Journal Articles

Open Access

Activation of FXR by obeticholic acid induces hepatic gene expression of SR-BI through a novel mechanism of transcriptional synergy with the nuclear receptor LXR

Bin Dong, Amar B. Singh, Grace L. Guo, Mark Young, Jingwen Liu

Pages: 1927-1938 Published online on: 18 March 2019
Open Access

Effects of miR‑103a‑3p on the autophagy and apoptosis of cardiomyocytes by regulating Atg5

Chenjun Zhang, Jide Lu, Hairong Wang, Yuan Qi, Ying Kan, Zhiru Ge

Pages: 1951-1960 Published online on: 12 March 2019
Open Access

Proteasome activator REGγ promotes inflammation in Leydig cells via IkBε signaling

Tiancheng Xie, Hui Chen, Shihui Shen, Tingmei Huang, Bisheng Huang, Guanghui Hu, Lei Li, Yunfei Xu

Pages: 1961-1968 Published online on: 27 February 2019
Open Access

Honokiol induces apoptosis and suppresses migration and invasion of ovarian carcinoma cells via AMPK/mTOR signaling pathway

Jin Sun Lee, Ji Young Sul, Jun Beom Park, Myung Sun Lee, Eun Young Cha, Young Bok Ko

Pages: 1969-1978 Published online on: 05 March 2019
Open Access

PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1

Bing Huang, Haoran Miao, Yanliang Yuan, Fan Qiu, Xiucheng Liu, Zhiwei Liu, Hu Zhang, Qixiang Zhao, Meng Wang, Hongyan Dong, Zhongming Zhang

Pages: 1979-1990 Published online on: 12 March 2019
Open Access

Isobaric tags for relative and absolute quantitation‑based proteomics reveals potential novel biomarkers for the early diagnosis of acute myocardial infarction within 3 h

Changqing Du, Yingzheng Weng, Jiangjie Lou, Guangzhong Zeng, Xiaowei Liu, Hongfeng Jin, Senna Lin, Lijiang Tang

Pages: 1991-2004 Published online on: 19 March 2019
Open Access

Potential role of the IL17RC gene in the thoracic ossification of the posterior longitudinal ligament

Peng Wang, Xiaoguang Liu, Chao Kong, Xiao Liu, Ze Teng, Yunlong Ma, Lei Yong, Chen Liang, Guanping He, Shibao Lu

Pages: 2005-2014 Published online on: 12 March 2019
Open Access

Molecular interaction of the antiviral compound CW‑33 and its analogues with the NS2B‑NS3 protease of the Japanese encephalitis virus

Kuan‑Chung Chen, Yu‑Fong Lin, An‑Cheng Huang, Jing‑Yang Gao, Cheng‑Wen Lin, Jin‑Cherng Lien

Pages: 2024-2032 Published online on: 27 February 2019
Open Access

Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress

Guiping Luo, Zhao Jian, Yun Zhu, Yu Zhu, Baicheng Chen, Ruiyan Ma, Fuqin Tang, Yingbin Xiao

Pages: 2033-2043 Published online on: 06 March 2019
Open Access

Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression

Haipeng Huang, Yunhong Wu, Weijin Fu, Xiaoming Wang, Liquan Zhou, Xiaolong Xu, Fu Huang, Yi Wu

Pages: 2044-2054 Published online on: 14 March 2019
Open Access

Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt‑SREBP‑2 signaling pathway to influence lipid metabolism in HepG2 cells

Jun Xiao, Xue‑Qin Bai, Ling Liao, Min Zhou, Juan Peng, Qiong Xiang, Zhong Ren, Hong‑Yan Wen, Zhi‑Sheng Jiang, Zhi‑Han Tang, Mei‑Mei Wang, Lu‑Shan Liu

Pages: 2055-2063 Published online on: 01 March 2019
Open Access

Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute lung injury in rats: Potential role of caveolin‑1 expression upregulation

Xiaojing Wu, Qian Kong, Zhongyuan Xia, Liying Zhan, Weina Duan, Xuemin Song

Pages: 2064-2074 Published online on: 01 March 2019
Open Access

URG11 promotes proliferation and induced apoptosis of LNCaP cells

Chenmin Sun, Guangming Zhang, Shujie Cheng, Haining Qian, Dong Li, Min Liu

Pages: 2075-2085 Published online on: 05 March 2019
Open Access

Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway

Mingli Yin, Zhongyang Shen, Liu Yang, Weiping Zheng, Hongli Song

Pages: 2086-2102 Published online on: 04 March 2019
Open Access

Loss of Fam20c causes defects in the acinar and duct structure of salivary glands in mice

Nan Miao, Yuanbo Zhan, Yingying Xu, Haoze Yuan, Chunlin Qin, Feng Lin, Xiaohua Xie, Sen Mu, Mengtong Yuan, Haibin Mu, Shouli Guo, Ying Li, Bin Zhang

Pages: 2103-2117 Published online on: 06 March 2019
Open Access

LC‑MS/MS proteomic analysis revealed novel associations of 37 proteins with T2DM and notable upregulation of immunoglobulins

Rabab Asghar Abdulwahab, Ayodele Alaiya, Zakia Shinwari, Abdul Ameer A. Allaith, Hayder A. Giha

Pages: 2118-2132 Published online on: 08 March 2019
Open Access

Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway

Min Wang, Ying Liu, Rui‑Le Pan, Rui‑Ying Wang, Shi‑Lan Ding, Wan‑Rui Dong, Gui‑Bo Sun, Jing‑Xue Ye, Xiao‑Bo Sun

Pages: 2133-2143 Published online on: 12 March 2019
Open Access

Neuroprotective effects of Scrophularia buergeriana extract against glutamate-induced toxicity in SH-SY5Y cells

Hae Jin Lee, Demetrios A. Spandidos, Aristidis Tsatsakis, Denisa Margina, Boris N. Izotov, Seung Hwan Yang

Pages: 2144-2152 Published online on: 19 March 2019
Open Access

Neuroinflammation and adult hippocampal neurogenesis in neuropathic pain and alkyl glycerol ethers treatment in aged mice

Anna Tyrtyshnaia, Igor Manzhulo, Yulia Kipryushina, Ekaterina Ermolenko

Pages: 2153-2163 Published online on: 21 March 2019
Open Access

Involvement of PLAGL1/ZAC1 in hypocretin/orexin transcription

Susumu Tanaka, Yoshiko Honda, Shizuka Takaku, Taro Koike, Souichi Oe, Yukie Hirahara, Takashi Yoshida, Nae Takizawa, Yasuharu Takamori, Kiyoshi Kurokawa, Tohru Kodama, Hisao Yamada

Pages: 2164-2176 Published online on: 20 March 2019

4'‑O‑Methylalpinumisoflavone inhibits the activation of onocytes/macrophages to an immunostimulatory phenotype induced by 27‑hydroxycholesterol

Jeonga Lee, Bo Young Kim, Yonghae Son, Do Hoang Giang, Dongho Lee, Seong‑Kug Eo, Koanhoi Kim

Pages: 2177-2186 Published online on: 18 March 2019

Molecular interplay between microRNA-130a and PTEN in palmitic acid-mediated impaired function of endothelial progenitor cells: Effects of metformin

Xuemei Gu, Xiao‑Qian Wang, Min‑Jie Lin, Haili Liang, Shi‑Yan Fan, Luyin Wang, Xiaoqing Yan, Wenyue Liu, Fei‑Xia Shen

Pages: 2187-2198 Published online on: 20 March 2019

Dimethylglycine sodium salt protects against oxidative damage and mitochondrial dysfunction in the small intestines of mice

Kaiwen Bai, Luyi Jiang, Shanli Zhu, Chengcheng Feng, Yongwei Zhao, Lili Zhang, Tian Wang

Pages: 2199-2211 Published online on: 11 February 2019

Single nucleotide polymorphism rs3746444 in miR‑499a affects susceptibility to non‑small cell lung carcinoma by regulating the expression of CD200

Nan Ge, Chunxia Mao, Qingbo Yang, Bin Han, Yongjie Wang, Linhao Xu, Xiuzhi Yang, Wenjie Jiao, Chuan Li

Pages: 2221-2229 Published online on: 05 March 2019

Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong‑Hee Kim, Bang‑Jin Kim, Seok‑Man Kim, Sun‑Uk Kim, Buom‑Yong Ryu

Pages: 2230-2240 Published online on: 13 March 2019

Peimine suppresses interleukin‑1β‑induced inflammation via MAPK downregulation in chondrocytes

Kun Chen, Zheng‑Tao Lv, Chen‑He Zhou, Shuang Liang, Wen Huang, Zheng‑Gang Wang, Wen‑Tao Zhu, Yu‑Ting Wang, Xing‑Zhi Jing, Hui Lin, Feng‑Jing Guo, Peng Cheng, An‑Min Chen

Pages: 2241-2251 Published online on: 21 March 2019

Ursolic acid downregulates thymic stromal lymphopoietin through the blockade of intracellular calcium/caspase‑1/NF‑κB signaling cascade in HMC‑1 cells

Phil‑Dong Moon, Na‑Ra Han, Jin Soo Lee, Hyung‑Min Kim, Hyun‑Ja Jeong

Pages: 2252-2258 Published online on: 22 March 2019
Open Access

[Corrigendum] Antiproliferative effects of imatinib mesylate on ZR‑75‑1 and MDA‑MB‑231 cell lines via PDGFR‑β, PDGF‑BB, c‑Kit and SCF expression

Ali Kadivar, Mohamed Ibrahim Noordin, Arya Aditya, Behnam Kamalidehghan, Ehsan Taghizadeh Davoudi, Reihaneh Sedghi, Hamid Akbari Javar

Pages: 2259-2259 Published online on: 04 March 2019
Open Access

[Corrigendum] Nkd2 promotes the differentiation of dental follicle stem/progenitor cells into osteoblasts

Chanchan Chen, Jianying Zhang, Junqi Ling, Yu Du, Yuluan Hou

Pages: 2260-2260 Published online on: 12 February 2019
Open Access

[Corrigendum] A 44‑gene set constructed for predicting the prognosis of clear cell renal cell carcinoma

Yonggang Wang, Yao Wang, Feng Liu

Pages: 2261-2261 Published online on: 19 March 2019
Journal Cover

May 2019
Volume 43 Issue 5

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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