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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2003 Volume 23 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation

Juergen-Theodor Fraenzer, Huiqi Pan, Lauro Minimo, George M. Smith, Dan Knauer, Gene Hung
Pages: 1493-1500
Published online on: 01 December 2003

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Article

Novel photodynamic diagnosis of bladder cancer: Ex vivo fluorescence cytology using hypericin

Malini Olivo, Weber Lau, Vanaja Manivasager, R. Bhuvaneswari, Zheng Wei, Khee Chee Soo, Christopher Cheng, Puay Hoon Tan
Pages: 1501-1504
Published online on: 01 December 2003

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Article

Voacamine, a bisindolic alkaloid from Peschiera fuchsiaefolia, enhances the cytotoxic effect of doxorubicin on multidrug-resistant tumor cells

S. Meschini, M. Marra, A. Calcabrini, E. Federici, C. Galeffi, G. Arancia
Pages: 1505-1513
Published online on: 01 December 2003

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Article

Functional and expression analyses of mgl-1, a mouse orthologue of lethal giant larvae recessive oncogene

Yong-Soo Kim, Jihwan Song, Yukyung Kim, In-Ok Kim, Incheol Kang, Kwang-Hyun Baek
Pages: 1515-1519
Published online on: 01 December 2003

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Article

The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells

Anna De Blasio, Maria T. Musmeci, Michela Giuliano, Marianna Lauricella, Sonia Emanuele, Antonella D'Anneo, Barbara Vassallo, Giovanni Tesoriere, Renza Vento
Pages: 1521-1528
Published online on: 01 December 2003

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Article

In situ detection of telomeres by fluorescence in situ hybridization and telomerase activity in glioblastoma multiforme: Correlation with p53 status, EGFR, c-myc, MIB1, and Topoisomerase IIα protein expression

Clelia Miracco, M. Margherita De Santi, Pietro Luzi, Anna Vittoria Lalinga, Lorella Laurini, Maria Caterina De Nisi, Giuseppina Angeloni, Marco Brogi, Concetta Cardone, Antonietta Carducci, Felice Arcuri, Piero Tosi, Giovanni Rubino, Luigi Pirtoli
Pages: 1529-1535
Published online on: 01 December 2003

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Article

Loss of p57KIP2 is associated with colorectal carcinogenesis

Jia-Qing Li, Fei Wu, Hisashi Usuki, Akihito Kubo, Tsutomu Masaki, Jiro Fujita, Shuji Bandoh, Kousuke Saoo, Hijiri Takeuchi, Shigeki Kuriyama, Toshihiko Ishida, Katsumi Imaida
Pages: 1537-1543
Published online on: 01 December 2003

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Article

Effects of tamoxifen therapy on the expression of p27 protein in the endometrium of women with primary breast cancer

Adalberto Abraão Siufi, Ismael Dale Cotrim G. Da Silva, Rita De Cassia M. Dardes, Luiz Carlos Takita, Geraldo Rodrigues De Lima, Wagner José Gonçalves
Pages: 1545-1551
Published online on: 01 December 2003

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Article

Loss of EphB6 expression in metastatic melanoma

Christian Hafner, Frauke Bataille, Stefanie Meyer, Bernd Becker, Alexander Roesch, Michael Landthaler, Thomas Vogt
Pages: 1553-1559
Published online on: 01 December 2003

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Article

Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate

Jian-Wen Liu, Atsushi Kayasuga, Norio Nagao, Eiko Masatsuji-Kato, Toshi Tuzuki, Nobuhiko Miwa
Pages: 1561-1567
Published online on: 01 December 2003

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Article

A metastatic human prostate cancer model using intraprostatic implantation of tumor produced by PC-3 neolacZ transfected cells

Anastasia S. Tsingotjidou, Raj Ahluwalia, Xuguang Zhang, Heather Conrad, Christos Emmanouilides
Pages: 1569-1574
Published online on: 01 December 2003

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Article

Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elements

Nobuo Kondoh, Akiyuki Hada, Akihide Ryo, Masahiro Shuda, Masaaki Arai, Osamu Matsubara, Fumihiro Kimura, Toru Wakatsuki, Mikio Yamamoto
Pages: 1575-1583
Published online on: 01 December 2003

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Article

NK cell depletion results in accelerated tumor growth and attenuates the antitumor effect of total body irradiation

Glen M. Miller, Melba L. Andres, Daila S. Gridley
Pages: 1585-1592
Published online on: 01 December 2003

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Article

Transforming growth factor-β is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33

Albert H. Kim, Deborah A. Lebman, Christopher M. Dietz, Steven R. Snyder, Kerry W. Eley, Theodore D. Chung
Pages: 1593-1599
Published online on: 01 December 2003

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Article

Transcriptional regulation of the β1C integrin splice variant in human prostate adenocarcinoma

Loredana Moro, Margherita Greco, Pasquale Ditonno, Michele Battaglia, Ersilia Marra, Elda Perlino
Pages: 1601-1606
Published online on: 01 December 2003

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Article

Surrogate end-point biomarker analysis in a retinol chemoprevention trial in current and former smokers with bronchial dysplasia

Stephen Lam, Xiaochun Xu, Helga Parker-Klein, Jean C. Le Riche, Calum Macaulay, Martial Guillaud, Andy Coldman, Adi Gazdar, Reuben Lotan
Pages: 1607-1613
Published online on: 01 December 2003

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Article

Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray

Koichi Okada, Toyomasa Katagiri, Tatsuhiko Tsunoda, Yoichi Mizutani, Yasushi Suzuki, Masayuki Kamada, Tomoaki Fujioka, Taro Shuin, Tsuneharu Miki, Yusuke Nakamura
Pages: 1615-1635
Published online on: 01 December 2003

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Article

XK469, a topo IIβ inhibitor, induces apoptosis in Waldenstrom's macroglobulinemia through multiple pathways

Edith Mensah-Osman, Ayad Al-Katib, Mahmoud Dandashi, Ramzi Mohammad
Pages: 1637-1644
Published online on: 01 December 2003

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Article

Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells

Eun-Jung Lee, Ilchung Shin, Soon-Kyoung Kwon, Hea-Soon Shin, Aree Moon
Pages: 1645-1650
Published online on: 01 December 2003

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Article

Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma

Shipra Kaicker, Kimberly W. McCrudden, Leal Beck, Tamara New, Jianzhong Huang, Jason S. Frischer, Anna Serur, Angela Kadenhe-Chiweshe, Akiko Yokoi, Jessica J. Kandel, Darrell J. Yamashiro
Pages: 1651-1655
Published online on: 01 December 2003

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Article

Induction of Bax and activation of caspases during β-sitosterol-mediated apoptosis in human colon cancer cells

Yung Hyun Choi, Kyu Ri Kong, Young-Ae Kim, Keun-Ok Jung, Jeong-Ha Kil, Sook-Hee Rhee, Kun-Young Park
Pages: 1657-1662
Published online on: 01 December 2003

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Article

Promoter methylation of cyclin D2 gene in gastric carcinoma

Yasuhiro Oshimo, Hirofumi Nakayama, Reiko Ito, Yasuhiko Kitadai, Kazuhiro Yoshida, Kazuaki Chayama, Wataru Yasui
Pages: 1663-1670
Published online on: 01 December 2003

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Article

Expression of gicerin enhances the invasive and metastatic activities of a mouse mammary carcinoma cell line

Yasuhiro Tsukamoto, Takashi Sakaiuchi, Satoshi Hiroi, Masaru Furuya, Seiichiro Tsuchiya, Fumihiko Sasaki, Naomasa Miki, Eiichi Taira
Pages: 1671-1677
Published online on: 01 December 2003

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Article

Establishment of a novel human ovarian cancer cell line with high anchorage-independent growth ability

Yukiko Nishikawa, Yoshio Yoshida, Kazumi Kawahara, Tetsuji Kurokawa, Kimihisa Tajima, Fumikazu Kotsuji
Pages: 1679-1686
Published online on: 01 December 2003

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Article

Somatostatin receptor scintigraphy with 111In-pentetreotide in non-functioning gastroenteropancreatic neuroendocrine tumors

Orazio Schillaci, Angela Spanu, Francesco Scopinaro, Antonio Falchi, Vito Corleto, Roberta Danieli, Pietro Marongiu, Nicola Pisu, Giordano Madeddu, Gianfranco Delle Fave, Giuseppe Madeddu
Pages: 1687-1695
Published online on: 01 December 2003

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Article

Stimulation of CD40 inhibits Fas- or chemotherapy-mediated apoptosis and increases cell motility in human gastric carcinoma cells

Hiroshi Yamaguchi, Fumiaki Tanaka, Noriaki Sadanaga, Mitsuhiko Ohta, Hiroshi Inoue, Masaki Mori
Pages: 1697-1702
Published online on: 01 December 2003

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Article

Down-regulation of telomerase activity in malignant glioma cells by p27KIP1

Takao Kanzawa, Tadashi Komata, Satoru Kyo, Isabelle M. Germano, Yasuko Kondo, Seiji Kondo
Pages: 1703-1708
Published online on: 01 December 2003

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Article

Translational upregulation of yes accompanies eIF4E-mediated oncogenic transformation

Robert J. Defatta, Arrigo De Benedetti
Pages: 1709-1713
Published online on: 01 December 2003

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Article

Considerations on development, validation, application, and quality control of immuno(metric) biomarker assays in clinical cancer research: An EORTC-NCI working group report

Fred C.G.J. Sweep, Herbert A. Fritsche, Massimo Gion, George G. Klee, Manfred Schmitt
Pages: 1715-1726
Published online on: 01 December 2003

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Article

The PLC-PKC cascade is required for IL-1β-dependent Erk and Akt activation: their role in proliferation

A. R.M. Ruhul Amin, Yasukatu Ichigotani, Myat Lin Oo, M. Helal Uddin Biswas, Hong Yuan, Pengyu Huang, Naing Naing Mon, Michinari Hamaguchi
Pages: 1727-1731
Published online on: 01 December 2003

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Article

Eicosapentaenoic acid perturbs signalling via the NFκB transcriptional pathway in pancreatic tumour cells

James A. Ross, Jean P. Maingay, Kenneth C.H. Fearon, Kathryn Sangster, James J. Powell
Pages: 1733-1738
Published online on: 01 December 2003

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Article

HER2/neu uses Akt to suppress retinoic acid response element binding activity in MDA-MB-453 breast cancer cells

Doris R. Siwak, Edgar Mendoza-Gamboa, Ana M. Tari
Pages: 1739-1745
Published online on: 01 December 2003

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Article

Similar immune responses and antitumor effects of murine dendritic cells loaded with either exogenous or endogenous-synthesized protein

Roger Lacave, Carole Masurier, Martine Guigon, François M. Lemoine, David Klatzmann, Bruno M. Colombo
Pages: 1747-1753
Published online on: 01 December 2003

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Article

Alterations in mitochondria function and morphology in HT29 cells upon conditions inducing differentiation and apoptosis

Vlasta Sovová, Jitka Stokrová, Eva Sloncová, Dana Kucerová, Zdena Tuhácková, Jan Korb
Pages: 1755-1760
Published online on: 01 December 2003

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review)

Zhiyao Liu, Yuqiao Wang, Yali Wang, Yucheng Zhang
Article Number: 26
Published online on: 16 December 2025

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Advancements on the synergistic application of oncolytic viruses and molecularly targeted therapies for the treatment of solid tumors (Review)

Shiwen Bi, Tiyan Shan, Yong Tang, Qi Wang
Article Number: 25
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma

Gang Wu, Xiaojun Lu, Yawei Wang, Hui He, Xiangyu Meng, Shuguan Xia, Kunming Zhen, Yongfeng Liu
Article Number: 24
Published online on: 16 December 2025

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Review

CCDC137: A key hub for RNA and epigenetic regulation in cancer research (Review)

Xiaoying Zhao, Wenjing Zhang, Xiang Yu, Xiaohan Zhao, Xu Dai, Sirui Chen, Yan Wang, Jiang Cheng, Weiwei Zheng
Article Number: 23
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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