Journal Articles

Molecular targeted therapies for cancer: Sorafenib mono­therapy and its combination with other therapies (Review)

Nuha Ibrahim, Yan Yu, William R. Walsh, Jia-Lin Yang

Pages: 1303-1311 Published online on: 06 February 2012
Open Access

microRNA expression profile and differentially-expressed genes in prolactinomas following bromocriptine treatment

Chengde Wang, Zhipeng Su, Nader Sanai, Xiangyang Xue, Lijun Lu, Yunxiang Chen, Jinsen Wu, Weiming Zheng, Qichuan Zhuge, Zhe Bao Wu

Pages: 1312-1320 Published online on: 17 February 2012
Open Access

Novel identification of the ETS-1 splice variants p42 and p27 in prostate cancer cell lines

Zaki Shaikhibrahim, Jacqueline Ochsenfahrt, Kerstin Fuchs, Nicolas Wernert

Pages: 1321-1324 Published online on: 01 February 2012
Open Access

Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer

Yoshifumi Nakayama, Masumi Yamauchi, Noritaka Minagawa, Takayuki Torigoe, Hiroto Izumi, Kimitoshi Kohno, Koji Yamaguchi

Pages: 1325-1330 Published online on: 16 January 2012
Open Access

Whole blood RNA expression profiles in ovarian cancer patients with or without residual tumors after primary cytoreductive surgery

Helena S. Isaksson, Bengt Sorbe, Torbjörn K. Nilsson

Pages: 1331-1335 Published online on: 07 February 2012
Open Access

Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations

Naoto Sato, Yasushi Saga, Hiroaki Mizukami, Dongdong Wang, Hiroyuki Fujiwara, Yuji Takei, Shizuo Machida, Keiya Ozawa, Mitsuaki Suzuki

Pages: 1336-1340 Published online on: 11 January 2012
Open Access

Crotoxin enhances the antitumor activity of gefinitib (Iressa) in SK-MES-1 human lung squamous carcinoma cells

Jun-Hua Wang, Yan Xie, Jun-Chao Wu, Rong Han, Paul F. Reid, Zheng-Hong Qin, Jing-Kang He

Pages: 1341-1347 Published online on: 06 February 2012
Open Access

CXCL12 mediates apoptosis resistance in rat C6 glioma cells

Kirsten Hattermann, Rolf Mentlein, Janka Held-Feindt

Pages: 1348-1352 Published online on: 06 February 2012
Open Access

The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer

Haiping Chang, Jingzhi Wang, Yuan Tian, Jie Xu, Xiaojuan Gou, Jianxin Cheng

Pages: 1353-1359 Published online on: 01 February 2012

Plasmid DNA introduced into cultured cells with diagnostic ultrasound

Minoru Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida

Pages: 1360-1364 Published online on: 19 January 2012

Pre-neoplastic lesion, mucin-depleted foci, reveals de novo high-grade dysplasia in rat colon carcinogenesis

Changxu Cui, Reika Takamatsu, Hiroshi Doguchi, Akiko Matsuzaki, Masanao Saio, Naoki Yoshimi

Pages: 1365-1370 Published online on: 26 January 2012

Involvement of the mevalonate pathway in the antiproliferative effect of zoledronate on ACHN renal cell carcinoma cells

Megumi Fujita, Makiko Tohi, Kyoko Sawada, Yasuhiro Yamamoto, Tsutomu Nakamura, Tatsurou Yagami, Motohiro Yamamori, Noboru Okamura

Pages: 1371-1376 Published online on: 09 February 2012

Chemoembolization of unresectable hepatocellular carcinoma: Decreased toxicity with slow-release doxorubicin‑eluting beads compared with lipiodol

Francesco Recchia, Giovanni Passalacqua, Pietro Filauri, Marco Doddi, Pietro Boscarato, Giampiero Candeloro, Stefano Necozione, Giovambattista Desideri, Silvio Rea

Pages: 1377-1383 Published online on: 25 January 2012

Prognostic significance of PDCD4 expression and association with microRNA-21 in each Dukes' stage of colorectal cancer patients

Atsushi Horiuchi, Hisae Iinuma, Takuya Akahane, Ryu Shimada, Toshiaki Watanabe

Pages: 1384-1392 Published online on: 19 January 2012

Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients

Hiromichi Matsuoka, Tokuzo Arao, Chihiro Makimura, Masayuki Takeda, Hidemi Kiyota, Junji Tsurutani, Yoshihiko Fujita, Kazuko Matsumoto, Hideharu Kimura, Masatomo Otsuka, Atsuko Koyama, Chiyo K. Imamura, Yusuke Tanigawara, Takeharu Yamanaka, Kyoko Tanaka, Kazuto Nishio, Kazuhiko Nakagawa

Pages: 1393-1399 Published online on: 26 January 2012

Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers

Ronald A. Lubet, Margie L. Clapper, David L. McCormick, Michael A. Pereira, W-C. L. Chang, Vernon E. Steele, Susan M. Fischer, M. Margaret Juliana, Clinton J. Grubbs

Pages: 1400-1406 Published online on: 03 February 2012

Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells

Moo Rim Kang, Song-Kyu Park, Chang Woo Lee, Ig Jun Cho, Yeong Nang Jo, Jeong Wook Yang, Jin-Ah Kim, Jieun Yun, Ki Hoon Lee, Hyun Ju Kwon, Byung Woo Kim, Kiho Lee, Jong Soon Kang, Hwan Mook Kim

Pages: 1407-1412 Published online on: 19 January 2012

CRTC1-MAML2 gene fusion in mucoepidermoid carcinoma of the lacrimal gland

Sarah Linéa Von Holstein, André Fehr, Steffen Heegaard, Marianne Hamilton Therkildsen, Göran Stenman

Pages: 1413-1416 Published online on: 06 February 2012

Experimental chronic jet lag promotes growth and lung metastasis of Lewis lung carcinoma in C57BL/6 mice

Mingwei Wu, Jing Zeng, Yanfeng Chen, Zhaolei Zeng, Jinxin Zhang, Yuchen Cai, Yanli Ye, Liwu Fu, Lijian Xian, Zhongping Chen

Pages: 1417-1428 Published online on: 16 February 2012

High-resolution copy number array in the molecular cytogenetic diagnostics of pediatric malignant hematological disorders

Carina Wikhager, Inger Ögärd, Tommy Martinsson, Jonas Abrahamsson, Lars Palmqvist, Helene Sjögren

Pages: 1429-1434 Published online on: 16 February 2012

P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis

Liang-Hui Li, Qi Luo, Min-Hua Zheng, Chao Pan, Guo-Yang Wu, Yi-Zhuo Lu, Bo Feng, Xue-Hua Chen, Bing-Ya Liu

Pages: 1435-1442 Published online on: 27 January 2012

Antitumor effects of oncolytic adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase in colorectal cancer

Shuai Ma, Wenzhi Qu, Liang Mao, Zhi Zhu, Lanling Jia, Lei Zhao, Xinyu Zheng

Pages: 1443-1450 Published online on: 27 January 2012

Differential staining of γ synuclein in poorly differentiated compared to highly differentiated colon cancer cells

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer

Pages: 1451-1454 Published online on: 26 January 2012

Chlorophyllin e4 is a novel photosensitizer against human bladder cancer cells

Bin Li, Zhiming Wu, Wenzhi Li, Guojin Jia, Jiancheng Lu, Jie Fang, Gang Chen

Pages: 1455-1460 Published online on: 26 January 2012

Effect of inhibition of the adrenomedullin gene on the growth and chemosensitivity of ovarian cancer cells

Pan Chen, Xiaoyan Pang, Yi Zhang, Yunqin He

Pages: 1461-1466 Published online on: 26 January 2012

Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway

Ji Cheon Jeong, Saeng Jae Kim, Yong Keun Kim, Chae Hwa Kwon, Ki Hyung Kim

Pages: 1467-1474 Published online on: 16 January 2012

Natural history of human aberrant crypt foci and correlation with risk factors for colorectal cancer

Hidenori Ohkubo, Hirokazu Takahashi, Eiji Yamada, Eiji Sakai, Takuma Higurashi, Takashi Uchiyama, Kunihiro Hosono, Hiroki Endo, Masataka Taguri, Atsushi Nakajima

Pages: 1475-1480 Published online on: 12 January 2012

Cytotoxic effect of evodiamine in SGC-7901 human gastric adenocarcinoma cells via simultaneous induction of apoptosis and autophagy

Azhar Rasul, Bo Yu, Lili Zhong, Muhammad Khan, Hong Yang, Tonghui Ma

Pages: 1481-1487 Published online on: 21 February 2012

Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells

Xiaomei Wu, Qin Yan, Zhenbo Zhang, Guiqiang Du, Xiaoping Wan

Pages: 1488-1496 Published online on: 02 February 2012

Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells

Lihua Liu, Jun Meng, Cong Zhang, Yuqing Duan, Lianmei Zhao, Shijie Wang, Baoen Shan

Pages: 1497-1503 Published online on: 27 January 2012

miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells

Jianwei Hao, Chunzhi Zhang, Anlin Zhang, Kun Wang, Zhifan Jia, Guangxiu Wang, Lei Han, Chunsheng Kang, Peiyu Pu

Pages: 1504-1510 Published online on: 26 January 2012

Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo

Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen

Pages: 1511-1519 Published online on: 09 January 2012

Metadherin regulates radioresistance in cervical cancer cells

Ying Zhao, Meena S. Moran, Qifeng Yang, Qiao Liu, Cunzhong Yuan, Shuhui Hong, Beihua Kong

Pages: 1520-1526 Published online on: 20 February 2012

NF-κB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IκBα pathway

Gen Lin, Zhiwei Tang, Yun-Bin Ye, Qiang Chen

Pages: 1527-1534 Published online on: 02 February 2012

Mitochondrial localization of P-glycoprotein in the human breast cancer cell line MCF-7/ADM and its functional characterization

Yi Shen, Yan Chu, Yan Yang, Zehua Wang

Pages: 1535-1540 Published online on: 02 February 2012

Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines

Xue-Feng Huang, Jie Han, Xiao-Tong Hu, Chao He

Pages: 1541-1547 Published online on: 03 February 2012

Silencing TRPC1 expression inhibits invasion of CNE2 nasopharyngeal tumor cells

Benfu He, Feiye Liu, Jian Ruan, Aimin Li, Jinzhang Chen, Rong Li, Jie Shen, Dayong Zheng, Rongcheng Luo

Pages: 1548-1554 Published online on: 22 February 2012

Novel mutations of the HRAS gene and absence of hotspot mutations of the BRAF genes in oral squamous cell carcinoma in a Greek population

Dimitra Koumaki, George Kostakis, Vasiliki Koumaki, Nikolaos Papadogeorgakis, Michael Makris, Alexandros Katoulis, Smaragda Kamakari, George Koutsodontis, Christos Perisanidis, Vaia Lambadiari, Evanthia Chrysomali, Nikolaos Stavrianeas, Constantinos Alexandridis, Dimitrios Rigopoulos

Pages: 1555-1560 Published online on: 26 January 2012

Fasudil inhibits lung carcinoma-conditioned endothelial cell viability and migration

Zhe Zhang, Jing-Hua Ren, Zhen-Yu Li, Li Nong, Gang Wu

Pages: 1561-1566 Published online on: 14 February 2012

Inhibitory effects of epigallocatechin-3-gallate on cell proliferation and the expression of HIF-1α and P-gp in the human pancreatic carcinoma cell line PANC-1

Zhenni Zhu, Yu Wang, Zhiqing Liu, Fan Wang, Qiu Zhao

Pages: 1567-1572 Published online on: 22 February 2012

Increased basic fibroblast growth factor release and proliferation in xenotransplanted squamous cell carcinoma after combined irradiation/anti-vascular endothelial growth factor treatment

Kai Fruth, Stefan Weber, Yunus Okcu, Ruediger Noppens, Klaus U. Klein, Eva Joest, Jana Hedrich, Sebastian Thilemann, Benjamin Pogorzelski, Dimitrios Koutsimpelas, Stefan Fischer, Kerstin Muennemann, Annette Affolter, Ulf R. Heinrich, Christoph Brochhausen, Irene Schmidtmann, Wolf J. Mann, Heinz Schmidberger, Laura M. Schreiber, Juergen Brieger

Pages: 1573-1579 Published online on: 26 January 2012

Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy

Charles C.L. Tong, K. H. Vincent Lau, Michael Rivera, David Cannan, Julio Aguirre-Ghiso, Andrew G. Sikora, Vishal Gupta, Kevin Forsythe, Eric C. Ko, Krzysztof Misiukiewicz, Vivek Gurudutt, Marita S. Teng, Stuart H. Packer, Eric M. Genden, Johnny Kao

Pages: 1580-1586 Published online on: 07 February 2012

SNAI1 overexpression induces stemness and promotes ovarian cancer cell invasion and metastasis

Zhen-Yu Lu, Rong Dong, Dong Li, Wen-Bo Li, Feng-Qin Xu, Ying Geng, Yun-Shan Zhang

Pages: 1587-1591 Published online on: 13 February 2012

Nestin expression in high-grade osteosarcomas and its clinical significance

Iva Zambo, Marketa Hermanova, Dagmar Adamkova Krakorova, Peter Mudry, Karel Zitterbart, Michal Kyr, Karel Vesely, Jaroslav Sterba, Renata Veselska

Pages: 1592-1598 Published online on: 14 February 2012

Epithelial mesenchymal transition correlates with CD24+CD44+ and CD133+ cells in pancreatic cancer

Ye Zhang, Jishu Wei, Hui Wang, Xiaofeng Xue, Yong An, Dong Tang, Zhongxu Yuan, Feitong Wang, Junli Wu, Jingjing Zhang, Yi Miao

Pages: 1599-1605 Published online on: 07 February 2012

Characteristic CYP2A6 genetic polymorphisms detected by TA cloning-based sequencing in Chinese digestive system cancer patients with S-1 based chemotherapy

Wei-Jia Fang, Hai-Bo Mou, Da-Zhi Jin, Yu-Long Zheng, Peng Zhao, Chen-Yu Mao, Ling Peng, Ming-Zhu Huang, Nong Xu

Pages: 1606-1610 Published online on: 07 February 2012

Cinobufocini inhibits NF-κB and COX-2 activation induced by TNF-α in lung adenocarcinoma cells

Ju-Yong Wang, Ling Chen, Zhan Zheng, Qing Wang, Jing Guo, Ling Xu

Pages: 1619-1624 Published online on: 19 January 2012

Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer

Helena J. Mauceri, Harold G. Sutton, Thomas E. Darga, Masha Kocherginsky, Joel Kochanski, Ralph R. Weichselbaum, Everett E. Vokes

Pages: 1625-1629 Published online on: 27 January 2012

Association of aberrant DNA methylation with clinicopathological features in breast cancer

Aggeliki Tserga, Nicolaos V. Michalopoulos, Georgia Levidou, Penelope Korkolopoulou, George Zografos, Efstratios Patsouris, Angelica A. Saetta

Pages: 1630-1638 Published online on: 05 December 2011

Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma

Xiao-Fang Guo, Xiao-Fei Zhu, Gen-Shen Zhong, Bao-Guo Deng, Zhi-Tao Gao, Hui Wang

Pages: 1639-1645 Published online on: 26 January 2012

RACK1 downregulation suppresses migration and proliferation of neuroblastoma cell lines

Fan Lu, Chi Zhang, Wen-Jie Wu, Ye-Ming Wu

Pages: 1646-1652 Published online on: 11 January 2012

Decreased expression of repulsive guidance molecule member A by DNA methylation in colorectal cancer is related to tumor progression

Zhi-Wei Zhao, Wen-Jing Lian, Guo-Qing Chen, Hong-Ying Zhou, Gui-Ming Wang, Xia Cao, Hui-Jun Yang, Yi-Ping Hou

Pages: 1653-1659 Published online on: 20 February 2012

miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma

Qin Zhu, Zhiming Wang, Yu Hu, Jindong Li, Xinying Li, Ledu Zhou, Yun Huang

Pages: 1660-1668 Published online on: 09 February 2012

3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest

Seo Ju Kim, Ju-Seog Lee, Soo Mi Kim

Pages: 1669-1673 Published online on: 27 January 2012

Downregulation of midkine induces cisplatin resistance in human oral squamous cell carcinoma

Tomoko Ota, Hirofumi Jono, Kazutoshi Ota, Satoru Shinriki, Mitsuharu Ueda, Takanao Sueyoshi, Ken Nakatani, Yukihiro Hiraishi, Takeshi Wada, Shigeyuki Fujita, Konen Obayashi, Masanori Shinohara, Yukio Ando

Pages: 1674-1680 Published online on: 13 February 2012

Genome-wide identification of OTP gene as a novel methylation marker of breast cancer

Myung Soon Kim, Jinsun Lee, Taejeong Oh, Youngho Moon, Eilsung Chang, Kwang Sun Seo, Benjamin Douglas Hoehn, Sungwhan An, Jeung-Hoon Lee

Pages: 1681-1688 Published online on: 17 February 2012

Inhibition of neuroblastoma cell growth by TREX1-mutated human lymphocytes

A. Pulliero, B. Marengo, C. Domenicotti, M. G. Longobardi, E. Fazzi, S. Orcesi, M. Bianchi, U. Balottin, A. Izzotti

Pages: 1689-1694 Published online on: 22 February 2012
Journal Cover

May 2012
Volume 27 Issue 5

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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