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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2017 Volume 51 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Comprehensive analysis of circRNA expression profiles in humans by RAISE

Lin Li, Yong-Chang Zheng, Masood Ur Rehman Kayani, Wen Xu, Guan-Qun Wang, Pei Sun, Ning Ao, Li-Na Zhang, Zhao-Qi Gu, Liang-Cai Wu, Hai-Tao Zhao
Pages: 1625-1638
Published online on: 16 October 2017

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Article Open Access

E2F1 silencing inhibits migration and invasion of osteosarcoma cells via regulating DDR1 expression

Zhaofeng Wang, Xianjie Sun, Yi Bao, Juanfen Mo, Hengchao Du, Jichao Hu, Xingen Zhang
Pages: 1639-1650
Published online on: 16 October 2017

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Article Open Access

Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays

Angela Caunii, Camelia Oprean, Mirabela Cristea, Alexandra Ivan, Corina Danciu, Calin Tatu, Virgil Paunescu, Daniela Marti, George Tzanakakis, Demetrios A. Spandidos, Aristides Tsatsakis, Razvan Susan, Codruta Soica, Stefana Avram, Cristina Dehelean
Pages: 1651-1660
Published online on: 16 October 2017

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Article Open Access

Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer

Rakesh Dachineni, D. Ramesh Kumar, Eduardo Callegari, Siddharth S. Kesharwani, Ranjini Sankaranarayanan, Teresa Seefeldt, Hemachand Tummala, G. Jayarama Bhat
Pages: 1661-1673
Published online on: 19 October 2017

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Article Open Access

Angiotensin receptor blocker telmisartan inhibits cell proliferation and tumor growth of cholangiocarcinoma through cell cycle arrest

Eri Samukawa, Shintaro Fujihara, Kyoko Oura, Hisakazu Iwama, Yoshimi Yamana, Tomoko Tadokoro, Taiga Chiyo, Kiyoyuki Kobayashi, Asahiro Morishita, Mai Nakahara, Hideki Kobara, Hirohito Mori, Keiichi Okano, Yasuyuki Suzuki, Takashi Himoto, Tsutomu Masaki
Pages: 1674-1684
Published online on: 23 October 2017

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Article Open Access

5,6,7,3',4',5'-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting cell cycle

Natasha Borah, Shimara Gunawardana, Haydee Torres, Susan McDonnell, Severine Van Slambrouck
Pages: 1685-1693
Published online on: 13 October 2017

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Article Open Access

SRC3 expressed in BMSCs promotes growth and migration of multiple myeloma cells by regulating the expression of Cx43

Jie Jin, Tao Wang, Yu Wang, Shidi Chen, Zheng Li, Xiang Li, Jiazhen Zhang, Jin Wang
Pages: 1694-1704
Published online on: 20 October 2017

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Article Open Access

Long non‑coding RNA HOTTIP promotes hepatocellular carcinoma tumorigenesis and development: A comprehensive investigation based on bioinformatics, qRT‑PCR and meta‑analysis of 393 cases

Yu Zhang, Jia-Cheng Huang, Kai-Teng Cai, Xi-Bing Yu, You-Rong Chen, Wen-Ya Pan, Ze-Liang He, Jun Lv, Zhen-Bo Feng, Gang Chen
Pages: 1705-1721
Published online on: 16 October 2017

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Article Open Access

Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis

Tianyu He, Lufei Zhang, Yang Kong, Yu Huang, Yuan Zhang, Dongkai Zhou, Xiaohu Zhou, Yingcai Yan, Linshi Zhang, Sinan Lu, Jiarong Zhou, Weilin Wang
Pages: 1722-1730
Published online on: 23 October 2017

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Article

Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients

Kazuma Noguchi, Keiko Wakai, Tohru Kiyono, Mutsuki Kawabe, Kyohei Yoshikawa, Tomoko Hashimoto-Tamaoki, Hiromitsu Kishimoto, Yoshiro Nakano
Pages: 1731-1738
Published online on: 09 October 2017

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Article

Antitumoral effect of arsenic compound, sodium metaarsenite (KML001), on multiple myeloma cells

Seo Ju Kim, Eun Shil Kim, Sujong Kim, Jieun Uhm, Young Woong Won, Byeong Bae Park, Jung Hye Choi, Young Yiul Lee
Pages: 1739-1746
Published online on: 16 October 2017

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Article

Differential contribution of tissue factor and Factor XII to thrombin generation triggered by breast and pancreatic cancer cells

Aurélie Rousseau, Annette K. Larsen, Patrick Van Dreden, Michele Sabbah, Ismail Elalamy, Grigoris T. Gerotziafas
Pages: 1747-1756
Published online on: 20 October 2017

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Article

miR-608 regulates apoptosis in human lung adenocarcinoma via regulation of AKT2

Norahayu Othman, Noor Hasima Nagoor
Pages: 1757-1764
Published online on: 23 October 2017

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Article

Evaluation of a radiocobalt-labelled affibody molecule for imaging of human epidermal growth factor receptor 3 expression

Maria Rosestedt, Ken G. Andersson, Bogdan Mitran, Sara S. Rinne, Vladimir Tolmachev, John Löfblom, Anna Orlova, Stefan Ståhl
Pages: 1765-1774
Published online on: 11 October 2017

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Article

BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage

Chunhui Dou, Chunyan Fang, Yan Zhao, Xiaoyan Fu, Yufei Zhang, Dongqi Zhu, Huina Wu, Huijie Liu, Jian Zhang, Wenfang Xu, Zhijun Liu, Hongyan Wang, Daqi Li, Xuejian Wang
Pages: 1775-1784
Published online on: 16 October 2017

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Article

Effects of baicalein on proliferation, apoptosis, migration and invasion of Ewing's sarcoma cells

Conglin Ye, Xiaolong Yu, Jin Zeng, Min Dai, Bin Zhang
Pages: 1785-1792
Published online on: 10 October 2017

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Article

Procoagulant microparticles derived from cancer cells have determinant role in the hypercoagulable state associated with cancer

Aurélie Rousseau, Patrick Van Dreden, Amir Khaterchi, Annette K. Larsen, Ismail Elalamy, Grigoris T. Gerotziafas
Pages: 1793-1800
Published online on: 20 October 2017

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Article

Lippia origanoides extract induces cell cycle arrest and apoptosis and suppresses NF-κB signaling in triple-negative breast cancer cells

Vishak Raman, Jorge Luis Fuentes Lorenzo, Elena E. Stashenko, Morris Levy, Maria M. Levy, Ignacio G. Camarillo
Pages: 1801-1808
Published online on: 19 October 2017

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Article

Parthenolide suppresses hypoxia-inducible factor-1α signaling and hypoxia induced epithelial-mesenchymal transition in colorectal cancer

Se Lim Kim, Young Ran Park, Soo Teik Lee, Sang-Wook Kim
Pages: 1809-1820
Published online on: 18 October 2017

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Article

GSK-3β inhibitor 6-bromo-indirubin-3'-oxime promotes both adhesive activity and drug resistance in colorectal cancer cells

Kunping Liu, Jinbang Li, Xuefang Wu, Meixiang Chen, Feng Luo, Jun Li
Pages: 1821-1830
Published online on: 16 October 2017

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Article

Actein induces apoptosis in leukemia cells through suppressing RhoA/ROCK1 signaling pathway

Wen-Di Zhou, Xiang Wang, Xing-Zhen Sun, Jian Hu, Rong-Rong Zhang, Ze Hong
Pages: 1831-1841
Published online on: 10 October 2017

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Article

MicroRNA-20b promotes cell proliferation via targeting of TGF-β receptor II and upregulates MYC expression in Ewing's sarcoma cells

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura
Pages: 1842-1850
Published online on: 12 October 2017

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Article

Simvastatin inhibits the expression of stemness‑related genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton

Rosarita Tatè, Enrica Zona, Rosanna De Cicco, Veronica Trotta, Maria Urciuoli, Alessandro Morelli, Salvatore Baiano, Rosa Carnuccio, Maria Pia Fuggetta, Franco Morelli
Pages: 1851-1859
Published online on: 13 October 2017

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Article

Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines

Ya-Mei Wang, Meng-Li Gu, Fan-Sheng Meng, Wen-Rui Jiao, Xin-Xin Zhou, Hang-Ping Yao, Feng Ji
Pages: 1860-1868
Published online on: 23 October 2017

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Article

Non-canonical Hedgehog signaling activation in ovarian borderline tumors and ovarian carcinomas

Petar Ozretić, Diana Trnski, Vesna Musani, Ivana Maurac, Držislav Kalafatić, Slavko Orešković, Sonja Levanat, Maja Sabol
Pages: 1869-1877
Published online on: 12 October 2017

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Article

Synergistic effects of baicalein with gemcitabine or docetaxel on the proliferation, migration and apoptosis of pancreatic cancer cells

Pan Liu, Jiarui Feng, Meng Sun, Wen Yuan, Ruijing Xiao, Jie Xiong, Xiaoxin Huang, Meng Xiong, Wu Chen, Xin Yu, Qian Sun, Xiaojie Zhao, Qiuping Zhang, Liang Shao
Pages: 1878-1886
Published online on: 11 October 2017

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Article

Altered expression of different GalNAc‑transferases is associated with disease progression and poor prognosis in women with high-grade serous ovarian cancer

Razan Sheta, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Ion Popa, Dimcho Bachvarov
Pages: 1887-1897
Published online on: 09 October 2017

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Article

Mdig suppresses epithelial-mesenchymal transition and inhibits the invasion and metastasis of non‑small cell lung cancer via regulating GSK-3β/β-catenin signaling

Feng Geng, Zhanshi Jiang, Xiaogang Song, Haomin Zhou, Hongwen Zhao
Pages: 1898-1908
Published online on: 12 October 2017

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Article

Antiproliferative activity of di-2-pyridylhydrazone dithiocarbamate acetate partly involved in p53 mediated apoptosis and autophagy

Tingting Wang, Youxun Liu, Yun Fu, Tengfei Huang, Yun Yang, Shaoshan Li, Changzheng Li
Pages: 1909-1919
Published online on: 10 October 2017

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Article

SPARC suppresses lymph node metastasis by regulating the expression of VEGFs in ovarian carcinoma

Fenghui Peng, Yanping Zhong, Yunfeng Liu, Yueming Zhang, Yihong Xie, Yingxin Lu, Xinyin Zhang, Danrong Li
Pages: 1920-1928
Published online on: 19 October 2017

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Article

Functional analysis of HOXA10 and HOXB4 in human medulloblastoma cell lines

Ricardo Bonfim-Silva, Fernanda Ursoli Ferreira Melo, Carolina Hassibe Thomé, Kuruvilla Joseph Abraham, Fábio Augusto Labre De Souza, Fernando Silva Ramalho, Hélio Rubens Machado, Ricardo Santos De Oliveira, Angelo A. Cardoso, Dimas Tadeu Covas, Aparecida Maria Fontes
Pages: 1929-1940
Published online on: 10 October 2017

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Article

BANCR contributes to the growth and invasion of melanoma by functioning as a competing endogenous RNA to upregulate Notch2 expression by sponging miR‑204

Bingjie Cai, Yunpeng Zheng, Shanshan Ma, Qu Xing, Xinxin Wang, Bo Yang, Guangwen Yin, Fangxia Guan
Pages: 1941-1951
Published online on: 23 October 2017

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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