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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2009 Volume 22 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Limited role of surgery in the management of primary central nervous system lymphoma (Review)

Bo-Lin Liu, Jin-Xiang Cheng, Xiang Zhang, Wei Zhang, Hong Cheng
Pages: 439-449
Published online on: 01 September 2009

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Review

Peroxisome proliferator-activated receptor δ and gastric cancer (Review)

Chung W. Wu, Jun Yu, Joseph J.Y. Sung
Pages: 451-457
Published online on: 01 September 2009

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Article

Sporadic and radiation-associated papillary thyroid cancers can be distinguished using routine immunohistochemistry

Carsten Boltze, Armin Riecke, Christian G. Ruf, Matthias Port, Horst Nizze, Carola Kügler, Claudia Miethke, Nadine Wiest, Michael Abend
Pages: 459-467
Published online on: 01 September 2009

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Article

Upregulation of stem cell antigen-1 in the lung of neonatal mice exposed to environmental cigarette smoke

Alberto Izzotti, Francesco D'Agostini, Patrizia Larghero, Cristina Cartiglia, Giorgia Travaini, Roumen Balansky, Vernon E. Steele, Silvio De Flora
Pages: 469-474
Published online on: 01 September 2009

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Article

Down-regulation of transforming growth factor β receptor type III in hepatocellular carcinoma is not directly associated with genetic alterations or loss of heterozygosity

Hyun Jin Bae, Jung Woo Eun, Ji Heon Noh, Jeong Kyu Kim, Kwang Hwa Jung, Hong Jian Xie, Won Sang Park, Jung Young Lee, Suk Woo Nam
Pages: 475-480
Published online on: 01 September 2009

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Article Open Access

Association of cellular localization of glycogen synthase kinase 3β in the digestive tract with cancer development

Hiroshi Hirakawa, Toshiyuki Nakayama, Kenichiro Shibata, Ichiro Sekine
Pages: 481-485
Published online on: 01 September 2009

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Article

The association between genetic polymorphisms in CYP19 and breast cancer risk in Korean women

Ji Young Kim, Chang Suk Lee, Hye Ok Kim, Yong Hwa Jo, Juhie Lee, Min Hyung Jung, Hyung Hwan Baik, Wonchae Choe, Insug Kang, Kyung-Sik Yoon
Pages: 487-492
Published online on: 01 September 2009

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Article

Clinical significance of a single nucleotide polymorphism and allelic imbalance of matrix metalloproteinase-1 promoter region in prostate cancer

Norihiko Tsuchiya, Shintaro Narita, Teruaki Kumazawa, Takamitsu Inoue, Zhiyong Ma, Hiroshi Tsuruta, Mitsuru Saito, Yohei Horikawa, Takeshi Yuasa, Shigeru Satoh, Osamu Ogawa, Tomonori Habuchi
Pages: 493-499
Published online on: 01 September 2009

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Article

The effect of neoadjuvant therapy on the 5-fluorouracil metabolic and relative enzymes of oral squamous cell carcinoma

Tomomi Yamashita, Makoto Toida, Keizo Kato, Nguyen Khanh Long, Yasuo Miyazaki, Yuichiro Asaka, Daijiro Hatakeyama, Kazuhiro Yonemoto, Hiroki Makita, Yukihiro Kato, Toshiyuki Shibata
Pages: 501-507
Published online on: 01 September 2009

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Article

Selective lymphadenectomy of para-aortic lymph nodes for advanced gastric cancer

Takashi Fujimura, Keishi Nakamura, Katsunobu Oyama, Hiroshi Funaki, Hideto Fujita, Shinichi Kinami, Itasu Ninomiya, Sachio Fushida, Genichi Nishimura, Masato Kayahara, Tetsuo Ohta
Pages: 509-514
Published online on: 01 September 2009

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Article

Mutation detection of KRAS by high-resolution melting analysis in Chinese with gastric cancer

Zhi-Min Liu, Li-Na Liu, Mei Li, Qiu-Ping Zhang, Shi-Hua Cheng, Shen Lu
Pages: 515-520
Published online on: 01 September 2009

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Article

The expression of the o-linked n-acetylglucosamine containing epitope H in the gemistocytic, pilocytic and subependymal giant cell astrocytomas

Leonidas D. Arvanitis, George K. Koukoulis, Panagiotis Kanavaros
Pages: 521-524
Published online on: 01 September 2009

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Article

Inhibition of PI3 kinase/Akt pathway is required for BMP2-induced EMT and invasion

Myoung Hee Kang, Han Na Kang, Jung Lim Kim, Jun Suk Kim, Sang Cheul Oh, Young A. Yoo
Pages: 525-534
Published online on: 01 September 2009

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Article

The expression of high-mobility group protein box 1 correlates with the progression of non-small cell lung cancer

Xiaokun Shen, Lingzhi Hong, Huiming Sun, Minke Shi, Yong Song
Pages: 535-539
Published online on: 01 September 2009

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Article

CLIC4 mediates TGF-β1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer

Qin Yao, Xun Qu, Qifeng Yang, Mingqian Wei, Beihua Kong
Pages: 541-548
Published online on: 01 September 2009

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Article

Up-regulation of hTERT expression by low-dose cisplatin contributes to chemotherapy resistance in human hepatocellular cancer cells

Xian-Ling Guo, Nan-Nan Ma, Fei-Guo Zhou, Li Zhang, Xin-Xin Bu, Kai Sun, Jian-Rui Song, Rong Li, Bai-He Zhang, Meng-Chao Wu, Li-Xin Wei
Pages: 549-556
Published online on: 01 September 2009

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Article

Intracellular localization of survivin determines biological behavior in colorectal cancer

Guangying Qi, Handan Tuncel, Eriko Aoki, Shinji Tanaka, Sirou Oka, Iwao Kaneko, Mayumi Okamoto, Maasaki Tatsuka, Shiro Nakai, Fumio Shimamoto
Pages: 557-562
Published online on: 01 September 2009

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Article

Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression

Qingmin Sun, Rihong Cong, Hongli Yan, Haijuan Gu, Ying Zeng, Nannan Liu, Jie Chen, Bin Wang
Pages: 563-567
Published online on: 01 September 2009

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Article

Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein

Juan Sebastian Yakisich, Ingrid Ohlsson Lindblom, Åke Siden, Mabel H. Cruz
Pages: 569-574
Published online on: 01 September 2009

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Article

The significance of MDM2 SNP309 and p53 Arg72Pro in young women with breast cancer

Anna Lång, Pia Palmebäck Wegman, Sten Wingren
Pages: 575-579
Published online on: 01 September 2009

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Article

Activation of Vα24NKT cells in malignant pleural effusion in patients with lung cancer

Tetsuo Shimizu, Noriaki Takahashi, Masahiro Terakado, Ichiro Tsujino, Shu Hashimoto
Pages: 581-586
Published online on: 01 September 2009

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Article

Diagnostic relevance of overexpressed Nanog gene in early lung cancers

Shinya Nirasawa, Daisuke Kobayashi, Naoki Tsuji, Kageaki Kuribayashi, Naoki Watanabe
Pages: 587-591
Published online on: 01 September 2009

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Article

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: A case-control study in the Portuguese population

Susana N. Silva, Ana Paula Azevedo, Valdemar Teixeira, Julieta Esperança Pina, José Rueff, Jorge Francisco Gaspar
Pages: 593-598
Published online on: 01 September 2009

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Article

Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue

Yasushi Ide, Hao Zhang, Hiroshi Hamajima, Yasunori Kawaguchi, Yuichiro Eguchi, Toshihiko Mizuta, Kyosuke Yamamoto, Kazuma Fujimoto, Iwata Ozaki
Pages: 599-604
Published online on: 01 September 2009

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Article

Neoadjuvant chemotherapy with carboplatin and docetaxel in advanced ovarian cancer - a prospective multicenter phase II trial (PRIMOVAR)

Martin Pölcher, Sven Mahner, Olaf Ortmann, Jörn Hilfrich, Klaus Diedrich, Georg-Peter Breitbach, Cornelia Höss, Claudia Leutner, Michael Braun, Volker Möbus, Ina Karbe, Patrick Stimmler, Christian Rudlowski, Jörg Schwarz, Walther Kuhn
Pages: 605-613
Published online on: 01 September 2009

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Article

Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines

Kohei Shomori, Mako Yamamoto, Ichiro Arifuku, Kazuki Teramachi, Hisao Ito
Pages: 615-620
Published online on: 01 September 2009

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Article

Efficacy of 5-FU/LV plus CPT-11 as first-line adjuvant chemotherapy for stage IIIa colorectal cancer

Masaya Mukai, Kazutake Okada, Hiroshi Fukumitsu, Naoki Yazawa, Tatsuhiko Hoshikawa, Takayuki Tajima, Hitoshi Hirakawa, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 621-629
Published online on: 01 September 2009

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Article

NF-κB activation induced by Notch ligand stimulation in acute myeloid leukemia cells

Mai Itoh, Lu Fu, Shuji Tohda
Pages: 631-634
Published online on: 01 September 2009

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Article

Expression of the tumor suppressor ARHI inhibits the growth of pancreatic cancer cells by inducing G1 cell cycle arrest

Xinqing Lu, Jiaming Qian, Yinhua Yu, Hong Yang, Jingnan Li
Pages: 635-640
Published online on: 01 September 2009

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Article

In vitro experimental study of the relationship between the apparent diffusion coefficient and changes in cellularity and cell morphology

Yoshitsugu Matsumoto, Masahiro Kuroda, Ryohei Matsuya, Hirokazu Kato, Koichi Shibuya, Masataka Oita, Atsushi Kawabe, Hidenobu Matsuzaki, Junichi Asaumi, Jun Murakami, Kazunori Katashima, Masakazu Ashida, Takanori Sasaki, Tetsuro Sei, Susumu Kanazawa, Seiichi Mimura, Seiichiro Oono, Takuichi Kitayama, Seiji Tahara, Keiji Inamura
Pages: 641-648
Published online on: 01 September 2009

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Article

Expression of MUC1, MUC2, MUC5AC and MUC6 in cholangiocarcinoma: Prognostic impact

Sin Young Park, Sang Jae Roh, Yo Na Kim, Sung Zoo Kim, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Myoung Jae Kang, Dong Geun Lee, Woo Sung Moon
Pages: 649-657
Published online on: 01 September 2009

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Article

MAGE-D1 inhibits proliferation, migration and invasion of human breast cancer cells

Qiang Du, Yang Zhang, Xin-Xia Tian, Yan Li, Wei-Gang Fang
Pages: 659-665
Published online on: 01 September 2009

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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