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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2007 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

In vitro combination characterization of the new anticancer plant drug β-elemene with taxanes against human lung carcinoma

Jinshun Zhao, Qingdi Q. Li, Baobo Zou, Gangduo Wang, Xiping Li, Jee Eun Kim, Christopher F. Cuff, Lan Huang, Eddie Reed, Kevin Gardner
Pages: 241-252
Published online on: 01 August 2007

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Article

Methodological approach to study the genomic profile of the human breast

Gabriela A. Balogh, Rebecca Heulings, Daniel Mailo, Richard Wang, Yue-Sheng Li, Randy Hardy, Jose Russo
Pages: 253-260
Published online on: 01 August 2007

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Article

3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition

Shingo Ito, Nobuko Koshikawa, Shigenobu Mochizuki, Keizo Takenaga
Pages: 261-268
Published online on: 01 August 2007

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Article

Loss of E-cadherin in the vicinity of necrosis in colorectal carcinomas: Association with NFκB expression

Nektaria Simiantonaki, Ursula Kurzik-Dumke, Georgia Karyofylli, Caren Jayasinghe, Charles James Kirkpatrick
Pages: 269-275
Published online on: 01 August 2007

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Article

Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells

Hiroaki Kajiyama, Kiyosumi Shibata, Mikio Terauchi, Mamoru Yamashita, Kazuhiko Ino, Akihiro Nawa, Fumitaka Kikkawa
Pages: 277-283
Published online on: 01 August 2007

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Article

Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells

Toyotaka Iguchi, Yoshitaka Miyakawa, Kaori Saito, Chika Nakabayashi, Makoto Nakanishi, Hideyuki Saya, Yasuo Ikeda, Masahiro Kizaki
Pages: 285-291
Published online on: 01 August 2007

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Article

Identification of a novel gene HEPT3 that is overexpressed in human hepatocellular carcinoma and may function through its noncoding RNA

Mei Chung Moh, Lay Hoon Lee, Xiaodong Yang, Shali Shen
Pages: 293-301
Published online on: 01 August 2007

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Article

Immune-surveillance and programmed cell death-related genes are significantly overexpressed in the normal breast epithelium of postmenopausal parous women

G. A. Balogh, I. H. Russo, C. Spittle, R. Heulings, J. Russo
Pages: 303-312
Published online on: 01 August 2007

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Article

Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy

Hitoshi Zembutsu, Masamitsu Yanada, Asahi Hishida, Toyomasa Katagiri, Takashi Tsuruo, Isamu Sugiura, Jin Takeuchi, Noriko Usui, Tomoki Naoe, Yusuke Nakamura, Ryuzo Ohno
Pages: 313-322
Published online on: 01 August 2007

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Article

Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells

Mutsumi Ogawa, Seiji Nakai, Akihiro Deguchi, Takako Nonomura, Tsutomu Masaki, Naohito Uchida, Hitoshi Yoshiji, Shigeki Kuriyama
Pages: 323-331
Published online on: 01 August 2007

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Article

Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer

Yoshimasa Kosaka, Koshi Mimori, Fumiaki Tanaka, Hiroshi Inoue, Masahiko Watanabe, Masaki Mori
Pages: 333-338
Published online on: 01 August 2007

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Article

Immortalization and characterization of pleomorphic adenoma cells by transfection with the hTERT gene

Masae Kitagawa, Ikuko Ogawa, Kaori Shima, Sadamitsu Hashimoto, Yasusei Kudo, Mutsumi Miyauchi, Hidetoshi Tahara, Masaki Shimono, Takashi Takata
Pages: 339-344
Published online on: 01 August 2007

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Interference between p53 and cdc25C in cell cycle regulation

Sandra L. Ruppenthal, Andreas Noll, Claudia Götz, Mathias Montenarh
Pages: 345-362
Published online on: 01 August 2007

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Article

Auristatin PYE, a novel synthetic derivative of dolastatin 10, is highly effective in human colon tumour models

Steven D. Shnyder, Patricia A. Cooper, Nicola J. Millington, G. Robert Pettit, Michael C. Bibby
Pages: 353-360
Published online on: 01 August 2007

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Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner

Peng Zhao, Cunzu Wang, Zhen Fu, Yongping You, Yunxiang Cheng, Xiaoming Lu, Ailin Lu, Ning Liu, Peiyu Pu, Chunsheng Kang, Leif G. Salford, Xiaolong Fan
Pages: 361-368
Published online on: 01 August 2007

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Article

Scintimammography with dedicated breast camera in unifocal and multifocal/multicentric primary breast cancer detection: A comparative study with SPECT

Angela Spanu, Pierina Cottu, Alessandra Manca, Francesca Chessa, Daniela Sanna, Giuseppe Madeddu
Pages: 369-377
Published online on: 01 August 2007

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Epstein-Barr virus-based vector improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy

Tsuyoshi Izumo, Akira Ohtsuru, Yoshiharu Tokunaga, Hiroyuki Namba, Yasufumi Kaneda, Izumi Nagata, Shunichi Yamashita
Pages: 379-387
Published online on: 01 August 2007

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Article

Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-κB in human osteoblastic osteosarcoma MG63 cells

Hiroaki Tanaka, Kaya Yoshida, Hirohiko Okamura, Hiroyuki Morimoto, Toshihiko Nagata, Tatsuji Haneji
Pages: 389-396
Published online on: 01 August 2007

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Article

RARα is a regulatory factor for Am-80-induced cell growth inhibition of hematologic malignant cells

Shiro Jimi, Kota Mashima, Taichi Matsumoto, Shuji Hara, Junji Suzumiya, Kazuo Tamura
Pages: 397-404
Published online on: 01 August 2007

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Article

Hedgehog-independent overexpression of transforming growth factor-β1 in rhabdomyosarcoma of Patched1 mutant mice

Melanie Eichenmüller, Regine Bauer, Dietrich Von Schweinitz, Heidi Hahn, Roland Kappler
Pages: 405-412
Published online on: 01 August 2007

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Article

DPD is a molecular determinant of capecitabine efficacy in colorectal cancer

Daniel Vallböhmer, Dong Yun Yang, Hidekazu Kuramochi, D. Shimizu, Kathleen D. Danenberg, Jan Lindebjerg, Jens Nederby Nielsen, Anders Jakobsen, Peter V. Danenberg
Pages: 413-418
Published online on: 01 August 2007

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Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes

Alexander Kaszubiak, Per Sonne Holm, Hermann Lage
Pages: 419-430
Published online on: 01 August 2007

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Article

Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma

Rongcai Jiang, Woonyoung Choi, Asad Khan, Kenneth Hess, Eugene W. Gerner, Robert A. Casero, W. K.Alfred Yung, Stanley R. Hamilton, Wei Zhang
Pages: 431-440
Published online on: 01 August 2007

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Article

Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway

Veronica C. Estrella, Astrid M.. Eder, Shuying Liu, Terri B. Pustilnik, Fazal H. Tabassam, Francois X. Claret, Gary E. Gallick, Gordon B. Mills, Jon R. Wiener
Pages: 441-449
Published online on: 01 August 2007

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Article

In vitro c-met inhibition by antisense RNA and plasmid-based RNAi down-modulates migration and invasion of hepatocellular carcinoma cells

Alessandro Salvi, Bruna Arici, Nazario Portolani, Stefano Maria Giulini, Giuseppina De Petro, Sergio Barlati
Pages: 451-460
Published online on: 01 August 2007

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Article

Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer

Masuko Katoh, Masaru Katoh
Pages: 461-466
Published online on: 01 August 2007

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Resistance to covalent Bruton's tyrosine kinase inhibitors in diffuse large B‑cell lymphoma: Molecular mechanisms and therapeutic implications (Review)

Chuanyang Lu, Tingting Zhou, Wenxin Zhang, Lulu Wei, Qiuni Chen, Yuye Shi, Chunling Wang, Liang Yu
Article Number: 134
Published online on: 09 October 2026

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Comprehensive landscape and future perspectives of PIWI‑interacting RNAs in cancer (Review)

Xiaoqian Yu, Changlong Li, Tongtao Zhuang, Siqing Sun, Xiaoyun He, Zhenyu Ou, Nannan Li, Chunlin Ou
Article Number: 133
Published online on: 09 October 2026

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Nucleocytoplasmic transport in gynaecological cancer: From mechanisms to therapeutic potential (Review)

Ieva Norkaityte, Laura Marija Racyte, Egle Balciunaite, Aiste Avizaite, Egle Zalyte
Article Number: 132
Published online on: 08 October 2026

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cGAS‑STING pathway in digestive tract cancer: From molecular mechanisms to therapeutic applications (Review)

Tangna Chen, Jingyi Zhang, Jinghan Sun, Hongyan Zhang, Deqiang Huang, Haifeng Ye
Article Number: 131
Published online on: 07 October 2026

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Regulatory T cells in lung adenocarcinoma: Mechanisms of immune escape, prognostic significance and therapeutic opportunities (Review)

Lijuan Wang, Chenjin Ruan
Article Number: 130
Published online on: 06 October 2026

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Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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Journal Cover
December-2026 Volume 69 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Mitochondrial dysfunction in T‑cell exhaustion: Its contribution to the efficacy of cancer immunotherapy (Review)

Yanan Shao, Min Gao, Shuqing Mao, Haibo Li, Jian Cui
Article Number: 146
Published online on: 13 November 2026

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Article Open Access

PRMT1 blockade reverts resistance to KRAS (G12C) inhibition through modulating ferroptosis signalling

Xiaoshuang Fu, Ziqi Wang, Xiayao Yu, Haolin Song, Han Si, Yuchen Fei, Yuhui Li, Keying Zhang, Yuce Wei, Rongrong Gao, Renqing Mu, Ling Xie, Zhengbo Song
Article Number: 145
Published online on: 12 November 2026

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Review

CRISPR opens the door to targeted therapy against glioblastoma (Review)

Chunzhi Zhang, Yixin Zhang, Nachuan Song, Le Zhang, Yunying Zhao, Chi Yao
Article Number: 144
Published online on: 12 November 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of the p38 MAPK pathway sensitises human colon cancer cells to 5‑fluorouracil treatment

Shi Yu Yang, Anur Miah, Kevin M. Sales, Barry Fuller, Alexander M. Seifalian, Marc Winslet
Article Number: 143
Published online on: 11 November 2026

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Review Open Access

Metabolic‑epigenetic coupling via lysine lactylation drives cancer stemness and multidrug resistance (Review)

Ying Yang, Nan Zhang, Dan Wang, Dongmei Ye, Yun Zhang, Xiaoju Li
Article Number: 142
Published online on: 09 November 2026

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Correction Open Access

[Corrigendum] ETS‑1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer

Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang
Article Number: 141
Published online on: 02 November 2026

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Article Open Access

PLD2 fuels 5‑fluorouracil resistance in colorectal cancer: Hypoxic hijacking of autophagy unveils a novel therapeutic vulnerability

Kunli Du, Pengfei Wang, Xisheng Yang, Yanjun Lu, Yi Wang, Wenda Wang, Jianyong Zheng, Maoxi Liu
Article Number: 140
Published online on: 02 November 2026

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Review

Pyroptosis in cancer nanotherapy: Molecular mechanisms and advanced nanosystems (Review)

Wesam H. Abdulaal, Nada H. Aljarba, Bonglee Kim, Islam M. Saadeldin, Faris Q. Alenzi, Altaf A. Abdulkhaliq, Johra Khan, Anwar Borai, Jaakko Tuomilehto, E Lin, Amir Ajoolabady, Ahmed Al‑Qahtani, Jun Ren
Article Number: 139
Published online on: 30 October 2026

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Correction Open Access

[Corrigendum] Monoamine carboxylate transporters are involved in BI-1-associated cancer metastasis in HT1080 colon fibrosarcoma cells

Geum-Hwa Lee, Han-Jung Chae, Hyung-Ryong Kim
Article Number: 138
Published online on: 19 October 2026

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Article Open Access

Disporum cantoniense suppresses non‑small cell lung cancer through AMPK/mTOR/ULK1‑mediated autophagy‑dependent apoptosis

Chi Feng, Yujiao Ji, Renqiang Chen, Qiuxu Chen, Yiru Pan, Jianming Wu, Dalian Qin, Betty Yuen Kwan Law, Vincent Kam Wai Wong, Xiaogang Zhou, Jianxin Liu, Anguo Wu
Article Number: 137
Published online on: 15 October 2026

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Research progress of SPP1 in cancer regulation: Tumorigenesis, metastasis, tumor microenvironment, immunity and therapeutic targets (Review)

Yujun Xia, Dong Han, Song Tang, Huimin Yang, Rongjie Zhao, Beibei Cao, Peixi Zhu, Aiqin Shi, Huacheng Luo
Article Number: 136
Published online on: 14 October 2026

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Correction Open Access

[Corrigendum] Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER‑inhibitors is accompanied by increased sensitivity to STAT3 inhibition

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, David Mackintosh, Flavio Solca, Helmout Modjtahedi
Article Number: 135
Published online on: 09 October 2026

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