRP9 ameliorates cellular senescence via PGC‑1α/AMPK signaling in mesenchymal stem cells

Qun Li, Zhangzhang Zhu, Chengde Wang, Lin Cai, Jianglong Lu, Yongchun Wang, Jiadong Xu, Zhipeng Su, Weiming Zheng, Xianbin Chen

Pages: 1054-1063 Published online on: 09 May 2018

DNAJC3 mutation in Thai familial type 2 diabetes mellitus

Sirikul Kulanuwat, Watip Tangjittipokin, Prapaporn Jungtrakoon, Chutima Chanprasert, Jatuporn Sujjitjoon, Ninareeman Binnima, Pa‑Thai Yenchitsomanus, Nattachet Plengvidhya

Pages: 1064-1073 Published online on: 14 May 2018

Upregulated 14‑3‑3β aggravates restenosis by promoting cell migration following vascular injury in diabetic rats with elevated levels of free fatty acids

Lishuai Feng, Chaoran Dou, Jianbo Wang, Chunyu Jiang, Xu Ma, Jingjing Liu

Pages: 1074-1085 Published online on: 11 May 2018

Silencing of miR‑155 suppresses inflammatory responses in psoriasis through inflammasome NLRP3 regulation

Quan Luo, Jingxin Zeng, Wei Li, Ling Lin, Xin Zhou, Xin Tian, Weiyu Liu, Lidan Zhang, Xibao Zhang

Pages: 1086-1095 Published online on: 14 May 2018

BMP‑6 protects retinal pigment epithelial cells from oxidative stress‑induced injury by inhibiting the MAPK signaling pathways

Li Chen, Ming Liu, Yan Luan, Yingfei Liu, Zhichao Zhang, Bo Ma, Xuan Liu, Yong Liu

Pages: 1096-1105 Published online on: 14 May 2018

Luteolin induces myelodysplastic syndrome‑derived cell apoptosis via the p53‑dependent mitochondrial signaling pathway mediated by reactive oxygen species

Weimin Dong, Yan Lin, Yang Cao, Yue Liu, Xiaobao Xie, Weiying Gu

Pages: 1106-1115 Published online on: 18 May 2018

Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis

Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Rudolf Hagen, Thomas Kerkau, Stephan Hackenberg

Pages: 1116-1124 Published online on: 02 May 2018

Connexin 43 reduces susceptibility to sympathetic atrial fibrillation

Beibei Luo, Yifei Yan, Zhiyu Zeng, Zhengnan Zhang, Haide Liu, Hao Liu, Jinyi Li, Weiqiang Huang, Jiangtao Wu, Yan He

Pages: 1125-1133 Published online on: 30 April 2018

Downregulation of microRNA‑34a inhibits oxidized low‑density lipoprotein‑induced apoptosis and oxidative stress in human umbilical vein endothelial cells

Xiaoming Zhong, Peng Li, Juan Li, Ruili He, Guanchang Cheng, Yanming Li

Pages: 1134-1144 Published online on: 09 May 2018

LncRNA uc.48+ is involved in the diabetic immune and inflammatory responses mediated by P2X7 receptor in RAW264.7 macrophages

Hong Wu, Fang Wen, Mei Jiang, Qiang Liu, Yijun Nie

Pages: 1152-1160 Published online on: 09 May 2018

Apelin protects against sepsis‑induced cardiomyopathy by inhibiting the TLR4 and NLRP3 signaling pathways

Qiancheng Luo, Guorong Liu, Guo Chen, Dongfeng Guo, Lei Xu, Min Hang, Mingming Jin

Pages: 1161-1167 Published online on: 09 May 2018

Collagen peptides from soft‑shelled turtle induce calpain‑1 expression and regulate inflammatory cytokine expression in HaCaT human skin keratinocytes

Tetsushi Yamamoto, Saori Nakanishi, Kuniko Mitamura, Atsushi Taga

Pages: 1168-1180 Published online on: 08 May 2018

Efficient delivery of HBV NLS siRNAs into HepG2.2.15 cells for HBV inhibition through novel recombinant preS1‑tP proteins

Yanli Zeng, Zixi Li, Jia Shang, Yi Kang

Pages: 1181-1189 Published online on: 16 May 2018

Protective effects of dehydrocostuslactone on rat hippocampal slice injury induced by oxygen‑glucose deprivation/reoxygenation

Qipeng Zhao, Ailing Chen, Xiaobo Wang, Zhuanzhuan Zhang, Yunsheng Zhao, Yu Huang, Shuanglai Ren, Yafei Zhu

Pages: 1190-1198 Published online on: 17 May 2018
Open Access

[Corrigendum] Protective effect of angiotensin‑(1‑7) against hyperglycaemia‑induced injury in H9c2 cardiomyoblast cells via the PI3K̸Akt signaling pathway

Yi-Ying Yang, Xiu-Ting Sun, Zheng-Xun Li, Wei-Yan Chen, Xiang Wang, Mei-Ling Liang, Hui Shi, Zhi-Sheng Yang, Wu-Tao Zeng

Pages: 1199-1199 Published online on: 07 May 2018
Journal Cover

August 2018
Volume 42 Issue 2

Print ISSN: 1107-3756
Online ISSN: 1791-244X

2016 Impact Factor: 2.341
Ranked #21/128 Medicine Research and Experimental
(total number of cites)

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