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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2010 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Rb family proteins in gastric cancer (Review)

Letizia Cito, Francesca Pentimalli, Iris Forte, Eliseo Mattioli, Antonio Giordano
Pages: 1411-1418
Published online on: 01 December 2010

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Article

Molecular targets for therapeutic interventions in human papillomavirus-related cancers (Review)

Alan Saito Ramalho, Anselmo Dantas Lopes, Aleylove Talans, Bruno Yoshihiro Parlato Sakiyama, Guilherme Luiz Stelko Pereira, Paulo Marcelo Hoff, Gilberto De Castro
Pages: 1419-1426
Published online on: 01 December 2010

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Article Open Access

Involvement of gicerin, a cell adhesion molecule, in the portal metastasis of rat colorectal adenocarcinoma cells

Kazuhide Adachi, Mahiro Hattori, Hidenori Kato, Marie Inai, Masaya Tsukamoto, Ekowati Handharyani, Eiichi Taira, Yasuhiro Tsukamoto
Pages: 1427-1431
Published online on: 01 December 2010

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Article Open Access

Evaluation of immune response according to the metastatic status in the regional lymph nodes in patients with gastric carcinoma

Keishi Nakamura, Itasu Ninomiya, Katsunobu Oyama, Masafumi Inokuchi, Shinichi Kinami, Sachio Fushida, Takashi Fujimura, Masato Kayahara, Tetsuo Ohta
Pages: 1433-1441
Published online on: 01 December 2010

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Article Open Access

Short GC-rich RNA similar to miR 1909 and 1915 folds in silico with the 5'-UTR and ORF of Notch and responders: Potential for the elimination of cancer stem cells

Yufeng Li, Takashi Mine, Constantin G. Ioannides
Pages: 1443-1453
Published online on: 01 December 2010

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Article

Cross-talk between NO and HMGB1 in lymphocytic thyroiditis and papillary thyroid cancer

Stefania Mardente, Alessandra Zicari, Fabrizio Consorti, Emanuela Mari, Maura Di Vito, Martina Leopizzi, Carlo Della Rocca, Alfredo Antonaci
Pages: 1455-1461
Published online on: 01 December 2010

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Article

Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death

Ryoko Asada, Katsuhiro Kageyama, Hiroshi Tanaka, Hisakazu Matsui, Masatsugu Kimura, Yasukazu Saitoh, Nobuhiko Miwa
Pages: 1463-1470
Published online on: 01 December 2010

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Article

Anthocyanins are novel AMPKα1 stimulators that suppress tumor growth by inhibiting mTOR phosphorylation

Yun-Kyoung Lee, Won Sup Lee, Gon Sup Kim, Ock Jin Park
Pages: 1471-1477
Published online on: 01 December 2010

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Article

GROα promotes invasion of colorectal cancer cells

Hideo Ogata, Akira Sekikawa, Hidetsugu Yamagishi, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Yuichi Ito, Masanori Fujita, Masahiro Tsubaki, Hiroyuki Kato, Takahiro Fujimori, Hirokazu Fukui
Pages: 1479-1486
Published online on: 01 December 2010

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Article

R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis

Takuya Inoue, Mitsuyuki Murano, Yukiko Yoda, Takanori Kuramoto, Kazuki Kakimoto, Kumi Ishida, Ken Kawakami, Yosuke Abe, Eijiro Morita, Naoko Murano, Satoshi Tokioka, Kentaro Maemura, Eiji Umegaki, Kazuhide Higuchi
Pages: 1487-1492
Published online on: 01 December 2010

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Article

Regulation of mutual inhibitory activities between AMPK and Akt with quercetin in MCF-7 breast cancer cells

Yun-Kyoung Lee, Ock Jin Park
Pages: 1493-1497
Published online on: 01 December 2010

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Article

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells

Seema-Maria Nathwani, Suzanne M. Cloonan, Maeve Stronach, Giuseppe Campiani, Mark Lawler, D. Clive Williams, Daniela M. Zisterer
Pages: 1499-1507
Published online on: 01 December 2010

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Article

Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts

Young-Soon Na, Seung-Mi Kim, Kyung-Ah Jung, Soo-Jin Yang, Yong Sang Hong, Min-Hee Ryu, Seonggu Ro, Dong-Hyung Cho, Jin Cheon Kim, Dong-Hoon Jin, Jung Shin Lee, Tae Won Kim
Pages: 1509-1514
Published online on: 01 December 2010

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Article

Effects of lysophosphatidic acid and its receptors LPA__AMB__frac13; on radiation pneumonitis

Jianxin Xue, Lu Gan, Xin Li, Jian Li, Guohai Qi, Yalan Wu, Xiaoyue Fu, Qing Mao, Rui Ao, Jingyi Lang, You Lu
Pages: 1515-1520
Published online on: 01 December 2010

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Article

Mitochondrial genotype and breast cancer predisposition

Anna M. Czarnecka, Tomasz Krawczyk, Katarzyna Plak, Aleksandra Klemba, Marek Zdrozny, Rebecca S. Arnold, Barbara Kofler, Pawel Golik, Aleksandra Szybinska, Jan Lubinski, Malgorzata Mossakowska, Ewa Bartnik, John A. Petros
Pages: 1521-1534
Published online on: 01 December 2010

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Article

Small bowel adenocarcinomas in celiac disease follow the CIM-MSI pathway

Frank Bergmann, Sandhya Singh, Sara Michel, Christoph Kahlert, Peter Schirmacher, Burkhard Helmke, Magnus Von Knebel Doeberitz, Matthias Kloor, Hendrik Bläker
Pages: 1535-1539
Published online on: 01 December 2010

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Article

Interaction between nuclear insulin receptor substrate-2 and NF-κB in IGF-1 induces response in breast cancer cells

Shufang Wu, Bo Zhou, Lin Xu, Hongzhi Sun
Pages: 1541-1550
Published online on: 01 December 2010

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Article

Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth

Yan Xue, Lei Li, Dong Zhang, Kaijie Wu, Peng Guo, Jin Zeng, Xinyang Wang, Dalin He
Pages: 1551-1559
Published online on: 01 December 2010

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Article

Tamoxifen-induced apoptosis of rat C6 glioma cells via PI3K/Akt, JNK and ERK activation

Ying Feng, Jintao Huang, Ying Ding, Fukang Xie, Xiaoyan Shen
Pages: 1561-1567
Published online on: 01 December 2010

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Article

Cytoplasmic and stromal expression of laminin γ 2 chain correlates with infiltrative invasion in ovarian mucinous neoplasms of gastro-intestinal type

Emi Okuma, Yoshihiro Ohishi, Yoshinao Oda, Shinichi Aishima, Shuichi Kurihara, Izumi Nishimura, Masafumi Yasunaga, Hiroaki Kobayashi, Norio Wake, Masazumi Tsuneyoshi
Pages: 1569-1576
Published online on: 01 December 2010

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Article

Expression of EphA1 in gastric carcinomas is associated with metastasis and survival

Jiandong Wang, Yingchun Dong, Xulin Wang, Henghui Ma, Zhen Sheng, Guli Li, Guangming Lu, Haruhiko Sugimura, Xiaojun Zhou
Pages: 1577-1584
Published online on: 01 December 2010

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Article

Allicin induces apoptosis in gastric cancer cells through activation of both extrinsic and intrinsic pathways

Wenlu Zhang, Minwen Ha, Yuehua Gong, Ying Xu, Nannan Dong, Yuan Yuan
Pages: 1585-1592
Published online on: 01 December 2010

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Article

The migration and invasion of human prostate cancer cell lines involves CD151 expression

Jian Ang, Bing-Liang Fang, Leonie K. Ashman, Albert G. Frauman
Pages: 1593-1597
Published online on: 01 December 2010

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Article

HPV-16 E6 upregulation of DNMT1 through repression of tumor suppressor p53

Chi Lam Au Yeung, Wing Pui Tsang, Tsun Yee Tsang, Ngai Na Co, Pak Lun Yau, Tim Tak Kwok
Pages: 1599-1604
Published online on: 01 December 2010

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Article

Adenovirus-mediated SOCS3 gene transfer inhibits the growth and enhances the radiosensitivity of human non-small cell lung cancer cells

Yu-Ching Lin, Chin-Kuo Lin, Ying-Huang Tsai, Hsu-Huei Weng, Ya-Chin Li, Liang You, Jan-Kan Chen, David M. Jablons, Cheng-Ta Yang
Pages: 1605-1612
Published online on: 01 December 2010

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Article

Synergistic gastric cancer inhibition by chemogenetherapy with recombinant human adenovirus p53 and epirubicin: an in vitro and in vivo study

Yi-Shan Xie, Yan-Hua Zhang, Shao-Ping Liu, Shi-Quan Liu, Chun-Wei Peng, Long Wu, He-Shen Luo, Yan Li
Pages: 1613-1620
Published online on: 01 December 2010

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Article

Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity

Koji Yamanegi, Junko Yamane, Kenta Kobayashi, Nahoko Kato-Kogoe, Hideki Ohyama, Keiji Nakasho, Naoko Yamada, Masaki Hata, Toshihiro Nishioka, Satoru Fukunaga, Hiroyuki Futani, Haruki Okamura, Nobuyuki Terada
Pages: 1621-1627
Published online on: 01 December 2010

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Article

Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity

Chia-Hung Hsieh, Cheng-Hung Lee, Ji-An Liang, Chun-Yen Yu, Woei-Cherng Shyu
Pages: 1629-1636
Published online on: 01 December 2010

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Article

Transforming growth factor β signaling inhibitor, SB-431542, induces maturation of dendritic cells and enhances anti-tumor activity

Hiroaki Tanaka, Osamu Shinto, Masakazu Yashiro, Sadaaki Yamazoe, Takehiko Iwauchi, Kazuya Muguruma, Naoshi Kubo, Masaichi Ohira, Kosei Hirakawa
Pages: 1637-1643
Published online on: 01 December 2010

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Article

An explorative study on the clinical utility of baseline and serial serum tumour marker measurements in advanced upper gastrointestinal cancer

P. Byström, Å Berglund, P. Nygren, L. Wernroth, B. Johansson, A. Larsson, R. Einarsson, B. Glimelius
Pages: 1645-1652
Published online on: 01 December 2010

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Article

Growth and differentiation factor-9 promotes adhesive and motile capacity of prostate cancer cells by up-regulating FAK and Paxillin via Smad dependent pathway Retraction in /10.3892/or.2026.9089

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Pages: 1653-1659
Published online on: 01 December 2010

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Article

BRCA1 and BRCA2 genetic test in high risk patients and families: counselling and management

Eleonora Marchina, Maria Grazia Fontana, Michela Speziani, Alessandro Salvi, Giuseppe Ricca, Diego Di Lorenzo, Maria Gervasi, Luigi Caimi, Sergio Barlati
Pages: 1661-1667
Published online on: 01 December 2010

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Article

The β-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor κB signaling

Xinhua Liao, Xiangming Che, Wei Zhao, Danjie Zhang, Tieqiang Bi, Guanghui Wang
Pages: 1669-1676
Published online on: 01 December 2010

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Article

Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest

Iwao Mikami, Fang Zhang, Tomomi Hirata, Junichi Okamoto, Kiyoshi Koizumi, Kazuo Shimizu, David Jablons, Biao He
Pages: 1677-1681
Published online on: 01 December 2010

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Article

Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation

Tao Zhang, Guang-Bin Cui, Jian Zhang, Feng Zhang, Yong-An Zhou, Tao Jiang, Xiao-Fei Li
Pages: 1683-1689
Published online on: 01 December 2010

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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