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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2005 Volume 15 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Neuropeptide-Y and Y-receptors in the autocrine-paracrine regulation of adrenal gland under physiological and pathophysiological conditions (Review)

Raffaella Spinazzi, Paola G. Andreis, Gastone G. Nussdorfer
Pages: 3-13
Published online on: 01 January 2005

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Article

Angiogenesis in hereditary hemorrhagic telangiectasia: VEGF165 plasma concentration in correlation to the VEGF expression and microvessel density

Haneen Sadick, Ramin Naim, Ulrich Gössler, Karl Hörmann, Frank Riedel
Pages: 15-19
Published online on: 01 January 2005

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Article

Interferon-α gene therapy prevents aflatoxin and carbon tetrachloride promoted hepatic carcinogenesis in rats

Talaat Abdel Aziz, Mohammed Abdel Aziz, Hanan Hassan Fouad, Laila Ahmed Rashed, Hosny Salama, Samira Abd-Alla, Mosaad Attia Abdel Wehab, Tauseef Ahmed
Pages: 21-26
Published online on: 01 January 2005

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Article

Distinct expression patterns of α1 (IV) and α5 (IV) collagen chains in cylindroma and malignant cylindroma

Pascale Quatresooz, Gérald E. Piérard
Pages: 27-31
Published online on: 01 January 2005

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Article

RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells

Javier A. Menendez, Ruth Lupu
Pages: 33-40
Published online on: 01 January 2005

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Article

Expression of apoptosis-related proteins in advanced uterine cervical cancer after balloon-occluded arterial infusion chemotherapy as an indicator of the efficiency of this therapy

Eri Okamoto, Toshiyuki Sumi, Fumiko Misugi, Hiroyuki Nobeyama, Kanae Hattori, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Ken-Ichi Honda, Osamu Ishiko
Pages: 41-47
Published online on: 01 January 2005

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Article

Expression of thrombospondin-1 in prostate-derived cell lines

Manuela Bastian, Michael Steiner, Peter Schuff-Werner
Pages: 49-56
Published online on: 01 January 2005

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Article

Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque

Fei Chen, Per Eriksson, Göran K. Hansson, Istvan Herzfeld, Magareta Klein, Lars-Olof Hansson, Guro Valen
Pages: 57-65
Published online on: 01 January 2005

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Article

Hepatocyte growth factor/scatter factor induces VEGF in human external auditory canal cholesteatoma cell culture

Ramin Naim, Haneen Sadick, Christiane Bayerl, Frank Riedel, Carsten Schafer, Gregor Bran, Karl Hormann
Pages: 67-71
Published online on: 01 January 2005

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Article

The kinase domain of death-associated protein kinase is inhibitory for tubulointerstitial fibrosis in chronic obstructive nephropathy

Kazunori Yukawa, Masanori Kishino, Katsuaki Hoshino, Nobuyuki Shirasawa, Akihiko Kimura, Yuji Tsubota, Kyoko Owada-Makabe, Tao Bai, Tetsuji Tanaka, Takashi Ueyama, Masakazu Ichinose, Kiyoshi Takeda, Shizuo Akira, Masanobu Maeda
Pages: 73-78
Published online on: 01 January 2005

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Article

Interleukin-1β and tumor necrosis factor-α upregulate interleukin-23 subunit p19 gene expression in human colonic subepithelial myofibroblasts

Zhuobin Zhang, Akira Andoh, Hirofumi Yasui, Osamu Inatomi, Kazunori Hata, Tomoyuki Tsujikawa, Katsuyuki Kitoh, Atsushi Takayanagi, Nobuyoshi Shimizu, Yoshihide Fujiyama
Pages: 79-83
Published online on: 01 January 2005

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Article

The profile of hMLH1 methylation and microsatellite instability in colorectal and non-small cell lung cancer

Toshiyuki Okuda, Kazuyuki Kawakami, Kaname Ishiguro, Makoto Oda, Kenji Omura, Go Watanabe
Pages: 85-90
Published online on: 01 January 2005

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Article

Role of β2-chimaerin in the behaviour of murine mammary carcinoma cells in response to extracellular matrix components

Pablo Lorenzano Menna, Leticia Y. Peche, Daniel F. Alonso, Daniel E. Gomez
Pages: 91-95
Published online on: 01 January 2005

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Article

A novel regucalcin gene promoter region-related protein: Comparison of nucleotide and amino acid sequences in vertebrate species

Natsumi Sawada, Masayoshi Yamaguchi
Pages: 97-104
Published online on: 01 January 2005

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Article

Quantitative and qualitative alterations of intestinal mucins in BioBreeding rats

Philippe Courtois, Cedric Jurysta, Abdullah Sener, Fraser W. Scott, Willy J. Malaisse
Pages: 105-108
Published online on: 01 January 2005

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Article

The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex

Mitsuo Kodama, Toshiko Kodama
Pages: 109-116
Published online on: 01 January 2005

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Article

Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes

Alan J. Stewart, Joy Mukherjee, Scott J. Roberts, Douglas Lester, Colin Farquharson
Pages: 117-121
Published online on: 01 January 2005

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Article

Computationally analyzing the possible biological function of YJL103C - an ORF potentially involved in the regulation of energy process in yeast

Youping Deng, Tianyuan He, Yinong Wu, Phaneendra Vanka, George Yang, Yenchen Huang, Hongren Yao, Susan J. Brown
Pages: 123-127
Published online on: 01 January 2005

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Review

Occult and obscure bleeding, iron deficiency anemia and other gastrointestinal stories (Review)

Massimo Marignani, Stefano Angeletti, Luca Filippi, Roberta Danieli, Orazio Schillaci
Pages: 129-135
Published online on: 01 January 2005

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Article

Tumor associated antigen recognition by autologous serum in patients with breast cancer

Feng Qian, Kunle Odunsi, Lawrence M. Blatt, Matthew J. Scanlan, Manish Mannan, Nisha Shah, John Montgomery, Fadi Haddad, Milton Taylor
Pages: 137-144
Published online on: 01 January 2005

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Article

VEGF-subtype specific protection of SCC and HUVECs from radiation induced cell death

Jürgen Brieger, Petra Schroeder, Jan Gosepath, Wolf J. Mann
Pages: 145-151
Published online on: 01 January 2005

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Article

Involvement of intercellular adhesion molecule-1 and β1 integrin in the internalization process to human endothelial cells of group B Streptococcus clinical isolates

Viviane O.F. Lione, Gabriela S. Santos, Raphael Hirata Júnior, Ana Luiza Mattos-Guaraldi, Prescilla E. Nagao
Pages: 153-157
Published online on: 01 January 2005

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Article

Multifocal oscillatory potentials in CSNB1 and CSNB2 type congenital stationary night blindness

Andreas Schuster, Carsten M. Pusch, Daphine Gamer, Eckart Apfelstedt-Sylla, Eberhart Zrenner, Anne Kurtenbach
Pages: 159-167
Published online on: 01 January 2005

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Article

The histone deacetylase inhibitor suberoylanilide hydroxamic acid down-regulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines

Yaoxian Xu, Susanne Voelter-Mahlknecht, Ulrich Mahlknecht
Pages: 169-172
Published online on: 01 January 2005

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Article

Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects

Kaname Nakatani, Katsura Noma, Junji Nishioka, Yasunari Kasai, Kohei Morioka, Akira Katsuki, Yasuko Hori, Yutaka Yano, Yasuhiro Sumida, Hideo Wada, Tsutomu Nobori
Pages: 173-177
Published online on: 01 January 2005

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Published online on: 01 December 2025

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[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

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Published online on: 01 December 2025

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