Journal Articles

Open Access

Concurrence of chromosome 3 and 4 aberrations in human uveal melanoma

Eva Sipos, Kata Hegyi, Andrea Treszl, Zita Steiber, Gabor Mehes, Nikoletta Dobos, Klara Fodor, Gabor Olah, Lorant Szekvolgyi, Andrew V. Schally, Gabor Halmos

Pages: 1927-1934 Published online on: 08 March 2017
Open Access

FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide

Jian Ma, Jianlei Li, Xiaoling Yao, Shuangjun Lin, Ye Gu, Jianfang Xu, Zixin Deng, Wei Ma, Haiping Zhang

Pages: 1935-1942 Published online on: 01 March 2017
Open Access

Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma

Masafumi Chiba, Hiroo Imazu, Masayuki Kato, Keiichi Ikeda, Hiroshi Arakawa, Tomohiro Kato, Kazuki Sumiyama, Sadamu Homma

Pages: 1943-1952 Published online on: 21 February 2017
Open Access

EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer

Ding-Ping Sun, Chia-Lang Fang, Han-Kun Chen, Kuo-Shan Wen, You-Cheng Hseu, Shih-Ting Hung, Yih-Huei Uen, Kai-Yuan Lin

Pages: 1953-1960 Published online on: 14 February 2017
Open Access

Pleomorphic adenoma gene like-2 induces epithelial-mesenchymal transition via Wnt/β-catenin signaling pathway in human colorectal adenocarcinoma

Yong-Peng Wang, Peng-Tao Guo, Zhi Zhu, Hao Zhang, Yan Xu, Yu-Ze Chen, Fang Liu, Si-Ping Ma

Pages: 1961-1970 Published online on: 02 March 2017
Open Access

Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Xijuan Cui, Hong Ji, Yiming Li, Ya'an Kang

Pages: 1971-1979 Published online on: 28 February 2017
Open Access

miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM

Yuyan Guo, Wenze Sun, Tuotuo Gong, Yanlan Chai, Juan Wang, Beina Hui, Yi Li, Liping Song, Ying Gao

Pages: 1980-1988 Published online on: 14 February 2017
Open Access

Chemosensitizing effect of shRNA-mediated ERCC1 silencing on a Xuanwei lung adenocarcinoma cell line and its clinical significance

Weiwei Wang, Lijun Zhang, Liang Liu, Yongfa Zheng, Yong Zhang, Siyuan Yang, Rongliang Shi, Shaojia Wang

Pages: 1989-1997 Published online on: 14 February 2017
Open Access

G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways

Yizhuo Wang, Huijie Xiao, Haitao Wu, Cheng Yao, Hua He, Chang Wang, Wei Li

Pages: 1998-2006 Published online on: 13 March 2017
Open Access

Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells

Padmamalini Thulasiraman, Galen Garriga, Veena Danthuluri, Daniel J. McAndrews, Imran Q. Mohiuddin

Pages: 2007-2015 Published online on: 08 March 2017

Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro

Zhang-Feng Zhong, Wen Tan, Ke Tian, Hua Yu, Wen-An Qiang, Yi-Tao Wang

Pages: 2016-2024 Published online on: 10 February 2017

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity

Masashi Shiiba, Hitomi Yamagami, Ayumi Yamamoto, Yasuyuki Minakawa, Atsushi Okamoto, Atsushi Kasamatsu, Yosuke Sakamoto, Katsuhiro Uzawa, Yuichi Takiguchi, Hideki Tanzawa

Pages: 2025-2032 Published online on: 01 March 2017

ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126

Junqing Wang, Yunyun Zhou, Xiaochun Fei, Xuehua Chen, Jiqi Yan, Bingya Liu, Zhenggang Zhu

Pages: 2033-2040 Published online on: 16 February 2017

Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300

Liping Wang, Xin Huang, Yurong Chai, Liyang Zou, Matthew Chedrawe, Yi Ding

Pages: 2041-2048 Published online on: 14 February 2017

Atorvastatin prolongs the lifespan of radiation‑induced reactive oxygen species in PC-3 prostate cancer cells to enhance the cell killing effect

Hao Yu, Shao-Qian Sun, Xiao-Bin Gu, Wen Wang, Xian-Shu Gao

Pages: 2049-2056 Published online on: 14 February 2017

Dysregulation of TMPRSS3 and TNFRSF11B correlates with tumorigenesis and poor prognosis in patients with breast cancer

Ping Luo, Gaixia Lu, Lin‑Lin Fan, Xiaoming Zhong, Huiqiong Yang, Ruting Xie, Zhongwei Lv, Qian‑Zhou Lv, Da Fu, Li‑Xin Yang, Yushui Ma

Pages: 2057-2062 Published online on: 14 February 2017

Tumor-penetrating peptide fused to a pro-apoptotic peptide facilitates effective gastric cancer therapy

Ying Huang, Xihan Li, Huizi Sha, Lianru Zhang, Xinyu Bian, Xiao Han, Baorui Liu

Pages: 2063-2070 Published online on: 10 February 2017

Upregulation of miR-137 reverses sorafenib resistance and cancer-initiating cell phenotypes by degrading ANT2 in hepatocellular carcinoma

Ai-Qing Lu, Bin Lv, Fei Qiu, Xiao-Yun Wang, Xiao-Hua Cao

Pages: 2071-2078 Published online on: 10 March 2017

A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells

Xiaoli Dai, Jing Liu, Yin Nian, Ming-Hua Qiu, Ying Luo, Jihong Zhang

Pages: 2079-2086 Published online on: 14 February 2017

Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1

Tong-Han Zhang, Li-Zhong Liang, Xiao-Ling Liu, Ji-Nan Wu, Kui Su, Jue-Yao Chen, Qiao-Yi Zheng, Hong-Zhang Huang, Gui-Qing Liao

Pages: 2087-2094 Published online on: 14 February 2017

CXCL8 induces epithelial-mesenchymal transition in colon cancer cells via the PI3K/Akt/NF-κB signaling pathway

Tao Shen, Zhibin Yang, Xianshuo Cheng, Youchuan Xiao, Kun Yu, Xinyi Cai, Cuifeng Xia, Yunfeng Li

Pages: 2095-2100 Published online on: 14 February 2017

Identification of novel cancer fusion genes using chromosome breakpoint screening

Kate Hua, Chin-Hui Lin, Ya-Lun Chen, Chi-Hung Lin, Yueh‑Hsin Ping, Yuh-Shan Jou, Chian-Feng Chen

Pages: 2101-2108 Published online on: 06 March 2017

Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism

Chao Wang, Huan Wang, Yaqian Zhang, Wei Guo, Cong Long, Jingchao Wang, Limei Liu, Xiaoping Sun

Pages: 2109-2120 Published online on: 02 March 2017

Cx32 reverses epithelial-mesenchymal transition in doxorubicin-resistant hepatocellular carcinoma

Meiling Yu, Guangshu Han, Benquan Qi, Xiaoxiang Wu

Pages: 2121-2128 Published online on: 17 February 2017

Overexpression of miR-203 increases the sensitivity of NSCLC A549/H460 cell lines to cisplatin by targeting Dickkopf-1

Ruirui Cheng, Chunya Lu, Guojun Zhang, Guowei Zhang, Guoqiang Zhao

Pages: 2129-2136 Published online on: 13 March 2017

High expression of PINK1 promotes proliferation and chemoresistance of NSCLC

Rui Zhang, Jun Gu, Jie Chen, Jun Ni, Jieru Hung, Zhiwen Wang, Xiaochen Zhang, Jian Feng, Lili Ji

Pages: 2137-2146 Published online on: 02 March 2017

Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer in vitro

Zongping Wang, Jie Kang, Xianzhao Deng, Bomin Guo, Bo Wu, Youben Fan

Pages: 2147-2152 Published online on: 10 February 2017

Absence of Malat1 does not prevent DEN-induced hepatocarcinoma in mice

Stéphanie Miard, Marie-Josée Girard, Philippe Joubert, Sophie Carter, Amy Gonzales, Huiping Guo, Benjamin Morpurgo, Louise Boivin, Andrei Golovko, Frédéric Picard

Pages: 2153-2160 Published online on: 20 February 2017

Enhanced expression of PKM2 associates with the biological properties of cancer stem cells from A549 human lung cancer cells

Chang-Ying Guo, Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Jian-Jun Xu, Xiao-Ming Wen, Yu-Kang Kuang, Fang-Fang Tou, Tao-Sheng Li

Pages: 2161-2166 Published online on: 10 February 2017

High expression of RBM8A predicts poor patient prognosis and promotes tumor progression in hepatocellular carcinoma

Rong Liang, Yan Lin, Jia-Zhou Ye, Xue-Xin Yan, Zhi-Hui Liu, Yong-Qiang Li, Xiao-Ling Luo, Hai-Hong Ye

Pages: 2167-2176 Published online on: 15 February 2017

Combined treatment with vitamin C and methotrexate inhibits triple-negative breast cancer cell growth by increasing H2O2 accumulation and activating caspase-3 and p38 pathways

Ching-Wen Wu, Hsiao-Chun Liu, Yung-Luen Yu, Yu-Ting Hung, Chyou-Wei Wei, Giou-Teng Yiang

Pages: 2177-2184 Published online on: 10 February 2017

MicroRNA-365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu

Pages: 2185-2192 Published online on: 16 February 2017

miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1

Yan Li, Lifen Zhao, Nana Li, Yuan Miao, Huimin Zhou, Li Jia

Pages: 2193-2200 Published online on: 17 February 2017

AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis

Yun Jung Choi, Ji Hye Kim, Jin Kyung Rho, Joong Sun Kim, Chang-Min Choi, Woo Sung Kim, Jaekyoung Son, Jae Cheol Lee

Pages: 2201-2208 Published online on: 01 March 2017

Runx2 downregulation, migration and proliferation inhibition in melanoma cells treated with BEL β-trefoil

Massimiliano Perduca, Luca Dalle Carbonare, Michele Bovi, Giulio Innamorati, Samuele Cheri, Chiara Cavallini, Maria Teresa Scupoli, Antonio Mori, Maria Teresa Valenti

Pages: 2209-2214 Published online on: 06 March 2017
Open Access

TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma

Song Ye, Xin-Yi Zhao, Xiao-Ge Hu, Tang Li, Qiu-Ran Xu, Huan-Ming Yang, Dong-Sheng Huang, Liu Yang

Pages: 2215-2226 Published online on: 08 March 2017

Anti-hepatoma activities of ethyl acetate extract from Ampelopsis sinica root

Jia-Zhi Wang, Bi-Sheng Huang, Yan Cao, Ke-Li Chen, Juan Li

Pages: 2227-2236 Published online on: 13 March 2017

Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727

Xiaolong Zhang, Xiaoyi Wu, Fangling Zhang, Shouyong Mo, Yuanyuan Lu, Wei Wei, Xiaoling Chen, Linhua Lan, Bin Lu, Yongzhang Liu

Pages: 2237-2244 Published online on: 13 March 2017

Knockdown of PARP6 or survivin promotes cell apoptosis and inhibits cell invasion of colorectal adenocarcinoma cells

Haipeng Wang, Shengguo Li, Xishun Luo, Zhike Song, Xiangkai Long, Xijia Zhu

Pages: 2245-2251 Published online on: 14 February 2017

GSH depletion and consequent AKT inhibition contribute to the Nrf2 knockdown-induced decrease in proliferation in glioblastoma U251 cells

Yue Jia, Han-Dong Wang, Qiang Wang, Hui Ding, He-Ming Wu, Hao Pan

Pages: 2252-2260 Published online on: 20 February 2017

FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression

Runze Shang, Meng Pu, Yu Li, Desheng Wang

Pages: 2261-2269 Published online on: 22 February 2017

Increased expression of HOXB9 in hepatocellular carcinoma predicts poor overall survival but a beneficial response to sorafenib

Naokazu Chiba, Yosuke Ozawa, Kosuke Hikita, Masaaki Okihara, Toru Sano, Koichi Tomita, Kiminori Takano, Shigeyuki Kawachi

Pages: 2270-2276 Published online on: 23 February 2017

Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells

Guangming Zhao, Xiaodong Han, Wei Cheng, Jing Ni, Yunfei Zhang, Jingrong Lin, Zhiqi Song

Pages: 2277-2285 Published online on: 14 February 2017

Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer

Zhuolian Yin, Yong Sun, Sufang Ge, Juxiang Sun

Pages: 2286-2294 Published online on: 17 February 2017

pSTAT5 and ERK exhibit different expression in myeloproliferative neoplasms

Ewa Wiśniewska-Chudy, Łukasz Szylberg, Grzegorz Dworacki, Ewa Mizera-Nyczak, Andrzej Marszałek

Pages: 2295-2307 Published online on: 24 February 2017

Roles of immune inhibitory molecule B7-H4 in cervical cancer

Sai Han, Yi Li, Jingjing Zhang, Lu Liu, Qian Chen, Qiuhong Qian, Shan Li, Youzhong Zhang

Pages: 2308-2316 Published online on: 01 March 2017

The anti-metastatic effect of baicalein on colorectal cancer

Yuxia Chai, Jizhong Xu, Baojun Yan

Pages: 2317-2323 Published online on: 10 February 2017

HPV16 oncogenes E6 or/and E7 may influence the methylation status of RASSFIA gene promoter region in cervical cancer cell line HT-3

Fufen Yin, Ning Wang, Shanshan Wang, Fengsheng Yu, Xin Sun, Xiao Yu, Bing Luo, Chengquan Zhao, Yankui Wang

Pages: 2324-2334 Published online on: 17 February 2017

Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes

Shu Chen, Simin Jiang, Fen Hu, Yongjian Xu, Tao Wang, Qi Mei

Pages: 2335-2347 Published online on: 16 February 2017

Osthole enhances TRAIL-mediated apoptosis through downregulation of c-FLIP expression in renal carcinoma Caki cells

Kyoung-Jin Min, Min Ae Han, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon

Pages: 2348-2354 Published online on: 06 March 2017

Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing

Qiaozhen Yang, Bin Guo, Hongying Sun, Jie Zhang, Shangfeng Liu, Saiyin Hexige, Xuedi Yu, Xiaxia Wang

Pages: 2355-2365 Published online on: 02 March 2017

Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line

Rie Tamaki, Aya Kanai-Mori, Yuta Morishige, Atsushi Koike, Kazuyoshi Yanagihara, Fumio Amano

Pages: 2366-2374 Published online on: 20 February 2017

CIRH1A augments the proliferation of RKO colorectal cancer cells

Feng Guo, Jian-Jun Chen, Wei-Jun Tang

Pages: 2375-2381 Published online on: 08 March 2017

Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy

James Griffith, Daniel Andrade, Meghna Mehta, William Berry, Doris M. Benbrook, Natarajan Aravindan, Terence S. Herman, Rajagopal Ramesh, Anupama Munshi

Pages: 2382-2390 Published online on: 28 February 2017

FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation

Ke Xu, Zhenhao Zhang, Hua Pei, Huamin Wang, Liang Li, Qianfeng Xia

Pages: 2391-2397 Published online on: 16 February 2017

USP39 promotes colorectal cancer growth and metastasis through the Wnt/β-catenin pathway

Xianwen Yuan, Xitai Sun, Xiaolei Shi, Hao Wang, Guoyi Wu, Chunping Jiang, Decai Yu, Weiwei Zhang, Bin Xue, Yitao Ding

Pages: 2398-2404 Published online on: 15 February 2017

Actin-like protein 6A is a novel prognostic indicator promoting invasion and metastasis in osteosarcoma

Wei Sun, Wanchun Wang, Jian Lei, Hui Li, Yi Wu

Pages: 2405-2417 Published online on: 23 February 2017

Co-treatment of breast cancer cells with pharmacologic doses of 2-deoxy-D-glucose and metformin: Starving tumors

Ulrike Wokoun, Martin Hellriegel, Günter Emons, Carsten Gründker

Pages: 2418-2424 Published online on: 06 March 2017

Berberine sensitizes nasopharyngeal carcinoma cells to radiation through inhibition of Sp1 and EMT

Jun Wang, Min Kang, Qin Wen, Yu-Tao Qin, Zhu-Xin Wei, Jing-Jian Xiao, Ren-Sheng Wang

Pages: 2425-2432 Published online on: 13 March 2017

Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF

Alicia González, Alicia González-González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos

Pages: 2433-2440 Published online on: 14 February 2017

MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3

Yanqi Liu, Yanhong Sun, Aizhen Zhao

Pages: 2441-2448 Published online on: 02 March 2017

MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer

Yongxiang Zhao, Mingyu Yan, Ye Yun, Jianguo Zhang, Ruimin Zhang, Yan Li, Xiangming Wu, Qiang Liu, Wei Miao, Haishan Jiang

Pages: 2449-2458 Published online on: 13 March 2017

Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells

Reina Hoshi, Yosuke Watanabe, Yoshiaki Ishizuka, Takayuki Hirano, Eri Nagasaki-Maeoka, Shinsuke Yoshizawa, Shota Uekusa, Hiroyuki Kawashima, Kensuke Ohashi, Kiminobu Sugito, Noboru Fukuda, Hiroki Nagase, Masayoshi Soma, Toshinori Ozaki, Tsugumichi Koshinaga, Kyoko Fujiwara

Pages: 2459-2464 Published online on: 24 February 2017

Stanniocalcin 1 promotes cell proliferation via cyclin E1/cyclin‑dependent kinase 2 in human prostate carcinoma

Yao Bai, Yichen Xiao, Yuanqing Dai, Xiong Chen, Dongjie Li, Xinji Tan, Xiaobo Zhang

Pages: 2465-2471 Published online on: 13 March 2017

Tumor-associated macrophages favor C26 murine colon carcinoma cell proliferation in an oxidative stress-dependent manner

Lavinia Luput, Emilia Licarete, Alina Sesarman, Laura Patras, Marius Costel Alupei, Manuela Banciu

Pages: 2472-2480 Published online on: 17 February 2017

Vinblastine differs from Taxol as it inhibits the malignant phenotypes of NSCLC cells by increasing the phosphorylation of Op18/stathmin

Fang Shen, Dan Long, Ting Yu, Xian Chen, Ying Liao, Yi Wu, Xuechi Lin

Pages: 2481-2489 Published online on: 20 February 2017

Upregulation of microRNA-125b-5p is involved in the pathogenesis of osteoarthritis by downregulating SYVN1

Feng‑Xiao Ge, Haitao Li, Xin Yin

Pages: 2490-2496 Published online on: 24 February 2017

Upregulation of p38 pathway accelerates proliferation and migration of MDA-MB-231 breast cancer cells

Hugo W. Huth, Daniel M. Santos, Humberto D. Gravina, Jarbas M. Resende, Alfredo M. Goes, Maria Elena de Lima, Catherine Ropert

Pages: 2497-2505 Published online on: 14 February 2017

Clinical and molecular assessment of regorafenib monotherapy

Nao Kakizawa, Koichi Suzuki, Taro Fukui, Yuji Takayama, Kosuke Ichida, Yuta Muto, Fumi Hasegawa, Fumiaki Watanabe, Rina Kikugawa, Shingo Tsujinaka, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Toshiki Rikiyama

Pages: 2506-2512 Published online on: 15 February 2017

miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway

Jie Xiao, Weifeng Yu, Kongzu Hu, Maoqiang Li, Jianwei Chen, Zhanchun Li

Pages: 2513-2521 Published online on: 02 March 2017
Open Access

[Corrigendum] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang

Pages: 2522-2522 Published online on: 15 February 2017
Journal Cover

April 2017
Volume 37 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2015 Impact Factor: 2.486
Ranked #31/211 Oncology
(total number of cites)

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