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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2009 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Colorectal cancer detection by measuring DNA from exfoliated colonocytes obtained by direct contact with rectal mucosa

Alexandre Loktionov, Tatiana Bandaletova, Andrew H. Llewelyn, Carine Dion, Hugo G.G. Lywood, Rupert C.G. Lywood, Tim A. Rockall, John F. Stebbing, Mary Broughton, Sue Caffarey, Christopher G. Marks
Pages: 301-311
Published online on: 01 February 2009

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Article

Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer

Yoko Tabuchi, Junji Matsuoka, Mehmet Gunduz, Takako Imada, Ryoko Ono, Mitsuya Ito, Takayuki Motoki, Tomoki Yamatsuji, Yasuhiro Shirakawa, Munenori Takaoka, Minoru Haisa, Noriaki Tanaka, Junichi Kurebayashi, V. Craig Jordan, Yoshio Naomoto
Pages: 313-319
Published online on: 01 February 2009

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Article

Soluble form of ephrinB2 inhibits xenograft growth of squamous cell carcinoma of the head and neck

Machiko Kimura, Yasumasa Kato, Daisuke Sano, Kyoko Fujita, Atsuko Sakakibara, Norio Kondo, Yasukazu Mikami, Mamoru Tsukuda
Pages: 321-327
Published online on: 01 February 2009

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Article

Autocrine loop for IGF-I receptor signaling in SLUG-mediated epithelial-mesenchymal transition

Ramadoss Sivakumar, Hironori Koga, Karuppaiyah Selvendiran, Michiko Maeyama, Takato Ueno, Michio Sata
Pages: 329-338
Published online on: 01 February 2009

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Article

Adiponectin inhibits colorectal cancer cell growth through the AMPK/mTOR pathway

Michiko Sugiyama, Hirokazu Takahashi, Kunihiro Hosono, Hiroki Endo, Shingo Kato, Kyoko Yoneda, Yuichi Nozaki, Koji Fujita, Masato Yoneda, Koichiro Wada, Hitoshi Nakagama, Atsushi Nakajima
Pages: 339-344
Published online on: 01 February 2009

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Article

Expression of hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) in ovarian cancer

Keiichiro Nakamura, Fernando Abarzua, Junichi Kodama, Atsushi Hongo, Yasutomo Nasu, Hiromi Kumon, Yuji Hiramatsu
Pages: 345-353
Published online on: 01 February 2009

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Article

Keratinocyte growth factor induces vascular endothelial growth factor-A expression in colorectal cancer cells

Kosuke Narita, Takenori Fujii, Toshiyuki Ishiwata, Tetsushi Yamamoto, Yoko Kawamoto, Kiyoko Kawahara, Nando Nakazawa, Zenya Naito
Pages: 355-360
Published online on: 01 February 2009

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Article

Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling

Hitoshi Zembutsu, Yasuyo Suzuki, Aya Sasaki, Tatsuhiko Tsunoda, Minoru Okazaki, Masataka Yoshimoto, Tadashi Hasegawa, Koichi Hirata, Yusuke Nakamura
Pages: 361-370
Published online on: 01 February 2009

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Article

Mineral fiber-mediated activation of phosphoinositide-specific phospholipase c in human bronchoalveolar carcinoma-derived alveolar epithelial A549 cells

Carla Loreto, Maria Luisa Carnazza, Venera Cardile, Massimo Libra, Laura Lombardo, Grazia Malaponte, Giuseppina Martinez, Giuseppe Musumeci, Veronica Papa, Lucio Cocco
Pages: 371-376
Published online on: 01 February 2009

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Article Open Access

Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes

Ayguen Sahin, Chantal Vercamer, Annette Kaminski, Tanja Fuchs, Alexandra Florin, Jens Claus Hahne, Virginie Mattot, Albin Pourtier-Manzanedo, Torsten Pietsch, Véronique Fafeur, Nicolas Wernert
Pages: 377-389
Published online on: 01 February 2009

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Article

Epigenetic regulation of hTERT promoter in hepatocellular carcinomas

Dimitrios Iliopoulos, Maria Satra, Alexandra Drakaki, George A. Poultsides, Aspasia Tsezou
Pages: 391-399
Published online on: 01 February 2009

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Article

Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma

Nibal Zaghloul, Sonia L. Hernandez, Jae-O Bae, Jianzhong Huang, Jason C. Fisher, Alice Lee, Angela Kadenhe-Chiweshe, Jessica J. Kandel, Darrell J. Yamashiro
Pages: 401-407
Published online on: 01 February 2009

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Article

Mutation of PIK3CA: Possible risk factor for cervical carcinogenesis in older women

Baoxia Cui, Biying Zheng, Xi Zhang, Ulf Stendahl, Sonia Andersson, Keng-Ling Wallin
Pages: 409-416
Published online on: 01 February 2009

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Article

Delineation of yet unknown cryptic subtelomere aberrations in 50% of acute myeloid leukemia with normal GTG-banding karyotype

Madeleine Gross, Hasmik Mkrtchyan, Melanie Glaser, Hans Jörg Fricke, Klaus Höffken, Anita Heller, Anja Weise, Thomas Liehr
Pages: 417-423
Published online on: 01 February 2009

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Article

Short hairpin RNA (shRNA) constructs targeting high mobility group box-1 (HMGB1) expression leads to inhibition of prostate cancer cell survival and apoptosis

Munirathinam Gnanasekar, Sivasakthivel Thirugnanam, Kalyanasundaram Ramaswamy
Pages: 425-431
Published online on: 01 February 2009

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Article

Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7

Sven Saussez, Stèphanie Cludts, Aurelie Capouillez, Geoffrey Mortuaire, Karel Smetana, Herbert Kaltner, Sabine André, Xavier Leroy, Hans-Joachim Gabius, Christine Decaestecker
Pages: 433-439
Published online on: 01 February 2009

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Article

Altered expression of cyclin E and the retinoblastoma protein influences the effect of adjuvant therapy in breast cancer

Marie Ahnström Waltersson, Marie Stenmark Askmalm, Bo Nordenskjöld, Tommy Fornander, Lambert Skoog, Olle Stål
Pages: 441-448
Published online on: 01 February 2009

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Article Open Access

Different intracellular compartmentalization of TA and ΔNp73 in non-small cell lung cancer

Angela Di Vinci, Fausto Sessa, Ida Casciano, Barbara Banelli, Francesca Franzi, Claudio Brigati, Giorgio Allemanni, Patrizia Russo, Lorenzo Dominioni, Massimo Romani
Pages: 449-456
Published online on: 01 February 2009

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Article

Gene expression profiling reveals overexpression of TSPAN13 in prostate cancer

Jose M. Arencibia, Susana Martín, Francisco J. Pérez-Rodríguez, Ana Bonnin
Pages: 457-463
Published online on: 01 February 2009

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Article

Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer

Lucy J. Knight, Joseph Burrage, Sarah R. Bujac, Carolyn Haggerty, Alexander Graham, Neil J. Gibson, Gillian Ellison, James W. Growcott, A. Nigel Brooks, Andrew M. Hughes, George Xinarianos, Georgios Nikolaidis, John K. Field, Triantafillos Liloglou
Pages: 465-471
Published online on: 01 February 2009

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Article

Chemokine receptor CXCR4 expression, function, and clinical implications in gastric cancer

Hyo Jin Lee, Seong Woo Kim, Ha Yon Kim, Shengjin Li, Hwan Jung Yun, Kyu Sang Song, Samyong Kim, Deog Yeon Jo
Pages: 473-480
Published online on: 01 February 2009

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Article

Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-β in parathyroid carcinomas

C. Christofer Juhlin, Felix Haglund, Andrea Villablanca, Lars Forsberg, Kerstin Sandelin, Robert Bränström, Catharina Larsson, Anders Höög
Pages: 481-492
Published online on: 01 February 2009

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Article

Meningiomas and schwannomas: molecular subgroup classification found by expression arrays

Victor Martinez-Glez, Carmen Franco-Hernandez, Luis Alvarez, Jose M. De Campos, Alberto Isla, Jesus Vaquero, Luis Lassaletta, Cacilda Casartelli, Juan A. Rey
Pages: 493-504
Published online on: 01 February 2009

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Article Open Access

Monitoring therapy in canine malignant lymphoma and leukemia with serum thymidine kinase 1 activity - evaluation of a new, fully automated non-radiometric assay

Henrik P. Von Euler, Patricio Rivera, Anne-Charlotte Aronsson, Christer Bengtsson, Lars-Olof Hansson, Staffan K. Eriksson
Pages: 505-510
Published online on: 01 February 2009

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Article

Molecular specific and cell selective cytotoxicity induced by a novel synthetic HLA-DR antibody mimic for lymphoma and leukemia

G. L. DeNardo, G. R. Mirick, S. Hok, S. J. DeNardo, L. A. Beckett, G. N. Adamson, R. L. Balhorn
Pages: 511-516
Published online on: 01 February 2009

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Article

Rassf3 is responsible in part for resistance to mammary tumor development in neu transgenic mice

Isabelle C. Jacquemart, Alison E.B. Springs, Wen Y. Chen
Pages: 517-528
Published online on: 01 February 2009

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Article

Capability of SART3109-118 peptide to induce cytotoxic T lymphocytes from prostate cancer patients with HLA class I-A11, -A31 and -A33 alleles

Elnisr Rashed Mohamed, Masayasu Naito, Yasunobu Terasaki, Yamei Niu, Shojiro Gohara, Nobukazu Komatsu, Shigeki Shichijo, Kyogo Itoh, Masanori Noguchi
Pages: 529-536
Published online on: 01 February 2009

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Article

microRNA expression profile in undifferentiated gastric cancer

Takeyasu Katada, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitui, Yoichiro Mori, Ryo Ogawa, Koshiro Harata, Yoshitaka Fujii
Pages: 537-542
Published online on: 01 February 2009

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Article

Differential effects of malignant mesothelioma cells on THP-1 monocytes and macrophages

Valerio Izzi, Valerio Chiurchiù, Fabiola D'Aquilio, Camilla Palumbo, Ilaria Tresoldi, Andrea Modesti, Patrizia M. Baldini
Pages: 543-550
Published online on: 01 February 2009

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Article

Targeted therapy of human osteosarcoma with 17AAG or rapamycin: Characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways

Yair Gazitt, Venkatasubbarao Kolaparthi, Karla Moncada, Charles Thomas, James Freeman
Pages: 551-561
Published online on: 01 February 2009

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Article

Targeting of CD4+CD25high cells while preserving CD4+CD25low cells with low-dose chimeric anti-CD25 antibody in adoptive immunotherapy of cancer

Riki Okita, Yoshiyuki Yamaguchi, Masahiro Ohara, Katsuji Hironaka, Makoto Okawaki, Ichiro Nagamine, Takuhiro Ikeda, Akiko Emi, Jun Hihara, Morihito Okada
Pages: 563-572
Published online on: 01 February 2009

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Article

The anti-leukemic effect of a novel histone deacetylase inhibitor MCT-1 and 5-aza-cytidine involves augmentation of Nur77 and inhibition of MMP-9 expression

H. B. Liu, M. T. Voso, D. Gumiero, J. Duong, J. J. McKendrick, A. E. Dear
Pages: 573-579
Published online on: 01 February 2009

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Article

Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton

Yi-Jang Lee, Cheng-Han Tsai, Jeng-Jong Hwang, Shu-Jun Chiu, Tzong-Jen Sheu, Peter C. Keng
Pages: 581-589
Published online on: 01 February 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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