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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2004 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Inhibition of the cell cycle and induction of apoptosis by Noclosan™ and Loxat™ in cell lines irrespective of their origin

B. Schutte, M. Harmsa, G. Costongs, M. Henfling, M. Ummelen, W. Dignef, F. Ramaekers
Pages: 1357-1367
Published online on: 01 June 2004

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Article

Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal α-linolenic and γ-linolenic fatty acids: A novel mechanism by which dietary fat can alter mammary tumorigenesis

Javier A. Menendez, Santiago Ropero, Inderjit Mehmi, Ella Atlas, Ramon Colomer, Ruth Lupu
Pages: 1369-1383
Published online on: 01 June 2004

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Article

Cytogenetic and spectral karyotype analyses of benign and malignant cartilage tumours

Helene Sjögren, Charlotte Örndal, Ola Tingby, Jeanne M. Meis-Kindblom, Lars-Gunnar Kindblom, Göran Stenman
Pages: 1385-1391
Published online on: 01 June 2004

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Article

Quantification of disseminated tumor cells in the bloodstream of patients with hormone-refractory prostate carcinoma undergoing cytotoxic chemotherapy

Uta Schmidt, Udo Bilkenroth, Clemens Linné, Susanne Fuessel, Kai Kraemer, Michael Froehner, Manfred P. Wirth, Axel Meye
Pages: 1393-1399
Published online on: 01 June 2004

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Article

A role for protease-activated receptor-2 in pancreatic cancer cell proliferation

Rie Shimamoto, Tetsuji Sawada, Yasutake Uchima, Masafumi Inoue, Kenjiro Kimura, Yoshito Yamashita, Nobuya Yamada, Tamahiro Nishihara, Masaichi Ohira, Kosei Hirakawa
Pages: 1401-1406
Published online on: 01 June 2004

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Article

Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells

Kaname Nakatani, Junji Nishioka, Tatsuo Itakura, Yoshio Nakanishi, Jun-Ichi Horinouchi, Yasunori Abe, Hideo Wada, Tsutomu Nobori
Pages: 1407-1412
Published online on: 01 June 2004

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Article

Stimulation of cells from a non-invaded and an invaded lymph node with a HER-2+ tumor with peptides corresponding to T-cell epitopes E75 and G89 induced expansion of central memory cells (TCM) from the metastasis-negative lymph nodes

Byung K. Ko, Clay L. Efferson, Kouichiro Kawano, Henry M. Kuerer, Aysegul Sahin, James L. Murray, Constantin G. Ioannides
Pages: 1413-1418
Published online on: 01 June 2004

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Article

Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells

I. B. Appelskog, O. Ammerpohl, I. G. Svechnikova, W.-O. Lui, P. M. Almqvist, T. J. Ekström
Pages: 1419-1425
Published online on: 01 June 2004

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Article

Characteristics of a potent tumor vaccine-induced secondary anti-tumor T cell response

Yolanda D. Mahnke, Volker Schirrmacher
Pages: 1427-1434
Published online on: 01 June 2004

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Article

Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene

Tsutomu Kumazaki, Keiko Hiyama, Tomoko Takahashi, Hideaki Omatsu, Keiji Tanimoto, Takuya Noguchi, Eiso Hiyama, Youji Mitsui, Masahiko Nishiyama
Pages: 1435-1442
Published online on: 01 June 2004

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Article

Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells

Ian S. Zagon, Patricia J. McLaughlin
Pages: 1443-1448
Published online on: 01 June 2004

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Article

Potentiation of induction of apoptosis by sequential treatment with cisplatin followed by 5-fluorouracil in human oral cancer cells

Masayuki Azuma, Koji Harada, Supriatno, Tetsuya Tamatani, Katsumi Motegi, Yuki Ashida, Mitsunobu Sato
Pages: 1449-1455
Published online on: 01 June 2004

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Article

Identification of novel human neuronal leucine-rich repeat (hNLRR) family genes and inverse association of expression of Nbla10449/hNLRR-1 and Nbla10677/hNLRR-3 with the prognosis of primary neuroblastomas

Shiho Hamano, Miki Ohira, Eriko Isogai, Kounosuke Nakada, Akira Nakagawara
Pages: 1457-1466
Published online on: 01 June 2004

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Article

Antagonistic growth regulation of cell lines derived from human lung adenocarcinomas of Clara cell and aveolar type II cell lineage: Implications for chemoprevention

Hibret A. Adissu, Hildegard M. Schuller
Pages: 1467-1472
Published online on: 01 June 2004

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Article

Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling

Christopher B. Weldon, Amanda P. Parker, Daniel Patten, Steven Elliott, Yan Tang, Daniel E. Frigo, Christine M. Dugan, Erin L. Coakley, Nancy N. Butler, John L. Clayton, Jawed Alam, Tyler J. Curiel, Barbara S. Beckman, Bernard M. Jaffe, Matthew E. Burow
Pages: 1473-1480
Published online on: 01 June 2004

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Article

A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia

M. Sumi, T. Tauchi, G. Sashida, A. Nakajima, A. Gotoh, K. Shin-Ya, J. H. Ohyashiki, K. Ohyashiki
Pages: 1481-1487
Published online on: 01 June 2004

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Article

Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine

X. X. Wu, O. Ogawa, Y. Kakehi
Pages: 1489-1497
Published online on: 01 June 2004

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Article

ERK activation and subsequent RB phosphorylation are important determinants of the sensitivity to paclitaxel in lung adenocarcinoma cells

Hisashi Suyama, Tadashi Igishi, Hiroyuki Sano, Shingo Matsumoto, Yasushi Shigeoka, Hirofumi Nakanishi, Masahiro Endo, Naoto Burioka, Yutaka Hitsuda, Eiji Shimizu
Pages: 1499-1504
Published online on: 01 June 2004

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Article

Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide

Debra K. Kelleher, Oliver Thews, Avigdor Scherz, Yoram Salomon, Peter Vaupel
Pages: 1505-1511
Published online on: 01 June 2004

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Article

Proteomic analysis as related to transcriptome data in the lung of chromium(VI)-treated rats

Alberto Izzotti, Maria Bagnasco, Cristina Cartiglia, Mariagrazia Longobardi, Silvio De Flora
Pages: 1513-1522
Published online on: 01 June 2004

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Article

Therapeutic effects of novel anti-tumor reagent, apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line on human gastric carcinoma-bearing SCID mice

Aishun Jin, Yunlong Qi, Etsuko Mori, Maowu Guo, Seiichi Takasaki, Tsuneatsu Mori
Pages: 1523-1528
Published online on: 01 June 2004

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Article

Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients

L. Tessitore, B. Vizio, D. Pesola, F. Cecchini, A. Mussa, J. M. Argiles, C. Benedetto
Pages: 1529-1535
Published online on: 01 June 2004

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Article

K-ras codon 12 and 13 mutations are correlated with differential patterns of tumor cell dissemination in colorectal cancer patients

Michael Conzelmann, Ulrich Linnemann, Martin R. Berger
Pages: 1537-1544
Published online on: 01 June 2004

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Article

Gene expression analysis in SV40-immortalized human breast luminal epithelial cells with stem cell characteristics using a cDNA microarray

Joon-Suk Park, Dong-Young Noh, Seok-Hyun Kim, Sung-Hoon Kim, Gu Kong, Chia-Cheng Chang, Yong-Soon Lee, James E. Trosko, Kyung-Sun Kang
Pages: 1545-1558
Published online on: 01 June 2004

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Article

The p53-induced Wig-1 zinc finger protein is highly conserved from fish to man

Fredrik Hellborg, Klas G. Wiman
Pages: 1559-1564
Published online on: 01 June 2004

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Article

Epidermal growth factor upregulates matrix metalloproteinase-7 expression through activation of PEA3 transcription factors

Conor C. Lynch, Howard C. Crawford, Lynn M. Matrisian, Susan McDonnell
Pages: 1565-1572
Published online on: 01 June 2004

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Article

Exogenous expression of H-cadherin in CHO cells regulates contact inhibition of cell growth by inducing p21 expression

Yun Zhong, Lluis Lopez-Barcons, Missak Haigentz, Yi-He Ling, Roman Perez-Soler
Pages: 1573-1579
Published online on: 01 June 2004

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Article

Adjuvant effect of dendritic cells transduced with recombinant vaccinia virus expressing HPV16-E7 is inhibited by co-expression of IL12

Jana Mackova, Luda Kutinova, Petr Hainz, Jitka Krystofova, Vojtech Sroller, Pavel Otahal, Pavel Gabriel, Sarka Nemeckova
Pages: 1581-1588
Published online on: 01 June 2004

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Article

Distinguishing key biological pathways between primary breast cancers and their lymph node metastases by gene function-based clustering analysis

Harri Lähdesmäki, Xishan Hao, Baocun Sun, Limei Hu, Olli Yli-Harja, Ilya Shmulevich, Wei Zhang
Pages: 1589-1596
Published online on: 01 June 2004

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Article

Wild-type p16INK4a suppresses cell growth, telomerase activity and DNA repair in human breast cancer MCF-7 cells

Jianming Duan, Zhong Chen, Pinghu Liu, Zongyu Zhang, Tanjun Tong
Pages: 1597-1605
Published online on: 01 June 2004

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Article

Assessment of the antiinvasive potential of the anthracycline aclacinomycin (Aclarubicin®) in a human fibrosarcoma cell line

Salima Addadi-Rebbah, Stephane Poitevin, Nicolas Fourre, Myriam Polette, Roselyne Garnotel, Pierre Jeannesson
Pages: 1607-1615
Published online on: 01 June 2004

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Article

Identification and characterization of ASXL3 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 1617-1622
Published online on: 01 June 2004

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Article

Identification and characterization of JMJD2 family genes in silico

Masuko Katoh, Masaru Katoh
Pages: 1623-1628
Published online on: 01 June 2004

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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