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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2007 Volume 30 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

PLAG1, the prototype of the PLAG gene family: Versatility in tumour development (Review)

Frederik Van Dyck, Jeroen Declercq, Caroline V. Braem, Wim J.M. Van de Ven
Pages: 765-774
Published online on: 01 April 2007

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Article

Overexpression of the opioid growth factor receptor potentiates growth inhibition in human pancreatic cancer cells

Ian S. Zagon, Michael F. Verderame, Jody Hankins, Patricia J. McLaughlin
Pages: 775-783
Published online on: 01 April 2007

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Article

Cyclooxygenase-2 uses the protein kinase C/ interleukin-8/urokinase-type plasminogen activator pathway to increase the invasiveness of breast cancer cells

Ann-Marie Simeone, Rene Nieves-Alicea, Vanity C. McMurtry, Stephen Colella, Ralfe Krahe, Ana M. Tari
Pages: 785-792
Published online on: 01 April 2007

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Article

Silencing hypoxia-inducible factor-1α inhibits cell migration and invasion under hypoxic environment in malignant gliomas

Satoshi Fujiwara, Kou Nakagawa, Hironobu Harada, Shigeyuki Nagato, Koji Furukawa, Mikio Teraoka, Toshimoto Seno, Keizo Oka, Shinji Iwata, Takanori Ohnishi
Pages: 793-802
Published online on: 01 April 2007

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Article

TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma

Jiro Nakagawa, Masanao Saio, Noriyuki Tamakawa, Tatsuhiko Suwa, Alan B. Frey, Kenichi Nonaka, Naoki Umemura, Hisashi Imai, Guan-Feng Ouyang, Naoyuki Ohe, Hirohito Yano, Sinichi Yoshimura, Toru Iwama, Tsuyoshi Takami
Pages: 803-811
Published online on: 01 April 2007

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Review

Human papillomavirus: Its identikit and controversial role in oral oncogenesis, premalignant and malignant lesions (Review)

Giuseppina Campisi, Vera Panzarella, Michele Giuliani, Carlo Lajolo, Olga Di Fede, Silvia Falaschini, Chiara Di Liberto, Crispian Scully, Lorenzo Lo Muzio
Pages: 813-823
Published online on: 01 April 2007

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Article

Expression of interleukin-11 (IL-11) and IL-11 receptor α in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells

Toshiyuki Nakayama, Ayumi Yoshizaki, Seiya Izumida, Tomoyuki Suehiro, Shiro Miura, Takashi Uemura, Yuichi Yakata, Kazuko Shichijo, Shunichi Yamashita, Ichiro Sekin
Pages: 825-833
Published online on: 01 April 2007

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Article

Identification of DR9-restricted XAGE antigen on lung adenocarcinoma recognized by autologous CD4 T-cells

Michihide Shimono, Akiko Uenaka, Yuji Noguchi, Shuichiro Sato, Hideo Okumura, Kazuhiko Nakagawa, Katsuyuki Kiura, Mitsune Tanimoto, Eiichi Nakayama
Pages: 835-840
Published online on: 01 April 2007

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Article

Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase

H. Dorota Halicka, Barbara Ardelt, Kuslima Shogen, Zbigniew Darzynkiewicz
Pages: 841-847
Published online on: 01 April 2007

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Article

Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry

Kuniko Mikuriya, Yasuhiro Kuramitsu, Shomei Ryozawa, Masanori Fujimoto, Sayaka Mori, Masaaki Oka, Kimikazu Hamano, Kiwamu Okita, Isao Sakaida, Kazuyuki Nakamura
Pages: 849-855
Published online on: 01 April 2007

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Article

An automated nanoliter dispenser for staining individual biopsies in tissue microarrays

Jared Slobodan, Dylan Gunn, Jason Thompson, Kurtis Guggenheimer, Keddie Brown, Mark Homenuke, Roy Belak, Diponkar Banerjee, David Broemeling, Andre Marziali
Pages: 857-863
Published online on: 01 April 2007

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Article

Ephrin-A1 is a negative regulator in glioma through down-reguation of EphA2 and FAK

Dong-Ping Liu, Yan Wang, H. Phillip Koeffler, Dong Xie
Pages: 865-871
Published online on: 01 April 2007

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Article

The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography

Ken-Ichiro Matsumoto, Lawrence Szajek, Murali C. Krishna, John A. Cook, Jurgen Seidel, Kelly Grimes, Joann Carson, Anastasia L. Sowers, Sean English, Michael V. Green, Stephen L. Bacharach, William C. Eckelman, James B. Mitchell
Pages: 873-881
Published online on: 01 April 2007

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Article

Insulin-like growth factor binding protein-4 gene therapy increases apoptosis by altering Bcl-2 and Bax proteins and decreases angiogenesis in colorectal cancer

Rajaraman Durai, Shi Yu Yang, Kevin M. Sales, Alexander M. Seifalian, Geoffrey Goldspink, Marc C. Winslet
Pages: 883-888
Published online on: 01 April 2007

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Article

Novel natural immunogenic peptides from Numb1 and Notch1 proteins for CD8+ cells in ovarian ascites

Satoshi Ishiyama, Satoko Matsueda, Lovell A. Jones, Clay Efferson, Joseph Celestino, Rosemarie Schmandt, Constantin G. Ioannides, Naotake Tsuda, David Z. Chang
Pages: 889-898
Published online on: 01 April 2007

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Article

Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix

Sonali P. Barwe, Raymond S. Maul, Jason J. Christiansen, Gopalakrishnapillai Anilkumar, Carlton R. Cooper, Donald B. Kohn, Ayyappan K. Rajasekaran
Pages: 899-904
Published online on: 01 April 2007

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Article

Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer

Sharmila Shankar, Rakesh K. Srivastava
Pages: 905-918
Published online on: 01 April 2007

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Article

Overexpression of XIAP expression in renal cell carcinoma predicts a worse prognosis

Yoichi Mizutani, Hiroyuki Nakanishi, Yong Nan Li, Hiroki Matsubara, Kosuke Yamamoto, Nodoka Sato, Takumi Shiraishi, Terukazu Nakamura, Kazuya Mikami, Koji Okihara, Natsuki Takaha, Osamu Ukimura, Akihiro Kawauchi, Norio Nonomura, Benjamin Bonavida, Tsuneharu Miki
Pages: 919-925
Published online on: 01 April 2007

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Article

Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neck

Alexander Sauter, Charlotte Kloft, Silke Gronau, Felix Bogeschdorfer, Thomas Erhardt, Wolfram Golze, Carsten Schroen, Alexander Staab, Herbert Riechelmann, Karl Hoermann
Pages: 927-935
Published online on: 01 April 2007

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Article

Blockade of the vascular endothelial growth factor-receptor 2 pathway inhibits the growth of human renal cell carcinoma, RBM1-IT4, in the kidney but not in the bone of nude mice

Takashi Karashima, Keji Inoue, Satoshi Fukata, Tatsuo Iiyama, Atsushi Kurabayashi, Chiaki Kawada, Taro Shuin
Pages: 937-945
Published online on: 01 April 2007

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Article

Dexamethasone as a chemosensitizer for breast cancer chemotherapy: Potentiation of the antitumor activity of adriamycin, modulation of cytokine expression, and pharmacokinetics

Hui Wang, Ying Wang, Elizabeth R. Rayburn, Donald L. Hill, John J. Rinehart, Ruiwen Zhang
Pages: 947-953
Published online on: 01 April 2007

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Article

A new comprehensive gene expression panel to study tumor micrometastasis in patients with high-risk breast cancer

P. F. Ferrucci, C. Rabascio, F. Gigli, C. Corsini, G. Giordano, F. Bertolini, G. Martinelli
Pages: 955-962
Published online on: 01 April 2007

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Article

Combined effect of green tea and Ganoderma lucidum on invasive behavior of breast cancer cells

Anita Thyagarajan, Jiashi Zhu, Daniel Sliva
Pages: 963-969
Published online on: 01 April 2007

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Article

Inhibition of the MAP kinase activity suppresses estrogen-induced breast tumor growth both in vitro and in vivo

Kaladhar B. Reddy, Selina Glaros
Pages: 971-975
Published online on: 01 April 2007

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Article

Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression

Hidenobu Kamohara, Michio Ogawa, Takatoshi Ishiko, Kiyoshi Sakamoto, Hideo Baba
Pages: 977-983
Published online on: 01 April 2007

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Article

MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells

M. Burg-Roderfeld, M. Roderfeld, S. Wagner, C. Henkel, J. Grötzinger, E. Roeb
Pages: 985-992
Published online on: 01 April 2007

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Article

Arsenic trioxide induces p53-dependent apoptotic signals in myeloma cells with SiRNA-silenced p53: MAP kinase pathway is preferentially activated in cells expressing inactivated p53

Fatih Kircelli, Cagla Akay, Yair Gazitt
Pages: 993-1001
Published online on: 01 April 2007

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Article

Differential modulation of nuclear texture, histone acetylation, and MDR1 gene expression in human drug-sensitive and -resistant OV1 cell lines

Sonia Yatouji, Victoria El-Khoury, Chantal Trentesaux, Aurelie Trussardi-Regnier, Rym Benabid, Franck Bontems, Jean Dufer
Pages: 1003-1009
Published online on: 01 April 2007

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Article

Immunization with MHC class I-negative but not -positive HPV16-associated tumour cells inhibits growth of MHC class I-negative tumours

Milan Reinis, Jana Símová, Marie Indrová, Jana Bieblová, Hana Pribylová, Simona Moravcová, Tána Jandlová, Jan Bubeník
Pages: 1011-1017
Published online on: 01 April 2007

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Article

Alterations of EGFR/HER, angiogenesis and apoptosis pathways after therapy with antagonists of growth hormone releasing hormone and bombesin in non-small cell lung cancer

Celia A. Kanashiro, Andrew V. Schally, Marta Zarandi, Brian D. Hammann, Jozsef L. Varga
Pages: 1019-1028
Published online on: 01 April 2007

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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