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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2017 Volume 51 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Molecular profiling of locally-advanced rectal adenocarcinoma using microRNA expression (Review)

Cory Pettit, Steve Walston, Patrick Wald, Amy Webb, Terence M. Williams
Pages: 393-404
Published online on: 14 June 2017

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Review Open Access

World Health Organization, radiofrequency radiation and health - a hard nut to crack (Review)

Lennart Hardell
Pages: 405-413
Published online on: 21 June 2017

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Article Open Access

The ginsenoside metabolite compound K inhibits growth, migration and stemness of glioblastoma cells

Sanghun Lee, Min Cheol Kwon, Jun-Pil Jang, Jae Kyung Sohng, Hye Jin Jung
Pages: 414-424
Published online on: 23 June 2017

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Article Open Access

Bevacizumab counteracts VEGF-dependent resistance to erlotinib in an EGFR-mutated NSCLC xenograft model

Chinami Masuda, Mieko Yanagisawa, Keigo Yorozu, Mitsue Kurasawa, Koh Furugaki, Nobuyuki Ishikura, Toshiki Iwai, Masamichi Sugimoto, Kaname Yamamoto
Pages: 425-434
Published online on: 08 June 2017

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Article Open Access

Loss of miR-449a-caused PrLZ overexpression promotes prostate cancer metastasis

Wei Chen, Yi Liu, Hongde Chen, Hao Ning, Kejia Ding
Pages: 435-444
Published online on: 12 June 2017

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Article Open Access

Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells

Huijun Zeng, Ningbo Xu, Yanting Liu, Boyang Liu, Zhao Yang, Zhao Fu, Changlin Lian, Hongbo Guo
Pages: 445-455
Published online on: 07 June 2017

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Article Open Access

Fli-1 overexpression in erythroleukemic cells promotes erythroid de-differentiation while Spi-1/PU.1 exerts the opposite effect

Laura M. Vecchiarelli-Federico, Tangjingjun Liu, Yao Yao, Yuanyuan Gao, Yanmei Li, You-Jun Li, Yaacov Ben-David
Pages: 456-466
Published online on: 02 June 2017

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Article Open Access

Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells

Xue Wang, Jiaojiao Deng, Jinxia Yuan, Xin Tang, Yuelong Wang, Haifeng Chen, Yi Liu, Liangxue Zhou
Pages: 467-477
Published online on: 08 June 2017

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Article Open Access

Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo

Jianbao Zheng, Sai He, Jie Qi, Xiaolong Wang, Junhui Yu, Yunhua Wu, Qi Gao, Kai Wang, Xuejun Sun
Pages: 478-488
Published online on: 13 June 2017

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Article Open Access

Increased PTPRA expression leads to poor prognosis through c-Src activation and G1 phase progression in squamous cell lung cancer

Zhidong Gu, Xuqian Fang, Chang Li, Changqiang Chen, Guangshu Liang, Xinming Zheng, Qishi Fan
Pages: 489-497
Published online on: 23 June 2017

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Article

In vivo evaluation of tumour acidosis for assessing the early metabolic response and onset of resistance to dichloroacetate by using magnetic resonance pH imaging

Annasofia Anemone, Lorena Consolino, Laura Conti, Francesca Reineri, Federica Cavallo, Silvio Aime, Dario Livio Longo
Pages: 498-506
Published online on: 07 June 2017

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Article

ElncRNA1, a long non-coding RNA that is transcriptionally induced by oestrogen, promotes epithelial ovarian cancer cell proliferation

Jun-Jun Qiu, Xiao-Dan Zhang, Xiao-Yan Tang, Ting-Ting Zheng, Ying Zhang, Ke-Qin Hua
Pages: 507-514
Published online on: 07 June 2017

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Article

Epithelial-mesenchymal transition and cancer stem cell-like phenotype induced by Twist1 contribute to acquired resistance to irinotecan in colon cancer

Yong Yang, Guoxin Wang, Dajian Zhu, Yanfeng Huang, Yong Luo, Pengfei Su, Xiaowu Chen, Qian Wang
Pages: 515-524
Published online on: 14 June 2017

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Article

Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer

Xiao Fang, Tenghui Hu, Hua Yin, Junjun Yang, Weian Tang, Siqi Hu, Xingxiang Xu
Pages: 525-532
Published online on: 14 June 2017

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Article

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

Antonella Cusimano, Daniele Balasus, Antonina Azzolina, Giuseppa Augello, Maria R. Emma, Caterina Di Sano, Roberto Gramignoli, Stephen C. Strom, James A. McCubrey, Giuseppe Montalto, Melchiorre Cervello
Pages: 533-544
Published online on: 21 June 2017

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Article

The Wnt inhibitor LGK-974 enhances radiosensitivity of HepG2 cells by modulating Nrf2 signaling

Dan Tian, Ying Shi, Dexi Chen, Qiang Liu, Feiyue Fan
Pages: 545-554
Published online on: 14 June 2017

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Article

Inhibition of STAT3 signaling pathway by ursolic acid suppresses growth of hepatocellular carcinoma

Tianshu Liu, Haiyan Ma, Wei Shi, Jialin Duan, Yina Wang, Cuntai Zhang, Chenglong Li, Jiayuh Lin, Sheng Li, Jiagao Lv, Li Lin
Pages: 555-562
Published online on: 08 June 2017

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Article

APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells

Jing Wang, Dajun Yang, Qiuyun Luo, Miaozhen Qiu, Lin Zhang, Baoxia Li, Haibo Chen, Hanjie Yi, Xianglei Yan, Shuxia Li, Jian Sun
Pages: 563-572
Published online on: 06 June 2017

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Article

Hsp70 acetylation prevents caspase-dependent/independent apoptosis and autophagic cell death in cancer cells

Yoo Hoi Park, Ji Hae Seo, Ji-Hyeon Park, Hye Shin Lee, Kyu-Won Kim
Pages: 573-578
Published online on: 12 June 2017

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Article

Nuclear expression of Y box binding-1 is important for resistance to chemotherapy including gemcitabine in TP53-mutated bladder cancer

Takahisa Yamashita, Morihiro Higashi, Shuji Momose, Makoto Morozumi, Jun-Ichi Tamaru
Pages: 579-586
Published online on: 07 June 2017

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Article

Synergistic cytotoxic effects of arsenite and tetrandrine in human breast cancer cell line MCF-7

Mingjiang Yao, Bo Yuan, Xiao Wang, Ai Sato, Kana Sakuma, Kurumi Kaneko, Hana Komuro, Ayane Okazaki, Hideki Hayashi, Hiroo Toyoda, Xiaohua Pei, Xiaomei Hu, Toshihiko Hirano, Norio Takagi
Pages: 587-598
Published online on: 23 June 2017

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Article

HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC

Tiia Honkanen, Emmi Wilenius, Peppi Koivunen, Jussi P. Koivunen
Pages: 599-606
Published online on: 21 June 2017

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Article

Induction of apoptosis by Galectin-9 in liver metastatic cancer cells: In vitro study

Tomoko Tadokoro, Shintaro Fujihara, Taiga Chiyo, Kyoko Oura, Eri Samukawa, Yoshimi Yamana, Koji Fujita, Shima Mimura, Teppei Sakamoto, Takako Nomura, Joji Tani, Hirohito Yoneyama, Asahiro Morishita, Takashi Himoto, Hisakazu Iwama, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 607-614
Published online on: 23 June 2017

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Article

18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration

Saisai Wang, Yong Shen, Runfeng Qiu, Zhiliang Chen, Zhehang Chen, Wenbin Chen
Pages: 615-624
Published online on: 27 June 2017

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Article

Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma

Hiroyuki Takada, Soichiro Ibaragi, Takanori Eguchi, Tatsuo Okui, Kyoichi Obata, Masanori Masui, Ayaka Morisawa, Kiyofumi Takabatake, Hotaka Kawai, Norie Yoshioka, Nur Mohammad Monsur Hassan, Tsuyoshi Shimo, Guo-Fu Hu, Hitoshi Nagatsuka, Akira Sasaki
Pages: 625-632
Published online on: 21 June 2017

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Article

Butein inhibits NF-κB, AP-1 and Akt activation in adult T-cell leukemia/lymphoma

Chie Ishikawa, Masachika Senba, Naoki Mori
Pages: 633-643
Published online on: 02 June 2017

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Article

Autophagy plays an important role in stemness mediation and the novel dual function of EIG121 in both autophagy and stemness regulation of endometrial carcinoma JEC cells

Xiaomin Ran, Ping Zhou, Keqiang Zhang
Pages: 644-656
Published online on: 21 June 2017

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Article

HNF1A‑AS1 promotes growth and metastasis of esophageal squamous cell carcinoma by sponging miR‑214 to upregulate the expression of SOX-4 Retraction in /10.3892/ijo.2021.5170

Guannan Wang, Wugan Zhao, Xianzheng Gao, Dandan Zhang, Ye Li, Yanping Zhang, Wencai Li
Pages: 657-667
Published online on: 08 June 2017

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Article

Nestin-positive microvessel density is an independent prognostic factor in breast cancer

Aleksandra Nowak, Jedrzej Grzegrzolka, Maria Paprocka, Aleksandra Piotrowska, Janusz Rys, Rafal Matkowski, Piotr Dziegiel
Pages: 668-676
Published online on: 26 June 2017

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Article

Luteolin inhibits angiogenesis by blocking Gas6/Axl signaling pathway

Xiaobo Li, Minfeng Chen, Xueping Lei, Maohua Huang, Wencai Ye, Rijia Zhang, Dongmei Zhang
Pages: 677-685
Published online on: 13 June 2017

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Article

Circulating regulatory T cell subsets predict overall survival of patients with unresectable pancreatic cancer

Chen Liu, He Cheng, Guopei Luo, Yu Lu, Kaizhou Jin, Meng Guo, Quanxing Ni, Xianjun Yu
Pages: 686-694
Published online on: 07 June 2017

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Article

Intra-arterially infused carbon dioxide-saturated solution for sensitizing the anticancer effect of cisplatin in a rabbit VX2 liver tumor model

Naoto Katayama, Koji Sugimoto, Takuya Okada, Takeshi Ueha, Yoshitada Sakai, Hideo Akiyoshi, Keiichiro Mie, Eisuke Ueshima, Keitaro Sofue, Yutaka Koide, Ryuichiro Tani, Tomoyuki Gentsu, Masato Yamaguchi
Pages: 695-701
Published online on: 26 June 2017

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Article

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors

Angela Armento, Elena I. Ilina, Tony Kaoma, Arnaud Muller, Laurent Vallar, Simone P. Niclou, Marcel A. Krüger, Michel Mittelbronn, Ulrike Naumann
Pages: 702-714
Published online on: 21 June 2017

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Article

HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model

Dong Hwan Kim, Bokyung Sung, Jin-Ah Kim, Yong Jung Kang, Seong Yeon Hwang, Na-Lam Hwang, Hongsuk Suh, Yung Hyun Choi, Eunok Im, Hae Young Chung, Nam Deuk Kim
Pages: 715-723
Published online on: 27 June 2017

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Article

Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway

Yukie Takahashi, Chizu Tanikawa, Takafumi Miyamoto, Makoto Hirata, Guanxiong Wang, Koji Ueda, Tsunehiko Komatsu, Koichi Matsuda
Pages: 724-736
Published online on: 28 June 2017

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Article

Overexpression of the erythropoietin receptor in RAMA 37 breast cancer cells alters cell growth and sensitivity to tamoxifen

Lenka Ilkovičová, Nina Trošt, Erika Szentpéteriová, Peter Solár, Radovan Komel, Nataša Debeljak
Pages: 737-746
Published online on: 28 June 2017

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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