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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2003 Volume 23 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation

Juergen-Theodor Fraenzer, Huiqi Pan, Lauro Minimo, George M. Smith, Dan Knauer, Gene Hung
Pages: 1493-1500
Published online on: 01 December 2003

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Article

Novel photodynamic diagnosis of bladder cancer: Ex vivo fluorescence cytology using hypericin

Malini Olivo, Weber Lau, Vanaja Manivasager, R. Bhuvaneswari, Zheng Wei, Khee Chee Soo, Christopher Cheng, Puay Hoon Tan
Pages: 1501-1504
Published online on: 01 December 2003

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Article

Voacamine, a bisindolic alkaloid from Peschiera fuchsiaefolia, enhances the cytotoxic effect of doxorubicin on multidrug-resistant tumor cells

S. Meschini, M. Marra, A. Calcabrini, E. Federici, C. Galeffi, G. Arancia
Pages: 1505-1513
Published online on: 01 December 2003

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Article

Functional and expression analyses of mgl-1, a mouse orthologue of lethal giant larvae recessive oncogene

Yong-Soo Kim, Jihwan Song, Yukyung Kim, In-Ok Kim, Incheol Kang, Kwang-Hyun Baek
Pages: 1515-1519
Published online on: 01 December 2003

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Article

The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells

Anna De Blasio, Maria T. Musmeci, Michela Giuliano, Marianna Lauricella, Sonia Emanuele, Antonella D'Anneo, Barbara Vassallo, Giovanni Tesoriere, Renza Vento
Pages: 1521-1528
Published online on: 01 December 2003

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Article

In situ detection of telomeres by fluorescence in situ hybridization and telomerase activity in glioblastoma multiforme: Correlation with p53 status, EGFR, c-myc, MIB1, and Topoisomerase IIα protein expression

Clelia Miracco, M. Margherita De Santi, Pietro Luzi, Anna Vittoria Lalinga, Lorella Laurini, Maria Caterina De Nisi, Giuseppina Angeloni, Marco Brogi, Concetta Cardone, Antonietta Carducci, Felice Arcuri, Piero Tosi, Giovanni Rubino, Luigi Pirtoli
Pages: 1529-1535
Published online on: 01 December 2003

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Article

Loss of p57KIP2 is associated with colorectal carcinogenesis

Jia-Qing Li, Fei Wu, Hisashi Usuki, Akihito Kubo, Tsutomu Masaki, Jiro Fujita, Shuji Bandoh, Kousuke Saoo, Hijiri Takeuchi, Shigeki Kuriyama, Toshihiko Ishida, Katsumi Imaida
Pages: 1537-1543
Published online on: 01 December 2003

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Article

Effects of tamoxifen therapy on the expression of p27 protein in the endometrium of women with primary breast cancer

Adalberto Abraão Siufi, Ismael Dale Cotrim G. Da Silva, Rita De Cassia M. Dardes, Luiz Carlos Takita, Geraldo Rodrigues De Lima, Wagner José Gonçalves
Pages: 1545-1551
Published online on: 01 December 2003

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Article

Loss of EphB6 expression in metastatic melanoma

Christian Hafner, Frauke Bataille, Stefanie Meyer, Bernd Becker, Alexander Roesch, Michael Landthaler, Thomas Vogt
Pages: 1553-1559
Published online on: 01 December 2003

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Article

Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate

Jian-Wen Liu, Atsushi Kayasuga, Norio Nagao, Eiko Masatsuji-Kato, Toshi Tuzuki, Nobuhiko Miwa
Pages: 1561-1567
Published online on: 01 December 2003

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Article

A metastatic human prostate cancer model using intraprostatic implantation of tumor produced by PC-3 neolacZ transfected cells

Anastasia S. Tsingotjidou, Raj Ahluwalia, Xuguang Zhang, Heather Conrad, Christos Emmanouilides
Pages: 1569-1574
Published online on: 01 December 2003

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Article

Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elements

Nobuo Kondoh, Akiyuki Hada, Akihide Ryo, Masahiro Shuda, Masaaki Arai, Osamu Matsubara, Fumihiro Kimura, Toru Wakatsuki, Mikio Yamamoto
Pages: 1575-1583
Published online on: 01 December 2003

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Article

NK cell depletion results in accelerated tumor growth and attenuates the antitumor effect of total body irradiation

Glen M. Miller, Melba L. Andres, Daila S. Gridley
Pages: 1585-1592
Published online on: 01 December 2003

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Article

Transforming growth factor-β is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33

Albert H. Kim, Deborah A. Lebman, Christopher M. Dietz, Steven R. Snyder, Kerry W. Eley, Theodore D. Chung
Pages: 1593-1599
Published online on: 01 December 2003

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Article

Transcriptional regulation of the β1C integrin splice variant in human prostate adenocarcinoma

Loredana Moro, Margherita Greco, Pasquale Ditonno, Michele Battaglia, Ersilia Marra, Elda Perlino
Pages: 1601-1606
Published online on: 01 December 2003

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Article

Surrogate end-point biomarker analysis in a retinol chemoprevention trial in current and former smokers with bronchial dysplasia

Stephen Lam, Xiaochun Xu, Helga Parker-Klein, Jean C. Le Riche, Calum Macaulay, Martial Guillaud, Andy Coldman, Adi Gazdar, Reuben Lotan
Pages: 1607-1613
Published online on: 01 December 2003

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Article

Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray

Koichi Okada, Toyomasa Katagiri, Tatsuhiko Tsunoda, Yoichi Mizutani, Yasushi Suzuki, Masayuki Kamada, Tomoaki Fujioka, Taro Shuin, Tsuneharu Miki, Yusuke Nakamura
Pages: 1615-1635
Published online on: 01 December 2003

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Article

XK469, a topo IIβ inhibitor, induces apoptosis in Waldenstrom's macroglobulinemia through multiple pathways

Edith Mensah-Osman, Ayad Al-Katib, Mahmoud Dandashi, Ramzi Mohammad
Pages: 1637-1644
Published online on: 01 December 2003

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Article

Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells

Eun-Jung Lee, Ilchung Shin, Soon-Kyoung Kwon, Hea-Soon Shin, Aree Moon
Pages: 1645-1650
Published online on: 01 December 2003

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Article

Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma

Shipra Kaicker, Kimberly W. McCrudden, Leal Beck, Tamara New, Jianzhong Huang, Jason S. Frischer, Anna Serur, Angela Kadenhe-Chiweshe, Akiko Yokoi, Jessica J. Kandel, Darrell J. Yamashiro
Pages: 1651-1655
Published online on: 01 December 2003

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Article

Induction of Bax and activation of caspases during β-sitosterol-mediated apoptosis in human colon cancer cells

Yung Hyun Choi, Kyu Ri Kong, Young-Ae Kim, Keun-Ok Jung, Jeong-Ha Kil, Sook-Hee Rhee, Kun-Young Park
Pages: 1657-1662
Published online on: 01 December 2003

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Article

Promoter methylation of cyclin D2 gene in gastric carcinoma

Yasuhiro Oshimo, Hirofumi Nakayama, Reiko Ito, Yasuhiko Kitadai, Kazuhiro Yoshida, Kazuaki Chayama, Wataru Yasui
Pages: 1663-1670
Published online on: 01 December 2003

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Article

Expression of gicerin enhances the invasive and metastatic activities of a mouse mammary carcinoma cell line

Yasuhiro Tsukamoto, Takashi Sakaiuchi, Satoshi Hiroi, Masaru Furuya, Seiichiro Tsuchiya, Fumihiko Sasaki, Naomasa Miki, Eiichi Taira
Pages: 1671-1677
Published online on: 01 December 2003

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Article

Establishment of a novel human ovarian cancer cell line with high anchorage-independent growth ability

Yukiko Nishikawa, Yoshio Yoshida, Kazumi Kawahara, Tetsuji Kurokawa, Kimihisa Tajima, Fumikazu Kotsuji
Pages: 1679-1686
Published online on: 01 December 2003

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Article

Somatostatin receptor scintigraphy with 111In-pentetreotide in non-functioning gastroenteropancreatic neuroendocrine tumors

Orazio Schillaci, Angela Spanu, Francesco Scopinaro, Antonio Falchi, Vito Corleto, Roberta Danieli, Pietro Marongiu, Nicola Pisu, Giordano Madeddu, Gianfranco Delle Fave, Giuseppe Madeddu
Pages: 1687-1695
Published online on: 01 December 2003

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Article

Stimulation of CD40 inhibits Fas- or chemotherapy-mediated apoptosis and increases cell motility in human gastric carcinoma cells

Hiroshi Yamaguchi, Fumiaki Tanaka, Noriaki Sadanaga, Mitsuhiko Ohta, Hiroshi Inoue, Masaki Mori
Pages: 1697-1702
Published online on: 01 December 2003

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Article

Down-regulation of telomerase activity in malignant glioma cells by p27KIP1

Takao Kanzawa, Tadashi Komata, Satoru Kyo, Isabelle M. Germano, Yasuko Kondo, Seiji Kondo
Pages: 1703-1708
Published online on: 01 December 2003

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Article

Translational upregulation of yes accompanies eIF4E-mediated oncogenic transformation

Robert J. Defatta, Arrigo De Benedetti
Pages: 1709-1713
Published online on: 01 December 2003

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Article

Considerations on development, validation, application, and quality control of immuno(metric) biomarker assays in clinical cancer research: An EORTC-NCI working group report

Fred C.G.J. Sweep, Herbert A. Fritsche, Massimo Gion, George G. Klee, Manfred Schmitt
Pages: 1715-1726
Published online on: 01 December 2003

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Article

The PLC-PKC cascade is required for IL-1β-dependent Erk and Akt activation: their role in proliferation

A. R.M. Ruhul Amin, Yasukatu Ichigotani, Myat Lin Oo, M. Helal Uddin Biswas, Hong Yuan, Pengyu Huang, Naing Naing Mon, Michinari Hamaguchi
Pages: 1727-1731
Published online on: 01 December 2003

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Article

Eicosapentaenoic acid perturbs signalling via the NFκB transcriptional pathway in pancreatic tumour cells

James A. Ross, Jean P. Maingay, Kenneth C.H. Fearon, Kathryn Sangster, James J. Powell
Pages: 1733-1738
Published online on: 01 December 2003

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Article

HER2/neu uses Akt to suppress retinoic acid response element binding activity in MDA-MB-453 breast cancer cells

Doris R. Siwak, Edgar Mendoza-Gamboa, Ana M. Tari
Pages: 1739-1745
Published online on: 01 December 2003

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Article

Similar immune responses and antitumor effects of murine dendritic cells loaded with either exogenous or endogenous-synthesized protein

Roger Lacave, Carole Masurier, Martine Guigon, François M. Lemoine, David Klatzmann, Bruno M. Colombo
Pages: 1747-1753
Published online on: 01 December 2003

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Article

Alterations in mitochondria function and morphology in HT29 cells upon conditions inducing differentiation and apoptosis

Vlasta Sovová, Jitka Stokrová, Eva Sloncová, Dana Kucerová, Zdena Tuhácková, Jan Korb
Pages: 1755-1760
Published online on: 01 December 2003

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Momo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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