Journal Articles

Open Access

Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/γCnull (NOG) mice

Tsuyoshi Chijiwa, Yoshiyuki Abe, Norihiro Ikoma, Hitoshi Yamazaki, Hideo Tsukamoto, Hiroshi Suemizu, Kenji Kawai, Masatoshi Wakui, Chiyoko Nishime, Hozumi Matsumoto, Masahiro Matsuyama, Masaya Mukai, Yoshito Ueyama, Masato Nakamura

Pages: 5-13 Published online on: 01 January 2009

The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion

Ralf Hildenbrand, Antonela Schaaf

Pages: 15-23 Published online on: 01 January 2009

Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation

Dipa Patel, Rajiv Bassi, Andrea Hooper, Marie Prewett, Daniel J. Hicklin, Xiaoqiang Kang

Pages: 25-32 Published online on: 01 January 2009

GTI-2040 displays cooperative anti-tumor activity when combined with interferon α against human renal carcinoma xenografts

Aikaterini Vassilakos, Yoon Lee, Stéphane Viau, Ningping Feng, Hongnan Jin, Viengthong Chai, Ming Wang, Tina Avolio, Jim Wright, Aiping Young

Pages: 33-42 Published online on: 01 January 2009

Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2

Javier A. Menendez, Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Rocio Garcia-Villalba, Alegria Carrasco-Pancorbo, Alberto Fernandez-Gutierrez, Antonio Segura-Carretero

Pages: 43-51 Published online on: 01 January 2009

Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: implications for its role in tumor progression

Akihiro Toyoda, Hidetada Kawana, Kouji Azuhata, Jianyong Yu, Aya Omata, Hirohisa Kishi, Morihiro Higashi, Kenichi Harigaya

Pages: 53-60 Published online on: 01 January 2009

Multiple organ failure of tumor-bearing rabbits in cancer cachexia is caused by apoptosis of normal organ cells

Takeshi Fukuda, Toshiyuki Sumi, Hiroyuki Nobeyama, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Ken-Ichi Honda, Osamu Ishiko

Pages: 61-67 Published online on: 01 January 2009

p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB

C. Bottini, F. Platini, M. Rinaldi, M. Leutner, O. Alabiso, M. Garavoglia, L. Tessitore

Pages: 69-77 Published online on: 01 January 2009

Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade

Jianzhong Huang, Jae-O Bae, Judy P. Tsai, Angela Kadenhe-Chiweshe, Joey Papa, Alice Lee, Shan Zeng, Z. Noah Kornfeld, Paivi Ullner, Nibal Zaghloul, Ella Ioffe, Sarah Nandor, Elena Burova, Jocelyn Holash, Gavin Thurston, John Rudge, George D. Yancopoulos, Darrell J. Yamashiro, Jessica J. Kandel

Pages: 79-87 Published online on: 01 January 2009

Downregulation of the c-Fes protein-tyrosine kinase inhibits the proliferation of human renal carcinoma cells

Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake, Thomas E. Smithgall

Pages: 89-96 Published online on: 01 January 2009

An integrative genomic and proteomic approach to chemosensitivity prediction

Yan Ma, Zhenyu Ding, Yong Qian, Ying-Wooi Wan, Kursad Tosun, Xianglin Shi, Vincent Castranova, E. James Harner, Nancy L. Guo

Pages: 107-115 Published online on: 01 January 2009

Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma

Fen-Hwa Wong, Chi-Ying F. Huang, Li-Jen Su, Yu-Chung Wu, Yong-Shiang Lin, Jiun-Yi Hsia, Hsin-Ting Tsai, Sheng-An Lee, Chi-Hung Lin, Cheng-Hwai Tzeng, Po-Min Chen, Yann-Jan Chen, Shu-Ching Liang, Jin-Mei Lai, Chueh-Chuan Yen

Pages: 117-128 Published online on: 01 January 2009

Cyclin A1 regulates WT1 expression in acute myeloid leukemia cells

Utz Krug, Amber Yasmeen, Carmela Beger, Nicole Bäumer, Martin Dugas, Wolfgang E. Berdel, Carsten Müller-Tidow

Pages: 129-136 Published online on: 01 January 2009
Open Access

Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines

Dimitrios J. Stravopodis, Panagiotis K. Karkoulis, Eumorphia G. Konstantakou, Sophia Melachroinou, Antonis D. Lampidonis, Dimitra Anastasiou, Stefanos Kachrilas, Niki Messini-Nikolaki, Issidora S. Papassideri, Gerasimos Aravantinos, Lukas H. Margaritis, Gerassimos E. Voutsinas

Pages: 137-160 Published online on: 01 January 2009

Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches

Sojung Lee, Jungwoo Kang, Minchul Cho, Eunhee Seo, Heesook Choi, Eunjin Kim, Junghee Kim, Heejong Kim, Gum Yong Kang, Kwang Pyo Kim, Young-Ho Park, Dae-Yeul Yu, Young Na Yum, Sue-Nie Park, Do-Young Yoon

Pages: 161-172 Published online on: 01 January 2009

HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumour infiltrating cells after chemotherapy

Marie Indrová, Jana Bieblová, Joana Rossowska, Piotr Kuropka, Elzbieta Pajtasz-Piasecka, Jan Bubeník, Milan Reinis

Pages: 173-179 Published online on: 01 January 2009

The pattern of gene expression and possible relation of steroidogenic genes in oligodendroglial tumors

Ho Jun Seol, Jeong Eun Kim, Kyu-Chang Wang, Seung-Ki Kim, Jeong-Sun Seo, Sung-Hye Park, Hee-Won Jung

Pages: 181-190 Published online on: 01 January 2009

Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates

Sharad S. Singhal, Archana Sehrawat, Amee Mehta, Mukesh Sahu, Sanjay Awasthi

Pages: 191-199 Published online on: 01 January 2009

Anti-proliferative and apoptosis-inducible activity of Sarcodonin G from Sarcodon scabrosus in HeLa cells

Mei Dong, Shi-Ping Chen, Kazuko Kita, Yoshinobu Ichimura, Wen-Zhi Guo, Sa Lu, Shigeru Sugaya, Takaki Hiwasa, Masaki Takiguchi, Naomi Mori, Atsushi Kashima, Keiji Morimura, Mitsuru Hirota, Nobuo Suzuki

Pages: 201-207 Published online on: 01 January 2009

RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells

Venkateswara Rao Gogineni, Odysseas Kargiotis, Jeffrey D. Klopfenstein, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao

Pages: 209-218 Published online on: 01 January 2009

Combination of polymorphisms within 5' and 3' untranslated regions of thymidylate synthase gene modulates survival in 5 fluorouracil-treated colorectal cancer patients

María-Encarnación Fernández-Contreras, José Javier Sánchez-Hernández, Enrique González, Belén Herráez, Irene Domínguez, María Lozano, María-Luisa García De Paredes, Alberto Muñoz, Carlos Gamallo

Pages: 219-229 Published online on: 01 January 2009

Modification of gene expression induced by siRNA targeting of estrogen receptor α in MCF7 human breast cancer cells

Y. A. Luqmani, A. Al Azmi, M. Al Bader, G. Abraham, M. El Zawahri

Pages: 231-242 Published online on: 01 January 2009

α5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma

Susanne Sebens Müerköster, Jörn Kötteritzsch, Claudia Geismann, Daniela Gast, Marie-Luise Kruse, Peter Altevogt, Ulrich R. Fölsch, Heiner Schäfer

Pages: 243-253 Published online on: 01 January 2009

The platelet-derived growth factor receptor as a target for vascular endothelial growth factor-mediated anti-angiogenetic therapy in head and neck cancer

Birgit Bran, Gregor Bran, Karl Hörmann, Frank Riedel

Pages: 255-261 Published online on: 01 January 2009

Significance of multiple HPV infection in cervical cancer patients and its impact on treatment response

Radha Munagala, M. Gabriella Donà, Shesh N. Rai, Alferd B. Jenson, Nagarajan Bala, Shin J. Ghim, Ramesh C. Gupta

Pages: 263-271 Published online on: 01 January 2009

Immune-modulating and anti-vascular activities of two xanthenone acetic acid analogues: A comparative study to DMXAA

Mariagnese Barbera, Mikko I. Kettunen, Anna Caputo, De-En Hu, Silvia Gobbi, Kevin M. Brindle, Maria Carrara

Pages: 273-279 Published online on: 01 January 2009

Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death

Aruna Basu, Subrata Haldar

Pages: 281-286 Published online on: 01 January 2009

Sphingosine-1-phosphate inhibits the cytotoxic activity of NK cells via Gs protein-mediated signalling

Mariana Lagadari, Katja Lehmann, Mirjana Ziemer, Krisztina Truta-Feles, Luciana Berod, Marco Idzko, Dagmar Barz, Thomas Kamradt, Azzam A. Maghazachi, Johannes Norgauer

Pages: 287-294 Published online on: 01 January 2009
Journal Cover

Cover Legend PDF

January 2009
Volume 34 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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