Journal Articles

Open Access

A sketch of known and novel MYCN-associated miRNA networks in neuroblastoma

Francesca Megiorni, Moreno Colaiacovo, Samantha Cialfi, Heather P. McDowell, Alessandro Guffanti, Simona Camero, Armando Felsani, Paul D. Losty, Barry Pizer, Rajeev Shukla, Carlo Cappelli, Eva Ferrara, Antonio Pizzuti, Anna Moles, Carlo Dominici

Pages: 3-20 Published online on: 06 June 2017
Open Access

GROα overexpression drives cell migration and invasion in triple negative breast cancer cells

Kruttika Bhat, Marianna Sarkissyan, Yanyuan Wu, Jaydutt V. Vadgama

Pages: 21-30 Published online on: 24 May 2017
Open Access

Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines

Yoshinari Okada, Shunsuke Kato, Yasuhiro Sakamoto, Takayuki Oishi, Chikashi Ishioka

Pages: 31-42 Published online on: 30 May 2017
Open Access

TRIM59 facilitates the proliferation of colorectal cancer and promotes metastasis via the PI3K/AKT pathway

Ye Sun, Bing Ji, Yifei Feng, Yue Zhang, Dongjian Ji, Chunyan Zhu, Sen Wang, Chuan Zhang, Dongsheng Zhang, Yueming Sun

Pages: 43-52 Published online on: 22 May 2017
Open Access

Fisetin inhibits liver cancer growth in a mouse model: Relation to dopamine receptor

Xiang-Feng Liu, Hai-Jiao Long, Xiong-Ying Miao, Guo-Li Liu, Hong-Liang Yao

Pages: 53-62 Published online on: 30 May 2017
Open Access

Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK

Jie Shi, Bingyu Guo, Qiang Hui, Peng Chang, Kai Tao

Pages: 63-70 Published online on: 30 May 2017
Open Access

Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection

Elodie Melsens, Elly De Vlieghere, Benedicte Descamps, Christian Vanhove, Olivier De Wever, Wim Ceelen, Piet Pattyn

Pages: 71-81 Published online on: 15 May 2017
Open Access

MicroRNA-212 inhibits the metastasis of nasopharyngeal carcinoma by targeting SOX4

Chengyi Jiang, Hongtao Wang, Lei Zhou, Tao Jiang, Yajia Xu, Lin Xia

Pages: 82-88 Published online on: 15 May 2017
Open Access

Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice

Stefana Avram, Dorina‑Elena Coricovac, Ioana Zinuca Pavel, Iulia Pinzaru, Roxana Ghiulai, Flavia Baderca, Codruta Soica, Danina Muntean, Daciana E. Branisteanu, Demetrios A. Spandidos, Aristides M. Tsatsakis, Cristina Adriana Dehelean

Pages: 89-99 Published online on: 22 May 2017
Open Access

Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer

Yu-Zhen Feng, Qing-Yan Zhang, Mei-Ting Fu, Zhen-Fei Zhang, Min Wei, Jue-Yu Zhou, Rong Shi

Pages: 109-119 Published online on: 02 June 2017

Hypoxia-induced angiopoietin-like protein 4 as a clinical biomarker and treatment target for human prostate cancer

Shinro Hata, Takeo Nomura, Kazunori Iwasaki, Ryuta Sato, Mutsushi Yamasaki, Fuminori Sato, Hiromitsu Mimata

Pages: 120-128 Published online on: 24 May 2017

New bioactive peptide reduces the toxicity of chemotherapy drugs and increases drug sensitivity

Xian Li, Huijun Wu, Xiaohui Ouyang, Bo Zhang, Xiulan Su

Pages: 129-140 Published online on: 26 May 2017

Overexpression of microRNA-133b is associated with the increased survival of patients with hepatocellular carcinoma after curative hepatectomy: Involvement of the EGFR/PI3K/Akt/mTOR signaling pathway

Xuedong Wang, Jianping Zeng, Liang Wang, Xinjing Zhang, Zhiqian Liu, Hongyi Zhang, Jiahong Dong

Pages: 141-150 Published online on: 06 June 2017

MicroRNA-200c regulates cisplatin resistance by targeting ZEB2 in human gastric cancer cells

Tao Jiang, Pengfei Dong, Long Li, Xiao Ma, Pei Xu, He Zhu, Yanqiu Wang, Baotong Yang, Kuangge Liu, Jinwei Liu, Juan Xue, Runzhe Lv, Panke Su, Guoqiang Kong, Yongchao Chang, Chonggao Zhao, Lidong Wang

Pages: 151-158 Published online on: 22 May 2017

miR-130b regulates the proliferation, invasion and apoptosis of glioma cells via targeting of CYLD

Zhi-Qiang Xiao, Teng-Kun Yin, Ya-Xing Li, Jian-He Zhang, Jian-Jun Gu

Pages: 167-174 Published online on: 19 May 2017

miR-455 inhibits cell proliferation and migration via negative regulation of EGFR in human gastric cancer

Tao Ning, Zhijuan Peng, Shuang Li, Yanjun Qu, Haiyang Zhang, Jingjing Duan, Xinyi Wang, Haiou Yang, Rui Liu, Ting Deng, Ming Bai, Yi Wang, Yiran Si, Le Zhang, Xia Wang, Shaohua Ge, Likun Zhou, Guoguang Ying, Yi Ba

Pages: 175-182 Published online on: 22 May 2017

High expression of PIWIL2 promotes tumor cell proliferation, migration and predicts a poor prognosis in glioma

Jinquan Li, Li Xu, Zhen Bao, Peng Xu, Hao Chang, Jingjing Wu, Yuanqi Bei, Liuwan Xia, Peizhang Wu, Gang Cui

Pages: 183-192 Published online on: 17 May 2017

p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2

Liang-Hui Li, Guo-Yang Wu, Yi-Zhuo Lu, Xue-Hua Chen, Bing‑Ya Liu, Min-Hua Zheng, Jian-Chun Cai

Pages: 193-200 Published online on: 16 May 2017

Expression of the EP300, TP53 and BAX genes in colorectal cancer: Correlations with clinicopathological parameters and survival

Anna E. Kowalczyk, Bartlomiej E. Krazinski, Janusz Godlewski, Jolanta Kiewisz, Przemyslaw Kwiatkowski, Agnieszka Sliwinska-Jewsiewicka, Jacek Kiezun, Marian Sulik, Zbigniew Kmiec

Pages: 201-210 Published online on: 01 June 2017

Functional significance of the long non-coding RNA RP11-169D4.1 as a metastasis suppressor in laryngeal squamous cell carcinoma by regulating CDH1

Jing Zhao, Kexing Lv, Zeng-Hong Li, Jianhui Wu, Wei Gao, Thian-Sze Wong, Jie Luo, Hao Qin, Bin Wang, Qingling Fu, Wen-Bin Lei

Pages: 211-220 Published online on: 16 May 2017

NHERF1 inhibits proliferation of triple-negative breast cancer cells by suppressing GPER signaling

Yan Wang, Zhiqiang Peng, Ran Meng, Tao Tao, Qiqi Wang, Chunjuan Zhao, Hua Liu, Ran Song, Junfang Zheng, Qiong Qin, Junqi He

Pages: 221-228 Published online on: 18 May 2017

HDAC6 inhibition suppresses chondrosarcoma by restoring the expression of primary cilia

Wei Xiang, Fengjing Guo, Weiting Cheng, Jiaming Zhang, Junming Huang, Rui Wang, Zhongxi Ma, Kai Xu

Pages: 229-236 Published online on: 02 June 2017

MARK2 inhibits the growth of HeLa cells through AMPK and reverses epithelial-mesenchymal transition

Ge Xu, Yinggang Ge, Xiaohong Tao, Qing Gao, Xiaoyan Liang

Pages: 237-244 Published online on: 30 May 2017

Synergistic role of Cul1 and c-Myc: Prognostic and predictive biomarkers in colorectal cancer

Weimin Wang, Jianliang Deng, Qianqian Wang, Qiang Yao, Wenjiao Chen, Yongfei Tan, Zhijun Ge, Jianwei Zhou, Yan Zhou

Pages: 245-252 Published online on: 25 May 2017

Silencing of type Iγ phosphatidylinositol phosphate kinase suppresses ovarian cancer cell proliferation, migration and invasion

Siyu Cao, Chunhua Chen, Junli Xue, Yan Huang, Xiaofeng Yang, Kun Ling

Pages: 253-262 Published online on: 25 May 2017

EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells

Elisabet Cuyàs, Bernardo Queralt, Begoña Martin-Castillo, Joaquim Bosch-Barrera, Javier A. Menendez

Pages: 263-270 Published online on: 30 May 2017

Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells

Xuewen Liu, Chao Duan, Juanli Ji, Te Zhang, Xiaoning Yuan, Yunfei Zhang, Wenjing Ma, Jingyuan Yang, Linsen Yang, Zhiguo Jiang, Huiliang Yu, Ying Liu

Pages: 271-278 Published online on: 18 May 2017

Genetic testing and counseling of a recipient after bone marrow transplant from a sibling harboring a germline BRCA1 pathogenic mutation

Petra Škerl, Mateja Krajc, Ana Blatnik, Srdjan Novaković

Pages: 279-282 Published online on: 06 June 2017

Loss of CSMD1 expression disrupts mammary duct formation while enhancing proliferation, migration and invasion

Mohamed Kamal, Deborah L. Holliday, Ewan E. Morrison, Valerie Speirs, Carmel Toomes, Sandra M. Bell

Pages: 283-292 Published online on: 22 May 2017

Microarray expression profile of long non-coding RNAs in paclitaxel-resistant human lung adenocarcinoma cells

Xin Tian, Hongyan Zhang, Bijun Zhang, Jianzhu Zhao, Tingting Li, Yanyan Zhao

Pages: 293-300 Published online on: 01 June 2017

MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/β-catenin signaling pathway

Long Peng, Zhanying Liu, Jian Xiao, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao

Pages: 301-308 Published online on: 06 June 2017

Silencing of BAG3 promotes the sensitivity of ovarian cancer cells to cisplatin via inhibition of autophagy

Shuang Qiu, Liang Sun, Ye Jin, Qi An, Changjiang Weng, Jianhua Zheng

Pages: 309-316 Published online on: 06 June 2017

Silencing of ATM expression by siRNA technique contributes to glioma stem cell radiosensitivity in vitro and in vivo

Yan Li, Luchun Li, Zhijuan Wu, Lulu Wang, Yongzhong Wu, Dairong Li, Uiwen Ma, Jianghe Shao, Huiqing Yu, Donglin Wang

Pages: 325-335 Published online on: 24 May 2017

HIF-1α inhibits IDH-1 expression in osteosarcoma

Deng-Cheng Liu, Xun Zheng, Yong Zho, Wan-Rong Yi, Zong-Huan Li, Xiang Hu, Ai-Xi Yu

Pages: 336-342 Published online on: 22 May 2017

miR-1247-5p functions as a tumor suppressor in human hepatocellular carcinoma by targeting Wnt3

Yuankui Chu, Weining Fan, Wenwei Guo, Yixin Zhang, Lixin Wang, Le Guo, Xiangguo Duan, Jun Wei, Guangxian Xu

Pages: 343-351 Published online on: 06 June 2017

Overexpression of miR-15b-5p promotes gastric cancer metastasis by regulating PAQR3

Chengcheng Zhao, Yan Li, Gang Chen, Fen Wang, Zhili Shen, Rongping Zhou

Pages: 352-358 Published online on: 26 May 2017

Ginsenoside Rd regulates the Akt/mTOR/p70S6K signaling cascade and suppresses angiogenesis and breast tumor growth

Eryun Zhang, Hailian Shi, Li Yang, Xiaojun Wu, Zhengtao Wang

Pages: 359-367 Published online on: 19 May 2017

miR-204 regulates the biological behavior of breast cancer MCF-7 cells by directly targeting FOXA1

Si-Qiao Shen, Lan-Shan Huang, Xiao-Ling Xiao, Xiao-Fei Zhu, Dan-Dan Xiong, Xue-Mei Cao, Kang-Lai Wei, Gang Chen, Zhen-Bo Feng

Pages: 368-376 Published online on: 16 May 2017

DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression

Hongling Zhang, Xuhong Chen, Dongming Li, Lulu Cui, Xin Li, Xiufeng Ye, Xiaochun Wan

Pages: 377-383 Published online on: 30 May 2017

miR-370 regulates cell proliferation and migration by targeting EGFR in gastric cancer

Tao Ning, Haiyang Zhang, Xinyi Wang, Shuang Li, Le Zhang, Ting Deng, Likun Zhou, Rui Liu, Xia Wang, Ming Bai, Shaohua Ge, Hongli Li, Dingzhi Huang, Guoguang Ying, Yi Ba

Pages: 384-392 Published online on: 23 May 2017

miR-30e acts as a tumor suppressor in hepatocellular carcinoma partly via JAK1/STAT3 pathway

Junjie Mao, Xiaojun Hu, Pengfei Pang, Bin Zhou, Dan Li, Hong Shan

Pages: 393-401 Published online on: 30 May 2017

XAF1 expression levels in a non-small cell lung cancer cohort and its potential association with carcinogenesis

Luciene Schluckebier, Veronica Aran, Joyce De Moraes, Heitor Paiva, Cinthya Sternberg, Carlos Gil Ferreira

Pages: 402-410 Published online on: 30 May 2017

Construction of disease-specific transcriptional regulatory networks identifies co-activation of four gene in esophageal squamous cell carcinoma

Yu Zhao, Li Min, Changqin Xu, Linlin Shao, Shuilong Guo, Rui Cheng, Jie Xing, Shengtao Zhu, Shutian Zhang

Pages: 411-417 Published online on: 30 May 2017

Low HtrA1 expression in patients with long‑standing ulcerative colitis and colorectal cancer

Emma Altobelli, Giovanni Latella, Manrico Morroni, Caterina Licini, Giovanni Tossetta, Roberta Mazzucchelli, Valerio F. Profeta, Gino Coletti, Pietro Leocata, Mario Castellucci, Mario Guerrieri, Reimondo Petrocelli, Berardo De Berardis, Marina De Padova, Gabriella Di Leonardo, Antonella Paladini, Filippo Mignosi, Gina Quaglione, Roberto Fagnano, Daniela Marzioni

Pages: 418-426 Published online on: 06 June 2017

Overexpression of the YAP1 oncogene in clear cell renal cell carcinoma is associated with poor outcome

Agnieszka Rybarczyk, Jakub Klacz, Agata Wronska, Marcin Matuszewski, Zbigniew Kmiec, Piotr M. Wierzbicki

Pages: 427-439 Published online on: 15 May 2017

N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma

Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Yoko Sekiya, Yoriko Yamashita, Fumitaka Kikkawa

Pages: 440-448 Published online on: 23 May 2017

Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities

Junko Masuda, Eiji Takayama, Warren Strober, Ayano Satoh, Yuji Morimoto, Yasuko Honjo, Tatsuo Ichinohe, Shin-Ichi Tokuno, Toshiaki Ishizuka, Takahiro Nakata, Akifumi Mizutani, Naoki Umemura, Atsushi Kitani, Ivan J. Fuss, Tsukasa Shigehiro, Harumi Kawaki, Masako Mizuno-kamiya, Nobuo Kondoh, Masaharu Seno

Pages: 449-455 Published online on: 17 May 2017

Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells

Yu-Hua Zeng, Lin-Yun Zhou, Qian-Zhao Chen, Yang Li, Ying Shao, Wen-Yan Ren, Yun-Peng Liao, Han Wang, Jia-Hui Zhu, Ming Huang, Fang He, Jin Wang, Ke Wu, Bai-Cheng He

Pages: 456-464 Published online on: 23 May 2017

Amplification and the clinical significance of circulating cell-free DNA of PVT1 in breast cancer

Xujing Li, Weijuan Chen, Hui Wang, Qun Wei, Xiaodi Ding, Wentong Li

Pages: 465-471 Published online on: 18 May 2017

The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma

Xiaoli Su, Dan Chen, Kai Yang, Qin Zhao, Dan Zhao, Xiaoqiang Lv, Yiran Ao

Pages: 472-480 Published online on: 19 May 2017

KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells

Yang Liu, Dong-Yeop Shin, Somi Oh, Sujong Kim, Youngil Koh, Inho Kim

Pages: 481-487 Published online on: 01 June 2017

The blueberry component pterostilbene has potent anti-myeloma activity in bortezomib-resistant cells

Gege Chen, Zhijian Xu, Gaomei Chang, Jun Hou, Liangning Hu, Yiwen Zhang, Dandan Yu, Bo Li, Shuaikang Chang, Yongsheng Xie, Yong Zhang, Rong Wei, Huiqun Wu, Wenqin Xiao, Xi Sun, Yi Tao, Lu Gao, Bojie Dai, Jumei Shi, Weiliang Zhu

Pages: 488-496 Published online on: 30 May 2017

MicroRNA-497 acts as a tumor suppressor in gastric cancer and is downregulated by DNA methylation

Jichao Liu, Yongshuang Li, Ying Zou, Jiakui Zhang, Jiaxiang An, Jiao Guo, Minghui Ma, Dongqiu Dai

Pages: 497-505 Published online on: 06 June 2017

Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells

Emiko Akashi, Shintaro Fujihara, Asahiro Morishita, Tomoko Tadokoro, Taiga Chiyo, Keiko Fujikawa, Hideki Kobara, Hirohito Mori, Hisakazu Iwama, Keiichi Okano, Yasuyuki Suzuki, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 506-514 Published online on: 01 June 2017

Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening

Shuliang Zhou, Youde Xiao, Yafei Zhuang, Yinyin Liu, Hong Zhao, Hui Yang, Conghua Xie, Fuxiang Zhou, Yunfeng Zhou

Pages: 515-521 Published online on: 06 June 2017

Exosomes derived from hypoxic epithelial ovarian cancer deliver microRNA-940 to induce macrophage M2 polarization

Xin Chen, Xiang Ying, Xinjing Wang, Xiaoli Wu, Qinyi Zhu, Xipeng Wang

Pages: 522-528 Published online on: 06 June 2017

Methylated +322-327 CpG site decreases hOGG1 mRNA expression in non-small cell lung cancer

Yuanyuan Zeng, Jianjie Zhu, Hualong Qin, Dan Shen, Zhe Lei, Wei Li, Zongli Ding, Jian-An Huang, Zeyi Liu

Pages: 529-537 Published online on: 01 June 2017

Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma

Xiaoou Xu, Satoru Yokoyama, Yoshihiro Hayakawa, Ikuo Saiki

Pages: 538-544 Published online on: 26 May 2017

Reciprocal antagonistic regulation of N-myc mRNA by miR‑17 and the neuronal-specific RNA-binding protein HuD

Leleesha Samaraweera, Barbara A. Spengler, Robert A. Ross

Pages: 545-550 Published online on: 24 May 2017

Therapy-relevant aberrant expression of MRP3 and BCRP mRNA in TCC-/SCC-bladder cancer tissue of untreated patients

Mona Rady, Marwa Mostageer, Jan Rohde, Ashraf Zaghloul, Ruth Knüchel-Clarke, Shady Saad, Deena Attia, Laila Mahran, Hilde Spahn-Langguth

Pages: 551-560 Published online on: 02 June 2017

Treatment of colon cancer cells with 5-fluorouracil can improve the effectiveness of RNA-transfected antitumor dendritic cell vaccine

Carolina V. De Almeida, Jofer A. Zamame, Graziela G. Romagnoli, Cecilia P. Rodrigues, Marianna B. Magalhães, Amedeo Amedei, Ramon Kaneno

Pages: 561-568 Published online on: 01 June 2017

3,3'-diindolylmethane downregulates cyclin D1 through triggering endoplasmic reticulum stress in colorectal cancer cells

Xiaobo Zhang, Pakin Sukamporn, Shiqiang Zhang, Kyung-Won Min, Seung Joon Baek

Pages: 569-574 Published online on: 01 June 2017

Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway

Do-Hee Kim, Ji Eun Park, In Gyeong Chae, Geumi Park, Sooyeun Lee, Kyung-Soo Chun

Pages: 575-583 Published online on: 30 May 2017

KLF2 inhibits cell growth via regulating HIF-1α/Notch-1 signal pathway in human colorectal cancer HCT116 cells

Hai-Gang Wang, Bin Cao, Li-Xian Zhang, Nan Song, Hui Li, Wen-Zeng Zhao, Yan-Shu Li, Shun-Mao Ma, Dong-Jian Yin

Pages: 584-590 Published online on: 06 June 2017

Arctigenin inhibits triple-negative breast cancers by targeting CIP2A to reactivate protein phosphatase 2A

Qiuyue Huang, Shanshan Qin, Xiaoning Yuan, Liang Zhang, Juanli Ji, Xuewen Liu, Wenjing Ma, Yunfei Zhang, Pengfei Liu, Zhiting Sun, Jingxuan Zhang, Ying Liu

Pages: 598-606 Published online on: 24 May 2017
Journal Cover

July 2017
Volume 38 Issue 1

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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