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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2003 Volume 10 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Role of telomerase in radiocurability (Review)

Tej K. Pandita, Joseph L. Roti Roti
Pages: 263-270
Published online on: 01 March 2003

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Article

Reduction of dihydrodiol dehydrogenase expression in resected hepatocellular carcinoma

Mei-Due Yang, Cheng-Chung Wu, Shiow-Her Chiou, Chang-Fang Chiu, Tze-Yi Lin, I-Ping Chiang, Kuan-Chih Chow
Pages: 271-276
Published online on: 01 March 2003

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Article

Comparative analysis of K-ras point mutation, telomerase activity, and p53 overexpression in pancreatic tumours

Kenichiro Uemura, Eiso Hiyama, Yoshiaki Murakami, Tetsuya Kanehiro, Hiroki Ohge, Taijiro Sueda, Takashi Yokoyama
Pages: 277-283
Published online on: 01 March 2003

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Article

Expression of bcl-2 in oral squamous cell carcinoma: An immunohistochemical study of 90 cases with clinico-pathological correlations

L. Lo Muzio, M. D. Mignogna, G. Pannone, C. Rubini, R. Grassi, P. F. Nocini, F. Ferrari, R. Serpico, G. Favia, G. De Rosa, E. Maiorano
Pages: 285-291
Published online on: 01 March 2003

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Article

VBP-1 is necessary for morphogenesis in Caenorhabditis elegans

Harumi Ichimiya, Okio Hino, Yuji Kohara, Naoaki Ishii
Pages: 293-295
Published online on: 01 March 2003

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Article

Cyanidin 3-O-β-D-glucoside isolated from skin of black Glycine max and other anthocyanins isolated from skin of red grape induce apoptosis in human lymphoid leukemia Molt 4B cells

Hirotaka Katsuzaki, Hiroshige Hibasami, Shinji Ohwaki, Kengo Ishikawa, Kunio Imai, Kumiko Date, Yukinobu Kimura, Takashi Komiya
Pages: 297-300
Published online on: 01 March 2003

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Article

Papillary renal cell carcinoma in a young adult: serial changes in diagnostic images

Tatsuya Nakatani, Hiroyuki Iwata, Masato Kamizuru, Katsuyuki Kuratsukuri, Toshihide Naganuma, Kazunobu Sugimura
Pages: 301-303
Published online on: 01 March 2003

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Article

Expression of a novel splicing variant deleting exons 4 and 6 of the progesterone receptor gene is a rare event in breast cancer

Kumi Nagao, Norio Kohno, Kazuyuki Wakita, Kazumasa Hikiji, Shigeki Yamamoto, Hiroyuki Hirata, Hisashi Hisatomi
Pages: 305-308
Published online on: 01 March 2003

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Article

Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer

Yukihiro Funada, Tsuyoshi Noguchi, Ryuichi Kikuchi, Shinsuke Takeno, Yuzo Uchida, Helmut E. Gabbert
Pages: 309-313
Published online on: 01 March 2003

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Article

Sentinel lymph node navigation surgery for pancreatic head cancers

Tetsuo Ohta, Hirohisa Kitagawa, Masato Kayahara, Shin-Ichi Kinami, Itasu Ninomiya, Sachio Fushida, Takashi Fujimura, Gen-Ichi Nishimura, Koichi Shimizu, Shuangqin Yi, Koichi Miwa
Pages: 315-319
Published online on: 01 March 2003

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Article

S-phase kinase-associated protein 2 expression in laryngeal squamous cell carcinomas and its prognostic implications

Youyi Dong, Li Sui, Yasuo Watanabe, Katsuyoshi Sugimoto, Masaaki Tokuda
Pages: 321-325
Published online on: 01 March 2003

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Article

Immunohistochemical analysis of transforming growth factor β in gallbladder cancer

Keiichi Kitamura, Kazuhiko Kasuya, Akihiko Tsuchida, Akihiro Mimuro, Keiichiro Inoue, Toshiaki Aoki, Tatsuya Aoki, Yasuhisa Koyanagi
Pages: 327-332
Published online on: 01 March 2003

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Article

Histone H4 acetylation and histone deacetylase 1 expression in esophageal squamous cell carcinoma

Yasushi Toh, Manabu Yamamoto, Kazuya Endo, Yasuharu Ikeda, Hideo Baba, Shunji Kohnoe, Hirotoshi Yonemasu, Yoichi Hachitanda, Takeshi Okamura, Keizo Sugimachi
Pages: 333-338
Published online on: 01 March 2003

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Article

Immunohistochemical analysis of cyclooxygenase-2 and vascular endothelial growth factor in pancreaticobiliary maljunction

Akihiko Tsuchida, Yuichi Nagakawa, Kazuhiko Kasuya, Takao Itoi, Mitsufumi Endo, Takashi Ozawa, Tatsuya Aoki, Yasuhisa Koyanagi
Pages: 339-343
Published online on: 01 March 2003

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Article

Expression of matrix metalloproteinases in human transitional cell carcinoma of the urinary bladder

Toshiyuki Sumi, Hiroyuki Yoshida, Yoji Hyun, Tomoyo Yasui, Yoshinari Matsumoto, Kanae Hattori, Kazunobu Sugimura, Hidenori Kawashima, Tatsuya Nakatani, Osamu Ishiko
Pages: 345-349
Published online on: 01 March 2003

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Article

Identification of markers of possible prognostic value in 57 giant cell tumors of bone

Gabriella Gamberi, Massimo Serra, Paola Ragazzini, Giovanna Magagnoli, Laura Pazzaglia, Francesca Ponticelli, Cristina Ferrari, Manuela Zanasi, Franco Bertoni, Piero Picci, M. Serena Benassi
Pages: 351-356
Published online on: 01 March 2003

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Article

Real-Time RT-PCR of tyrosine hydroxylase to detect bone marrow involvement in advanced neuroblastoma

Andrea Pession, Virginia Libri, Roberta Sartini, Rosa Conforti, Elisabetta Magrini, Livia Bernardi, Raffaele Fronza, Eleonora Olivotto, Arcangelo Prete, Roberto Tonelli, Guido Paolucci
Pages: 357-362
Published online on: 01 March 2003

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Article

Effect of the number of uninvolved nodes on survival in early breast cancer

Vincent Vinh-Hung, Gàbor Cserni, Tomasz Burzykowski, Jan Van De Steene, Mia Voordeckers, Guy Storme
Pages: 363-368
Published online on: 01 March 2003

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Article

Prognostic value of Bak expression in oral tongue squamous cell carcinomas

Xin Xie, Ole Petter F. Clausen, Morten Boysen
Pages: 369-374
Published online on: 01 March 2003

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Article

A water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia suppresses azoxymethane-induction of colon cancers in male F344 rats

Huimei Lu, Eikai Kyo, Toshihiro Uesaka, Osamu Katoh, Hiromitsu Watanabe
Pages: 375-379
Published online on: 01 March 2003

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Article

Preoperative combination chemotherapy with S-1 and low dose cisplatin against highly advanced gastric carcinoma

Yoshiro Saikawa, Yoshikiyo Akasaka, Toshio Kanai, Yoshihide Otani, Koichiro Kumai, Tetsuro Kubota, Masaki Kitajima
Pages: 381-386
Published online on: 01 March 2003

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Article

A new thin-type bronchoscope improves diagnostic accuracy of peripheral pulmonary carcinoma

Akira Iyoda, Makoto Suzuki, Masako Chiyo, Yasumitsu Moriya, Kazuhiro Yasufuku, Shigetoshi Yoshida, Yasuo Sekine, Kiyoshi Shibuya, Toshihiko Iizasa, Yukio Saitoh, Kenzo Hiroshima, Masayuki Baba, Takehiko Fujisawa
Pages: 387-389
Published online on: 01 March 2003

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Article

The preventive effect of antineoplaston AS2-1 on HCC recurrence

Hideaki Tsuda, Michio Sata, Tutomu Kumabe, Masafumi Uchida, Hiroshi Hara
Pages: 391-397
Published online on: 01 March 2003

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Article

External beam radiotherapy in bone metastatic prostate cancer: Impact on patients' pain relief and quality of life

Giuseppe Di Lorenzo, Riccardo Autorino, Fortunato Ciardiello, David Raben, Cataldo Bianco, Teresa Troiani, Carmine Pizza, Michele De Laurentiis, Matilde Pensabene, Massimo D'Armiento, A. Raffaele Bianco, Sabino De Placido
Pages: 399-404
Published online on: 01 March 2003

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Article

Expression of tetraspanin adaptor proteins below defined threshold values is associated with in vitro invasiveness of mammary carcinoma cells

Georg Sauer, Christian Kurzeder, Regina Grundmann, Rolf Kreienberg, Robert Zeillinger, Helmut Deissler
Pages: 405-410
Published online on: 01 March 2003

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Article

Increased serum midkine concentration as a possible tumor marker in patients with superficial esophageal cancer

Hideaki Shimada, Yoshihiro Nabeya, Shin-Ichi Okazumi, Hisahiro Matsubara, Kenji Kadomatsu, Takashi Muramatsu, Shinya Ikematsu, Sadatoshi Sakuma, Takenori Ochiai
Pages: 411-414
Published online on: 01 March 2003

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Article

Thermoradiotherapy combined with adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines

Yuzuru Higuchi, Jun-Ichi Asaumi, Jun Murakami, Hidenobu Matsuzaki, Toru Wakasa, Tetsuyoshi Inoue, Hironobu Konoucni, Miki Hisatomi, Yoshinobu Yanagi, Yasutoshi Honda, Hiroshi Shigehara, Kanji Kishi
Pages: 415-420
Published online on: 01 March 2003

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Article

Promotion effects of hot water on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in F344 rats

Zhi Gang Li, Yutaka Shimada, Fumiaki Sato, Masato Maeda, Atsushi Itami, Junichi Kaganoi, Izumi Komoto, Atsushi Kawabe, Masayuki Imamura
Pages: 421-426
Published online on: 01 March 2003

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Article

Immunohistological study of cell cycle-related factors, oncogene expression, and cell proliferation in adenocarcinoma developed in Barrett's esophagus

Teruhiko Fujii, Shino Nakagawa, Mai Hanzawa, Susumu Sueyoshi, Hiromasa Fujita, Kazuo Shirouzu, Hideaki Yamana
Pages: 427-431
Published online on: 01 March 2003

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Article

Neoadjuvant chemotherapy with CDDP and 5-fluorouracil for gastric cancer with serosal invasion

Nobuhiro Takiguchi, Masao Nunomura, Keiji Koda, Kenji Oda, Hirofumi Suzuki, Masaru Miyazaki
Pages: 433-438
Published online on: 01 March 2003

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Article

Clinicopathologic characteristics related to the high variability of coding mononucleotide repeat sequences in tumors with high-microsatellite instability

Kyung Young Chung, Nam-Gyun Kim, Long Shan Li, Haeryoung Kim, Hyunki Kim, Chung Mo Nam, Hoguen Kim, Dong-Hwan Shin
Pages: 439-444
Published online on: 01 March 2003

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Article

Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer

Hiroki Kuniyasu, Yoshitomo Chihara, Tadateru Takahashi
Pages: 445-448
Published online on: 01 March 2003

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Review

Epidemiology and pathogenesis of esophageal cancer: Management and its controversial results (Review)

G. P. Stathopoulos, N. Tsiaras
Pages: 449-454
Published online on: 01 March 2003

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Article

Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression

Hitoshi Miyashita, Shiro Mori, Katutoshi Motegi, Manabu Fukumoto, Takafumi Uchida
Pages: 455-461
Published online on: 01 March 2003

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Article

Determinants of the interval between diagnosis and treatment in patients with digestive tract cancer

M. Mariscal, J. Llorca, D. Prieto-Salceda, S. Palma, M. Delgado-Rodríguez
Pages: 463-467
Published online on: 01 March 2003

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Article

Resistance to cytotoxic chemotherapy-induced apoptosis in human prostate cancer cells is associated with intracellular clusterin expression

Hideaki Miyake, Isao Hara, Sadao Kamidono, Martin E. Gleave, Hiroshi Eto
Pages: 469-473
Published online on: 01 March 2003

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Article

Evaluation of different markers in non-small cell lung cancer: Prognostic value of clinical staging, tumour cell detection and tumour marker analysis for tumour progression and overall survival

Sabine Kasimir-Bauer, Norbert Schleucher, Rainer Weber, Rainer Neumann, Siegfried Seeber
Pages: 475-482
Published online on: 01 March 2003

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Article

Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation

Joo-Ho Shin, Ja-Lok Ku, Ki-Hyuk Shin, Young-Kyoung Shin, Sung-Bum Kang, Jae-Gahb Park
Pages: 483-486
Published online on: 01 March 2003

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Article

Low frequency of human polyomavirus BKV and JCV DNA in urothelial carcinomas of the renal pelvis and renal cell carcinomas

Antje Knöll, Robert Stoehr, Wolfgang Jilg, Arndt Hartmann
Pages: 487-491
Published online on: 01 March 2003

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Article

Meizothrombin, an intermediate of prothrombin cleavage potently activates renal carcinoma cells by interaction with PAR-type thrombin receptors

R. Kaufmann, U. Junker, M. Schilli-Westermann, C. Klötzer, J. Scheele, K. Junker
Pages: 493-496
Published online on: 01 March 2003

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Article

β-sitosterol, a plant sterol, induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells

Atif B. Awad, Rajat Roy, Carol S. Fink
Pages: 497-500
Published online on: 01 March 2003

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Article

Epigenetic control of E-cadherin (CDH1) by CpG methylation in metastasising laryngeal cancer

Pia Azarschab, Agnieszka Stembalska, Mirela Baus Loncar, Markus Pfister, Maria M. Sasiadek, Nikolaus Blin
Pages: 501-503
Published online on: 01 March 2003

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Article

Ultrasonographic detection of regional lymph node metastases in patients with intermediate or thick malignant melanoma

Elias N. Brountzos, Irene E. Panagiotou, Dimitrios I. Bafaloukos, Dimitrios A. Kelekis
Pages: 505-510
Published online on: 01 March 2003

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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