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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2009 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular histology on the diagnostic cutting edge between malignant melanomas and cutaneous melanocytomas (Review)

Pascale Quatresooz, Claudine Pierard-Franchimont, Gerald E. Pierard
Pages: 1263-1267
Published online on: 01 December 2009

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Review

Medical management of brain metastases from lung cancer (Review)

Ryuya Yamanaka
Pages: 1269-1276
Published online on: 01 December 2009

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Review

Genetic and molecular alterations associated with oral squamous cell cancer (Review)

Mario Pérez-Sayáns, José M. Somoza-Martín, Francisco Barros-Angueira, María D. Reboiras-López, José M. Gándara Rey, Abel García-García
Pages: 1277-1282
Published online on: 01 December 2009

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Article Open Access

Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines

M. W. Roomi, Julio C. Monterrey, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1283-1291
Published online on: 01 December 2009

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Article

Increase in E-selectin expression in umbilical vein endothelial cells by anticancer drugs and inhibition by cimetidine

Jin Kawase, Soji Ozawa, Kenichi Kobayashi, Yoshihiro Imaeda, Shunji Umemoto, Sumio Matsumoto, Masakazu Ueda
Pages: 1293-1297
Published online on: 01 December 2009

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Article

Molecular and immunological aspects of p53 and p53-autoantibodies in head and neck squamous cell carcinoma

Christian Cordes, J. Von Lingen, T. Görögh, P. Ambrosch, S. Gottschlich, M. Hoffmann
Pages: 1299-1303
Published online on: 01 December 2009

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Article

Suppression of Akt1 expression by small interference RNA inhibits SGC7901 cell growth in vitro and in vivo

Xiao-Wei Cui, Feng-Juan Zhao, Jian Liu, Xiao-Mei Song, Peng Xu, Xuan Zhou, Jie Zhang, Tao Wang, Chun-Sheng Kang, Qing-Yu Zhang
Pages: 1305-1313
Published online on: 01 December 2009

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Article

Positive correlation between cyclooxygenase-2 and ABC-transporter expression in non-Hodgkin's lymphomas

Katarzyna Szczuraszek, Verena Materna, Agnieszka Halon, Grzegorz Mazur, Tomasz Wróbel, Kazimierz Kuliczkowski, Adam Maciejczyk, Maciej Zabel, Marcin Drag, Manfred Dietel, Hermann Lage, Pawel Surowiak
Pages: 1315-1323
Published online on: 01 December 2009

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Article

Substance P and NK-1R expression in oral precancerous epithelium

Miguel A. Gonzalez-Moles, S. Brener, I. Ruiz-Avila, J. A. Gil-Montoya, D. Tostes, M. Bravo, F. Esteban
Pages: 1325-1331
Published online on: 01 December 2009

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Article

CXCR4 nuclear localization follows binding of its ligand SDF-1 and occurs in metastatic but not primary renal cell carcinoma

Linhui Wang, Zhixiang Wang, Bo Yang, Qing Yang, Liang Wang, Yinghao Sun
Pages: 1333-1339
Published online on: 01 December 2009

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Article

Inhibition of prostate cancer by suicide gene targeting the FCY1 and HSV-TK genes

Qiao-Hong Yue, Xing-Bin Hu, Ying Yin, Ming-Quan Su, Xiao-Dong Cheng, Liu Yang, Tie-Cheng Zhou, Xiaoke Hao
Pages: 1341-1347
Published online on: 01 December 2009

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Article

Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model

Nicoletta Gagliano, Francesco Costa, Chiara Cossetti, Letizia Pettinari, Rosaria Bassi, Maurizio Chiriva-Internati, Everardo Cobos, Magda Gioia, Stefano Pluchino
Pages: 1349-1356
Published online on: 01 December 2009

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Article

Distinct effect of Chrysanthemum indicum Linné extracts on isoproterenol-induced growth of human hepatocellular carcinoma cells

Aihua Yuan, Zongfang Li, Xinqiu Li, Shanyong Yi, Shukui Wang, Kaiwang Shi, Jianmin Bian
Pages: 1357-1363
Published online on: 01 December 2009

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Article

Effect of 5-ALA-PDT on VEGF and PCNA expression in human NPC-bearing nude mice

Ying Xie, Zheng-Bo Wei, Zhe Zhang, Wensheng Wen, Guang-Wu Huang
Pages: 1365-1371
Published online on: 01 December 2009

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Article

Induction of matrix metalloproteinase-9 by galectin-7 through p38 MAPK signaling in HeLa human cervical epithelial adenocarcinoma cells

Ji E. Park, Weon Y. Chang, Moonjae Cho
Pages: 1373-1379
Published online on: 01 December 2009

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Article

Interpretation of Pin-1 and VEGF-C expression in breast infiltrating duct carcinoma

Byung-Chul Kim, Song-Iy Han, Sung-Chul Lim
Pages: 1381-1390
Published online on: 01 December 2009

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Article

hSSTR2 expression and octreotide treatment reverses multidrug resistance of BxPC-3 human pancreatic cancer cells

Chenguang Sui, Qingyong Ma, Kejun Nan, Juxiang Xiao, Aili Suo, Huanchen Sha, Lei Zhao
Pages: 1391-1396
Published online on: 01 December 2009

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Article

Triptolide induces apoptosis in human anaplastic thyroid carcinoma cells by a p53-independent but NF-κB-related mechanism

Wenbo Zhu, Haiyan Hu, Pengxin Qiu, Guangmei Yan
Pages: 1397-1401
Published online on: 01 December 2009

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Article

Impaired immune function: An early marker for cancer cachexia

Joyce Faber, Arjan P. Vos, Diane Kegler, Josep Argilés, Alessandro Laviano, Johan Garssen, Ardy Van Helvoort
Pages: 1403-1406
Published online on: 01 December 2009

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Article

Alternative splicing variant of vascular endothelial growth factor-A is a critical prognostic factor in non-small cell lung cancer

Masahiro Matsuyama, Tsuyoshi Chijiwa, Yoshimasa Inoue, Yoshiyuki Abe, Masatake Nishi, Noriyuki Miyazaki, Daisuke Furukawa, Masaya Mukai, Hiroshi Suemizu, Yasutomo Sekido, Yoshito Ueyama, Masato Nakamura
Pages: 1407-1413
Published online on: 01 December 2009

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Article

The level of fasting serum insulin, but not adiponectin, is associated with the prognosis of early stage hepatocellular carcinoma

Satoshi Miuma, Tatsuki Ichikawa, Naota Taura, Hidetaka Shibata, Shigeyuki Takeshita, Motohisa Akiyama, Yasuhide Motoyoshi, Eisuke Ozawa, Masumi Fujimoto, Hiroshi Kawashimo, Hisamitsu Miyaaki, Katsumi Eguchi, Kazuhiko Nakao
Pages: 1415-1424
Published online on: 01 December 2009

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Article

Gene polymorphisms in TYMS, MTHFR, p53 and MDR1 as risk factors for breast cancer: A case-control study

L. A. Henríquez-Hernández, A. Murias-Rosales, A. Hernández González, A. Cabrera De León, B. N. Díaz-Chico, M. Mori De Santiago, L. Fernández Pérez
Pages: 1425-1433
Published online on: 01 December 2009

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Article

Depletion of PI3K p85α induces cell cycle arrest and apoptosis in colorectal cancer cells

Yan Sun, Shiyi Zhao, Hua Tian, Xiaoyun Xie, Faman Xiao, Kang Li, Yugang Song
Pages: 1435-1441
Published online on: 01 December 2009

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Article

High level MycN expression in non-MYCN amplified neuroblastoma is induced by the combination treatment nutlin-3 and doxorubicin and enhances chemosensitivity

Susan K. Peirce, Harry W. Findley
Pages: 1443-1449
Published online on: 01 December 2009

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Article

Comparison of protein expression in two prostate cancer cell-lines, LNCaP and DU145, after treatment with somatostatin

Zhaoxu Liu, Marcela Marquez, Sten Nilsson, Anders R. Holmberg
Pages: 1451-1458
Published online on: 01 December 2009

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Article

Characteristics of PBMC obtained from leukapheresis products and tumor biopsies of patients with non-small cell lung cancer

John R. Yannelli, Jo A. Tucker, Giovanna Hidalgo, Sara Perkins, Richard Kryscio, Edward A. Hirschowitz
Pages: 1459-1471
Published online on: 01 December 2009

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Article

Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors

Rachel Davis, Karan P. Singh, Razelle Kurzrock, Sharmila Shankar
Pages: 1473-1478
Published online on: 01 December 2009

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Article

Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells

Zhi Gao, Zhidong Xu, Ming-Szu Hung, Yu-Ching Lin, Tianyou Wang, Min Gong, Xiuyi Zhi, David M. Jablons, Liang You
Pages: 1479-1484
Published online on: 01 December 2009

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Article

Different expression patterns of organic anion transporting polypeptides in osteosarcomas, bone metastases and aneurysmal bone cysts

Richard Liedauer, Martin Svoboda, Katrin Wlcek, Ferdi Arrich, Walter Jäger, Cyril Toma, Theresia Thalhammer
Pages: 1485-1492
Published online on: 01 December 2009

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Article

Identification of mobile lipids in human cancer tissues by ex vivo diffusion edited HR-MAS MRS

Valeria Righi, Adele Mucci, Luisa Schenetti, Antonella Bacci, Raffaele Agati, Marco Leonardi, Riccardo Schiavina, Giuseppe Martorana, Giuseppina Liguori, Carlo Calabrese, Elisa Boschetti, Sergio Bonora, Vitaliano Tugnoli
Pages: 1493-1496
Published online on: 01 December 2009

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Article

Adipocyte culture medium stimulates invasiveness of MDA-MB-231 cell via CCL20 production

Kun-Yong Kim, Ahmi Baek, Yun S. Park, Mi Y. Park, Jae H. Kim, Jong-Seok Lim, Myeong-Sok Lee, Suk R. Yoon, Hee G. Lee, Yoosik Yoon, Do-Young Yoon, Young Yang
Pages: 1497-1504
Published online on: 01 December 2009

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Article

Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo

Se-Jung Lee, Young-Hwa Cho, Heejong Kim, Keerang Park, Sung-Kyu Park, Sang-Do Ha, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1505-1512
Published online on: 01 December 2009

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Article

Down-regulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3

Eduardo Parpa, Arnaldo Ortega, Leonardo Saenz
Pages: 1513-1518
Published online on: 01 December 2009

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Article

Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma

Katrin Steinmann, Annett Sandner, Undraga Schagdarsurengin, Reinhard H. Dammann
Pages: 1519-1526
Published online on: 01 December 2009

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Article

Topoisomerase IIα expression in acute myeloid leukaemia cells that survive after exposure to daunorubicin or ara-C

Elisabet Tina, Malin Prenkert, Martin Höglund, Christer Paul, Ulf Tidefelt
Pages: 1527-1531
Published online on: 01 December 2009

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Article

5-Fluorouracil combined with apigenin enhances anticancer activity through induction of apoptosis in human breast cancer MDA-MB-453 cells

Eun J. Choi, Gun-Hee Kim
Pages: 1533-1537
Published online on: 01 December 2009

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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