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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2010 Volume 24 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Matrix metalloproteinase-2 and -9 in the urine of prostate cancer patients

Angelina Di Carlo, Angela Mariano, Daniela Terracciano, Matteo Ferro, Vittorino Montanaro, Mariano Marsicano, Giuseppe Di Lorenzo, Vincenzo Altieri, Vincenzo Macchia
Pages: 3-8
Published online on: 01 July 2010

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Article Open Access

Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas

Kouji Ohta, Ikuko Ogawa, Shigehiro Ono, Masaaki Taki, Kuniko Mizuta, Miwa Miyauchi, Masaaki Takechi, Hideo Shigeishi, Takashi Takata, Nobuyuki Kamata
Pages: 9-14
Published online on: 01 July 2010

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Article Open Access

Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells

Ramakumar Tummala, Paula Diegelman, Sonia M. Fiuza, Luis A.E. Batista de Carvalho, Maria Paula M. Marques, Debora L. Kramer, Kimberly Clark, Slavoljub Vujcic, Carl W. Porter, Lakshmi Pendyala
Pages: 15-24
Published online on: 01 July 2010

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Article

Two-stage treatment (Mukai's method) with hybrid 2-port HALS (Mukai's operation) for complete bowel obstruction by left colon cancer or rectal cancer

Masaya Mukai, Yasutomo Sekido, Tatsuhiko Hoshikawa, Naoki Yazawa, Hiroshi Fukumitsu, Kazutake Okada, Takayuki Tajima, Masato Nakamura, Kyouji Ogoshi
Pages: 25-30
Published online on: 01 July 2010

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Article

Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2

Nao Ohtsu, Kazuki Takaoka, Emi Segawa, Susumu Hashitani, Kazuma Noguchi, Hiromitsu Kishimoto, Masahiro Urade
Pages: 31-36
Published online on: 01 July 2010

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Article

Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line

H. K. Dibra, J. E. Brown, P. Hooley, I. D. Nicholl
Pages: 37-46
Published online on: 01 July 2010

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Article

Low SMC1A protein expression predicts poor survival in acute myeloid leukemia

Claudia Hömme, Utz Krug, Nicola Tidow, Bernd Schulte, Gabriele Kühler, Hubert Serve, Horst Bürger, Wolfgang E. Berdel, Martin Dugas, Achim Heinecke, Thomas Büchner, Steffen Koschmieder, Carsten Müller-Tidow
Pages: 47-56
Published online on: 01 July 2010

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Article

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry

Helgi H. Helgason, Judith Y.M. Engwegen, Marc Zapatka, Andrew Vincent, Annemieke Cats, Henk Boot, Jos H. Beijnen, Jan H.M. Schellens
Pages: 57-64
Published online on: 01 July 2010

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Article

AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion

Junxia Zhang, Lei Han, Anling Zhang, Yingyi Wang, Xiao Yue, Yongping You, Peiyu Pu, Chunsheng Kang
Pages: 65-72
Published online on: 01 July 2010

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Article

Implication of necrosis-linked p53 aggregation in acquired apoptotic resistance to 5-FU in MCF-7 multicellular tumour spheroids

Su Yeon Lee, Eui-Kyong Jeong, Hyun Min Jeon, Cho Hee Kim, Ho Sung Kang
Pages: 73-79
Published online on: 01 July 2010

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Article

Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-β in melanoma development and progression

Grazia Malaponte, Alessandra Zacchia, Ylenia Bevelacqua, Andrea Marconi, Rosario Perrotta, Maria Clorinda Mazzarino, Vera Cardile, Franca Stivala
Pages: 81-87
Published online on: 01 July 2010

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Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway

Yu-Gang Wen, Quan Wang, Chong-Zhi Zhou, Guo-Qiang Qiu, Zhi-Hai Peng, Hua-Mei Tang
Pages: 89-95
Published online on: 01 July 2010

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Article

Hypoxia-inducible factor-1α modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer

Jianbao Zheng, Xuejun Sun, Wei Wang, Shaoying Lu
Pages: 97-104
Published online on: 01 July 2010

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Article

Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells

Jian Pan, Hai Hu, Zhuan Zhou, Lichao Sun, Liang Peng, Long Yu, Lixin Sun, Jun Liu, Zhihua Yang, Yuliang Ran
Pages: 105-112
Published online on: 01 July 2010

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Akt associates with nuclear factor κB and plays an important role in chemoresistance of gastric cancer cells

Liang-Liang Yu, Ning Dai, Hong-Gang Yu, Lei-Min Sun, Jian-Min Si
Pages: 113-119
Published online on: 01 July 2010

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Article

Genomic change of chromosome 8 predicts the response to taxane-based neoadjuvant chemotherapy in node-positive breast cancer

Sehwan Han, Kyeongmee Park, Eunah Shin, Hyun-Jung Kim, Jung Yeon Kim, Ji Young Kim, Geumhee Gwak
Pages: 121-128
Published online on: 01 July 2010

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Immunohistochemial evaluation of sarcoglycans and integrins in gingival epithelium of multiple myeloma patients with bisphosphonate-induced osteonecrosis of the jaw

Enrico Nastro Siniscalchi, Giuseppina Cutroneo, Luciano Catalfamo, Giuseppe Santoro, Alessandro Allegra, Giacomo Oteri, Domenico Cicciù, Andrea Alonci, Giuseppa Penna, Caterina Musolino, Francesco Saverio De Ponte, Giuseppe Anastasi, Angelo Favaloro
Pages: 129-134
Published online on: 01 July 2010

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Article

Programmed cell death 4 protein in esophageal cancer

Matteo Fassan, Matteo Cagol, Gianmaria Pennelli, Christian Rizzetto, Luciano Giacomelli, Giorgio Battaglia, Giovanni Zaninotto, Ermanno Ancona, Alberto Ruol, Massimo Rugge
Pages: 135-139
Published online on: 01 July 2010

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Article

Aristolochic acid suppresses DNA repair and triggers oxidative DNA damage in human kidney proximal tubular cells

Ya-Yin Chen, Jing-Gung Chung, Hsiu-Ching Wu, Da-Tian Bau, Kuen-Yuh Wu, Shung-Te Kao, Chien-Yun Hsiang, Tin-Yun Ho, Su-Yin Chiang
Pages: 141-153
Published online on: 01 July 2010

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Article

FGF-2 is overexpressed in myoepithelial cells of carcinoma ex-pleomorphic adenoma in situ structures

Elizabeth F. Martinez, Ana P.D. Demasi, Lucyene Miguita, Albina Altemani, Ney S. Araújo, Vera C. Araújo
Pages: 155-160
Published online on: 01 July 2010

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Article

Validated analysis of HIF-1α expression in cancer cells using a controlled and comparative immunoassay

Maria Ioannou, Ilias Mylonis, Evangelos Kouvaras, Rodula Papamichali, Alexandros Daponte, Efrosyni Paraskeva, George Simos, George K. Koukoulis
Pages: 161-169
Published online on: 01 July 2010

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Article

A variant of estrogen receptor-α, ER-α36 is expressed in human gastric cancer and is highly correlated with lymph node metastasis

Hao Deng, Xuan Huang, Jun Fan, Liubai Wang, Qin Xia, Xiuping Yang, Zhaoyi Wang, Lijiang Liu
Pages: 171-176
Published online on: 01 July 2010

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Article

Photodynamic therapy with hexenyl ester of 5-aminolevulinic acid induces necrotic cell death in salivary gland adenocarcinoma cells

Jong-Hwan Park, Yeon-Hee Moon, Dong-Jae Kim, Soo-A Kim, Jee-Bum Lee, Sang-Gun Ahn, Jung-Hoon Yoon
Pages: 177-181
Published online on: 01 July 2010

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Article

HSG provides antitumor efficacy on hepatocellular carcinoma both in vitro and in vivo

Weilin Wang, Feng Zhu, Shuqian Wang, Jianfeng Wei, Changku Jia, Yuanbiao Zhang, Lin Zhou, Haiyang Xie, Shusen Zheng
Pages: 183-188
Published online on: 01 July 2010

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Article

c-Met antisense oligodeoxynucleotides increase sensitivity of human glioma cells to paclitaxel

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Hong Zhang, Jian-Hua Qiu, Zhi-An Zhu
Pages: 189-194
Published online on: 01 July 2010

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Article

Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3

Xuan Zhou, Junxia Zhang, Qiang Jia, Yu Ren, Yingyi Wang, Lei Shi, Ning Liu, Guangxiu Wang, Peiyu Pu, Yongping You, Chunsheng Kang
Pages: 195-201
Published online on: 01 July 2010

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Article

Human tissue-specific microenvironment: An essential requirement for mouse models of breast cancer

Tian-Song Xia, Jue Wang, Hong Yin, Qiang Ding, Yi-Fen Zhang, Hai-Wei Yang, Xiao-An Liu, Min Dong, Qing Du, Li-Jun Ling, Xiao-Ming Zha, Wei Fu, Shui Wang
Pages: 203-211
Published online on: 01 July 2010

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Article Open Access

Effects of the ErbB1/ErbB2 kinase inhibitor GW2974 on androgen-independent prostate cancer PC-3 cell line growth and NSE, chromogranin A and osteopontin content

Daniela Terracciano, Claudia Mazzarella, Angelina Di Carlo, Angela Mariano, Matteo Ferro, Giuseppe Di Lorenzo, Antonio Giordano, Vincenzo Altieri, Sabino De Placido, Vincenzo Macchia
Pages: 213-217
Published online on: 01 July 2010

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Article

Spindle cells from AIDS-associated Kaposi's sarcoma lesions express telomerase activity that is enhanced by Kaposi's sarcoma progression factors

Giovanni Barillari, Ornella Franzese, Alessandro Comandini, Enzo Bonmassar, Barbara Ensoli
Pages: 219-223
Published online on: 01 July 2010

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Article

Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway

Nozomi Nomi, Satoru Kodama, Masashi Suzuki
Pages: 225-231
Published online on: 01 July 2010

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Article

Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other anticancer agents

Kazutaka Koto, Hiroaki Murata, Shinya Kimura, Naoyuki Horie, Takaaki Matsui, Yasunori Nishigaki, Kazuteru Ryu, Tomoya Sakabe, Megumi Itoi, Eishi Ashihara, Taira Maekawa, Shinji Fushiki, Toshikazu Kubo
Pages: 233-239
Published online on: 01 July 2010

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Article

Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas

Masashi Shiiba, Hitomi Nomura, Keiji Shinozuka, Kengo Saito, Yukinao Kouzu, Atsushi Kasamatsu, Yosuke Sakamoto, Akiyuki Murano, Kanae Ono, Katsunori Ogawara, Katsuhiro Uzawa, Hideki Tanzawa
Pages: 241-249
Published online on: 01 July 2010

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Article

MEK1 and MEK2 isoforms regulate distinct functions in pancreatic cancer cells

Lei Zhou, Xiaodong Tan, Hidenobu Kamohara, Wei Wang, Baosheng Wang, Jingang Liu, Hiroshi Egami, Hideo Baba, Xianwei Dai
Pages: 251-255
Published online on: 01 July 2010

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Article

Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk

Weimin Gao, Marjorie Romkes, Shilong Zhong, Tomoko Nukui, Raj A. Persad, Patrick J.B. Smith, Robert Branch, Phouthone Keohavong
Pages: 257-262
Published online on: 01 July 2010

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Article

Identification of a 17-protein signature in the serum of lung cancer patients

Roman T. Sreseli, Harald Binder, Madeleine Kuhn, Werner Digel, Hendrik Veelken, Wulf Sienel, Bernward Passlick, Martin Schumacher, Uwe M. Martens, Stefan Zimmermann
Pages: 263-270
Published online on: 01 July 2010

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Article

Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C

Dong-Oh Moon, Mun-Ock Kim, Taek-Jeong Nam, Se-Kwon Kim, Yung Hyun Choi, Gi-Young Kim
Pages: 271-276
Published online on: 01 July 2010

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Article

Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by apigenin via the inhibition of p38 mitogen-activated protein kinase-dependent matrix metalloproteinase-9 expression

Hyo-Jeong Noh, Eon-Gi Sung, Joo-Young Kim, Tae-Jin Lee, In-Hwan Song
Pages: 277-283
Published online on: 01 July 2010

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Article

Role of CDK8 and β-catenin in colorectal adenocarcinoma

Jong-Og Seo, Song Iy Han, Sung-Chul Lim
Pages: 285-291
Published online on: 01 July 2010

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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