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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2009 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular histology on the diagnostic cutting edge between malignant melanomas and cutaneous melanocytomas (Review)

Pascale Quatresooz, Claudine Pierard-Franchimont, Gerald E. Pierard
Pages: 1263-1267
Published online on: 01 December 2009

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Review

Medical management of brain metastases from lung cancer (Review)

Ryuya Yamanaka
Pages: 1269-1276
Published online on: 01 December 2009

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Review

Genetic and molecular alterations associated with oral squamous cell cancer (Review)

Mario Pérez-Sayáns, José M. Somoza-Martín, Francisco Barros-Angueira, María D. Reboiras-López, José M. Gándara Rey, Abel García-García
Pages: 1277-1282
Published online on: 01 December 2009

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Article Open Access

Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines

M. W. Roomi, Julio C. Monterrey, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1283-1291
Published online on: 01 December 2009

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Article

Increase in E-selectin expression in umbilical vein endothelial cells by anticancer drugs and inhibition by cimetidine

Jin Kawase, Soji Ozawa, Kenichi Kobayashi, Yoshihiro Imaeda, Shunji Umemoto, Sumio Matsumoto, Masakazu Ueda
Pages: 1293-1297
Published online on: 01 December 2009

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Article

Molecular and immunological aspects of p53 and p53-autoantibodies in head and neck squamous cell carcinoma

Christian Cordes, J. Von Lingen, T. Görögh, P. Ambrosch, S. Gottschlich, M. Hoffmann
Pages: 1299-1303
Published online on: 01 December 2009

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Article

Suppression of Akt1 expression by small interference RNA inhibits SGC7901 cell growth in vitro and in vivo

Xiao-Wei Cui, Feng-Juan Zhao, Jian Liu, Xiao-Mei Song, Peng Xu, Xuan Zhou, Jie Zhang, Tao Wang, Chun-Sheng Kang, Qing-Yu Zhang
Pages: 1305-1313
Published online on: 01 December 2009

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Article

Positive correlation between cyclooxygenase-2 and ABC-transporter expression in non-Hodgkin's lymphomas

Katarzyna Szczuraszek, Verena Materna, Agnieszka Halon, Grzegorz Mazur, Tomasz Wróbel, Kazimierz Kuliczkowski, Adam Maciejczyk, Maciej Zabel, Marcin Drag, Manfred Dietel, Hermann Lage, Pawel Surowiak
Pages: 1315-1323
Published online on: 01 December 2009

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Article

Substance P and NK-1R expression in oral precancerous epithelium

Miguel A. Gonzalez-Moles, S. Brener, I. Ruiz-Avila, J. A. Gil-Montoya, D. Tostes, M. Bravo, F. Esteban
Pages: 1325-1331
Published online on: 01 December 2009

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Article

CXCR4 nuclear localization follows binding of its ligand SDF-1 and occurs in metastatic but not primary renal cell carcinoma

Linhui Wang, Zhixiang Wang, Bo Yang, Qing Yang, Liang Wang, Yinghao Sun
Pages: 1333-1339
Published online on: 01 December 2009

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Article

Inhibition of prostate cancer by suicide gene targeting the FCY1 and HSV-TK genes

Qiao-Hong Yue, Xing-Bin Hu, Ying Yin, Ming-Quan Su, Xiao-Dong Cheng, Liu Yang, Tie-Cheng Zhou, Xiaoke Hao
Pages: 1341-1347
Published online on: 01 December 2009

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Article

Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model

Nicoletta Gagliano, Francesco Costa, Chiara Cossetti, Letizia Pettinari, Rosaria Bassi, Maurizio Chiriva-Internati, Everardo Cobos, Magda Gioia, Stefano Pluchino
Pages: 1349-1356
Published online on: 01 December 2009

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Article

Distinct effect of Chrysanthemum indicum Linné extracts on isoproterenol-induced growth of human hepatocellular carcinoma cells

Aihua Yuan, Zongfang Li, Xinqiu Li, Shanyong Yi, Shukui Wang, Kaiwang Shi, Jianmin Bian
Pages: 1357-1363
Published online on: 01 December 2009

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Article

Effect of 5-ALA-PDT on VEGF and PCNA expression in human NPC-bearing nude mice

Ying Xie, Zheng-Bo Wei, Zhe Zhang, Wensheng Wen, Guang-Wu Huang
Pages: 1365-1371
Published online on: 01 December 2009

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Article

Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma cells

Ji E. Park, Weon Y. Chang, Moonjae Cho
Pages: 1373-1379
Published online on: 01 December 2009

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Article

Interpretation of Pin-1 and VEGF-C expression in breast infiltrating duct carcinoma

Byung-Chul Kim, Song-Iy Han, Sung-Chul Lim
Pages: 1381-1390
Published online on: 01 December 2009

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Article

hSSTR2 expression and octreotide treatment reverses multidrug resistance of BxPC-3 human pancreatic cancer cells

Chenguang Sui, Qingyong Ma, Kejun Nan, Juxiang Xiao, Aili Suo, Huanchen Sha, Lei Zhao
Pages: 1391-1396
Published online on: 01 December 2009

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Article

Triptolide induces apoptosis in human anaplastic thyroid carcinoma cells by a p53-independent but NF-κB-related mechanism

Wenbo Zhu, Haiyan Hu, Pengxin Qiu, Guangmei Yan
Pages: 1397-1401
Published online on: 01 December 2009

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Article

Impaired immune function: An early marker for cancer cachexia

Joyce Faber, Arjan P. Vos, Diane Kegler, Josep Argilés, Alessandro Laviano, Johan Garssen, Ardy Van Helvoort
Pages: 1403-1406
Published online on: 01 December 2009

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Article

Alternative splicing variant of vascular endothelial growth factor-A is a critical prognostic factor in non-small cell lung cancer

Masahiro Matsuyama, Tsuyoshi Chijiwa, Yoshimasa Inoue, Yoshiyuki Abe, Masatake Nishi, Noriyuki Miyazaki, Daisuke Furukawa, Masaya Mukai, Hiroshi Suemizu, Yasutomo Sekido, Yoshito Ueyama, Masato Nakamura
Pages: 1407-1413
Published online on: 01 December 2009

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Article

The level of fasting serum insulin, but not adiponectin, is associated with the prognosis of early stage hepatocellular carcinoma

Satoshi Miuma, Tatsuki Ichikawa, Naota Taura, Hidetaka Shibata, Shigeyuki Takeshita, Motohisa Akiyama, Yasuhide Motoyoshi, Eisuke Ozawa, Masumi Fujimoto, Hiroshi Kawashimo, Hisamitsu Miyaaki, Katsumi Eguchi, Kazuhiko Nakao
Pages: 1415-1424
Published online on: 01 December 2009

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Article

Gene polymorphisms in TYMS, MTHFR, p53 and MDR1 as risk factors for breast cancer: A case-control study

L. A. Henríquez-Hernández, A. Murias-Rosales, A. Hernández González, A. Cabrera De León, B. N. Díaz-Chico, M. Mori De Santiago, L. Fernández Pérez
Pages: 1425-1433
Published online on: 01 December 2009

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Article

Depletion of PI3K p85α induces cell cycle arrest and apoptosis in colorectal cancer cells

Yan Sun, Shiyi Zhao, Hua Tian, Xiaoyun Xie, Faman Xiao, Kang Li, Yugang Song
Pages: 1435-1441
Published online on: 01 December 2009

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Article

High level MycN expression in non-MYCN amplified neuroblastoma is induced by the combination treatment nutlin-3 and doxorubicin and enhances chemosensitivity

Susan K. Peirce, Harry W. Findley
Pages: 1443-1449
Published online on: 01 December 2009

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Article

Comparison of protein expression in two prostate cancer cell-lines, LNCaP and DU145, after treatment with somatostatin

Zhaoxu Liu, Marcela Marquez, Sten Nilsson, Anders R. Holmberg
Pages: 1451-1458
Published online on: 01 December 2009

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Article

Characteristics of PBMC obtained from leukapheresis products and tumor biopsies of patients with non-small cell lung cancer

John R. Yannelli, Jo A. Tucker, Giovanna Hidalgo, Sara Perkins, Richard Kryscio, Edward A. Hirschowitz
Pages: 1459-1471
Published online on: 01 December 2009

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Article

Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors

Rachel Davis, Karan P. Singh, Razelle Kurzrock, Sharmila Shankar
Pages: 1473-1478
Published online on: 01 December 2009

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Article

Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells

Zhi Gao, Zhidong Xu, Ming-Szu Hung, Yu-Ching Lin, Tianyou Wang, Min Gong, Xiuyi Zhi, David M. Jablons, Liang You
Pages: 1479-1484
Published online on: 01 December 2009

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Article

Different expression patterns of organic anion transporting polypeptides in osteosarcomas, bone metastases and aneurysmal bone cysts

Richard Liedauer, Martin Svoboda, Katrin Wlcek, Ferdi Arrich, Walter Jäger, Cyril Toma, Theresia Thalhammer
Pages: 1485-1492
Published online on: 01 December 2009

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Article

Identification of mobile lipids in human cancer tissues by ex vivo diffusion edited HR-MAS MRS

Valeria Righi, Adele Mucci, Luisa Schenetti, Antonella Bacci, Raffaele Agati, Marco Leonardi, Riccardo Schiavina, Giuseppe Martorana, Giuseppina Liguori, Carlo Calabrese, Elisa Boschetti, Sergio Bonora, Vitaliano Tugnoli
Pages: 1493-1496
Published online on: 01 December 2009

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Article

Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production

Kun-Yong Kim, Ahmi Baek, Yun S. Park, Mi Y. Park, Jae H. Kim, Jong-Seok Lim, Myeong-Sok Lee, Suk R. Yoon, Hee G. Lee, Yoosik Yoon, Do-Young Yoon, Young Yang
Pages: 1497-1504
Published online on: 01 December 2009

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Article

Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo

Se-Jung Lee, Young-Hwa Cho, Heejong Kim, Keerang Park, Sung-Kyu Park, Sang-Do Ha, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1505-1512
Published online on: 01 December 2009

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Article

Down-regulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3

Eduardo Parpa, Arnaldo Ortega, Leonardo Saenz
Pages: 1513-1518
Published online on: 01 December 2009

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Article

Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma

Katrin Steinmann, Annett Sandner, Undraga Schagdarsurengin, Reinhard H. Dammann
Pages: 1519-1526
Published online on: 01 December 2009

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Article

Topoisomerase IIα expression in acute myeloid leukaemia cells that survive after exposure to daunorubicin or ara-C

Elisabet Tina, Malin Prenkert, Martin Höglund, Christer Paul, Ulf Tidefelt
Pages: 1527-1531
Published online on: 01 December 2009

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Article

5-Fluorouracil combined with apigenin enhances anticancer activity through induction of apoptosis in human breast cancer MDA-MB-453 cells

Eun J. Choi, Gun-Hee Kim
Pages: 1533-1537
Published online on: 01 December 2009

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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