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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2008 Volume 20 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Oncoprotein Bcl-2 and microsatellite instability are associated with disease-free survival and treatment response in colorectal cancer

Riyad Bendardaf, Hanan Lamlum, Raija Ristamäki, Kari Syrjänen, Seppo Pyrhönen
Pages: 999-1004
Published online on: 01 November 2008

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Article

Expression of orotate phosphoribosyltransferase in colorectal carcinoma: An immunohistochemical analysis in several components of neoplastic lesions

Yuichi Sanada, Kazuhiro Yoshida, Jun Hihara, Morihito Okada
Pages: 1005-1011
Published online on: 01 November 2008

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Article

Positive KL-6 mucin expression combined with decreased membranous β-catenin expression indicates worse prognosis in colorectal carcinoma

Wei Zhang, Wei Tang, Yoshinori Inagaki, Ming Qiu, Huan-Li Xu, Xun Li, Yasuhiko Sugawara, Hirokazu Nagawa, Munehiro Nakata, Norihiro Kokudo
Pages: 1013-1019
Published online on: 01 November 2008

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Article

Expression of cytokeratin 7 predicts survival in stage I/IIA/IIB squamous cell carcinoma of the esophagus

Atsushi Yamada, Hiroki Sasaki, Kazuhiko Aoyagi, Masayuki Sano, Satoshi Fujii, Hiroyuki Daiko, Mitsuyo Nishimura, Teruhiko Yoshida, Tsutomu Chiba, Atsushi Ochiai
Pages: 1021-1027
Published online on: 01 November 2008

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Article

The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1

Ioannis Panagopoulos, Emely Möller, Anna Collin, Fredrik Mertens
Pages: 1029-1033
Published online on: 01 November 2008

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Article

Potent anti-hepatoma efficacy of HCCS1 via dual tumor-targeting gene-virotherapy strategy

Jian Zhang, Yu Gan, Jinfa Gu, Jingying Hu, Xinyuan Liu, Xintai Zhao
Pages: 1035-1040
Published online on: 01 November 2008

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Article

Overexpression of SENP5 in oral squamous cell carcinoma and its association with differentiation

Xiaojun Ding, Jian Sun, Lizhen Wang, Guolin Li, Yi Shen, Xiaojian Zhou, Wantao Chen
Pages: 1041-1045
Published online on: 01 November 2008

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Article

DNA damage sensor protein hRad9, a novel molecular target for lung cancer treatment

Takeshi Yuki, Yoshimasa Maniwa, Takefumi Doi, Kenji Okada, Wataru Nishio, Yoshitake Hayashi, Yutaka Okita
Pages: 1047-1052
Published online on: 01 November 2008

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Article

Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells

Shu Huang, Faming Zhang, Lin Miao, Huijie Zhang, Zhining Fan, Xuehao Wang, Guozhong Ji
Pages: 1053-1059
Published online on: 01 November 2008

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Article

CpG island methylation status in the EpCAM promoter region and gene expression

Guolong Yu, Xiangzhong Zhang, Huaqiao Wang, Derong Rui, Aihua Yin, Geng Qiu, Yunshao He
Pages: 1061-1067
Published online on: 01 November 2008

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Article

The expression and the functional roles of tissue factor and protease-activated receptor-2 on SW620 cells

Hong Zhou, Hongxin Hu, Wenxia Shi, Shucai Ling, Ting Wang, Haibo Wang
Pages: 1069-1076
Published online on: 01 November 2008

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Article

LAPTM4B overexpression is an independent prognostic marker in ovarian carcinoma

Yu Yang, Hua Yang, Michael A. McNutt, Fuxia Xiong, Xiu Nie, Li Li, Rouli Zhou
Pages: 1077-1083
Published online on: 01 November 2008

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Article

The phosphorylation of survivin Thr34 by p34cdc2 in carcinogenesis of oral submucous fibrosis

Shanghui Zhou, Lili Li, Xinchun Jian, Xinrong Ou, Haiying Jiang, Zhigang Yao, Chunjiao Xu, Jieying Peng
Pages: 1085-1091
Published online on: 01 November 2008

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Article

Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression

Bai-Li Chen, Jun Yu, Zhi-Rong Zeng, Wai-Kit Chu, Christine Y.P. Wong, Yuen-Yee Cheng, Joseph J.Y. Sung, Pin-Jin Hu, Wai K. Leung
Pages: 1093-1097
Published online on: 01 November 2008

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Article

Potential chemoprevention effect of dietary fucoxanthin on urinary bladder cancer EJ-1 cell line

Zhenya Zhang, Peijuan Zhang, Michito Hamada, Satoru Takahashi, Guoqing Xing, Jiqiang Liu, Norio Sugiura
Pages: 1099-1103
Published online on: 01 November 2008

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Article

Reconstruction of the proximal humerus after extensive extraarticular resection for osteosarcoma: A report of two cases with clavicula pro humero reconstruction

Yoshihiro Nishida, Satoshi Tsukushi, Yoshihisa Yamada, Yuzuru Kamei, Kazuhiro Toriyama, Naoki Ishiguro
Pages: 1105-1109
Published online on: 01 November 2008

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Article

Potential role of dendritic cell vaccination with MAGE peptides in gastrointestinal carcinomas

Fumiaki Tanaka, Naotsugu Haraguchi, Kenji Isikawa, Hiroshi Inoue, Masaki Mori
Pages: 1111-1116
Published online on: 01 November 2008

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Article

Expression of CXCL12 and CXCR4 in pT3-stage gastric cancer does not correlate with peritoneal metastasis

Kenji Tsuboi, Yasuhiro Kodera, Hayao Nakanishi, Seiji Ito, Yoshinari Mochizuki, Goro Nakayama, Masahiko Koike, Michitaka Fujiwara, Yoshitaka Yamamura, Akimasa Nakao
Pages: 1117-1123
Published online on: 01 November 2008

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Article

Fibroblast growth factor receptor 4 mutation and polymorphism in Japanese lung cancer

Hidefumi Sasaki, Katsuhiro Okuda, Osamu Kawano, Haruhiro Yukiue, Motoki Yano, Yoshitaka Fujii
Pages: 1125-1130
Published online on: 01 November 2008

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Article

Positive immunohistochemical staining of γH2AX is associated with tumor progression in gastric cancers from radiation-exposed patients

Kazuhiro Sentani, Naohide Oue, Naoya Sakamoto, Takashi Nishisaka, Toshiyuki Fukuhara, Hiroo Matsuura, Wataru Yasui
Pages: 1131-1136
Published online on: 01 November 2008

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Article

Quantitative p16 and ESR1 methylation in the peripheral blood of patients with non-small cell lung cancer

Yasuhiro Suga, Kuniharu Miyajima, Takefumi Oikawa, Junichi Maeda, Jitsuo Usuda, Naohiro Kajiwara, Tatsuo Ohira, Osamu Uchida, Masahiro Tsuboi, Takashi Hirano, Harubumi Kato, Norihiko Ikeda
Pages: 1137-1142
Published online on: 01 November 2008

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Article

Radiological imaging features of invasive micropapillary carcinoma of the breast and axillary lymph nodes

Kei Kubota, Yasuhiro Ogawa, Akihito Nishioka, Yoriko Murata, Satoshi Itoh, Norihiko Hamada, Kazuo Morio, Hironori Maeda, Yosuke Tanaka
Pages: 1143-1147
Published online on: 01 November 2008

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Article

Preclinical analysis of the antitumor efficacy of TS-1 using human uterine cervical cancer tumor xenografts

Nobutaka Nagai, Masaaki Komatsu, Mayu Yunokawa, Yuko Shiroyama, Eiji Hirata
Pages: 1149-1156
Published online on: 01 November 2008

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Article

Colorectal mesenchymal tumors - from smooth muscle tumors to stromal tumors

Wei-Chen Tai, Seng-Kee Chuah, Jui-Wei Lin, Hong-Hwa Chen, Hsuan-Ying Huang, Chung-Mou Kuo, Li-Na Yi, Chuan-Mo Lee, Chi-Sin Changchien, Tsung-Hui Hu
Pages: 1157-1164
Published online on: 01 November 2008

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Article

Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer

Masashi Tsuruta, Hideki Nishibori, Hirotoshi Hasegawa, Yoshiyuki Ishii, Takashi Endo, Tetsuro Kubota, Masaki Kitajima, Yuko Kitagawa
Pages: 1165-1172
Published online on: 01 November 2008

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Article

Maintenance immunotherapy in metastatic breast cancer

Francesco Recchia, Gigliola Sica, Giampiero Candeloro, Stefano Necozione, Roberta Bisegna, Massimo Bratta, Silvio Rea
Pages: 1173-1179
Published online on: 01 November 2008

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Article

The C1772T genetic polymorphism in human HIF-1α gene associates with expression of HIF-1α protein in breast cancer

Hye Ok Kim, Yong Hwa Jo, Juhie Lee, Sang Sook Lee, Kyung-Sik Yoon
Pages: 1181-1187
Published online on: 01 November 2008

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Article

Comparison between intravenous and oral postoperative adjuvant immunochemotherapy in patients with stage II colorectal cancer

Isao Ito, Masaya Mukai, Hiromi Ninomiya, Kyoko Kishima, Kazutoshi Tsuchiya, Takayuki Tajima, Yasuhisa Oida, Masato Nakamura, Hiroyasu Makuuchi
Pages: 1189-1194
Published online on: 01 November 2008

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Article

Microsatellite analysis of serum DNA in patients with oral squamous cell carcinoma

Yoshidou Kakimoto, Nobuharu Yamamoto, Takahiko Shibahara
Pages: 1195-1200
Published online on: 01 November 2008

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Article

Neurotrophins and their receptors in human lingual tonsil: an immunohistochemical analysis

Marco Artico, Elena Bronzetti, Laura M. Felici, Valentina Alicino, Brunella Ionta, Benedetto Bronzetti, Giuseppe Magliulo, Claudia Grande, Loris Zamai, Guido Pasquantonio, Marco De Vincentiis
Pages: 1201-1206
Published online on: 01 November 2008

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Article

Effects of combination treatment of bortezomib and dexamethasone in SCCHN cell lines depend on tumor cell specificity

Jens Wagenblast, Mehran Baghi, Christoph Arnoldner, Sotirios Bisdas, Wolfgang Gstöttner, Angelika May, Rainald Knecht, Markus Hambek
Pages: 1207-1211
Published online on: 01 November 2008

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Article

Interleukin 1β-511T gene (IL1β) polymorphism is correlated with gastric cancer in the Caucasian population: Results from a meta-analysis

Bruno Vincenzi, Giuseppe Patti, Sara Galluzzo, Francesco Pantano, Olga Venditti, Daniele Santini, Annamaria Ruzzo, Gaia Schiavon, Michele Caraglia, Monica Marra, Francesco Graziano, Giuseppe Tonini
Pages: 1213-1220
Published online on: 01 November 2008

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Article

Endometrial adenocarcinoma: An analysis of treatment and outcome

Louise M. Byrd, Richard Swindell, Daniel Webber-Rookes, R. Hannon, Robin D. Hunter, Jac Livsey, Susan E. Davidson
Pages: 1221-1228
Published online on: 01 November 2008

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Article

Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cells

Hui Sun, Bin Liu, Wei Wang, Guang-Shui Jiang, Wei Li, Ya-Pei Yang, Chun-Xiao Xu, Yun-Fei Yan, Xian-Xi Liu
Pages: 1229-1235
Published online on: 01 November 2008

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Article

Novel acyl sulfonamide LY573636-sodium: Effect on hematopoietic malignant cells

Talin Haritunians, Saskia Gueller, James O'Kelly, Robert Ilaria, H. Phillip Koeffler
Pages: 1237-1242
Published online on: 01 November 2008

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Article

Aberrant alternative splicing of human zinc finger gene ZNF268 in human hematological malignancy

Zhouzhou Zhao, Di Wang, Chengang Zhu, Huanjie Shao, Chong Sun, Hongling Qiu, Lu Xue, Junhua Xu, Mingxiong Guo, Wenxin Li
Pages: 1243-1248
Published online on: 01 November 2008

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Article

The histone-deacetylase inhibitor MS-275 and the CDK-inhibitor CYC-202 promote anti-tumor effects in hepatoma cell lines

Susanne Gahr, Gisela Peter, Thadäus Till Wissniowski, Eckhart G. Hahn, Christoph Herold, Matthias Ocker
Pages: 1249-1256
Published online on: 01 November 2008

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Article

Methylation-associated silencing of SFRP1 in renal cell carcinoma

Yasuo Awakura, Eijiro Nakamura, Noriyuki Ito, Toshiyuki Kamoto, Osamu Ogawa
Pages: 1257-1263
Published online on: 01 November 2008

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Article

The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas

Kentaro Kimura, Shinichi Toyooka, Kazunori Tsukuda, Hiromasa Yamamoto, Hiroshi Suehisa, Junichi Soh, Hiroki Otani, Takafumi Kubo, Keisuke Aoe, Nobukazu Fujimoto, Takumi Kishimoto, Yoshifumi Sano, Harvery I. Pass, Hiroshi Date
Pages: 1265-1268
Published online on: 01 November 2008

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Article

Impact of oxaliplatin and a novel DACH-platinum complex in the gene expression of HCT116 colon cancer cells

Siu-Kwong Pang, Chun-Wing Yu, Huaji Guan, Steve C.F. Au-Yeung, Yee-Ping Ho
Pages: 1269-1276
Published online on: 01 November 2008

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Article

In vitro photodynamic therapy in pediatric epithelial liver tumors promoted by hypericin

Guido Seitz, Renita Krause, Jörg Fuchs, Heike Heitmann, Sorin Armeanu, Peter Ruck, Steven W. Warmann
Pages: 1277-1282
Published online on: 01 November 2008

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Article

Proteasome inhibition by bortezomib does not translate into efficacy on two malignant glioma xenografts

Marianne Labussiere, Sophie Pinel, Suzanne Delfortrie, François Plenat, Pascal Chastagner
Pages: 1283-1287
Published online on: 01 November 2008

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Article

Inhibition of estrogen receptor positive and negative breast cancer cell lines with a growth hormone-releasing hormone antagonist

Stephan Seitz, Florian Hohla, Andrew V. Schally, Angelika Moder, Joerg B. Engel, Felicitas Horn, Josef Varga, Marta Zarandi, Olaf Ortmann, Frank Köster, Stefan Buchholz
Pages: 1289-1294
Published online on: 01 November 2008

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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