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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2009 Volume 21 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Fluorescence diagnosis and flat lesions of urothelium: New challenges for pathologists and urologists (Review)

Eva Compérat, Pierre Conort, Morgan Roupret, Fréderique Capron, Philippe Camparo, Rodolfo Montironi
Pages: 839-844
Published online on: 01 April 2009

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Review

Breast cancer as a mitochondrial disorder (Review)

Katarzyna Plak, Anna M. Czarnecka, Tomasz Krawczyk, Pawel Golik, Ewa Bartnik
Pages: 845-851
Published online on: 01 April 2009

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Article

Expression of the prolyl isomerase Pin1 is a useful indicator of sensitivity to chemoradiotherapy in advanced esophageal squamous cell carcinoma

Minoru Fukuchi, Yasuyuki Fukai, Makoto Sohda, Tatsuya Miyazaki, Masanobu Nakajima, Takanori Inose, Naritaka Tanaka, Katsuhiko Tsukada, Hiroyuki Kato, Hiroyuki Kuwano
Pages: 853-859
Published online on: 01 April 2009

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Article

A study on the mechanism of 5-aminolevulinic acid photodynamic therapy in vitro and in vivo in cervical cancer

Gui-Fang He, Mei-Lu Bian, Ya-Wei Zhao, Qing Xiang, Hong-Yan Li, Cheng Xiao
Pages: 861-868
Published online on: 01 April 2009

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Article

Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line

Emi Segawa, Susumu Hashitani, Yukiyo Toyohara, Hiromitsu Kishimoto, Kazuma Noguchi, Kazuki Takaoka, Masahiro Urade
Pages: 869-874
Published online on: 01 April 2009

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Article

Co-expression of keratinocyte growth factor and K-sam is an independent prognostic factor in gastric carcinoma

Takahiro Toyokawa, Masakazu Yashiro, Kosei Hirakawa
Pages: 875-880
Published online on: 01 April 2009

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Article

A preoperative evaluation for neo-infantile liver tumors using a three-dimensional reconstruction of multidetector row CT

Yoshiaki Kinoshita, Ryota Souzaki, Tatsuro Tajiri, Satoshi Ieiri, Makoto Hashizume, Tomoaki Taguchi
Pages: 881-886
Published online on: 01 April 2009

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Case Report

Malignant melanoma with a rhabdoid phenotype exhibiting numerous solid tumor masses: A case report

Tomoki Nakamura, Akihiko Matsumine, Hiroaki Kato, Katsuyuki Kusuzaki, Keisuke Nishimura, Tetsuya Murata, Taizo Shiraishi, Yoshinao Oda, Masazumi Tsuneyoshi, Atsumasa Uchida
Pages: 887-891
Published online on: 01 April 2009

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Article

Estrogen and progestin regulate HIF-1α expression in ovarian cancer cell lines via the activation of Akt signaling transduction pathway

Keqin Hua, Jingxin Din, Qi Cao, Weiwei Feng, Ying Zhang, Liangqin Yao, Yan Huang, Yuqin Zhao, Youji Feng
Pages: 893-898
Published online on: 01 April 2009

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Case Report

A gastrointestinal stromal tumor presenting as a pelvic mass: A case report

Roberto Angioli, Cleonice Battista, Ludovico Muzii, Giovanna Madonna Terracina, Ester Valentina Cafà, Maria Isabella Sereni, Roberto Montera, Francesco Plotti, Carla Rabitti, Pierluigi Benedetti Panici
Pages: 899-902
Published online on: 01 April 2009

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Article

Differential expression of osteocalcin during the metastatic progression of prostate cancer

Thomas A. Gardner, Sang-Jin Lee, Sang-Don Lee, Xiong Li, Toshihiro Shirakawa, Dong Deuk Kwon, Ra Young Park, Kyu Youn Ahn, Chaeyong Jung
Pages: 903-908
Published online on: 01 April 2009

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Article

Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo

Min Yu, Junli Gong, Mingxing Ma, Hui Yang, Jianhua Lai, Hong Wu, Lin Li, Lamei Li, Deyong Tan
Pages: 909-915
Published online on: 01 April 2009

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Article

Influence of microenvironments on microcirculation patterns and tumor invasion-related protein expression in melanoma

Luxia Chen, Baocun Sun, Shiwu Zhang, Xiulan Zhao, Yanjin He, Shaozhen Zhao, Tingting Lin, Xiaorong Li
Pages: 917-923
Published online on: 01 April 2009

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Article

Overexpression of the LKB1 gene inhibits lung carcinoma cell proliferation partly through degradation of c-myc protein

Xuan Liang, Ke-Jun Nan, Zhao-Lun Li, Qing-Zhi Xu
Pages: 925-931
Published online on: 01 April 2009

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Article

Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels

Caren Jayasinghe, Nektaria Simiantonaki, Romi Michel-Schmidt, Charles James Kirkpatrick
Pages: 933-939
Published online on: 01 April 2009

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Article

Hepatitis B virus DNA-induced carcinogenesis of human normal liver cells by virtue of nonmethylated CpG DNA

Xudong Liu, Qihuan Xu, Wei Chen, Hong Cao, Rongjiong Zheng, Gang Li
Pages: 941-947
Published online on: 01 April 2009

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Article

Influence of basic fibroblast growth factor on the growth of HeLa cells and the expression of angiogenin

Jianli Yang, Ji Wang, Jia Zhao, Dan Zuo, Xingrong Li, Li Wang
Pages: 949-955
Published online on: 01 April 2009

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Article

Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma

Chanisa Chuaysri, Peti Thuwajit, Anucha Paupairoj, Siri Chau-In, Tuangporn Suthiphongchai, Chanitra Thuwajit
Pages: 957-969
Published online on: 01 April 2009

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Article

Assessment of human papillomavirus and Epstein-Barr virus in lung adenocarcinoma

Wan-Teck Lim, Khoon Leong Chuah, Swan Swan Leong, Eng Huat Tan, Chee Keong Toh
Pages: 971-975
Published online on: 01 April 2009

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Article

Crosstalk between adenosine receptor (A2A isoform) and ERα mediates ethanol action in MCF-7 breast cancer cells

Nicolas Etique, Isabelle Grillier-Vuissoz, Julie Lecomte, Stephane Flament
Pages: 977-981
Published online on: 01 April 2009

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Article

Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development

Yu-Mei Ding, Ji-Hua Dong, Li-Li Chen, Han-Dong Zhang
Pages: 983-987
Published online on: 01 April 2009

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Article

A pilot study of vasculogenic mimicry immunohistochemical expression in intraocular melanoma model

Luxia Chen, Shiwu Zhang, Xiaorong Li, Baocun Sun, Xiulan Zhao, Danfang Zhang, Shaozhen Zhao
Pages: 989-994
Published online on: 01 April 2009

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Article

More than 45% of A549 and H446 cells are cancer initiating cells: Evidence from cloning and tumorigenic analyses

Xiangjiao Meng, Xiuwen Wang, Yawei Wang
Pages: 995-1000
Published online on: 01 April 2009

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Article

Mutational analysis of Smad7 in human cervical cancer

Ramkumar Hariharan, Janki Mohan Babu, Rema P, M. Radhakrishna Pillai
Pages: 1001-1004
Published online on: 01 April 2009

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Article

Phase I study of combination chemotherapy with irinotecan hydrochloride and nedaplatin for cervical squamous cell carcinoma: Japanese gynecologic oncology group study

Kaichiro Yamamoto, Katsuji Kokawa, Naohiko Umesaki, Ryuichiro Nishimura, Kazuo Hasegawa, Ikuo Konishi, Fumitaka Saji, Masato Nishida, Hiroshi Noguchi, Ken Takizawa
Pages: 1005-1009
Published online on: 01 April 2009

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Article

Beta-interferon, retinoids and tamoxifen in metastatic breast cancer: Long-term follow-up of a phase II study

Francesco Recchia, Gigliola Sica, Giampiero Candeloro, Stefano Necozione, Roberta Bisegna, Massimo Bratta, Silvio Rea
Pages: 1011-1016
Published online on: 01 April 2009

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Article

Novel cell culture model for prevention of carcinogenic risk in familial adenomatous polyposis syndrome

Nitin Telang, Meena Katdare
Pages: 1017-1021
Published online on: 01 April 2009

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Article

Correlation between efficacy and skin rash occurrence following treatment with the epidermal growth factor receptor inhibitor cetuximab: A single institution retrospective analysis

Michele Orditura, Ferdinando De Vita, Gennaro Galizia, Eva Lieto, Loredana Vecchione, Fabiana Vitiello, Erika Martinelli, Fortunato Ciardiello
Pages: 1023-1028
Published online on: 01 April 2009

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Article

Bone marrow stem cell damage after three different chemotherapy regimens for advanced Hodgkin's lymphoma

Paolo G. Gobbi, Francesco Valentino, Marco Danova, Fortunato Morabito, Bianca Rovati, Caterina Mammi, Massimo Gentile, Francesco Merli, Caterina Stelitano, Stefano Luminari, Gianni Quintana, Emilio Iannitto, Maura Brugiatelli, Massimo Federico
Pages: 1029-1035
Published online on: 01 April 2009

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Article

Expression of 5-fluorouracil-related enzymes in lung cancer: ELISA characterizes enzyme activity and messenger RNA expression

Masanori Tsuchida, Yasushi Yamato, Takehisa Hashimoto, Hirohiko Shinohara, Hajime Umezu, Katsuo Yoshiya, Teruaki Koike, Jun-ichi Hayashi
Pages: 1037-1043
Published online on: 01 April 2009

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Article

Seventeen years of experience with ATRA-based therapy for acute promyelocytic leukaemia: Long-term follow-up of patients treated at S. Martino Hospital, Genoa

Marino Clavio, Anna Ghiso, Chiara Ghiggi, Mauro Spriano, Nicoletta Colombo, Raffaella Grasso, Riccardo Varaldo, Maurizio Miglino, Ivana Pierri, Francesca Olcese, Sara Aquino, Samantha Biasco, Enrico Balleari, Angelo Michele Carella, Mario Sessarego, Marco Gobbi
Pages: 1045-1052
Published online on: 01 April 2009

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Article

The role of Id-1 in chemosensitivity and epirubicin-induced apoptosis in bladder cancer cells

Hao Hu, Hui Ying Han, Yu Liang Wang, Xiao Peng Zhang, Chee Wai Chua, Y. C. Wong, Xiao Feng Wang, Ming Tat Ling, Ke Xin Xu
Pages: 1053-1059
Published online on: 01 April 2009

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Article

Clinical comparison of QOL and adverse events during postoperative adjuvant chemotherapy in outpatients with node-positive colorectal cancer or gastric cancer

Masaya Mukai, Kyoko Kishima, Fumino Uchiumi, Emi Ishibashi, Maki Fukasawa, Takayuki Tajima, Masato Nakamura, Hiroyasu Makuuchi
Pages: 1061-1066
Published online on: 01 April 2009

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Article

Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma

Shigeru Tsunoda, Eric Smith, Neville J. De Young, Xian Wang, Zi-Qing Tian, Jun-Feng Liu, Glyn G. Jamieson, Paul A. Drew
Pages: 1067-1073
Published online on: 01 April 2009

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Article

Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis

Jia-Jun Liu, Yong Zhang, Dong-Jun Lin, Ruo-Zhi Xiao
Pages: 1075-1081
Published online on: 01 April 2009

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Article

Enhanced effects of PPARγ ligands and RXR selective retinoids in combination to inhibit migration and invasiveness in cancer cells

A. Papi, P. Rocchi, A. M. Ferreri, F. Guerra, M. Orlandi
Pages: 1083-1089
Published online on: 01 April 2009

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Article

Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: Relationship to acute phase response and survival

Alastair G.W. Moses, Jean Maingay, Kathryn Sangster, Kenneth C.H. Fearon, James A. Ross
Pages: 1091-1095
Published online on: 01 April 2009

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Article

Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma

Kam-Wing Leung, Chen-Hsun Tsai, Michael Hsiao, Ching-Juinn Tseng, Luo-Ping Ger, Kuen-Haur Lee, Pei-Jung Lu
Pages: 1097-1104
Published online on: 01 April 2009

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Article

Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia

Alper Celik, Yoshihiko Kano, Shingo Tsujinaka, Sinichirou Okada, Koichi Takao, Masakazu Takagi, Shigeru Chohnan, Kuniyasu Soda, Masanobu Kawakami, Fumio Konishi
Pages: 1105-1111
Published online on: 01 April 2009

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Article

Role of CCL5 in invasion, proliferation and proportion of CD44+/CD24− phenotype of MCF-7 cells and correlation of CCL5 and CCR5 expression with breast cancer progression

Yimin Zhang, Feng Yao, Xiaoli Yao, Changhong Yi, Cheng Tan, Lei Wei, Shengrong Sun
Pages: 1113-1121
Published online on: 01 April 2009

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Article

Prognostic significance of altered expression of SDC2 and CYR61 in esophageal squamous cell carcinoma

Xin Huang, Da-Wei Xiao, Li-Yan Xu, Hai-Jun Zhong, Lian-Di Liao, Ze-Fen Xie, En-Min Li
Pages: 1123-1129
Published online on: 01 April 2009

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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