Journal Articles

Open Access

Cell-penetrating peptides and their utility in genome function modifications (Review)

Maciej Gagat, Wioletta Zielińska, Alina Grzanka

Pages: 1615-1623 Published online on: 04 October 2017
Open Access

Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review)

Li-Li Fang, Xing-Hui Wang, Bao-Fei Sun, Xiao-Dong Zhang, Xu-Hui Zhu, Zi-Jiang Yu, Heng Luo

Pages: 1624-1630 Published online on: 29 September 2017
Open Access

Hypothermia inhibits the proliferation of bone marrow-derived mesenchymal stem cells and increases tolerance to hypoxia by enhancing SUMOylation

Xiaozhi Liu, Wenbo Ren, Zhongmin Jiang, Zhiguo Su, Xiaofang Ma, Yanxia Li, Rongcai Jiang, Jianning Zhang, Xinyu Yang

Pages: 1631-1638 Published online on: 29 September 2017
Open Access

Angiogenic effects of apigenin on endothelial cells after hypoxia-reoxygenation via the caveolin-1 pathway

Fengxia Tu, Qiongyi Pang, Xiang Chen, Tingting Huang, Meixia Liu, Qiongxiang Zhai

Pages: 1639-1648 Published online on: 28 September 2017
Open Access

Black rice-derived anthocyanins inhibit HER-2-positive breast cancer epithelial-mesenchymal transition-mediated metastasis in vitro by suppressing FAK signaling

Jie Zhou, Yan-Feng Zhu, Xiang-Yan Chen, Bin Han, Fei Li, Jing-Yao Chen, Xiao-Li Peng, Li-Ping Luo, Wei Chen, Xiao-Ping Yu

Pages: 1649-1656 Published online on: 11 October 2017
Open Access

Chondroitin sulfate proteoglycans inhibit the migration and differentiation of oligodendrocyte precursor cells and its counteractive interaction with laminin

Yi Sun, Yingping Deng, Mili Xiao, Lan Hu, Zhihua Li, Chao Chen

Pages: 1657-1668 Published online on: 27 September 2017
Open Access

Betulinic acid induces apoptosis by regulating PI3K/Akt signaling and mitochondrial pathways in human cervical cancer cells

Tao Xu, Qiuying Pang, Yang Wang, Xiufeng Yan

Pages: 1669-1678 Published online on: 28 September 2017
Open Access

Characterization of tree shrew (Tupaia belangeri) interleukin-6 and its expression pattern in response to exogenous challenge

Yuanyuan Han, Xiaomei Sun, Dexuan Kuang, Pinfen Tong, Caixia Lu, Wenguang Wang, Na Li, Yang Chen, Xiaoping Wang, Jiejie Dai, Huatang Zhang

Pages: 1679-1690 Published online on: 02 October 2017
Open Access

SOX4 arrests lung development in rats with hyperoxia‑induced bronchopulmonary dysplasia by controlling EZH2 expression

Bingting Pan, Xindong Xue, Dan Zhang, Mengyun Li, Jianhua Fu

Pages: 1691-1698 Published online on: 03 October 2017
Open Access

Protective effect of autophagy in neural ischemia and hypoxia: Negative regulation of the Wnt/β-catenin pathway

Zhen-Yu Shi, Jie-Xin Deng, Su Fu, Lai Wang, Qiang Wang, Bin Liu, Yong-Qiang Li, Jin-Bo Deng

Pages: 1699-1708 Published online on: 28 September 2017
Open Access

Isoliquiritigenin suppresses IL-1β induced apoptosis and inflammation in chondrocyte-like ATDC5 cells by inhibiting NF-κB and exerts chondroprotective effects on a mouse model of anterior cruciate ligament transection

Baochao Ji, Wentao Guo, Hairong Ma, Boyong Xu, Wenbo Mu, Zhendong Zhang, Abdusami Amat, Li Cao

Pages: 1709-1718 Published online on: 09 October 2017
Open Access

Analysis of miRNA expression profiling in human umbilical vein endothelial cells affected by heat stress

Jie Liu, Guoguo Zhu, Siya Xu, Shixin Liu, Qiping Lu, Zhongzhi Tang

Pages: 1719-1730 Published online on: 05 October 2017
Open Access

Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice

Qing-Tao Meng, Rong Chen, Cheng Chen, Ke Su, Wei Li, Ling-Hua Tang, Hui-Min Liu, Rui Xue, Qian Sun, Yan Leng, Jia-Bao Hou, Yang Wu, Zhong-Yuan Xia

Pages: 1731-1740 Published online on: 02 October 2017
Open Access

Naringin inhibits vascular endothelial cell apoptosis via endoplasmic reticulum stress‑ and mitochondrial‑mediated pathways and promotes intraosseous angiogenesis in ovariectomized rats

Wen‑Ji Shangguan, Yue‑Hui Zhang, Zhan‑Chun Li, Lu‑Min Tang, Jiang Shao, He Li

Pages: 1741-1749 Published online on: 28 September 2017
Open Access

Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response

Wei Sun, Zhaoming Ding, Shengjie Xu, Zhiqiang Su, Hulun Li

Pages: 1750-1758 Published online on: 29 September 2017
Open Access

Hepatic differentiation of human iPSCs in different 3D models: A comparative study

Florian Meier, Nora Freyer, Joanna Brzeszczynska, Fanny Knöspel, Lyle Armstrong, Majlinda Lako, Selina Greuel, Georg Damm, Eva Ludwig-Schwellinger, Ulrich Deschl, James A. Ross, Mario Beilmann, Katrin Zeilinger

Pages: 1759-1771 Published online on: 16 October 2017
Open Access

Astragaloside IV attenuates the H2O2-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway

Xiang Liu, Jun Zhang, Shibo Wang, Jinfu Qiu, Chao Yu

Pages: 1772-1780 Published online on: 27 September 2017
Open Access

Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy

Biao Liang, Ting Xiao, Junrong Long, Maojun Liu, Zining Li, Shengquan Liu, Jun Yang

Pages: 1781-1791 Published online on: 16 October 2017
Open Access

Internal driving factors leading to extrahepatic manifestation of the hepatitis C virus infection

Zhou-Yi Wu, Jian-Rui Li, Meng-Hao Huang, Jun-Jun Cheng, Hu Li, Jin-Hua Chen, Xiao-Qin Lv, Zong-Gen Peng, Jian-Dong Jiang

Pages: 1792-1802 Published online on: 05 October 2017
Open Access

Vaspin protects against LPS‑induced ARDS by inhibiting inflammation, apoptosis and reactive oxygen species generation in pulmonary endothelial cells via the Akt/GSK‑3β pathway

Di Qi, Daoxin Wang, Chunrong Zhang, Xumao Tang, Jing He, Yan Zhao, Wang Deng, Xinyu Deng

Pages: 1803-1817 Published online on: 09 October 2017
Open Access

Altered expression profiles of circular RNA in colorectal cancer tissues from patients with lung metastasis

Yujian Zeng, Yu Xu, Ruo Shu, Liang Sun, Yan Tian, Chengmin Shi, Zhibin Zheng, Kunhua Wang, Huayou Luo

Pages: 1818-1828 Published online on: 16 October 2017
Open Access

High-throughput sequencing reveals novel lincRNA in age-related cataract

Na Zhang, Chunmei Zhang, Xu Wang, Yanhua Qi

Pages: 1829-1839 Published online on: 11 October 2017
Open Access

MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2

Yuqing Liu, Yunjun Li, Zhenxing Ren, Wenwen Si, Yiwei Li, Gang Wei, Wenguang Zhao, Jianhong Zhou, Yage Tian, Dongfeng Chen

Pages: 1851-1859 Published online on: 10 October 2017
Open Access

Insulin-like growth factor binding protein-6 released from human mesenchymal stem cells confers neuronal protection through IGF-1R-mediated signaling

Hyo-Jin Jeon, Jihye Park, Joo-Hyun Shin, Mi-Sook Chang

Pages: 1860-1868 Published online on: 05 October 2017
Open Access

Rivaroxaban attenuates thrombosis by targeting the NF-κB signaling pathway in a rat model of deep venous thrombus

Junhao Ma, Xinxi Li, Yang Wang, Zhenwei Yang, Jun Luo

Pages: 1869-1880 Published online on: 29 September 2017
Open Access

Grape seed proanthocyanidins inhibit the proliferation, migration and invasion of tongue squamous cell carcinoma cells through suppressing the protein kinase B/nuclear factor-κB signaling pathway

Ninggang Yang, Jing Gao, Xin Cheng, Cuilan Hou, Yaya Yang, Yanxin Qiu, Mengrou Xu, Yuan Zhang, Shuangsheng Huang

Pages: 1881-1888 Published online on: 28 September 2017

Puerarin attenuates the daunorubicin-induced apoptosis of H9c2 cells by activating the PI3K/Akt signaling pathway via the inhibition of Ca2+ influx

Weihua Li, Min Lu, Yanhong Zhang, Danqin Xia, Zebin Chen, Linhua Wang, Nina Yin, Zhigang Wang

Pages: 1889-1894 Published online on: 12 October 2017

Prospective lncRNA-miRNA-mRNA regulatory network of long non-coding RNA LINC00968 in non-small cell lung cancer A549 cells: A miRNA microarray and bioinformatics investigation

Dong-Yao Li, Wen-Jie Chen, Lei Luo, Yong-Kun Wang, Jun Shang, Yu Zhang, Gang Chen, Shi-Kang Li

Pages: 1895-1906 Published online on: 12 October 2017

DNA polymerase 5 acetylation by Eso1 is essential for Schizosaccharomyces pombe viability

Zhiming Chen, Hongshi Cao, Yingqiang Lu, Qiang Ren, Liankun Sun

Pages: 1907-1913 Published online on: 16 October 2017

Construction of a Bcl-2-shRNA expression vector and its effect on the mitochondrial apoptosis pathway in SW982 cells

Weidong Zhang, Xinjie Xue, Teng Fu

Pages: 1914-1920 Published online on: 27 September 2017

Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages

Xu-Xin Chen, Lu Tang, Yu-Mei Fu, Yi Wang, Zhi-Hai Han, Ji-Guang Meng

Pages: 1921-1931 Published online on: 28 September 2017

Protective effects of neem (Azadirachta indica A. Juss.) leaf extract against cigarette smoke- and lipopolysaccharide-induced pulmonary inflammation

Jae-Won Lee, Hyung Won Ryu, So-Yeon Park, Hyun Ah Park, Ok-Kyoung Kwon, Heung Joo Yuk, Krishna K. Shrestha, Minwoo Park, Jung Hee Kim, Sangwoo Lee, Sei-Ryang Oh, Kyung-Seop Ahn

Pages: 1932-1940 Published online on: 10 October 2017

Protective effects of compounds from Garcinia mangostana L. (mangosteen) against UVB damage in HaCaT cells and hairless mice

A-Rang Im, Young-Mi Kim, Young-Won Chin, Sungwook Chae

Pages: 1941-1949 Published online on: 13 October 2017

Anti-inhibitory potential of an ethanolic extract of Distromium decumbens on pro-inflammatory cytokine production in Pseudomonas aeruginosa lipopolysaccharide-stimulated nasal polyp-derived fibroblasts

Dae-Sung Lee, Chang-Min Lee, Seong Kook Park, Mi-Jin Yim, Jeong Min Lee, Grace Choi, Jong Su Yoo, Won-Kyo Jung, Saegwang Park, Su-Kil Seo, Won Sun Park, Il-Whan Choi

Pages: 1950-1956 Published online on: 11 October 2017

Phosphorylation of eIF2α suppresses cisplatin-induced p53 activation and apoptosis by attenuating oxidative stress via ATF4-mediated HO-1 expression in human renal proximal tubular cells

Sung-Min Ju, Yong-Seok Jo, Yoo-Min Jeon, Hyun-Ock Pae, Dae-Gill Kang, Ho-Sub Lee, Jun-Sang Bae, Byung-Hun Jeon

Pages: 1957-1964 Published online on: 10 October 2017

RACK1 silencing attenuates renal fibrosis by inhibiting TGF-β signaling

Jie Feng, Liyi Xie, Ranran Kong, Yali Zhang, Kehui Shi, Wanhong Lu, Hongli Jiang

Pages: 1965-1970 Published online on: 27 September 2017

Limited activation of the intrinsic apoptotic pathway plays a main role in amyloid-β-induced apoptosis without eliciting the activation of the extrinsic apoptotic pathway

Md. Imamul Islam, Md. Golam Sharoar, Eun-Kyoung Ryu, Il-Seon Park

Pages: 1971-1982 Published online on: 16 October 2017

The association of LMP7 and TAP2 gene polymorphisms with treatment response to interferon/ribavirin in patients with genotype 1 chronic hepatitis C

Feng Zang, Yinan Yao, Mei Liu, Haozhi Fan, Ming Yue, Mingzhu Chen, Jie Wang, Rongbin Yu, Peng Huang

Pages: 1983-1990 Published online on: 10 October 2017

RUNX3 plays an important role in mediating the BMP9-induced osteogenic differentiation of mesenchymal stem cells

Yufeng Wang, Qiaoling Feng, Caixia Ji, Xiaohua Liu, Li Li, Jinyong Luo

Pages: 1991-1999 Published online on: 27 September 2017

Insulin restores UCP3 activity and decreases energy surfeit to alleviate lipotoxicity in skeletal muscle

Wenjuan Tang, Sunyinyan Tang, Hongdong Wang, Zhijuan Ge, Dalong Zhu, Yan Bi

Pages: 2000-2010 Published online on: 02 October 2017

Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis

Sou Hyun Kim, Dahye Yoon, Yun-Hee Lee, Jaewon Lee, Nam Deuk Kim, Suhkmann Kim, Young-Suk Jung

Pages: 2011-2017 Published online on: 11 October 2017
Journal Cover

December 2017
Volume 40 Issue 6

Print ISSN: 1107-3756
Online ISSN: 1791-244X

2016 Impact Factor: 2.341
Ranked #21/128 Medicine Research and Experimental
(total number of cites)

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