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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2007 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

In vitro combination characterization of the new anticancer plant drug β-elemene with taxanes against human lung carcinoma

Jinshun Zhao, Qingdi Q. Li, Baobo Zou, Gangduo Wang, Xiping Li, Jee Eun Kim, Christopher F. Cuff, Lan Huang, Eddie Reed, Kevin Gardner
Pages: 241-252
Published online on: 01 August 2007

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Article

Methodological approach to study the genomic profile of the human breast

Gabriela A. Balogh, Rebecca Heulings, Daniel Mailo, Richard Wang, Yue-Sheng Li, Randy Hardy, Jose Russo
Pages: 253-260
Published online on: 01 August 2007

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Article

3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition

Shingo Ito, Nobuko Koshikawa, Shigenobu Mochizuki, Keizo Takenaga
Pages: 261-268
Published online on: 01 August 2007

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Article

Loss of E-cadherin in the vicinity of necrosis in colorectal carcinomas: Association with NFκB expression

Nektaria Simiantonaki, Ursula Kurzik-Dumke, Georgia Karyofylli, Caren Jayasinghe, Charles James Kirkpatrick
Pages: 269-275
Published online on: 01 August 2007

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Article

Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells

Hiroaki Kajiyama, Kiyosumi Shibata, Mikio Terauchi, Mamoru Yamashita, Kazuhiko Ino, Akihiro Nawa, Fumitaka Kikkawa
Pages: 277-283
Published online on: 01 August 2007

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Article

Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells

Toyotaka Iguchi, Yoshitaka Miyakawa, Kaori Saito, Chika Nakabayashi, Makoto Nakanishi, Hideyuki Saya, Yasuo Ikeda, Masahiro Kizaki
Pages: 285-291
Published online on: 01 August 2007

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Article

Identification of a novel gene HEPT3 that is overexpressed in human hepatocellular carcinoma and may function through its noncoding RNA

Mei Chung Moh, Lay Hoon Lee, Xiaodong Yang, Shali Shen
Pages: 293-301
Published online on: 01 August 2007

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Article

Immune-surveillance and programmed cell death-related genes are significantly overexpressed in the normal breast epithelium of postmenopausal parous women

G. A. Balogh, I. H. Russo, C. Spittle, R. Heulings, J. Russo
Pages: 303-312
Published online on: 01 August 2007

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Article

Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy

Hitoshi Zembutsu, Masamitsu Yanada, Asahi Hishida, Toyomasa Katagiri, Takashi Tsuruo, Isamu Sugiura, Jin Takeuchi, Noriko Usui, Tomoki Naoe, Yusuke Nakamura, Ryuzo Ohno
Pages: 313-322
Published online on: 01 August 2007

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Article

Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells

Mutsumi Ogawa, Seiji Nakai, Akihiro Deguchi, Takako Nonomura, Tsutomu Masaki, Naohito Uchida, Hitoshi Yoshiji, Shigeki Kuriyama
Pages: 323-331
Published online on: 01 August 2007

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Article

Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer

Yoshimasa Kosaka, Koshi Mimori, Fumiaki Tanaka, Hiroshi Inoue, Masahiko Watanabe, Masaki Mori
Pages: 333-338
Published online on: 01 August 2007

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Article

Immortalization and characterization of pleomorphic adenoma cells by transfection with the hTERT gene

Masae Kitagawa, Ikuko Ogawa, Kaori Shima, Sadamitsu Hashimoto, Yasusei Kudo, Mutsumi Miyauchi, Hidetoshi Tahara, Masaki Shimono, Takashi Takata
Pages: 339-344
Published online on: 01 August 2007

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Article

Interference between p53 and cdc25C in cell cycle regulation

Sandra L. Ruppenthal, Andreas Noll, Claudia Götz, Mathias Montenarh
Pages: 345-362
Published online on: 01 August 2007

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Article

Auristatin PYE, a novel synthetic derivative of dolastatin 10, is highly effective in human colon tumour models

Steven D. Shnyder, Patricia A. Cooper, Nicola J. Millington, G. Robert Pettit, Michael C. Bibby
Pages: 353-360
Published online on: 01 August 2007

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Article

Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner

Peng Zhao, Cunzu Wang, Zhen Fu, Yongping You, Yunxiang Cheng, Xiaoming Lu, Ailin Lu, Ning Liu, Peiyu Pu, Chunsheng Kang, Leif G. Salford, Xiaolong Fan
Pages: 361-368
Published online on: 01 August 2007

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Article

Scintimammography with dedicated breast camera in unifocal and multifocal/multicentric primary breast cancer detection: A comparative study with SPECT

Angela Spanu, Pierina Cottu, Alessandra Manca, Francesca Chessa, Daniela Sanna, Giuseppe Madeddu
Pages: 369-377
Published online on: 01 August 2007

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Article

Epstein-Barr virus-based vector improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy

Tsuyoshi Izumo, Akira Ohtsuru, Yoshiharu Tokunaga, Hiroyuki Namba, Yasufumi Kaneda, Izumi Nagata, Shunichi Yamashita
Pages: 379-387
Published online on: 01 August 2007

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Article

Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-κB in human osteoblastic osteosarcoma MG63 cells

Hiroaki Tanaka, Kaya Yoshida, Hirohiko Okamura, Hiroyuki Morimoto, Toshihiko Nagata, Tatsuji Haneji
Pages: 389-396
Published online on: 01 August 2007

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Article

RARα is a regulatory factor for Am-80-induced cell growth inhibition of hematologic malignant cells

Shiro Jimi, Kota Mashima, Taichi Matsumoto, Shuji Hara, Junji Suzumiya, Kazuo Tamura
Pages: 397-404
Published online on: 01 August 2007

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Article

Hedgehog-independent overexpression of transforming growth factor-β1 in rhabdomyosarcoma of Patched1 mutant mice

Melanie Eichenmüller, Regine Bauer, Dietrich Von Schweinitz, Heidi Hahn, Roland Kappler
Pages: 405-412
Published online on: 01 August 2007

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Article

DPD is a molecular determinant of capecitabine efficacy in colorectal cancer

Daniel Vallböhmer, Dong Yun Yang, Hidekazu Kuramochi, D. Shimizu, Kathleen D. Danenberg, Jan Lindebjerg, Jens Nederby Nielsen, Anders Jakobsen, Peter V. Danenberg
Pages: 413-418
Published online on: 01 August 2007

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Article

Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes

Alexander Kaszubiak, Per Sonne Holm, Hermann Lage
Pages: 419-430
Published online on: 01 August 2007

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Article

Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma

Rongcai Jiang, Woonyoung Choi, Asad Khan, Kenneth Hess, Eugene W. Gerner, Robert A. Casero, W. K.Alfred Yung, Stanley R. Hamilton, Wei Zhang
Pages: 431-440
Published online on: 01 August 2007

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Article

Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway

Veronica C. Estrella, Astrid M.. Eder, Shuying Liu, Terri B. Pustilnik, Fazal H. Tabassam, Francois X. Claret, Gary E. Gallick, Gordon B. Mills, Jon R. Wiener
Pages: 441-449
Published online on: 01 August 2007

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Article

In vitro c-met inhibition by antisense RNA and plasmid-based RNAi down-modulates migration and invasion of hepatocellular carcinoma cells

Alessandro Salvi, Bruna Arici, Nazario Portolani, Stefano Maria Giulini, Giuseppina De Petro, Sergio Barlati
Pages: 451-460
Published online on: 01 August 2007

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Article

Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer

Masuko Katoh, Masaru Katoh
Pages: 461-466
Published online on: 01 August 2007

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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