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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2017 Volume 51 Issue 6

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Comprehensive analysis of circRNA expression profiles in humans by RAISE

Lin Li, Yong-Chang Zheng, Masood Ur Rehman Kayani, Wen Xu, Guan-Qun Wang, Pei Sun, Ning Ao, Li-Na Zhang, Zhao-Qi Gu, Liang-Cai Wu, Hai-Tao Zhao
Pages: 1625-1638
Published online on: 16 October 2017

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Article Open Access

E2F1 silencing inhibits migration and invasion of osteosarcoma cells via regulating DDR1 expression

Zhaofeng Wang, Xianjie Sun, Yi Bao, Juanfen Mo, Hengchao Du, Jichao Hu, Xingen Zhang
Pages: 1639-1650
Published online on: 16 October 2017

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Article Open Access

Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays

Angela Caunii, Camelia Oprean, Mirabela Cristea, Alexandra Ivan, Corina Danciu, Calin Tatu, Virgil Paunescu, Daniela Marti, George Tzanakakis, Demetrios A. Spandidos, Aristides Tsatsakis, Razvan Susan, Codruta Soica, Stefana Avram, Cristina Dehelean
Pages: 1651-1660
Published online on: 16 October 2017

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Article Open Access

Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer

Rakesh Dachineni, D. Ramesh Kumar, Eduardo Callegari, Siddharth S. Kesharwani, Ranjini Sankaranarayanan, Teresa Seefeldt, Hemachand Tummala, G. Jayarama Bhat
Pages: 1661-1673
Published online on: 19 October 2017

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Article Open Access

Angiotensin receptor blocker telmisartan inhibits cell proliferation and tumor growth of cholangiocarcinoma through cell cycle arrest

Eri Samukawa, Shintaro Fujihara, Kyoko Oura, Hisakazu Iwama, Yoshimi Yamana, Tomoko Tadokoro, Taiga Chiyo, Kiyoyuki Kobayashi, Asahiro Morishita, Mai Nakahara, Hideki Kobara, Hirohito Mori, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki
Pages: 1674-1684
Published online on: 23 October 2017

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Article Open Access

5,6,7,3',4',5'-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting cell cycle

Natasha Borah, Shimara Gunawardana, Haydee Torres, Susan McDonnell, Severine Van Slambrouck
Pages: 1685-1693
Published online on: 13 October 2017

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Article Open Access

SRC3 expressed in BMSCs promotes growth and migration of multiple myeloma cells by regulating the expression of Cx43

Jie Jin, Tao Wang, Yu Wang, Shidi Chen, Zheng Li, Xiang Li, Jiazhen Zhang, Jin Wang
Pages: 1694-1704
Published online on: 20 October 2017

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Article Open Access

Long non‑coding RNA HOTTIP promotes hepatocellular carcinoma tumorigenesis and development: A comprehensive investigation based on bioinformatics, qRT‑PCR and meta‑analysis of 393 cases

Yu Zhang, Jia-Cheng Huang, Kai-Teng Cai, Xi-Bing Yu, You-Rong Chen, Wen-Ya Pan, Ze-Liang He, Jun Lv, Zhen-Bo Feng, Gang Chen
Pages: 1705-1721
Published online on: 16 October 2017

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Article Open Access

Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis

Tianyu He, Lufei Zhang, Yang Kong, Yu Huang, Yuan Zhang, Dongkai Zhou, Xiaohu Zhou, Yingcai Yan, Linshi Zhang, Sinan Lu, Jiarong Zhou, Weilin Wang
Pages: 1722-1730
Published online on: 23 October 2017

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Article

Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients

Kazuma Noguchi, Keiko Wakai, Tohru Kiyono, Mutsuki Kawabe, Kyohei Yoshikawa, Tomoko Hashimoto-Tamaoki, Hiromitsu Kishimoto, Yoshiro Nakano
Pages: 1731-1738
Published online on: 09 October 2017

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Article

Antitumoral effect of arsenic compound, sodium metaarsenite (KML001), on multiple myeloma cells

Seo Ju Kim, Eun Shil Kim, Sujong Kim, Jieun Uhm, Young Woong Won, Byeong Bae Park, Jung Hye Choi, Young Yiul Lee
Pages: 1739-1746
Published online on: 16 October 2017

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Article

Differential contribution of tissue factor and Factor XII to thrombin generation triggered by breast and pancreatic cancer cells

Aurélie Rousseau, Annette K. Larsen, Patrick Van Dreden, Michele Sabbah, Ismail Elalamy, Grigoris T. Gerotziafas
Pages: 1747-1756
Published online on: 20 October 2017

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Article

miR-608 regulates apoptosis in human lung adenocarcinoma via regulation of AKT2

Norahayu Othman, Noor Hasima Nagoor
Pages: 1757-1764
Published online on: 23 October 2017

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Article

Evaluation of a radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression

Maria Rosestedt, Ken G. Andersson, Bogdan Mitran, Sara S. Rinne, Vladimir Tolmachev, John Löfblom, Anna Orlova, Stefan Ståhl
Pages: 1765-1774
Published online on: 11 October 2017

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Article

BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage

Chunhui Dou, Chunyan Fang, Yan Zhao, Xiaoyan Fu, Yufei Zhang, Dongqi Zhu, Huina Wu, Huijie Liu, Jian Zhang, Wenfang Xu, Zhijun Liu, Hongyan Wang, Daqi Li, Xuejian Wang
Pages: 1775-1784
Published online on: 16 October 2017

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Article

Effects of baicalein on proliferation, apoptosis, migration and invasion of Ewing's sarcoma cells

Conglin Ye, Xiaolong Yu, Jin Zeng, Min Dai, Bin Zhang
Pages: 1785-1792
Published online on: 10 October 2017

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Article

Procoagulant microparticles derived from cancer cells have determinant role in the hypercoagulable state associated with cancer

Aurélie Rousseau, Patrick Van Dreden, Amir Khaterchi, Annette K. Larsen, Ismail Elalamy, Grigoris T. Gerotziafas
Pages: 1793-1800
Published online on: 20 October 2017

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Article

Lippia origanoides extract induces cell cycle arrest and apoptosis and suppresses NF-κB signaling in triple-negative breast cancer cells

Vishak Raman, Jorge Luis Fuentes Lorenzo, Elena E. Stashenko, Morris Levy, Maria M. Levy, Ignacio G. Camarillo
Pages: 1801-1808
Published online on: 19 October 2017

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Article

Parthenolide suppresses hypoxia-inducible factor-1α signaling and hypoxia induced epithelial-mesenchymal transition in colorectal cancer

Se Lim Kim, Young Ran Park, Soo Teik Lee, Sang-Wook Kim
Pages: 1809-1820
Published online on: 18 October 2017

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Article

GSK-3β inhibitor 6-bromo-indirubin-3'-oxime promotes both adhesive activity and drug resistance in colorectal cancer cells

Kunping Liu, Jinbang Li, Xuefang Wu, Meixiang Chen, Feng Luo, Jun Li
Pages: 1821-1830
Published online on: 16 October 2017

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Article

Actein induces apoptosis in leukemia cells through suppressing RhoA/ROCK1 signaling pathway

Wen-Di Zhou, Xiang Wang, Xing-Zhen Sun, Jian Hu, Rong-Rong Zhang, Ze Hong
Pages: 1831-1841
Published online on: 10 October 2017

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Article

MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura
Pages: 1842-1850
Published online on: 12 October 2017

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Article

Simvastatin inhibits the expression of stemness‑related genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton

Rosarita Tatè, Enrica Zona, Rosanna De Cicco, Veronica Trotta, Maria Urciuoli, Alessandro Morelli, Salvatore Baiano, Rosa Carnuccio, Maria Pia Fuggetta, Franco Morelli
Pages: 1851-1859
Published online on: 13 October 2017

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Article

Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines

Ya-Mei Wang, Meng-Li Gu, Fan-Sheng Meng, Wen-Rui Jiao, Xin-Xin Zhou, Hang-Ping Yao, Feng Ji
Pages: 1860-1868
Published online on: 23 October 2017

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Article

Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas

Petar Ozretić, Diana Trnski, Vesna Musani, Ivana Maurac, Držislav Kalafatić, Slavko Orešković, Sonja Levanat, Maja Sabol
Pages: 1869-1877
Published online on: 12 October 2017

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Article

Synergistic effects of baicalein with gemcitabine or docetaxel on the proliferation, migration and apoptosis of pancreatic cancer cells

Pan Liu, Jiarui Feng, Meng Sun, Wen Yuan, Ruijing Xiao, Jie Xiong, Xiaoxin Huang, Meng Xiong, Wu Chen, Xin Yu, Qian Sun, Xiaojie Zhao, Qiuping Zhang, Liang Shao
Pages: 1878-1886
Published online on: 11 October 2017

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Article

Altered expression of different GalNAc‑transferases is associated with disease progression and poor prognosis in women with high-grade serous ovarian cancer

Razan Sheta, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Ion Popa, Dimcho Bachvarov
Pages: 1887-1897
Published online on: 09 October 2017

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Article

Mdig suppresses epithelial-mesenchymal transition and inhibits the invasion and metastasis of non‑small cell lung cancer via regulating GSK-3β/β-catenin signaling

Feng Geng, Zhanshi Jiang, Xiaogang Song, Haomin Zhou, Hongwen Zhao
Pages: 1898-1908
Published online on: 12 October 2017

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Article

Antiproliferative activity of di-2-pyridylhydrazone dithiocarbamate acetate partly involved in p53 mediated apoptosis and autophagy

Tingting Wang, Youxun Liu, Yun Fu, Tengfei Huang, Yun Yang, Shaoshan Li, Changzheng Li
Pages: 1909-1919
Published online on: 10 October 2017

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Article

SPARC suppresses lymph node metastasis by regulating the expression of VEGFs in ovarian carcinoma

Fenghui Peng, Yanping Zhong, Yunfeng Liu, Yueming Zhang, Yihong Xie, Yingxin Lu, Xinyin Zhang, Danrong Li
Pages: 1920-1928
Published online on: 19 October 2017

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Article

Functional analysis of HOXA10 and HOXB4 in human medulloblastoma cell lines

Ricardo Bonfim-Silva, Fernanda Ursoli Ferreira Melo, Carolina Hassibe Thomé, Kuruvilla Joseph Abraham, Fábio Augusto Labre De Souza, Fernando Silva Ramalho, Hélio Rubens Machado, Ricardo Santos De Oliveira, Angelo A. Cardoso, Dimas Tadeu Covas, Aparecida Maria Fontes
Pages: 1929-1940
Published online on: 10 October 2017

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Article

BANCR contributes to the growth and invasion of melanoma by functioning as a competing endogenous RNA to upregulate Notch2 expression by sponging miR‑204

Bingjie Cai, Yunpeng Zheng, Shanshan Ma, Qu Xing, Xinxin Wang, Bo Yang, Guangwen Yin, Fangxia Guan
Pages: 1941-1951
Published online on: 23 October 2017

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Journal Cover
July-2026 Volume 69 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Emerging agents that target signaling pathways in cancer fibroblast cells (Review)

Yan Wan, Xiang-Qing Liu, Dong Liu, Ke-Di Li, Dan-Dan Zhang
Article Number: 87
Published online on: 03 June 2026

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Review Open Access

Metabolic remodeling by circular RNAs in gastric tumorigenesis: From mechanisms to biomarker discovery (Review)

Xinyi Liang, Tianlin Wang, Jiale Ma, Shuangmei Zhao, Wang Gao, Yan Yang, Xinyuan Zhang, Huizhen Li
Article Number: 86
Published online on: 03 June 2026

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Correction Open Access

[Corrigendum] Cell density‑dependent regulation of p73 in breast cancer cells

Chaitali Tophkhane, Shihe Yang, Zhizhuang Joe Zhao, Xiaohe Yang
Article Number: 85
Published online on: 25 May 2026

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Review Open Access

P2X7 receptor: An emerging therapeutic target in acute myeloid leukemia (Review)

Yunqing Liu, Hongfan Xue, Hanheng Mai, Tan Sang, Zonghong Li, Na Wang, Lili Feng
Article Number: 84
Published online on: 22 May 2026

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Expression of Concern Open Access

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects

D. Carlisi, B. Vassallo, M. Lauricella, S.  Emanuele, A. D'anneo, E. Di Leonardo, P. Di Fazio, R.  Vento, G.  Tesoriere
Article Number: 83
Published online on: 20 May 2026

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Article Open Access

Integrin beta 4 promotes colorectal cancer progression by upregulating Ezrin and activating the Wnt/β‑catenin signaling pathway

Jing Wang, Yi Si, Mingda Xuan, Shuangshuang Han, Kunyi Liu, Jiao Jiao, Xiaoyan Men, Hongfei Li, Jia Wang, Ting Liu, Weifang Yu
Article Number: 82
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells

Pin-Hao Ko, Govinda Lenka, Yu-An Chen, Eric Y. Chuang, Mong-Hsun Tsai, Yuh-Pyng Sher, Liang-Chuan Lai
Article Number: 81
Published online on: 18 May 2026

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Review Open Access

snoRNAs and their derived sdRNAs: Emerging regulators, biomarkers, and therapeutic targets in human cancers (Review)

Jiahui Mao, Hao Lin, Feng Gu, Zhaoji Pan
Article Number: 80
Published online on: 15 May 2026

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Review Open Access

Deubiquitinating enzymes in cervical cancer: Molecular mechanisms and therapeutic implications (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 79
Published online on: 14 May 2026

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Article Open Access

BMP4 derived from human gastrointestinal carcinoma cells impairs myogenic differentiation: A possible in vitro mechanism of cancer‑induced cachexia

Kazuki Higure, Yoshihiko Kitajima, Naoya Kimura, Shota Ikeda, Shohei Matsufuji, Tomokazu Tanaka, Hirokazu Noshiro
Article Number: 78
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Radiation‑inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Venkateswara Rao Gogineni, Arun Kumar Nalla, Reshu Gupta, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Article Number: 77
Published online on: 11 May 2026

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Review Open Access

Circulating proteins as biomarkers of response to cancer immunotherapy (Review)

Celeste Pinard, Angeline Ginzac, Catherine Abrial, Xavier Durando, Nina Radosevic‑Robin
Article Number: 76
Published online on: 06 May 2026

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Correction Open Access

[Corrigendum] Tumor necrosis factor‑α triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial‑ and non‑mitochondrial‑dependent pathways

Denis Selimovic, Renate   U. Wahl, Emmanuelle Ruiz, Rizwan Aslam, Thomas   W. Flanagan, Sofie-Yasmin Hassan, Simeon Santourlidis, Youssef Haikel, Paul Friedlander, Mosaad Megahed, Emad Kandil, Mohamed Hassan
Article Number: 75
Published online on: 27 April 2026

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Journal Cover
August-2026 Volume 69 Issue 2

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Expression of Concern Open Access

[Expression of Concern] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex  

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 95
Published online on: 24 June 2026

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Review

Radiotherapy resistance in glioblastoma: Mechanistic insights and novel therapeutic approaches (Review)

Dengtian Zhang, Yiming Zhang, Fen Liu, Cong Zhang, Shulong Jiang
Article Number: 94
Published online on: 24 June 2026

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Review Open Access

Understanding the epigenetic regulation of lactylation and aberrant lactate metabolism in cancer: From mechanisms to therapeutic strategies (Review)

Xiaoli Zheng, Jiayi Zhang, Chengwei Mao, Yingxue Si, Chengcheng Chi, Tingting Xiong, Mengjie Gu, Chunyan Zhang, Haiying Han, Yangling Li, Chong Zhang
Article Number: 93
Published online on: 22 June 2026

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Article Open Access

Stress‑induced catecholamines attenuate sorafenib efficacy by inhibiting ferroptosis in β2‑adrenergic receptor positive renal cell carcinoma

Masaki Ushijima, Sei Naito, Hiromi Ito, Takafumi Narisawa, Osamu Ichiyanagi, Hidenori Kanno, Hiroki Fukuhara, Yuki Takai, Mayu Yagi, Atushi Yamagishi, Hayato Nishida, Yutaro Obara, Norihiko Tsuchiya
Article Number: 92
Published online on: 22 June 2026

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Retraction Open Access

[Retracted] Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase‑2  

Tripti Singh, Santosh K. Katiyar
Article Number: 91
Published online on: 22 June 2026

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Unraveling the roles of fibroblast activation protein‑positive cancer‑associated fibroblasts in cancer: From mechanisms to therapy (Review)

Zhixin Tao, Zhuan Zhou, Yong Wu, Jinwei Hu
Article Number: 90
Published online on: 18 June 2026

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Retraction Open Access

[Retracted] Downregulation of uPA/uPAR inhibits intermittent hypoxia‑induced epithelial‑mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells

Reshu Gupta, Chandramu Chetty, Praveen Bhoopathi, Sajani Lakka, Sanjeeva Mohanam, Asti S. Rao, Dzung H. Dinh
Article Number: 89
Published online on: 08 June 2026

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Review Open Access

Targeted therapy in BRAF‑mutant melanoma: Advances and challenges (Review)

Lu Zhang, Dongliang Shen, Jianguo Feng, Liling Tang
Article Number: 88
Published online on: 04 June 2026

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