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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2010 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Rb family proteins in gastric cancer (Review)

Letizia Cito, Francesca Pentimalli, Iris Forte, Eliseo Mattioli, Antonio Giordano
Pages: 1411-1418
Published online on: 01 December 2010

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Article

Molecular targets for therapeutic interventions in human papillomavirus-related cancers (Review)

Alan Saito Ramalho, Anselmo Dantas Lopes, Aleylove Talans, Bruno Yoshihiro Parlato Sakiyama, Guilherme Luiz Stelko Pereira, Paulo Marcelo Hoff, Gilberto De Castro
Pages: 1419-1426
Published online on: 01 December 2010

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Article Open Access

Involvement of gicerin, a cell adhesion molecule, in the portal metastasis of rat colorectal adenocarcinoma cells

Kazuhide Adachi, Mahiro Hattori, Hidenori Kato, Marie Inai, Masaya Tsukamoto, Ekowati Handharyani, Eiichi Taira, Yasuhiro Tsukamoto
Pages: 1427-1431
Published online on: 01 December 2010

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Article Open Access

Evaluation of immune response according to the metastatic status in the regional lymph nodes in patients with gastric carcinoma

Keishi Nakamura, Itasu Ninomiya, Katsunobu Oyama, Masafumi Inokuchi, Shinichi Kinami, Sachio Fushida, Takashi Fujimura, Masato Kayahara, Tetsuo Ohta
Pages: 1433-1441
Published online on: 01 December 2010

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Article Open Access

Short GC-rich RNA similar to miR 1909 and 1915 folds in silico with the 5'-UTR and ORF of Notch and responders: Potential for the elimination of cancer stem cells

Yufeng Li, Takashi Mine, Constantin G. Ioannides
Pages: 1443-1453
Published online on: 01 December 2010

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Article

Cross-talk between NO and HMGB1 in lymphocytic thyroiditis and papillary thyroid cancer

Stefania Mardente, Alessandra Zicari, Fabrizio Consorti, Emanuela Mari, Maura Di Vito, Martina Leopizzi, Carlo Della Rocca, Alfredo Antonaci
Pages: 1455-1461
Published online on: 01 December 2010

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Article

Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death

Ryoko Asada, Katsuhiro Kageyama, Hiroshi Tanaka, Hisakazu Matsui, Masatsugu Kimura, Yasukazu Saitoh, Nobuhiko Miwa
Pages: 1463-1470
Published online on: 01 December 2010

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Article

Anthocyanins are novel AMPKα1 stimulators that suppress tumor growth by inhibiting mTOR phosphorylation

Yun-Kyoung Lee, Won Sup Lee, Gon Sup Kim, Ock Jin Park
Pages: 1471-1477
Published online on: 01 December 2010

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Article

GROα promotes invasion of colorectal cancer cells

Hideo Ogata, Akira Sekikawa, Hidetsugu Yamagishi, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Yuichi Ito, Masanori Fujita, Masahiro Tsubaki, Hiroyuki Kato, Takahiro Fujimori, Hirokazu Fukui
Pages: 1479-1486
Published online on: 01 December 2010

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Article

R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis

Takuya Inoue, Mitsuyuki Murano, Yukiko Yoda, Takanori Kuramoto, Kazuki Kakimoto, Kumi Ishida, Ken Kawakami, Yosuke Abe, Eijiro Morita, Naoko Murano, Satoshi Tokioka, Kentaro Maemura, Eiji Umegaki, Kazuhide Higuchi
Pages: 1487-1492
Published online on: 01 December 2010

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Article

Regulation of mutual inhibitory activities between AMPK and Akt with quercetin in MCF-7 breast cancer cells

Yun-Kyoung Lee, Ock Jin Park
Pages: 1493-1497
Published online on: 01 December 2010

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Article

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells

Seema-Maria Nathwani, Suzanne M. Cloonan, Maeve Stronach, Giuseppe Campiani, Mark Lawler, D. Clive Williams, Daniela M. Zisterer
Pages: 1499-1507
Published online on: 01 December 2010

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Article

Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts

Young-Soon Na, Seung-Mi Kim, Kyung-Ah Jung, Soo-Jin Yang, Yong Sang Hong, Min-Hee Ryu, Seonggu Ro, Dong-Hyung Cho, Jin Cheon Kim, Dong-Hoon Jin, Jung Shin Lee, Tae Won Kim
Pages: 1509-1514
Published online on: 01 December 2010

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Article

Effects of lysophosphatidic acid and its receptors LPA__AMB__frac13; on radiation pneumonitis

Jianxin Xue, Lu Gan, Xin Li, Jian Li, Guohai Qi, Yalan Wu, Xiaoyue Fu, Qing Mao, Rui Ao, Jingyi Lang, You Lu
Pages: 1515-1520
Published online on: 01 December 2010

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Article

Mitochondrial genotype and breast cancer predisposition

Anna M. Czarnecka, Tomasz Krawczyk, Katarzyna Plak, Aleksandra Klemba, Marek Zdrozny, Rebecca S. Arnold, Barbara Kofler, Pawel Golik, Aleksandra Szybinska, Jan Lubinski, Malgorzata Mossakowska, Ewa Bartnik, John A. Petros
Pages: 1521-1534
Published online on: 01 December 2010

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Article

Small bowel adenocarcinomas in celiac disease follow the CIM-MSI pathway

Frank Bergmann, Sandhya Singh, Sara Michel, Christoph Kahlert, Peter Schirmacher, Burkhard Helmke, Magnus Von Knebel Doeberitz, Matthias Kloor, Hendrik Bläker
Pages: 1535-1539
Published online on: 01 December 2010

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Article

Interaction between nuclear insulin receptor substrate-2 and NF-κB in IGF-1 induces response in breast cancer cells

Shufang Wu, Bo Zhou, Lin Xu, Hongzhi Sun
Pages: 1541-1550
Published online on: 01 December 2010

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Article

Telomerase suppression initiates PML-dependent p53 activation to inhibit bladder cancer cell growth

Yan Xue, Lei Li, Dong Zhang, Kaijie Wu, Peng Guo, Jin Zeng, Xinyang Wang, Dalin He
Pages: 1551-1559
Published online on: 01 December 2010

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Article

Tamoxifen-induced apoptosis of rat C6 glioma cells via PI3K/Akt, JNK and ERK activation

Ying Feng, Jintao Huang, Ying Ding, Fukang Xie, Xiaoyan Shen
Pages: 1561-1567
Published online on: 01 December 2010

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Article

Cytoplasmic and stromal expression of laminin γ 2 chain correlates with infiltrative invasion in ovarian mucinous neoplasms of gastro-intestinal type

Emi Okuma, Yoshihiro Ohishi, Yoshinao Oda, Shinichi Aishima, Shuichi Kurihara, Izumi Nishimura, Masafumi Yasunaga, Hiroaki Kobayashi, Norio Wake, Masazumi Tsuneyoshi
Pages: 1569-1576
Published online on: 01 December 2010

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Article

Expression of EphA1 in gastric carcinomas is associated with metastasis and survival

Jiandong Wang, Yingchun Dong, Xulin Wang, Henghui Ma, Zhen Sheng, Guli Li, Guangming Lu, Haruhiko Sugimura, Xiaojun Zhou
Pages: 1577-1584
Published online on: 01 December 2010

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Article

Allicin induces apoptosis in gastric cancer cells through activation of both extrinsic and intrinsic pathways

Wenlu Zhang, Minwen Ha, Yuehua Gong, Ying Xu, Nannan Dong, Yuan Yuan
Pages: 1585-1592
Published online on: 01 December 2010

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Article

The migration and invasion of human prostate cancer cell lines involves CD151 expression

Jian Ang, Bing-Liang Fang, Leonie K. Ashman, Albert G. Frauman
Pages: 1593-1597
Published online on: 01 December 2010

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Article

HPV-16 E6 upregulation of DNMT1 through repression of tumor suppressor p53

Chi Lam Au Yeung, Wing Pui Tsang, Tsun Yee Tsang, Ngai Na Co, Pak Lun Yau, Tim Tak Kwok
Pages: 1599-1604
Published online on: 01 December 2010

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Article

Adenovirus-mediated SOCS3 gene transfer inhibits the growth and enhances the radiosensitivity of human non-small cell lung cancer cells

Yu-Ching Lin, Chin-Kuo Lin, Ying-Huang Tsai, Hsu-Huei Weng, Ya-Chin Li, Liang You, Jan-Kan Chen, David M. Jablons, Cheng-Ta Yang
Pages: 1605-1612
Published online on: 01 December 2010

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Article

Synergistic gastric cancer inhibition by chemogenetherapy with recombinant human adenovirus p53 and epirubicin: an in vitro and in vivo study

Yi-Shan Xie, Yan-Hua Zhang, Shao-Ping Liu, Shi-Quan Liu, Chun-Wei Peng, Long Wu, He-Shen Luo, Yan Li
Pages: 1613-1620
Published online on: 01 December 2010

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Article

Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity

Koji Yamanegi, Junko Yamane, Kenta Kobayashi, Nahoko Kato-Kogoe, Hideki Ohyama, Keiji Nakasho, Naoko Yamada, Masaki Hata, Toshihiro Nishioka, Satoru Fukunaga, Hiroyuki Futani, Haruki Okamura, Nobuyuki Terada
Pages: 1621-1627
Published online on: 01 December 2010

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Article

Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity

Chia-Hung Hsieh, Cheng-Hung Lee, Ji-An Liang, Chun-Yen Yu, Woei-Cherng Shyu
Pages: 1629-1636
Published online on: 01 December 2010

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Article

Transforming growth factor β signaling inhibitor, SB-431542, induces maturation of dendritic cells and enhances anti-tumor activity

Hiroaki Tanaka, Osamu Shinto, Masakazu Yashiro, Sadaaki Yamazoe, Takehiko Iwauchi, Kazuya Muguruma, Naoshi Kubo, Masaichi Ohira, Kosei Hirakawa
Pages: 1637-1643
Published online on: 01 December 2010

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Article

An explorative study on the clinical utility of baseline and serial serum tumour marker measurements in advanced upper gastrointestinal cancer

P. Byström, Å Berglund, P. Nygren, L. Wernroth, B. Johansson, A. Larsson, R. Einarsson, B. Glimelius
Pages: 1645-1652
Published online on: 01 December 2010

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Article

Growth and differentiation factor-9 promotes adhesive and motile capacity of prostate cancer cells by up-regulating FAK and Paxillin via Smad dependent pathway

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Pages: 1653-1659
Published online on: 01 December 2010

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Article

BRCA1 and BRCA2 genetic test in high risk patients and families: counselling and management

Eleonora Marchina, Maria Grazia Fontana, Michela Speziani, Alessandro Salvi, Giuseppe Ricca, Diego Di Lorenzo, Maria Gervasi, Luigi Caimi, Sergio Barlati
Pages: 1661-1667
Published online on: 01 December 2010

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Article

The β-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor κB signaling

Xinhua Liao, Xiangming Che, Wei Zhao, Danjie Zhang, Tieqiang Bi, Guanghui Wang
Pages: 1669-1676
Published online on: 01 December 2010

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Article

Inhibition of activated phosphatidylinositol 3-kinase/AKT pathway in malignant pleural mesothelioma leads to G1 cell cycle arrest

Iwao Mikami, Fang Zhang, Tomomi Hirata, Junichi Okamoto, Kiyoshi Koizumi, Kazuo Shimizu, David Jablons, Biao He
Pages: 1677-1681
Published online on: 01 December 2010

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Article

Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation

Tao Zhang, Guang-Bin Cui, Jian Zhang, Feng Zhang, Yong-An Zhou, Tao Jiang, Xiao-Fei Li
Pages: 1683-1689
Published online on: 01 December 2010

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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