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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2012 Volume 27 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Molecular targeted therapies for cancer: Sorafenib mono­therapy and its combination with other therapies (Review)

Nuha Ibrahim, Yan Yu, William R. Walsh, Jia-Lin Yang
Pages: 1303-1311
Published online on: 06 February 2012

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Article Open Access

microRNA expression profile and differentially-expressed genes in prolactinomas following bromocriptine treatment

Chengde Wang, Zhipeng Su, Nader Sanai, Xiangyang Xue, Lijun Lu, Yunxiang Chen, Jinsen Wu, Weiming Zheng, Qichuan Zhuge, Zhe Bao Wu
Pages: 1312-1320
Published online on: 17 February 2012

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Article Open Access

Novel identification of the ETS-1 splice variants p42 and p27 in prostate cancer cell lines

David Adler, Jacqueline Ochsenfahrt, Kerstin Fuchs, Nicolas Wernert
Pages: 1321-1324
Published online on: 01 February 2012

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Article Open Access

Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer

Yoshifumi Nakayama, Masumi Yamauchi, Noritaka Minagawa, Takayuki Torigoe, Hiroto Izumi, Kimitoshi Kohno, Koji Yamaguchi
Pages: 1325-1330
Published online on: 16 January 2012

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Article Open Access

Whole blood RNA expression profiles in ovarian cancer patients with or without residual tumors after primary cytoreductive surgery

Helena S. Isaksson, Bengt Sorbe, Torbjörn K. Nilsson
Pages: 1331-1335
Published online on: 07 February 2012

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Article Open Access

Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations

Naoto Sato, Yasushi Saga, Hiroaki Mizukami, Dongdong Wang, Hiroyuki Fujiwara, Yuji Takei, Shizuo Machida, Keiya Ozawa, Mitsuaki Suzuki
Pages: 1336-1340
Published online on: 11 January 2012

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Article Open Access

Crotoxin enhances the antitumor activity of gefinitib (Iressa) in SK-MES-1 human lung squamous carcinoma cells

Jun-Hua Wang, Yan Xie, Jun-Chao Wu, Rong Han, Paul F. Reid, Zheng-Hong Qin, Jing-Kang He
Pages: 1341-1347
Published online on: 06 February 2012

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Article Open Access

CXCL12 mediates apoptosis resistance in rat C6 glioma cells

Kirsten Hattermann, Rolf Mentlein, Janka Held-Feindt
Pages: 1348-1352
Published online on: 06 February 2012

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Article Open Access

The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer

Haiping Chang, Jingzhi Wang, Yuan Tian, Jie Xu, Xiaojuan Gou, Jianxin Cheng
Pages: 1353-1359
Published online on: 01 February 2012

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Article

Plasmid DNA introduced into cultured cells with diagnostic ultrasound

Minoru Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida
Pages: 1360-1364
Published online on: 19 January 2012

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Article

Pre-neoplastic lesion, mucin-depleted foci, reveals de novo high-grade dysplasia in rat colon carcinogenesis

Changxu Cui, Reika Takamatsu, Hiroshi Doguchi, Akiko Matsuzaki, Masanao Saio, Naoki Yoshimi
Pages: 1365-1370
Published online on: 26 January 2012

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Article

Involvement of the mevalonate pathway in the antiproliferative effect of zoledronate on ACHN renal cell carcinoma cells

Megumi Fujita, Makiko Tohi, Kyoko Sawada, Yasuhiro Yamamoto, Tsutomu Nakamura, Tatsurou Yagami, Motohiro Yamamori, Noboru Okamura
Pages: 1371-1376
Published online on: 09 February 2012

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Article

Chemoembolization of unresectable hepatocellular carcinoma: Decreased toxicity with slow-release doxorubicin‑eluting beads compared with lipiodol

Francesco Recchia, Giovanni Passalacqua, Pietro Filauri, Marco Doddi, Pietro Boscarato, Giampiero Candeloro, Stefano Necozione, Giovambattista Desideri, Silvio Rea
Pages: 1377-1383
Published online on: 25 January 2012

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Article

Prognostic significance of PDCD4 expression and association with microRNA-21 in each Dukes' stage of colorectal cancer patients

Atsushi Horiuchi, Hisae Iinuma, Takuya Akahane, Ryu Shimada, Toshiaki Watanabe
Pages: 1384-1392
Published online on: 19 January 2012

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Article

Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients

Hiromichi Matsuoka, Tokuzo Arao, Chihiro Makimura, Masayuki Takeda, Hidemi Kiyota, Junji Tsurutani, Yoshihiko Fujita, Kazuko Matsumoto, Hideharu Kimura, Masatomo Otsuka, Atsuko Koyama, Chiyo K. Imamura, Yusuke Tanigawara, Takeharu Yamanaka, Kyoko Tanaka, Kazuto Nishio, Kazuhiko Nakagawa
Pages: 1393-1399
Published online on: 26 January 2012

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Article

Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers

Ronald A. Lubet, Margie L. Clapper, David L. McCormick, Michael A. Pereira, W-C. L. Chang, Vernon E. Steele, Susan M. Fischer, M. Margaret Juliana, Clinton J. Grubbs
Pages: 1400-1406
Published online on: 03 February 2012

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Article

Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells

Moo Rim Kang, Song-Kyu Park, Chang Woo Lee, Ig Jun Cho, Yeong Nang Jo, Jeong Wook Yang, Jin-Ah Kim, Jieun Yun, Ki Hoon Lee, Hyun Ju Kwon, Byung Woo Kim, Kiho Lee, Jong Soon Kang, Hwan Mook Kim
Pages: 1407-1412
Published online on: 19 January 2012

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Article

CRTC1-MAML2 gene fusion in mucoepidermoid carcinoma of the lacrimal gland

Sarah Linéa Von Holstein, André Fehr, Steffen Heegaard, Marianne Hamilton Therkildsen, Göran Stenman
Pages: 1413-1416
Published online on: 06 February 2012

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Article

Experimental chronic jet lag promotes growth and lung metastasis of Lewis lung carcinoma in C57BL/6 mice

Mingwei Wu, Jing Zeng, Yanfeng Chen, Zhaolei Zeng, Jinxin Zhang, Yuchen Cai, Yanli Ye, Liwu Fu, Lijian Xian, Zhongping Chen
Pages: 1417-1428
Published online on: 16 February 2012

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Article

High-resolution copy number array in the molecular cytogenetic diagnostics of pediatric malignant hematological disorders

Carina Wikhager, Inger Ögärd, Tommy Martinsson, Jonas Abrahamsson, Lars Palmqvist, Helene Sjögren
Pages: 1429-1434
Published online on: 16 February 2012

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Article

P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis

Liang-Hui Li, Qi Luo, Min-Hua Zheng, Chao Pan, Guo-Yang Wu, Yi-Zhuo Lu, Bo Feng, Xue-Hua Chen, Bing-Ya Liu
Pages: 1435-1442
Published online on: 27 January 2012

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Article

Antitumor effects of oncolytic adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase in colorectal cancer

Shuai Ma, Wenzhi Qu, Liang Mao, Zhi Zhu, Lanling Jia, Lei Zhao, Xinyu Zheng
Pages: 1443-1450
Published online on: 27 January 2012

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Article

Differential staining of γ synuclein in poorly differentiated compared to highly differentiated colon cancer cells

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer
Pages: 1451-1454
Published online on: 26 January 2012

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Article

Chlorophyllin e4 is a novel photosensitizer against human bladder cancer cells

Bin Li, Zhiming Wu, Wenzhi Li, Guojin Jia, Jiancheng Lu, Jie Fang, Gang Chen
Pages: 1455-1460
Published online on: 26 January 2012

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Article

Effect of inhibition of the adrenomedullin gene on the growth and chemosensitivity of ovarian cancer cells

Pan Chen, Xiaoyan Pang, Yi Zhang, Yunqin He
Pages: 1461-1466
Published online on: 26 January 2012

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Article

Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway

Ji Cheon Jeong, Saeng Jae Kim, Yong Keun Kim, Chae Hwa Kwon, Ki Hyung Kim
Pages: 1467-1474
Published online on: 16 January 2012

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Article

Natural history of human aberrant crypt foci and correlation with risk factors for colorectal cancer

Hidenori Ohkubo, Hirokazu Takahashi, Eiji Yamada, Eiji Sakai, Takuma Higurashi, Takashi Uchiyama, Kunihiro Hosono, Hiroki Endo, Masataka Taguri, Atsushi Nakajima
Pages: 1475-1480
Published online on: 12 January 2012

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Article

Cytotoxic effect of evodiamine in SGC-7901 human gastric adenocarcinoma cells via simultaneous induction of apoptosis and autophagy

Azhar Rasul, Bo Yu, Lili Zhong, Muhammad Khan, Hong Yang, Tonghui Ma
Pages: 1481-1487
Published online on: 21 February 2012

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Article

Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells

Xiaomei Wu, Qin Yan, Zhenbo Zhang, Guiqiang Du, Xiaoping Wan
Pages: 1488-1496
Published online on: 02 February 2012

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Article

Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells

Lihua Liu, Jun Meng, Cong Zhang, Yuqing Duan, Lianmei Zhao, Shijie Wang, Baoen Shan
Pages: 1497-1503
Published online on: 27 January 2012

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Article

miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells

Jianwei Hao, Chunzhi Zhang, Anlin Zhang, Kun Wang, Zhifan Jia, Guangxiu Wang, Lei Han, Chunsheng Kang, Peiyu Pu
Pages: 1504-1510
Published online on: 26 January 2012

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Article

Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo

Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen
Pages: 1511-1519
Published online on: 09 January 2012

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Article

Metadherin regulates radioresistance in cervical cancer cells

Ying Zhao, Meena S. Moran, Qifeng Yang, Qiao Liu, Cunzhong Yuan, Shuhui Hong, Beihua Kong
Pages: 1520-1526
Published online on: 20 February 2012

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Article

NF-κB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IκBα pathway

Gen Lin, Zhiwei Tang, Yun-Bin Ye, Qiang Chen
Pages: 1527-1534
Published online on: 02 February 2012

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Article

Mitochondrial localization of P-glycoprotein in the human breast cancer cell line MCF-7/ADM and its functional characterization

Yi Shen, Yan Chu, Yan Yang, Zehua Wang
Pages: 1535-1540
Published online on: 02 February 2012

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Article

Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines

Xue-Feng Huang, Jie Han, Xiao-Tong Hu, Chao He
Pages: 1541-1547
Published online on: 03 February 2012

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Article

Silencing TRPC1 expression inhibits invasion of CNE2 nasopharyngeal tumor cells

Benfu He, Feiye Liu, Jian Ruan, Aimin Li, Jinzhang Chen, Rong Li, Jie Shen, Dayong Zheng, Rongcheng Luo
Pages: 1548-1554
Published online on: 22 February 2012

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Article

Novel mutations of the HRAS gene and absence of hotspot mutations of the BRAF genes in oral squamous cell carcinoma in a Greek population

Dimitra Koumaki, George Kostakis, Vasiliki Koumaki, Nikolaos Papadogeorgakis, Michael Makris, Alexandros Katoulis, Smaragda Kamakari, George Koutsodontis, Christos Perisanidis, Vaia Lambadiari, Evanthia Chrysomali, Nikolaos Stavrianeas, Constantinos Alexandridis, Dimitrios Rigopoulos
Pages: 1555-1560
Published online on: 26 January 2012

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Article

Fasudil inhibits lung carcinoma-conditioned endothelial cell viability and migration

Zhe Zhang, Jing-Hua Ren, Zhen-Yu Li, Li Nong, Gang Wu
Pages: 1561-1566
Published online on: 14 February 2012

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Article

Inhibitory effects of epigallocatechin-3-gallate on cell proliferation and the expression of HIF-1α and P-gp in the human pancreatic carcinoma cell line PANC-1

Zhenni Zhu, Yu Wang, Zhiqing Liu, Fan Wang, Qiu Zhao
Pages: 1567-1572
Published online on: 22 February 2012

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Article

Increased basic fibroblast growth factor release and proliferation in xenotransplanted squamous cell carcinoma after combined irradiation/anti-vascular endothelial growth factor treatment

Kai Fruth, Stefan Weber, Yunus Okcu, Ruediger Noppens, Klaus U. Klein, Eva Joest, Jana Hedrich, Sebastian Thilemann, Benjamin Pogorzelski, Dimitrios Koutsimpelas, Stefan Fischer, Kerstin Muennemann, Annette Affolter, Ulf R. Heinrich, Christoph Brochhausen, Irene Schmidtmann, Wolf J. Mann, Heinz Schmidberger, Laura M. Schreiber, Juergen Brieger
Pages: 1573-1579
Published online on: 26 January 2012

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Article

Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy

Charles C.L. Tong, K. H. Vincent Lau, Michael Rivera, David Cannan, Julio Aguirre-Ghiso, Andrew G. Sikora, Vishal Gupta, Kevin Forsythe, Eric C. Ko, Krzysztof Misiukiewicz, Vivek Gurudutt, Marita S. Teng, Stuart H. Packer, Eric M. Genden, Johnny Kao
Pages: 1580-1586
Published online on: 07 February 2012

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Article

SNAI1 overexpression induces stemness and promotes ovarian cancer cell invasion and metastasis

Zhen-Yu Lu, Rong Dong, Dong Li, Wen-Bo Li, Feng-Qin Xu, Ying Geng, Yun-Shan Zhang
Pages: 1587-1591
Published online on: 13 February 2012

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Article

Nestin expression in high-grade osteosarcomas and its clinical significance

Iva Zambo, Marketa Hermanova, Dagmar Adamkova Krakorova, Peter Mudry, Karel Zitterbart, Michal Kyr, Karel Vesely, Jaroslav Sterba, Renata Veselska
Pages: 1592-1598
Published online on: 14 February 2012

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Article

Epithelial mesenchymal transition correlates with CD24+CD44+ and CD133+ cells in pancreatic cancer

Ye Zhang, Jishu Wei, Hui Wang, Xiaofeng Xue, Yong An, Dong Tang, Zhongxu Yuan, Feitong Wang, Junli Wu, Jingjing Zhang, Yi Miao
Pages: 1599-1605
Published online on: 07 February 2012

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Article

Characteristic CYP2A6 genetic polymorphisms detected by TA cloning-based sequencing in Chinese digestive system cancer patients with S-1 based chemotherapy

Wei-Jia Fang, Hai-Bo Mou, Da-Zhi Jin, Yu-Long Zheng, Peng Zhao, Chen-Yu Mao, Ling Peng, Ming-Zhu Huang, Nong Xu
Pages: 1606-1610
Published online on: 07 February 2012

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Article

MAPK inhibitors and siRNAs differentially affect cell death and ROS levels in arsenic trioxide-treated human pulmonary fibroblast cells

Woo Hyun Park
Pages: 1611-1618
Published online on: 27 January 2012

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Article

Cinobufocini inhibits NF-κB and COX-2 activation induced by TNF-α in lung adenocarcinoma cells

Ju-Yong Wang, Ling Chen, Zhan Zheng, Qing Wang, Jing Guo, Ling Xu
Pages: 1619-1624
Published online on: 19 January 2012

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Article

Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer

Helena J. Mauceri, Harold G. Sutton, Thomas E. Darga, Masha Kocherginsky, Joel Kochanski, Ralph R. Weichselbaum, Everett E. Vokes
Pages: 1625-1629
Published online on: 27 January 2012

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Article

Association of aberrant DNA methylation with clinicopathological features in breast cancer

Aggeliki Tserga, Nicolaos V. Michalopoulos, Georgia Levidou, Penelope Korkolopoulou, George Zografos, Efstratios Patsouris, Angelica A. Saetta
Pages: 1630-1638
Published online on: 05 December 2011

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Article

Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma

Xiao-Fang Guo, Xiao-Fei Zhu, Gen-Shen Zhong, Bao-Guo Deng, Zhi-Tao Gao, Hui Wang
Pages: 1639-1645
Published online on: 26 January 2012

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Article

RACK1 downregulation suppresses migration and proliferation of neuroblastoma cell lines

Fan Lu, Chi Zhang, Wen-Jie Wu, Ye-Ming Wu
Pages: 1646-1652
Published online on: 11 January 2012

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Article

Decreased expression of repulsive guidance molecule member A by DNA methylation in colorectal cancer is related to tumor progression

Zhi-Wei Zhao, Wen-Jing Lian, Guo-Qing Chen, Hong-Ying Zhou, Gui-Ming Wang, Xia Cao, Hui-Jun Yang, Yi-Ping Hou
Pages: 1653-1659
Published online on: 20 February 2012

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Article

miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma

Qin Zhu, Zhiming Wang, Yu Hu, Jindong Li, Xinying Li, Ledu Zhou, Yun Huang
Pages: 1660-1668
Published online on: 09 February 2012

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Article

3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest

Seo Ju Kim, Ju-Seog Lee, Soo Mi Kim
Pages: 1669-1673
Published online on: 27 January 2012

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Article

Downregulation of midkine induces cisplatin resistance in human oral squamous cell carcinoma

Tomoko Ota, Hirofumi Jono, Kazutoshi Ota, Satoru Shinriki, Mitsuharu Ueda, Takanao Sueyoshi, Ken Nakatani, Yukihiro Hiraishi, Takeshi Wada, Shigeyuki Fujita, Konen Obayashi, Masanori Shinohara, Yukio Ando
Pages: 1674-1680
Published online on: 13 February 2012

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Article

Genome-wide identification of OTP gene as a novel methylation marker of breast cancer

Myung Soon Kim, Jinsun Lee, Taejeong Oh, Youngho Moon, Eilsung Chang, Kwang Sun Seo, Benjamin Douglas Hoehn, Sungwhan An, Jeung-Hoon Lee
Pages: 1681-1688
Published online on: 17 February 2012

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Article

Inhibition of neuroblastoma cell growth by TREX1-mutated human lymphocytes

A. Pulliero, B. Marengo, C. Domenicotti, M. G. Longobardi, E. Fazzi, S. Orcesi, M. Bianchi, U. Balottin, A. Izzotti
Pages: 1689-1694
Published online on: 22 February 2012

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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