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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2004 Volume 12 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Low toxicity and anticancer activity of a novel liposomal cisplatin (Lipoplatin) in mouse xenografts

Teni Boulikas
Pages: 3-12
Published online on: 01 July 2004

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Article

The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse

Diana L. Hulboy, Shiva Gautam, Barbara Fingleton, Lynn M. Matrisian
Pages: 13-17
Published online on: 01 July 2004

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Article

Prediction of 5'-deoxy-5-fluorouridine sensitivity in colorectal cancer cases by thymidine phosphorylase activity and preliminary identification of susceptibility related genes

Koshi Mimori, Hiroaki Ueo, Tamotsu Kuroki, Takeshi Shiraishi, Shenoa Creer, Scott Taylor, Hideshi Ishii, Masaki Mori
Pages: 19-23
Published online on: 01 July 2004

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Article

Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma

Terence Kin-Wah Lee, Kwan Man, Ronnie Tung-Ping Poon, Chung-Mau Lo, Irene Oi-Lin Ng, Sheung-Tat Fan
Pages: 25-31
Published online on: 01 July 2004

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Article

Differences in genetic expression profiles between young-age and old-age gastric adenocarcinoma using cDNA microarray for endocrine disruptor study

Hye Won Chung, Seung Woo Park, Jae Bock Chung, Jin Kyung Kang, Ju Won Kim, Han-Soo Kim, Woo Jin Hyung, Sung Hoon Noh, Si Young Song
Pages: 33-39
Published online on: 01 July 2004

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Article

Protection against methotrexate toxicity by a soybean protein- and ω-3 fatty acid-containing diet: Comparative study with a casein-containing diet

Kenji Mitsugi, Tsuyoshi Nakamura, Norio Kashiwabara, Hiroshi Ariyama, Risa Tanaka, Eishi Baba, Minoru Nakamura, Mine Harada, Shuji Nakano
Pages: 41-45
Published online on: 01 July 2004

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Article

Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3

Makoto Saino, Tomoko Maruyama, Takao Sekiya, Takamasa Kayama, Yoshinori Murakami
Pages: 47-52
Published online on: 01 July 2004

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Article

Suppression of peritoneal metastasis in human gastric carcinoma by enhanced immunogenicity of B7-1 transfection

Yoji Sakate, Masakazu Yashiro, Hiroaki Tanaka, Kinshi Kosaka, Masaichi Ohira, Kosei Hirakawa
Pages: 53-57
Published online on: 01 July 2004

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Article

Criteria for predicting the recurrence and metastasis of stage I and II gastric cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Tomomi Kimura, Nobukazu Komatsu, Hiromi Ninomiya, Hisao Nakasaki, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 59-62
Published online on: 01 July 2004

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Article

Accuracy of criteria for predicting recurrence and metastasis in stage II and III gastric cancer patients with lymph node metastasis

Masaya Mukai, Shinkichi Sato, Nobukazu Komatsu, Tomomi Kimura, Hiromi Ninomiya, Midori Kawada, Hisao Nakasaki, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 63-66
Published online on: 01 July 2004

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Article

The use of self-expandable metal stents in the palliation of malignant bowel obstruction

M. I. Okorie, S. A. Hussain, P. L. Riley, I. J. McCafferty
Pages: 67-71
Published online on: 01 July 2004

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Article

Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy

Shohei Kohno, Kou Nakagawa, Katsuyuki Hamada, Hironobu Harada, Kenshi Yamasaki, Koji Hashimoto, Masatoshi Tagawa, Shigeyuki Nagato, Koji Furukawa, Takanori Ohnishi
Pages: 73-78
Published online on: 01 July 2004

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Article

New approaches in the diagnostic procedure of malignant pleural effusions

Daniela Terracciano, Angelina Di Carlo, Paolino Papa, Marcello Cicalese, Pierpaolo Maietta, Ciriaco Cecere, Angela Mariano, Vincenzo Macchia
Pages: 79-83
Published online on: 01 July 2004

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Article

Sensitivity of scirrhous gastric cancer to 5-fluorouracil and the role of cancer cell-stromal fibroblast interaction

Koichi Nakajima, Yutaka Okita, Shozo Matsuda
Pages: 85-90
Published online on: 01 July 2004

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Article

1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene a novel anticancer compound effective against tumor cell lines characterized by different mechanisms of resistance

Marino Novi, Massimo Ottone, Carlo Dell'Erba, Federica Barbieri, Barbara Chiavarina, Massimo Maccagno, Maurizio Viale
Pages: 91-96
Published online on: 01 July 2004

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Article

Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia

Chise Matsushita, Yang Yang, Seisho Takeuchi, Masahide Matsushita, Jacques J.M. Van Dongen, Tomasz Szczepanski, Claus R. Bartram, Hiromi Seo, H. Phillip Koeffler, Hirokuni Taguchi
Pages: 97-99
Published online on: 01 July 2004

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Article

High frequency methylation of p16INK4A gene during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis

Yuuji Nakahara, Satoru Shintani, Mariko Mihara, Tomohiro Matsumura, Hiroyuki Hamakawa
Pages: 101-106
Published online on: 01 July 2004

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Article

Expression of DOL54 is not restricted to myxoid liposarcomas with the FUS-DDIT3 chimera but is found in various sarcomas

Ioannis Panagopoulos, Fredrik Mertens, Margareth Isaksson, Nils Mandahl
Pages: 107-110
Published online on: 01 July 2004

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Article

Updating trends in cutaneous cancers in south-east Belgium

Isabelle Uhoda, Pascale Quatresooz, Isabelle Fumal, Arjen F. Nikkels, Claudine Pierard-Franchimont, Gerald E. Pierard
Pages: 111-114
Published online on: 01 July 2004

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Article

A convenient murine model for the study of intra-abdominal lymph node metastasis

Shozo Ishibashi, Kazuya Sonoda, Kyuzo Fujii, Koichi Ishikawa, Norio Shiraishi, Seigo Kitano
Pages: 115-118
Published online on: 01 July 2004

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Article

Ceramide triggers caspase activation during γ-radiation-induced apoptosis of human glioma cells lacking functional p53

Shigeru Hara, Shigeru Nakashima, Tohru Kiyono, Motoshi Sawada, Shin-Ichi Yoshimura, Toru Iwama, Noboru Sakai
Pages: 119-123
Published online on: 01 July 2004

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Article

Quantitative assessment of HER2/neu expression by real-time PCR and fluorescent in situ hybridization analysis in low-grade osteosarcoma

Woo-In Lee, Patrizia Bacchni, Franco Bertoni, Young Hee Maeng, Yong-Koo Park
Pages: 125-128
Published online on: 01 July 2004

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Article

Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers

Hio Chung Kang, Il-Jin Kim, Jae-Hyun Park, Yong Shin, Hye-Won Park, Ja-Lok Ku, Han-Kwang Yang, Kuhn Uk Lee, Kuk Jin Choe, Jae-Gahb Park
Pages: 129-133
Published online on: 01 July 2004

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Article

Oxaliplatin/rituximab combination in the treatment of intermediate-low grade non-Hodgkin's lymphoma of elderly patients

Raffaele Addeo, Michele Caraglia, Raffaele Costanzo, Vincenzo Faiola, Liliana Montella, Alberto Abbruzzese, Salvatore Del Prete
Pages: 135-140
Published online on: 01 July 2004

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Article

Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers

Atsushi Teramoto, Kazunori Tsukuda, Masaaki Yano, Shinichi Toyooka, Hideaki Dote, Hiroyoshi Doihara, Nobuyoshi Shimizu
Pages: 141-144
Published online on: 01 July 2004

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Article

Prognostic significance of cancer-testis gene expression in resected non-small cell lung cancer patients

Giulio Melloni, Andres J.M. Ferreri, Vincenzo Russo, Luca Gattinoni, Gianluigi Arrigoni, Giovanni Luca Ceresoli, Piero Zannini, Catia Traversari
Pages: 145-151
Published online on: 01 July 2004

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Article

Non-random distribution of chromatid breaks in lymphocytes of laryngeal squamous cell carcinoma patients

Marzena Gajecka, Malgorzata Jarmuzs, Witold Szyfter, Krzysztof Szyfter
Pages: 153-157
Published online on: 01 July 2004

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Article

Study of the combined effect of X-irradiation and epigallocatechin-gallate (a tea component) on the growth inhibition and induction of apoptosis in human cancer cell lines

Sarah Baatout, Paul Jacquet, Hanane Derradji, Daniella Ooms, Arlette Michaux, Max Mergeay
Pages: 159-167
Published online on: 01 July 2004

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Article

Relation between HPV-DNA and expression of p53, bcl-2, p21WAF-1, MIB-1, HER-2/neu and DNA ploidy in early cervical carcinoma: Correlation with clinical outcome

M. Graflund, B. Sorbe, S. Sigurdardóttir, M. G. Karlsson
Pages: 169-176
Published online on: 01 July 2004

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Article

DNA methylation of multiple genes and clinicopathological relationship of non-small cell lung cancers

Tetsuro Hanabata, Kazunori Tsukuda, Shinichi Toyooka, Masaaki Yano, Motoi Aoe, Itaru Nagahiro, Yoshifumi Sano, Hiroshi Date, Nobuyoshi Shimizu
Pages: 177-180
Published online on: 01 July 2004

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Article

Response of T- and B-lymphocytes in the spleen of mammary tumor-bearing rats to treatment with tamoxifen and soluble tumor-associated antigens

Herzl Ben-Hur, George Kossoy, Helena Sanko, Daniel Geva, Nina Shumlin, Itshak Zusman, Asher Elhayany
Pages: 181-185
Published online on: 01 July 2004

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Article

Cellular response of X-ray sensitive hamster mutant cell lines to gemcitabine, cisplatin and 5-fluorouracil

J. Haveman, N. Castro Kreder, H. M. Rodermond, C. Van Bree, N. A.P. Franken, L. J.A. Stalpers, M. Z. Zdzienicka, G. J. Peters
Pages: 187-192
Published online on: 01 July 2004

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Article

8-Chloro-adenosine sensitizes a human hepatoma cell line to TRAIL-induced apoptosis by caspase-dependent and -independent pathways

Mingjie Wang, Yanxin Liu, Shilian Liu, Dexian Zheng
Pages: 193-199
Published online on: 01 July 2004

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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