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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2022 Volume 24 Issue 4

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Article

A retrospective study on the relationship between fibrosis‑4 index and all‑cause mortality in patients with acute myocardial infarction

Maolin Cao, Tingming Li, Zhifeng Li, Fang Gong, Zijun Chen
Article Number: 643
Published online on: 31 August 2022

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Increased TIGIT+PD‑1+CXCR5‑CD4+T cells are associated with disease activity in rheumatoid arthritis

Qing Luo, Peng Fu, Yongqin Guo, Biqi Fu, Yang Guo, Qingshui Huang, Zikun Huang, Junming Li
Article Number: 642
Published online on: 31 August 2022

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A rare rectal gastrointestinal stromal tumor with indolent biological behavior: A case study

Jian Yang, Ying Liu, Xue-Jia Sun, Zhong-Wei Ai, Shi Liu
Article Number: 641
Published online on: 30 August 2022

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Review Open Access

Macrophages in melanoma: A double‑edged sword and targeted therapy strategies (Review)

Qiujun Zhou, Tingting Fang, Shenyu Wei, Shiqian Chai, Huifeng Yang, Maocan Tao, Yi Cao
Article Number: 640
Published online on: 26 August 2022

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1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways

Dong Wang, Yan Li, Liheng Dai, Yanxia Wang, Congna Zhao, Wangang Wang, Yu Zhang, Yinrui Zhao, Tingting Yu
Article Number: 639
Published online on: 26 August 2022

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HuR affects chemoresistance of small cell lung cancer by regulating FGFRL1 expression

Xun-Huang Duan, Rui Chen, Dao-Sheng Li, Ai-Hua Luo, Lin-Lang Guo
Article Number: 638
Published online on: 24 August 2022

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Reverse shoulder arthroplasty vs. hemiarthroplasty for the treatment of osteoporotic proximal humeral fractures in elderly patients: A systematic review and meta‑analysis update

Peng-Fei Han, Su Yang, Yue-Peng Wang, Xue-Dong Hou, Yuan Li, Xi-Yong Li
Article Number: 637
Published online on: 24 August 2022

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Metformin suppresses foam cell formation, inflammation and ferroptosis via the AMPK/ERK signaling pathway in ox‑LDL‑induced THP‑1 monocytes

Yihan Zhao, Yizhen Zhao, Yuan Tian, Yang Zhou
Article Number: 636
Published online on: 24 August 2022

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Effects of Brain Factor‑7® against motor deficit and oxidative stress in a mouse model of MPTP‑induced Parkinson's disease

Tae-Kyeong Lee, Jae-Chul Lee, Dae Won Kim, Ji-Won Lee, Sung-Su Kim, Hyung-Il Kim, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won, Soo Young Choi
Article Number: 635
Published online on: 24 August 2022

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mRNA and lncRNA expression profiles of liver tissues in children with biliary atresia

Wenyan Wu, Weifang Wu, Yongqin Ye, Tao Li, Bin Wang
Article Number: 634
Published online on: 22 August 2022

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Therapeutic effect of autologous bone marrow cells injected into the liver under the guidance of B‑ultrasound in the treatment of HBV‑related decompensated liver cirrhosis

Lei Li, Yanhui Si, Mingrong Cheng, Lin Lang, Aijun Li, Baochi Liu
Article Number: 633
Published online on: 22 August 2022

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Citrulline protects against LPS‑induced acute lung injury by inhibiting ROS/NLRP3‑dependent pyroptosis and apoptosis via the Nrf2 signaling pathway

Yao Xue, Yunqian Zhang, Li Chen, Yan Wang, Zhou Lv, Li-Qiao Yang, Siyuan Li
Article Number: 632
Published online on: 22 August 2022

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Case Report Open Access

Mediastinal cavernous angioleiomyoma: A case report and review of literature

Zhibo Zuo, Wanxin Wu, Xin Li, Lin Zhang, Jingyu Wang, Zhiqin Guo, Shaoqing Hu, Qi Zhang
Article Number: 631
Published online on: 22 August 2022

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Article Open Access

Propofol produces neurotoxicity by inducing mitochondrial apoptosis

Yubing Liang, Yu Huang, Rongge Shao, Fei Xiao, Fei Lin, Huijun Dai, Linghui Pan
Article Number: 630
Published online on: 19 August 2022

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Circular RNA PVT1 promotes progression of thyroid cancer by competitively binding miR‑384

Tebo Hua, Yong Luo
Article Number: 629
Published online on: 19 August 2022

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Case Report Open Access

Adult‑onset X‑linked adrenal hypoplasia congenita caused by a novel mutation in DAX1/NR0B1: A case report and literature review

Yuhan Wang, Xiufen Liu, Xiaona Xie, Jingjing He, Ying Gao
Article Number: 628
Published online on: 19 August 2022

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Knockdown of the long non‑coding RNA CACNA1G‑AS1 enhances cytotoxicity and apoptosis of human diffuse large B cell lymphoma by regulating miR‑3160‑5p

Qiqi Zhou, Yan Zhang, Meiqing Zhao, Xia Zhao, Hongwei Xue, Shuxin Xiao
Article Number: 627
Published online on: 18 August 2022

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Article

Comparison of percutaneous and cutdown access‑related minor complications after endovascular aortic repair

Artur Rebelo, Patrick Voss, Ulrich Ronellenfitsch, Carsten Sekulla, Jörg Ukkat
Article Number: 626
Published online on: 17 August 2022

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Neoadjuvant apatinib plus tegafur/gimeracil/oteracil potassium (S‑1)/oxaliplatin chemotherapy vs. chemotherapy alone in patients with locally advanced gastric carcinoma

Zhenfeng Wang, Tingbang He, Deguo Yu, Xiantao Qin, Aizhi Geng, Hailei Yang
Article Number: 625
Published online on: 17 August 2022

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Case Report Open Access

Magnetic resonance imaging of a pediatric case of arthritis associated with acute lymphoblastic leukemia: A case report

Yuji Fujita, Shigeko Kuwashima, Tamae Kato, Megumi Sato, Makoto Ishikawa, Yuya Sato, Shigemi Yoshihara
Article Number: 624
Published online on: 16 August 2022

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Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis

Ziqian Liu, Cuijuan Zhang, Juan Hao, Gege Chen, Lingjin Liu, Yunzhao Xiong, Yi Chang, Hui Li, Tatsuo Shimosawa, Fan Yang, Qingyou Xu
Article Number: 623
Published online on: 11 August 2022

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LncRNA Meg3 promotes oxygen and glucose deprivation injury by decreasing angiogenesis in hBMECs by targeting the miR‑122‑5p/NDRG3 axis

Zhaoliang Luo, Tingliang Gong, Weihong Li, Wenqiang Tao
Article Number: 622
Published online on: 11 August 2022

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Cocktail therapy with prednisolone, vincristine and sirolimus for Kasabach‑Merritt phenomenon in 10 infants

Qianlong Liu, Na Xiong, Xinyuan Gong, Haochongyang Tong, Xuanfeng Tan, Xinkui Guo
Article Number: 621
Published online on: 09 August 2022

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Retraction Open Access

[Retracted] MicroRNA‑19a‑3p inhibits the cellular proliferation and invasion of non‑small cell lung cancer by downregulating UBAP2L

Yuejiang Pan, Ke Jin, Xuan Xie, Kexi Wang, Huizhong Zhang
Article Number: 620
Published online on: 09 August 2022

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Article Open Access

Application of alkaline phosphatase‑to‑platelet ratio as a novel noninvasive index predicts liver fibrosis in patients with chronic hepatitis B

Ying Pan, Kai Yang, Beibei Sun, Jin Chen, Pingping Tian
Article Number: 619
Published online on: 09 August 2022

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Article Open Access

Development of an animal model for rosacea‑like skin lesions caused by Demodex

Xue Luo, Nan Zhou, Lanxi Wu, Zhujun Wang, Jianhong Zhang, Xiuli Luan, Yang Luo
Article Number: 618
Published online on: 08 August 2022

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Case Report Open Access

Occurrence of hyperprogressive disease following administration of immune checkpoint inhibitors in lung squamous cell carcinoma: A case report

Shixia Dong, Kunjing Liu, Ruijuan Liu, Jing Zhuang
Article Number: 617
Published online on: 08 August 2022

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Article Open Access

Diagnostic and prognostic significance of SLC50A1 expression in patients with primary early breast cancer

Qunchen Zhang, Yutong Fang, Chuanghong She, Rongji Zheng, Chaoqun Hong, Chunfa Chen, Jundong Wu
Article Number: 616
Published online on: 05 August 2022

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Article Open Access

miR‑146a‑5p negatively regulates the IL‑1β‑stimulated inflammatory response via downregulation of the IRAK1/TRAF6 signaling pathway in human intestinal epithelial cells

Yanli Li, Shilian Tan, Yuanying Shen, Le Guo
Article Number: 615
Published online on: 05 August 2022

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Article Open Access

TMEM14A aggravates the progression of human ovarian cancer cells by enhancing the activity of glycolysis

Qingmei Zhang, Xiaohong Wang, Xuan Zhang, Jingfen Zhan, Binbin Zhang, Jin Jia, Jie Chen
Article Number: 614
Published online on: 05 August 2022

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TIPE2 protects cardiomyocytes from ischemia‑reperfusion‑induced apoptosis by decreasing cell autophagy via the mTORC1 signaling pathway

Gong Cheng, Xiaoyan Huang, Penghua You, Panpan Feng, Shuo Jia, Ji Zhang, Hongjun You, Fengjun Chang
Article Number: 613
Published online on: 04 August 2022

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Case Report Open Access

Transplantation of splenic tissue after splenectomy: A case report

Xiaoming Ma, Jiawei Gao, Yecheng Li, Jiaming Xie, Zhenyu Feng, Xin Jia, Wei Chen
Article Number: 612
Published online on: 03 August 2022

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Article Open Access

Influence of type II diabetes mellitus on postoperative complications following colorectal cancer surgery

Răzvan Cătălin Popescu, Nicoleta Leopa, Eugen Dumitru, Anca Florentina Mitroi, Cristina Tocia, Andrei Dumitru, Costel Brînzan, Florin Botea
Article Number: 611
Published online on: 02 August 2022

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Case Report Open Access

Masquelet technique combined with modified Sauve‑Kapandji, negative pressure drainage and flap transplantation for the treatment of a Gustilo‑Anderson III type C open fracture of the forearm: A case report

Yongjun Du, Chen Yu, Zhi Peng, Yan Lv, Wufei Ta, Sheng Lu
Article Number: 610
Published online on: 02 August 2022

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Review Open Access

Post‑COVID‑19 syndrome in children (Review)

Filippos Filippatos, Elizabeth-Barbara Tatsi, Athanasios Michos
Article Number: 609
Published online on: 02 August 2022

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Article Open Access

Riboflavin ameliorates mitochondrial dysfunction via the AMPK/PGC1α/HO‑1 signaling pathway and attenuates carbon tetrachloride‑induced liver fibrosis in rats

Ning Tang, Feng Hong, Wei Hao, Ting-Ting Yu, Guo-Guang Wang, Wei Li
Article Number: 608
Published online on: 02 August 2022

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Knockdown of triggering receptor expressed on myeloid cells 1 (TREM1) inhibits endoplasmic reticulum stress and reduces extracellular matrix degradation and the apoptosis of human nucleus pulposus cells

Ji Zhang, Haoran Jiang, Min Li, Lixiang Ding
Article Number: 607
Published online on: 29 July 2022

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Article

Clinical value of the sTim‑3 level in chronic kidney disease

Lingli Chen, Yuan Qin, Bo Lin, Xiaomei Yu, Shaoxiong Zheng, Xiumei Zhou, Xiaobin Liu, Yigang Wang, Biao Huang, Juan Jin, Liang Wang
Article Number: 606
Published online on: 29 July 2022

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Article Open Access

RRM2 regulates osteogenesis of mouse embryo fibroblasts via the Wnt/β‑catenin signaling pathway

Haijun Cai, Hui Guo, Yixuan Deng, Jinhai Jiang, Siyuan Liu, Wenge He, Huagang Jian
Article Number: 605
Published online on: 29 July 2022

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Journal Cover
January-2026 Volume 31 Issue 1

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Impact Factor: 2.3

Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Article Open Access

Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Article Open Access

Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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February-2026 Volume 31 Issue 2

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Published online on: 16 December 2025

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Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta‑analyses

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[Retracted] MicroRNA‑216b‑3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T‑LAK‑cell‑originated protein kinase

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Article Number: 50
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[Retracted] MicroRNA‑519a inhibits the proliferation and promotes the apoptosis of ovarian cancer cells through targeting signal transducer and activator of transcription 3

Fei Tian, Ligang Jia, Zhaoping Chu, Hua Han, Yuan Zhang, Jianhui Cai
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Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

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Article Number: 39
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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

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Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

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Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

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Published online on: 24 November 2025

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