Journal Articles

Open Access

Neuroendocrine factors: The missing link in non‑melanoma skin cancer (Review)

Mihai Lupu, Ana Caruntu, Constantin Caruntu, Laura Maria Lucia Papagheorghe, Mihaela Adriana Ilie, Vlad Voiculescu, Daniel Boda, Carolina Constantin, Cristiana Tanase, Maria Sifaki, Nikolaos Drakoulis, Charalampos Mamoulakis, George Tzanakakis, Monica Neagu, Demetrios A. Spandidos, Boris N. Izotov, Aristides M. Tsatsakis

Pages: 1327-1340 Published online on: 13 July 2017
Open Access

Glioblastoma entities express subtle differences in molecular composition and response to treatment

Joana Balça-Silva, Diana Matias, Anália Do Carmo, Luiz Gustavo Dubois, Ana Cristina Gonçalves, Henrique Girão, Nathalie Henriques Silva Canedo, Ana Helena Correia, Jorge Marcondes De Souza, Ana Bela Sarmento-Ribeiro, Maria Celeste Lopes, Vivaldo Moura-Neto

Pages: 1341-1352 Published online on: 07 July 2017
Open Access

Upregulation of long non-coding RNA MALAT-1 confers poor prognosis and influences cell proliferation and apoptosis in acute monocytic leukemia

Jin-Long Huang, Wei Liu, Li-Hong Tian, Ting-Ting Chai, Yang Liu, Feng Zhang, Hai-Ying Fu, Hua-Rong Zhou, Jian-Zhen Shen

Pages: 1353-1362 Published online on: 10 July 2017
Open Access

Microarray expression profiles of long non-coding RNAs in germinal center-like diffuse large B-cell lymphoma

Hong-Yu Gao, Bin Wu, Wei Yan, Zi-Mu Gong, Qi Sun, Hui-Han Wang, Wei Yang

Pages: 1363-1372 Published online on: 14 July 2017
Open Access

Anacardic acid induces cell apoptosis of prostatic cancer through autophagy by ER stress/DAPK3/Akt signaling pathway

Jing Tan, Xianzhen Jiang, Guangming Yin, Leye He, Jianye Liu, Zhi Long, Zhiqiang Jiang, Kun Yao

Pages: 1373-1382 Published online on: 20 July 2017
Open Access

MEG3 is a prognostic factor for CRC and promotes chemosensitivity by enhancing oxaliplatin-induced cell apoptosis

Lixia Li, Jian Shang, Yupeng Zhang, Shi Liu, Yanan Peng, Zhou Zhou, Huaqing Pan, Xiaobing Wang, Lipng Chen, Qiu Zhao

Pages: 1383-1392 Published online on: 17 July 2017
Open Access

CCL28 promotes breast cancer growth and metastasis through MAPK-mediated cellular anti-apoptosis and pro-metastasis

Xiao Li Yang, Kai Yi Liu, Feng Juan Lin, Hui Min Shi, Zhou Luo Ou

Pages: 1393-1401 Published online on: 07 July 2017
Open Access

The long non-coding RNA SNHG3 functions as a competing endogenous RNA to promote malignant development of colorectal cancer

Weizhen Huang, Yunming Tian, Shaoting Dong, Yinlian Cha, Jun Li, Xiaohong Guo, Xia Yuan

Pages: 1402-1410 Published online on: 18 July 2017
Open Access

The biological functions and mechanism of miR‑212 in prostate cancer proliferation, migration and invasion via targeting Engrailed-2

Yi Zhou, Zhigang Ji, Weigang Yan, Zhien Zhou, Hanzhong Li

Pages: 1411-1419 Published online on: 12 July 2017
Open Access

Bufalin reverses acquired drug resistance by inhibiting stemness in colorectal cancer cells

Jian Sun, Ke Xu, Yanyan Qiu, Hong Gao, Jianhua Xu, Qingfeng Tang, Peihao Yin

Pages: 1420-1430 Published online on: 17 July 2017
Open Access

Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3

Bingyu Zou, Hailian Wang, Yilong Liu, Ping Qi, Tiantian Lei, Minghan Sun, Yi Wang

Pages: 1431-1441 Published online on: 13 July 2017
Open Access

Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells

Xin Guo, Nan Guo, Jianwen Zhao, Yunlang Cai

Pages: 1442-1450 Published online on: 18 July 2017
Open Access

ALDH1L1 variant rs2276724 and mRNA expression predict post-operative clinical outcomes and are associated with TP53 expression in HBV-related hepatocellular carcinoma

Guangzhi Zhu, Xiwen Liao, Chuangye Han, Xiaoguang Liu, Long Yu, Wei Qin, Sicong Lu, Hao Su, Zhiwei Chen, Zhengtao Liu, Yu Liang, Jianlu Huang, Tingdong Yu, Chengkun Yang, Ketuan Huang, Liming Shang, Xinping Ye, Lequn Li, Xue Qin, Kaiyin Xiao, Minhao Peng, Tao Peng

Pages: 1451-1463 Published online on: 14 July 2017
Open Access

Human chorionic gonadotropin β regulates epithelial-mesenchymal transition and metastasis in human ovarian cancer

Na Liu, Shu-Min Peng, Guang-Xi Zhan, Jing Yu, Wei-Min Wu, Hao Gao, Xiao-Feng Li, Xiao-Qing Guo

Pages: 1464-1472 Published online on: 14 July 2017
Open Access

miR-374 mediates the malignant transformation of gastric cancer-associated mesenchymal stem cells in an experimental rat model

Runbi Ji, Xu Zhang, Hui Qian, Hongbing Gu, Zixun Sun, Fei Mao, Yongmin Yan, Jingyan Chen, Zhaofeng Liang, Wenrong Xu

Pages: 1473-1481 Published online on: 18 July 2017
Open Access

LHX3 is an early stage and radiosensitivity prognostic biomarker in lung adenocarcinoma

Xin Lin, Yan Li, Jin Wang, Fei Han, Shuang Lu, Yu Wang, Wenjian Luo, Mingqian Zhang

Pages: 1482-1490 Published online on: 18 July 2017
Open Access

Cytotoxic and chemosensitization effects of Scutellarin from traditional Chinese herb Scutellaria altissima L. in human prostate cancer cells

Chen Gao, Yinglu Zhou, Zhongling Jiang, Yuan Zhao, Dongjun Zhang, Xia Cong, Rongfeng Cao, Huatao Li, Wenru Tian

Pages: 1491-1499 Published online on: 24 July 2017

Heat shock-induced HIKESHI protects cell viability via nuclear translocation of heat shock protein 70

Toru Yanoma, Kyoichi Ogata, Takehiko Yokobori, Munenori Ide, Erito Mochiki, Yoshitaka Toyomasu, Mitsuhiro Yanai, Norimichi Kogure, Akiharu Kimura, Masaki Suzuki, Nobuhiro Nakazawa, Tuya Bai, Tetsunari Oyama, Takayuki Asao, Ken Shirabe, Hiroyuki Kuwano

Pages: 1500-1506 Published online on: 21 July 2017

Immunocytochemical stem cell markers can predict clinical stage of breast cancer

Pedro J. Gutiérrez Diez, Yanrong Su, Jose Russo

Pages: 1507-1516 Published online on: 14 July 2017

Hsp90 inhibitor induces KG-1a cell differentiation and apoptosis via Akt/NF-κB signaling

Jin-Hong Qin, Kun Wang, Xin-Lu Fu, Peng-Jun Zhou, Zhong Liu, Dan-Dan Xu, Yi-Fei Wang, De-Po Yang, Qiu-Ling Xie, Qiu-Ying Liu

Pages: 1517-1524 Published online on: 07 July 2017

Long non-coding RNA LINK-A promotes glioma cell growth and invasion via lactate dehydrogenase A

Dejun Wu, Bing Zhao, Xiaoyu Cao, Jinghai Wan

Pages: 1525-1532 Published online on: 12 July 2017

SYPL1 overexpression predicts poor prognosis of hepatocellular carcinoma and associates with epithelial-mesenchymal transition

Dong-Han Chen, Qiu-Wan Wu, Xiu-Dong Li, Shuang-Jia Wang, Zhi-Ming Zhang

Pages: 1533-1542 Published online on: 21 July 2017

miR-142 inhibits the migration and invasion of glioma by targeting Rac1

Wenyi Qin, Xiaofeng Rong, Jiangchuan Dong, Chao Yu, Juan Yang

Pages: 1543-1550 Published online on: 13 July 2017

Kindlin‑2 promotes clear cell renal cell carcinoma progression through the Wnt signaling pathway

Muhan Li, Xuelian Pei, Guoliang Wang, Jun Zhan, Juan Du, Hao Jiang, Yan Tang, Hongquan Zhang, Huiying He

Pages: 1551-1560 Published online on: 04 July 2017

Lactobacilli inhibit cervical cancer cell migration in vitro and reduce tumor burden in vivo through upregulation of E-cadherin

Xiaoxi Li, Hong Wang, Xingxing Du, Wenna Yu, Jingwen Jiang, Yanhong Geng, Xiaobing Guo, Xiuhua Fan, Cuiqing Ma

Pages: 1561-1568 Published online on: 05 July 2017

MicroRNA-326 inhibits cell proliferation and invasion, activating apoptosis in hepatocellular carcinoma by directly targeting LIM and SH3 protein 1

Shiping Hu, Yun Ran, Wenlin Chen, Yuncheng Zhang, Yongjian Xu

Pages: 1569-1578 Published online on: 12 July 2017

Iodine-131 induces apoptosis in human cardiac muscle cells through the p53/Bax/caspase-3 and PIDD/caspase-2/ t‑BID/cytochrome c/caspase-3 signaling pathway

Yansheng Wang, Changqing Liu, Jianchun Wang, Yang Zhang, Linlin Chen

Pages: 1579-1586 Published online on: 13 July 2017

Trichostatin A induces bladder cancer cell death via intrinsic apoptosis at the early phase and Sp1‑survivin downregulation at the late phase of treatment

Shou-Chieh Wang, Shou-Tsung Wang, Hung-Te Liu, Xiang-Yu Wang, She-Ching Wu, Lei-Chin Chen, Yi-Wen Liu

Pages: 1587-1596 Published online on: 06 July 2017

Enhanced anticancer effects of a mixture of low-dose mushrooms and Panax ginseng root extracts in human colorectal cancer cells

Mi So Lee, Mi-Sook Kim, Jae Kuk Yoo, Ji Young Lee, Jae Eun Ju, Youn Kyoung Jeong

Pages: 1597-1604 Published online on: 07 July 2017

ANP32A modulates cell growth by regulating p38 and Akt activity in colorectal cancer

Wei Yan, Zhun Bai, Juan Wang, Xumei Li, Bixia Chi, Xu Chen

Pages: 1605-1612 Published online on: 21 July 2017

The differential regulation of microRNAs is associated with oral cancer

Shih-Chang Tsai, Sheng-Fong Huang, Jo-Hua Chiang, Yen-Fu Chen, Chia-Chang Huang, Ming-Hsui Tsai, Fuu-Jen Tsai, Ming-Ching Kao, Jai-Sing Yang

Pages: 1613-1620 Published online on: 12 July 2017

miR-361-5p modulates metabolism and autophagy via the Sp1-mediated regulation of PKM2 in prostate cancer

Zhixin Ling, Dachuang Liu, Guangyuan Zhang, Qing Liang, Ping Xiang, Yan Xu, Conghui Han, Tao Tao

Pages: 1621-1628 Published online on: 25 July 2017

Carboxy-terminus Hsc70 interacting protein exerts a tumor inhibition function in head and neck cancer

Meng Xiao, Ming Yan, Jianjun Zhang, Qin Xu, Wantao Chen

Pages: 1629-1636 Published online on: 17 July 2017

High expression of TRIM29 (ATDC) contributes to poor prognosis and tumor metastasis by inducing epithelial‑mesenchymal transition in osteosarcoma

Si-Xiang Zeng, Qing-Chun Cai, Chi-Hua Guo, Li-Qiang Zhi, Xing Dai, Dang-Feng Zhang, Wei Ma

Pages: 1645-1654 Published online on: 21 July 2017

Clinical significance of miR-138 in patients with malignant melanoma through targeting of PDK1 in the PI3K/AKT autophagy signaling pathway

Fanjun Meng, Yuxia Zhang, Xing Li, Juan Wang, Zhiyu Wang

Pages: 1655-1662 Published online on: 19 July 2017

In vivo and in vitro inhibition of human gastric cancer progress by upregulating Kank1 gene

Tao Chen, Kun Wang, Xianzhou Tong

Pages: 1663-1669 Published online on: 17 July 2017

MicroRNA-202 inhibits cell proliferation, migration and invasion of glioma by directly targeting metadherin

Jinsheng Yang, Bo Fan, Yachao Zhao, Junchao Fang

Pages: 1670-1678 Published online on: 13 July 2017

miR‑206 inhibits cancer initiating cells by targeting EHF in gastric cancer

Yan-Cui Gong, Guo-Liang Ren, Bo Liu, Feng Li, Hong-Peng Zhao, Jing-Bo Chen, Yu-Peng Li, Hai-Hua Yu

Pages: 1688-1694 Published online on: 06 July 2017

Expression of epithelial-mesenchymal transition and cancer stem cell markers in colorectal adenocarcinoma: Clinicopathological significance

Ji Eun Choi, Jun Sang Bae, Myoung Jae Kang, Myoung Ja Chung, Kyu Yun Jang, Ho Sung Park, Woo Sung Moon

Pages: 1695-1705 Published online on: 05 July 2017

Upregulation of Wnt signaling under hypoxia promotes lung cancer progression

Chun-Fu Hong, Wei-You Chen, Cheng-Wen Wu

Pages: 1706-1714 Published online on: 12 July 2017

miRNA-125b regulates apoptosis of human non-small cell lung cancer via the PI3K/Akt/GSK3β signaling pathway

Yingyi Wang, Ming Zhao, Jieying Liu, Zhao Sun, Jianjiao Ni, Hongsheng Liu

Pages: 1715-1723 Published online on: 12 July 2017

Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma

Guohui Qin, Jingyao Lian, Dongli Yue, Xinfeng Chen, Shufeng Nan, Yu Qi, Bing Li, Guanghui Cui, Xiangnan Li, Song Zhao, Yi Zhang

Pages: 1724-1732 Published online on: 12 July 2017

Overexpression of SET oncoprotein is associated with tumor progression and poor prognosis in human gastric cancer

Xiaoning Yuan, Te Zhang, Xin Zheng, Yunfei Zhang, Tingting Feng, Pengfei Liu, Zhiting Sun, Shanshan Qin, Xuewen Liu, Liang Zhang, Jie Song, Ying Liu

Pages: 1733-1741 Published online on: 04 July 2017

Phosphorylation of Bcl-2 plays an important role in glycochenodeoxycholate-induced survival and chemoresistance in HCC

Maojun Zhou, Qi Zhang, Jinfeng Zhao, Mingmei Liao, Sailan Wen, Manyi Yang

Pages: 1742-1750 Published online on: 18 July 2017

miR-216b inhibits glioma cell migration and invasion through suppression of FoxM1

Tingting Zhang, Guangtao Ma, Yan Zhang, Hongda Huo, Yuqian Zhao

Pages: 1751-1759 Published online on: 17 July 2017

Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells

Masahiro Shibata, Mitsuro Kanda, Haruyoshi Tanaka, Shinichi Umeda, Takashi Miwa, Dai Shimizu, Masamichi Hayashi, Takahiro Inaishi, Noriyuki Miyajima, Yayoi Adachi, Yuko Takano, Kenichi Nakanishi, Dai Takeuchi, Sumiyo Noda, Yasuhiro Kodera, Toyone Kikumori

Pages: 1760-1766 Published online on: 10 July 2017

Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stress

Renhua Xu, Zhenwei Yuan, Lijuan Yang, Lele Li, Dan Li, Changjun Lv

Pages: 1767-1773 Published online on: 06 July 2017

MicroRNA-106a promotes cell migration and invasion by targeting tissue inhibitor of matrix metalloproteinase 2 in cervical cancer

Xia Li, Qi Zhou, Ling Tao, Chunxia Yu

Pages: 1774-1782 Published online on: 18 July 2017

MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells

Na Lam Hwang, Yong Jung Kang, Bokyung Sung, Seong Yeon Hwang, Jung Yoon Jang, Hye Jin Oh, Yu Ra Ahn, Do Hyun Kim, Su Jeong Kim, Sultan Ullah, Mohammad Akbar Hossain, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim

Pages: 1783-1789 Published online on: 18 July 2017

miR-125a-5p upregulation suppresses the proliferation and induces the cell apoptosis of lung adenocarcinoma by targeting NEDD9

Hong Zheng, Jianbo Wu, Jiachen Shi, Chunya Lu, Yuanyuan Wang, Qianqian Sun, Guojun Zhang, Guoqiang Zhao

Pages: 1790-1796 Published online on: 13 July 2017

Truncated apolipoprotein C-I induces apoptosis in neuroblastoma by activating caspases in the extrinsic and intrinsic pathways

Fei Guo, Wei Zhao, Lin Yang, Yang Yang, Saiqi Wang, Yingjun Wang, Zhaoming Li, Jiaxiang Wang

Pages: 1797-1805 Published online on: 14 July 2017

SMURF1 promotes the proliferation, migration and invasion of gastric cancer cells

Youmao Tao, Caixia Sun, Tao Zhang, Yan Song

Pages: 1806-1814 Published online on: 17 July 2017

TAZ inhibition restores sensitivity of cisplatin via AKT/mTOR signaling in lung adenocarcinoma

Wei Xu, Yunyan Wei, Yue Li, Yuan Yin, Weiwei Yuan, Yan Yang, Weihong Zhao, Jianqing Wu

Pages: 1815-1821 Published online on: 24 July 2017

Role of triosephosphate isomerase and downstream functional genes on gastric cancer

Tingting Chen, Zhigang Huang, Yunxiao Tian, Haiwei Wang, Ping Ouyang, Haoqin Chen, Lili Wu, Bode Lin, Rongwei He

Pages: 1822-1832 Published online on: 24 July 2017

Royal jelly lipophilic fraction induces antiproliferative effects on SH-SY5Y human neuroblastoma cells

Angelo Gismondi, Eleonora Trionfera, Lorena Canuti, Gabriele Di Marco, Antonella Canini

Pages: 1833-1844 Published online on: 24 July 2017

Inhibitory effects of 1,25(OH)2D3 on the proliferation of hepatocellular carcinoma cells through the downregulation of HDAC2

Jian Huang, Guozhen Yang, Yunzhu Huang, Shu Zhang

Pages: 1845-1850 Published online on: 24 July 2017

Let-7c-5p inhibits cell proliferation and induces cell apoptosis by targeting ERCC6 in breast cancer

Xiaonan Fu, Xuan Mao, Yuxiang Wang, Xianfeng Ding, Yongfeng Li

Pages: 1851-1856 Published online on: 19 July 2017

MicroRNA-379 acts as a tumor suppressor in non-small cell lung cancer by targeting the IGF‑1R-mediated AKT and ERK pathways

Fangzheng Zhou, Long Nie, Dali Feng, Siyan Guo, Ren'na Luo

Pages: 1857-1866 Published online on: 18 July 2017

Snail maintains metastatic potential, cancer stem-like properties, and chemoresistance in mesenchymal mouse breast cancer TUBO‑P2J cells

Sun Young Ma, Jin-Hee Park, Hana Jung, Sung-Min Ha, Yeonye Kim, Dong Hyen Park, Deuk Hee Lee, Sooyong Lee, In-Ho Chu, So Young Jung, Il-Hwan Kim, Il-Whan Choi, Chang Soo Choi, Saegwang Park

Pages: 1867-1876 Published online on: 18 July 2017

Targeting VEGFR and FGFR in head and neck squamous cell carcinoma in vitro

Roman C. Brands, Luise M. Knierim, Francesco De Donno, Valentin Steinacker, Stefan Hartmann, Axel Seher, Alexander C. Kübler, Urs D.A. Müller-Richter

Pages: 1877-1885 Published online on: 10 July 2017

Circulating levels of angiogenesis-related growth factors in breast cancer: A study to profile proteins responsible for tubule formation

Gemma A. Barron, Marie Goua, Klaus W.J. Wahle, Giovanna Bermano

Pages: 1886-1894 Published online on: 11 July 2017

Spica Prunellae extract suppresses the growth of human colon carcinoma cells by targeting multiple oncogenes via activating miR-34a

Yi Fang, Ling Zhang, Jianyu Feng, Wei Lin, Qiaoyan Cai, Jun Peng

Pages: 1895-1901 Published online on: 06 July 2017

Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling

Shibo Wei, Qing Fan, Liang Yang, Xiaodong Zhang, Yingbo Ma, Zhihong Zong, Xiangdong Hua, Dongming Su, Hongzhi Sun, Hangyu Li, Zhen Liu

Pages: 1902-1908 Published online on: 20 July 2017
Journal Cover

September 2017
Volume 38 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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