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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2022 Volume 24 Issue 4

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Impact Factor: 2.3

Article

A retrospective study on the relationship between fibrosis‑4 index and all‑cause mortality in patients with acute myocardial infarction

Maolin Cao, Tingming Li, Zhifeng Li, Fang Gong, Zijun Chen
Article Number: 643
Published online on: 31 August 2022

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Increased TIGIT+PD‑1+CXCR5‑CD4+T cells are associated with disease activity in rheumatoid arthritis

Qing Luo, Peng Fu, Yongqin Guo, Biqi Fu, Yang Guo, Qingshui Huang, Zikun Huang, Junming Li
Article Number: 642
Published online on: 31 August 2022

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Case Report Open Access

A rare rectal gastrointestinal stromal tumor with indolent biological behavior: A case study

Jian Yang, Ying Liu, Xue-Jia Sun, Zhong-Wei Ai, Shi Liu
Article Number: 641
Published online on: 30 August 2022

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Review Open Access

Macrophages in melanoma: A double‑edged sword and targeted therapy strategies (Review)

Qiujun Zhou, Tingting Fang, Shenyu Wei, Shiqian Chai, Huifeng Yang, Maocan Tao, Yi Cao
Article Number: 640
Published online on: 26 August 2022

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1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways

Dong Wang, Yan Li, Liheng Dai, Yanxia Wang, Congna Zhao, Wangang Wang, Yu Zhang, Yinrui Zhao, Tingting Yu
Article Number: 639
Published online on: 26 August 2022

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HuR affects chemoresistance of small cell lung cancer by regulating FGFRL1 expression

Xun-Huang Duan, Rui Chen, Dao-Sheng Li, Ai-Hua Luo, Lin-Lang Guo
Article Number: 638
Published online on: 24 August 2022

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Article Open Access

Reverse shoulder arthroplasty vs. hemiarthroplasty for the treatment of osteoporotic proximal humeral fractures in elderly patients: A systematic review and meta‑analysis update

Peng-Fei Han, Su Yang, Yue-Peng Wang, Xue-Dong Hou, Yuan Li, Xi-Yong Li
Article Number: 637
Published online on: 24 August 2022

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Metformin suppresses foam cell formation, inflammation and ferroptosis via the AMPK/ERK signaling pathway in ox‑LDL‑induced THP‑1 monocytes

Yihan Zhao, Yizhen Zhao, Yuan Tian, Yang Zhou
Article Number: 636
Published online on: 24 August 2022

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Article Open Access

Effects of Brain Factor‑7® against motor deficit and oxidative stress in a mouse model of MPTP‑induced Parkinson's disease

Tae-Kyeong Lee, Jae-Chul Lee, Dae Won Kim, Ji-Won Lee, Sung-Su Kim, Hyung-Il Kim, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won, Soo Young Choi
Article Number: 635
Published online on: 24 August 2022

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mRNA and lncRNA expression profiles of liver tissues in children with biliary atresia

Wenyan Wu, Weifang Wu, Yongqin Ye, Tao Li, Bin Wang
Article Number: 634
Published online on: 22 August 2022

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Therapeutic effect of autologous bone marrow cells injected into the liver under the guidance of B‑ultrasound in the treatment of HBV‑related decompensated liver cirrhosis

Lei Li, Yanhui Si, Mingrong Cheng, Lin Lang, Aijun Li, Baochi Liu
Article Number: 633
Published online on: 22 August 2022

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Citrulline protects against LPS‑induced acute lung injury by inhibiting ROS/NLRP3‑dependent pyroptosis and apoptosis via the Nrf2 signaling pathway

Yao Xue, Yunqian Zhang, Li Chen, Yan Wang, Zhou Lv, Li-Qiao Yang, Siyuan Li
Article Number: 632
Published online on: 22 August 2022

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Case Report Open Access

Mediastinal cavernous angioleiomyoma: A case report and review of literature

Zhibo Zuo, Wanxin Wu, Xin Li, Lin Zhang, Jingyu Wang, Zhiqin Guo, Shaoqing Hu, Qi Zhang
Article Number: 631
Published online on: 22 August 2022

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Article Open Access

Propofol produces neurotoxicity by inducing mitochondrial apoptosis

Yubing Liang, Yu Huang, Rongge Shao, Fei Xiao, Fei Lin, Huijun Dai, Linghui Pan
Article Number: 630
Published online on: 19 August 2022

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Circular RNA PVT1 promotes progression of thyroid cancer by competitively binding miR‑384

Tebo Hua, Yong Luo
Article Number: 629
Published online on: 19 August 2022

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Case Report Open Access

Adult‑onset X‑linked adrenal hypoplasia congenita caused by a novel mutation in DAX1/NR0B1: A case report and literature review

Yuhan Wang, Xiufen Liu, Xiaona Xie, Jingjing He, Ying Gao
Article Number: 628
Published online on: 19 August 2022

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Knockdown of the long non‑coding RNA CACNA1G‑AS1 enhances cytotoxicity and apoptosis of human diffuse large B cell lymphoma by regulating miR‑3160‑5p

Qiqi Zhou, Yan Zhang, Meiqing Zhao, Xia Zhao, Hongwei Xue, Shuxin Xiao
Article Number: 627
Published online on: 18 August 2022

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Article

Comparison of percutaneous and cutdown access‑related minor complications after endovascular aortic repair

Artur Rebelo, Patrick Voss, Ulrich Ronellenfitsch, Carsten Sekulla, Jörg Ukkat
Article Number: 626
Published online on: 17 August 2022

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Article Open Access

Neoadjuvant apatinib plus tegafur/gimeracil/oteracil potassium (S‑1)/oxaliplatin chemotherapy vs. chemotherapy alone in patients with locally advanced gastric carcinoma

Zhenfeng Wang, Tingbang He, Deguo Yu, Xiantao Qin, Aizhi Geng, Hailei Yang
Article Number: 625
Published online on: 17 August 2022

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Case Report Open Access

Magnetic resonance imaging of a pediatric case of arthritis associated with acute lymphoblastic leukemia: A case report

Yuji Fujita, Shigeko Kuwashima, Tamae Kato, Megumi Sato, Makoto Ishikawa, Yuya Sato, Shigemi Yoshihara
Article Number: 624
Published online on: 16 August 2022

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Eplerenone ameliorates lung fibrosis in unilateral ureteral obstruction rats by inhibiting lymphangiogenesis

Ziqian Liu, Cuijuan Zhang, Juan Hao, Gege Chen, Lingjin Liu, Yunzhao Xiong, Yi Chang, Hui Li, Tatsuo Shimosawa, Fan Yang, Qingyou Xu
Article Number: 623
Published online on: 11 August 2022

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LncRNA Meg3 promotes oxygen and glucose deprivation injury by decreasing angiogenesis in hBMECs by targeting the miR‑122‑5p/NDRG3 axis

Zhaoliang Luo, Tingliang Gong, Weihong Li, Wenqiang Tao
Article Number: 622
Published online on: 11 August 2022

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Cocktail therapy with prednisolone, vincristine and sirolimus for Kasabach‑Merritt phenomenon in 10 infants

Qianlong Liu, Na Xiong, Xinyuan Gong, Haochongyang Tong, Xuanfeng Tan, Xinkui Guo
Article Number: 621
Published online on: 09 August 2022

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Retraction Open Access

[Retracted] MicroRNA‑19a‑3p inhibits the cellular proliferation and invasion of non‑small cell lung cancer by downregulating UBAP2L

Yuejiang Pan, Ke Jin, Xuan Xie, Kexi Wang, Huizhong Zhang
Article Number: 620
Published online on: 09 August 2022

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Article Open Access

Application of alkaline phosphatase‑to‑platelet ratio as a novel noninvasive index predicts liver fibrosis in patients with chronic hepatitis B

Ying Pan, Kai Yang, Beibei Sun, Jin Chen, Pingping Tian
Article Number: 619
Published online on: 09 August 2022

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Article Open Access

Development of an animal model for rosacea‑like skin lesions caused by Demodex

Xue Luo, Nan Zhou, Lanxi Wu, Zhujun Wang, Jianhong Zhang, Xiuli Luan, Yang Luo
Article Number: 618
Published online on: 08 August 2022

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Case Report Open Access

Occurrence of hyperprogressive disease following administration of immune checkpoint inhibitors in lung squamous cell carcinoma: A case report

Shixia Dong, Kunjing Liu, Ruijuan Liu, Jing Zhuang
Article Number: 617
Published online on: 08 August 2022

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Article Open Access

Diagnostic and prognostic significance of SLC50A1 expression in patients with primary early breast cancer

Qunchen Zhang, Yutong Fang, Chuanghong She, Rongji Zheng, Chaoqun Hong, Chunfa Chen, Jundong Wu
Article Number: 616
Published online on: 05 August 2022

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Article Open Access

miR‑146a‑5p negatively regulates the IL‑1β‑stimulated inflammatory response via downregulation of the IRAK1/TRAF6 signaling pathway in human intestinal epithelial cells

Yanli Li, Shilian Tan, Yuanying Shen, Le Guo
Article Number: 615
Published online on: 05 August 2022

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Article Open Access

TMEM14A aggravates the progression of human ovarian cancer cells by enhancing the activity of glycolysis

Qingmei Zhang, Xiaohong Wang, Xuan Zhang, Jingfen Zhan, Binbin Zhang, Jin Jia, Jie Chen
Article Number: 614
Published online on: 05 August 2022

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TIPE2 protects cardiomyocytes from ischemia‑reperfusion‑induced apoptosis by decreasing cell autophagy via the mTORC1 signaling pathway

Gong Cheng, Xiaoyan Huang, Penghua You, Panpan Feng, Shuo Jia, Ji Zhang, Hongjun You, Fengjun Chang
Article Number: 613
Published online on: 04 August 2022

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Case Report Open Access

Transplantation of splenic tissue after splenectomy: A case report

Xiaoming Ma, Jiawei Gao, Yecheng Li, Jiaming Xie, Zhenyu Feng, Xin Jia, Wei Chen
Article Number: 612
Published online on: 03 August 2022

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Article Open Access

Influence of type II diabetes mellitus on postoperative complications following colorectal cancer surgery

Răzvan Cătălin Popescu, Nicoleta Leopa, Eugen Dumitru, Anca Florentina Mitroi, Cristina Tocia, Andrei Dumitru, Costel Brînzan, Florin Botea
Article Number: 611
Published online on: 02 August 2022

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Case Report Open Access

Masquelet technique combined with modified Sauve‑Kapandji, negative pressure drainage and flap transplantation for the treatment of a Gustilo‑Anderson III type C open fracture of the forearm: A case report

Yongjun Du, Chen Yu, Zhi Peng, Yan Lv, Wufei Ta, Sheng Lu
Article Number: 610
Published online on: 02 August 2022

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Review Open Access

Post‑COVID‑19 syndrome in children (Review)

Filippos Filippatos, Elizabeth-Barbara Tatsi, Athanasios Michos
Article Number: 609
Published online on: 02 August 2022

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Article Open Access

Riboflavin ameliorates mitochondrial dysfunction via the AMPK/PGC1α/HO‑1 signaling pathway and attenuates carbon tetrachloride‑induced liver fibrosis in rats

Ning Tang, Feng Hong, Wei Hao, Ting-Ting Yu, Guo-Guang Wang, Wei Li
Article Number: 608
Published online on: 02 August 2022

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Knockdown of triggering receptor expressed on myeloid cells 1 (TREM1) inhibits endoplasmic reticulum stress and reduces extracellular matrix degradation and the apoptosis of human nucleus pulposus cells

Ji Zhang, Haoran Jiang, Min Li, Lixiang Ding
Article Number: 607
Published online on: 29 July 2022

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Article

Clinical value of the sTim‑3 level in chronic kidney disease

Lingli Chen, Yuan Qin, Bo Lin, Xiaomei Yu, Shaoxiong Zheng, Xiumei Zhou, Xiaobin Liu, Yigang Wang, Biao Huang, Juan Jin, Liang Wang
Article Number: 606
Published online on: 29 July 2022

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Article Open Access

RRM2 regulates osteogenesis of mouse embryo fibroblasts via the Wnt/β‑catenin signaling pathway

Haijun Cai, Hui Guo, Yixuan Deng, Jinhai Jiang, Siyuan Liu, Wenge He, Huagang Jian
Article Number: 605
Published online on: 29 July 2022

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Review Open Access

Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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