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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2010 Volume 24 Issue 1

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Matrix metalloproteinase-2 and -9 in the urine of prostate cancer patients

Angelina Di Carlo, Angela Mariano, Daniela Terracciano, Matteo Ferro, Vittorino Montanaro, Mariano Marsicano, Giuseppe Di Lorenzo, Vincenzo Altieri, Vincenzo Macchia
Pages: 3-8
Published online on: 01 July 2010

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Article Open Access

Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas

Kouji Ohta, Ikuko Ogawa, Shigehiro Ono, Masaaki Taki, Kuniko Mizuta, Miwa Miyauchi, Masaaki Takechi, Hideo Shigeishi, Takashi Takata, Nobuyuki Kamata
Pages: 9-14
Published online on: 01 July 2010

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Article Open Access

Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells

Ramakumar Tummala, Paula Diegelman, Sonia M. Fiuza, Luis A.E. Batista de Carvalho, Maria Paula M. Marques, Debora L. Kramer, Kimberly Clark, Slavoljub Vujcic, Carl W. Porter, Lakshmi Pendyala
Pages: 15-24
Published online on: 01 July 2010

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Article

Two-stage treatment (Mukai's method) with hybrid 2-port HALS (Mukai's operation) for complete bowel obstruction by left colon cancer or rectal cancer

Masaya Mukai, Yasutomo Sekido, Tatsuhiko Hoshikawa, Naoki Yazawa, Hiroshi Fukumitsu, Kazutake Okada, Takayuki Tajima, Masato Nakamura, Kyouji Ogoshi
Pages: 25-30
Published online on: 01 July 2010

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Article

Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2

Nao Ohtsu, Kazuki Takaoka, Emi Segawa, Susumu Hashitani, Kazuma Noguchi, Hiromitsu Kishimoto, Masahiro Urade
Pages: 31-36
Published online on: 01 July 2010

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Article

Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line

H. K. Dibra, J. E. Brown, P. Hooley, I. D. Nicholl
Pages: 37-46
Published online on: 01 July 2010

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Article

Low SMC1A protein expression predicts poor survival in acute myeloid leukemia

Claudia Hömme, Utz Krug, Nicola Tidow, Bernd Schulte, Gabriele Kühler, Hubert Serve, Horst Bürger, Wolfgang E. Berdel, Martin Dugas, Achim Heinecke, Thomas Büchner, Steffen Koschmieder, Carsten Müller-Tidow
Pages: 47-56
Published online on: 01 July 2010

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Article

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry

Helgi H. Helgason, Judith Y.M. Engwegen, Marc Zapatka, Andrew Vincent, Annemieke Cats, Henk Boot, Jos H. Beijnen, Jan H.M. Schellens
Pages: 57-64
Published online on: 01 July 2010

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Article

AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion

Junxia Zhang, Lei Han, Anling Zhang, Yingyi Wang, Xiao Yue, Yongping You, Peiyu Pu, Chunsheng Kang
Pages: 65-72
Published online on: 01 July 2010

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Article

Implication of necrosis-linked p53 aggregation in acquired apoptotic resistance to 5-FU in MCF-7 multicellular tumour spheroids

Su Yeon Lee, Eui-Kyong Jeong, Hyun Min Jeon, Cho Hee Kim, Ho Sung Kang
Pages: 73-79
Published online on: 01 July 2010

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Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-β in melanoma development and progression

Grazia Malaponte, Alessandra Zacchia, Ylenia Bevelacqua, Andrea Marconi, Rosario Perrotta, Maria Clorinda Mazzarino, Vera Cardile, Franca Stivala
Pages: 81-87
Published online on: 01 July 2010

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Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway

Yu-Gang Wen, Quan Wang, Chong-Zhi Zhou, Guo-Qiang Qiu, Zhi-Hai Peng, Hua-Mei Tang
Pages: 89-95
Published online on: 01 July 2010

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Article

Hypoxia-inducible factor-1α modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer

Jianbao Zheng, Xuejun Sun, Wei Wang, Shaoying Lu
Pages: 97-104
Published online on: 01 July 2010

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Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells

Jian Pan, Hai Hu, Zhuan Zhou, Lichao Sun, Liang Peng, Long Yu, Lixin Sun, Jun Liu, Zhihua Yang, Yuliang Ran
Pages: 105-112
Published online on: 01 July 2010

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Akt associates with nuclear factor κB and plays an important role in chemoresistance of gastric cancer cells

Liang-Liang Yu, Ning Dai, Hong-Gang Yu, Lei-Min Sun, Jian-Min Si
Pages: 113-119
Published online on: 01 July 2010

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Genomic change of chromosome 8 predicts the response to taxane-based neoadjuvant chemotherapy in node-positive breast cancer

Sehwan Han, Kyeongmee Park, Eunah Shin, Hyun-Jung Kim, Jung Yeon Kim, Ji Young Kim, Geumhee Gwak
Pages: 121-128
Published online on: 01 July 2010

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Immunohistochemial evaluation of sarcoglycans and integrins in gingival epithelium of multiple myeloma patients with bisphosphonate-induced osteonecrosis of the jaw

Enrico Nastro Siniscalchi, Giuseppina Cutroneo, Luciano Catalfamo, Giuseppe Santoro, Alessandro Allegra, Giacomo Oteri, Domenico Cicciù, Andrea Alonci, Giuseppa Penna, Caterina Musolino, Francesco Saverio De Ponte, Giuseppe Anastasi, Angelo Favaloro
Pages: 129-134
Published online on: 01 July 2010

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Programmed cell death 4 protein in esophageal cancer

Matteo Fassan, Matteo Cagol, Gianmaria Pennelli, Christian Rizzetto, Luciano Giacomelli, Giorgio Battaglia, Giovanni Zaninotto, Ermanno Ancona, Alberto Ruol, Massimo Rugge
Pages: 135-139
Published online on: 01 July 2010

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Aristolochic acid suppresses DNA repair and triggers oxidative DNA damage in human kidney proximal tubular cells

Ya-Yin Chen, Jing-Gung Chung, Hsiu-Ching Wu, Da-Tian Bau, Kuen-Yuh Wu, Shung-Te Kao, Chien-Yun Hsiang, Tin-Yun Ho, Su-Yin Chiang
Pages: 141-153
Published online on: 01 July 2010

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Article

FGF-2 is overexpressed in myoepithelial cells of carcinoma ex-pleomorphic adenoma in situ structures

Elizabeth F. Martinez, Ana P.D. Demasi, Lucyene Miguita, Albina Altemani, Ney S. Araújo, Vera C. Araújo
Pages: 155-160
Published online on: 01 July 2010

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Article

Validated analysis of HIF-1α expression in cancer cells using a controlled and comparative immunoassay

Maria Ioannou, Ilias Mylonis, Evangelos Kouvaras, Rodula Papamichali, Alexandros Daponte, Efrosyni Paraskeva, George Simos, George K. Koukoulis
Pages: 161-169
Published online on: 01 July 2010

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Article

A variant of estrogen receptor-α, ER-α36 is expressed in human gastric cancer and is highly correlated with lymph node metastasis

Hao Deng, Xuan Huang, Jun Fan, Liubai Wang, Qin Xia, Xiuping Yang, Zhaoyi Wang, Lijiang Liu
Pages: 171-176
Published online on: 01 July 2010

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Article

Photodynamic therapy with hexenyl ester of 5-aminolevulinic acid induces necrotic cell death in salivary gland adenocarcinoma cells

Jong-Hwan Park, Yeon-Hee Moon, Dong-Jae Kim, Soo-A Kim, Jee-Bum Lee, Sang-Gun Ahn, Jung-Hoon Yoon
Pages: 177-181
Published online on: 01 July 2010

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Article

HSG provides antitumor efficacy on hepatocellular carcinoma both in vitro and in vivo

Weilin Wang, Feng Zhu, Shuqian Wang, Jianfeng Wei, Changku Jia, Yuanbiao Zhang, Lin Zhou, Haiyang Xie, Shusen Zheng
Pages: 183-188
Published online on: 01 July 2010

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Article

c-Met antisense oligodeoxynucleotides increase sensitivity of human glioma cells to paclitaxel

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Hong Zhang, Jian-Hua Qiu, Zhi-An Zhu
Pages: 189-194
Published online on: 01 July 2010

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Article

Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3

Xuan Zhou, Junxia Zhang, Qiang Jia, Yu Ren, Yingyi Wang, Lei Shi, Ning Liu, Guangxiu Wang, Peiyu Pu, Yongping You, Chunsheng Kang
Pages: 195-201
Published online on: 01 July 2010

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Human tissue-specific microenvironment: An essential requirement for mouse models of breast cancer

Tian-Song Xia, Jue Wang, Hong Yin, Qiang Ding, Yi-Fen Zhang, Hai-Wei Yang, Xiao-An Liu, Min Dong, Qing Du, Li-Jun Ling, Xiao-Ming Zha, Wei Fu, Shui Wang
Pages: 203-211
Published online on: 01 July 2010

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Article Open Access

Effects of the ErbB1/ErbB2 kinase inhibitor GW2974 on androgen-independent prostate cancer PC-3 cell line growth and NSE, chromogranin A and osteopontin content

Daniela Terracciano, Claudia Mazzarella, Angelina Di Carlo, Angela Mariano, Matteo Ferro, Giuseppe Di Lorenzo, Antonio Giordano, Vincenzo Altieri, Sabino De Placido, Vincenzo Macchia
Pages: 213-217
Published online on: 01 July 2010

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Article

Spindle cells from AIDS-associated Kaposi's sarcoma lesions express telomerase activity that is enhanced by Kaposi's sarcoma progression factors

Giovanni Barillari, Ornella Franzese, Alessandro Comandini, Enzo Bonmassar, Barbara Ensoli
Pages: 219-223
Published online on: 01 July 2010

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Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway

Nozomi Nomi, Satoru Kodama, Masashi Suzuki
Pages: 225-231
Published online on: 01 July 2010

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Article

Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other anticancer agents

Kazutaka Koto, Hiroaki Murata, Shinya Kimura, Naoyuki Horie, Takaaki Matsui, Yasunori Nishigaki, Kazuteru Ryu, Tomoya Sakabe, Megumi Itoi, Eishi Ashihara, Taira Maekawa, Shinji Fushiki, Toshikazu Kubo
Pages: 233-239
Published online on: 01 July 2010

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Article

Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas

Masashi Shiiba, Hitomi Nomura, Keiji Shinozuka, Kengo Saito, Yukinao Kouzu, Atsushi Kasamatsu, Yosuke Sakamoto, Akiyuki Murano, Kanae Ono, Katsunori Ogawara, Katsuhiro Uzawa, Hideki Tanzawa
Pages: 241-249
Published online on: 01 July 2010

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Article

MEK1 and MEK2 isoforms regulate distinct functions in pancreatic cancer cells

Lei Zhou, Xiaodong Tan, Hidenobu Kamohara, Wei Wang, Baosheng Wang, Jingang Liu, Hiroshi Egami, Hideo Baba, Xianwei Dai
Pages: 251-255
Published online on: 01 July 2010

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Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk

Weimin Gao, Marjorie Romkes, Shilong Zhong, Tomoko Nukui, Raj A. Persad, Patrick J.B. Smith, Robert Branch, Phouthone Keohavong
Pages: 257-262
Published online on: 01 July 2010

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Article

Identification of a 17-protein signature in the serum of lung cancer patients

Roman T. Sreseli, Harald Binder, Madeleine Kuhn, Werner Digel, Hendrik Veelken, Wulf Sienel, Bernward Passlick, Martin Schumacher, Uwe M. Martens, Stefan Zimmermann
Pages: 263-270
Published online on: 01 July 2010

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Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C

Dong-Oh Moon, Mun-Ock Kim, Taek-Jeong Nam, Se-Kwon Kim, Yung Hyun Choi, Gi-Young Kim
Pages: 271-276
Published online on: 01 July 2010

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Article

Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by apigenin via the inhibition of p38 mitogen-activated protein kinase-dependent matrix metalloproteinase-9 expression

Hyo-Jeong Noh, Eon-Gi Sung, Joo-Young Kim, Tae-Jin Lee, In-Hwan Song
Pages: 277-283
Published online on: 01 July 2010

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Role of CDK8 and β-catenin in colorectal adenocarcinoma

Jong-Og Seo, Song Iy Han, Sung-Chul Lim
Pages: 285-291
Published online on: 01 July 2010

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyv Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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