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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2009 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/γCnull (NOG) mice

Tsuyoshi Chijiwa, Yoshiyuki Abe, Norihiro Ikoma, Hitoshi Yamazaki, Hideo Tsukamoto, Hiroshi Suemizu, Kenji Kawai, Masatoshi Wakui, Chiyoko Nishime, Hozumi Matsumoto, Masahiro Matsuyama, Masaya Mukai, Yoshito Ueyama, Masato Nakamura
Pages: 5-13
Published online on: 01 January 2009

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Article

The urokinase-system in tumor tissue stroma of the breast and breast cancer cell invasion

Ralf Hildenbrand, Antonela Schaaf
Pages: 15-23
Published online on: 01 January 2009

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Article

Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation

Dipa Patel, Rajiv Bassi, Andrea Hooper, Marie Prewett, Daniel J. Hicklin, Xiaoqiang Kang
Pages: 25-32
Published online on: 01 January 2009

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Article

GTI-2040 displays cooperative anti-tumor activity when combined with interferon α against human renal carcinoma xenografts

Aikaterini Vassilakos, Yoon Lee, Stéphane Viau, Ningping Feng, Hongnan Jin, Viengthong Chai, Ming Wang, Tina Avolio, Jim Wright, Aiping Young
Pages: 33-42
Published online on: 01 January 2009

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Article

Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2

Javier A. Menendez, Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Rocio Garcia-Villalba, Alegria Carrasco-Pancorbo, Alberto Fernandez-Gutierrez, Antonio Segura-Carretero
Pages: 43-51
Published online on: 01 January 2009

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Article

Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: implications for its role in tumor progression

Akihiro Toyoda, Hidetada Kawana, Kouji Azuhata, Jianyong Yu, Aya Omata, Hirohisa Kishi, Morihiro Higashi, Kenichi Harigaya
Pages: 53-60
Published online on: 01 January 2009

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Article

Multiple organ failure of tumor-bearing rabbits in cancer cachexia is caused by apoptosis of normal organ cells

Takeshi Fukuda, Toshiyuki Sumi, Hiroyuki Nobeyama, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Ken-Ichi Honda, Osamu Ishiko
Pages: 61-67
Published online on: 01 January 2009

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Article

p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB

C. Bottini, F. Platini, M. Rinaldi, M. Leutner, O. Alabiso, M. Garavoglia, L. Tessitore
Pages: 69-77
Published online on: 01 January 2009

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Article

Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade

Jianzhong Huang, Jae-O Bae, Judy P. Tsai, Angela Kadenhe-Chiweshe, Joey Papa, Alice Lee, Shan Zeng, Z. Noah Kornfeld, Paivi Ullner, Nibal Zaghloul, Ella Ioffe, Sarah Nandor, Elena Burova, Jocelyn Holash, Gavin Thurston, John Rudge, George D. Yancopoulos, Darrell J. Yamashiro, Jessica J. Kandel
Pages: 79-87
Published online on: 01 January 2009

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Article

Downregulation of the c-Fes protein-tyrosine kinase inhibits the proliferation of human renal carcinoma cells

Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake, Thomas E. Smithgall
Pages: 89-96
Published online on: 01 January 2009

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Article

SHIP2 phosphoinositol phosphatase positively regulates EGFR-Akt pathway, CXCR4 expression, and cell migration in MDA-MB-231 breast cancer cells

Nagendra K. Prasad
Pages: 97-105
Published online on: 01 January 2009

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Article

An integrative genomic and proteomic approach to chemosensitivity prediction

Yan Ma, Zhenyu Ding, Yong Qian, Ying-Wooi Wan, Kursad Tosun, Xianglin Shi, Vincent Castranova, E. James Harner, Nancy L. Guo
Pages: 107-115
Published online on: 01 January 2009

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Article

Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma

Fen-Hwa Wong, Chi-Ying F. Huang, Li-Jen Su, Yu-Chung Wu, Yong-Shiang Lin, Jiun-Yi Hsia, Hsin-Ting Tsai, Sheng-An Lee, Chi-Hung Lin, Cheng-Hwai Tzeng, Po-Min Chen, Yann-Jan Chen, Shu-Ching Liang, Jin-Mei Lai, Chueh-Chuan Yen
Pages: 117-128
Published online on: 01 January 2009

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Article

Cyclin A1 regulates WT1 expression in acute myeloid leukemia cells

Utz Krug, Amber Yasmeen, Carmela Beger, Nicole Bäumer, Martin Dugas, Wolfgang E. Berdel, Carsten Müller-Tidow
Pages: 129-136
Published online on: 01 January 2009

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Article Open Access

Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines

Dimitrios J. Stravopodis, Panagiotis K. Karkoulis, Eumorphia G. Konstantakou, Sophia Melachroinou, Antonis D. Lampidonis, Dimitra Anastasiou, Stefanos Kachrilas, Niki Messini-Nikolaki, Issidora S. Papassideri, Gerasimos Aravantinos, Lukas H. Margaritis, Gerassimos E. Voutsinas
Pages: 137-160
Published online on: 01 January 2009

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Article

Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches

Sojung Lee, Jungwoo Kang, Minchul Cho, Eunhee Seo, Heesook Choi, Eunjin Kim, Junghee Kim, Heejong Kim, Gum Yong Kang, Kwang Pyo Kim, Young-Ho Park, Dae-Yeul Yu, Young Na Yum, Sue-Nie Park, Do-Young Yoon
Pages: 161-172
Published online on: 01 January 2009

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Article

HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumour infiltrating cells after chemotherapy

Marie Indrová, Jana Bieblová, Joana Rossowska, Piotr Kuropka, Elzbieta Pajtasz-Piasecka, Jan Bubeník, Milan Reinis
Pages: 173-179
Published online on: 01 January 2009

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Article

The pattern of gene expression and possible relation of steroidogenic genes in oligodendroglial tumors

Ho Jun Seol, Jeong Eun Kim, Kyu-Chang Wang, Seung-Ki Kim, Jeong-Sun Seo, Sung-Hye Park, Hee-Won Jung
Pages: 181-190
Published online on: 01 January 2009

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Article

Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates

Sharad S. Singhal, Archana Sehrawat, Amee Mehta, Mukesh Sahu, Sanjay Awasthi
Pages: 191-199
Published online on: 01 January 2009

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Article

Anti-proliferative and apoptosis-inducible activity of Sarcodonin G from Sarcodon scabrosus in HeLa cells

Mei Dong, Shi-Ping Chen, Kazuko Kita, Yoshinobu Ichimura, Wen-Zhi Guo, Sa Lu, Shigeru Sugaya, Takaki Hiwasa, Masaki Takiguchi, Naomi Mori, Atsushi Kashima, Keiji Morimura, Mitsuru Hirota, Nobuo Suzuki
Pages: 201-207
Published online on: 01 January 2009

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Article

RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells

Venkateswara Rao Gogineni, Odysseas Kargiotis, Jeffrey D. Klopfenstein, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Pages: 209-218
Published online on: 01 January 2009

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Article

Combination of polymorphisms within 5' and 3' untranslated regions of thymidylate synthase gene modulates survival in 5 fluorouracil-treated colorectal cancer patients

María-Encarnación Fernández-Contreras, José Javier Sánchez-Hernández, Enrique González, Belén Herráez, Irene Domínguez, María Lozano, María-Luisa García De Paredes, Alberto Muñoz, Carlos Gamallo
Pages: 219-229
Published online on: 01 January 2009

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Article

Modification of gene expression induced by siRNA targeting of estrogen receptor α in MCF7 human breast cancer cells

Y. A. Luqmani, A. Al Azmi, M. Al Bader, G. Abraham, M. El Zawahri
Pages: 231-242
Published online on: 01 January 2009

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Article

α5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma

Susanne Sebens Müerköster, Jörn Kötteritzsch, Claudia Geismann, Daniela Gast, Marie-Luise Kruse, Peter Altevogt, Ulrich R. Fölsch, Heiner Schäfer
Pages: 243-253
Published online on: 01 January 2009

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Article

The platelet-derived growth factor receptor as a target for vascular endothelial growth factor-mediated anti-angiogenetic therapy in head and neck cancer

Birgit Bran, Gregor Bran, Karl Hörmann, Frank Riedel
Pages: 255-261
Published online on: 01 January 2009

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Article

Significance of multiple HPV infection in cervical cancer patients and its impact on treatment response

Radha Munagala, M. Gabriella Donà, Shesh N. Rai, Alferd B. Jenson, Nagarajan Bala, Shin J. Ghim, Ramesh C. Gupta
Pages: 263-271
Published online on: 01 January 2009

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Article

Immune-modulating and anti-vascular activities of two xanthenone acetic acid analogues: A comparative study to DMXAA

Mariagnese Barbera, Mikko I. Kettunen, Anna Caputo, De-En Hu, Silvia Gobbi, Kevin M. Brindle, Maria Carrara
Pages: 273-279
Published online on: 01 January 2009

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Article

Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death

Aruna Basu, Subrata Haldar
Pages: 281-286
Published online on: 01 January 2009

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Article

Sphingosine-1-phosphate inhibits the cytotoxic activity of NK cells via Gs protein-mediated signalling

Mariana Lagadari, Katja Lehmann, Mirjana Ziemer, Krisztina Truta-Feles, Luciana Berod, Marco Idzko, Dagmar Barz, Thomas Kamradt, Azzam A. Maghazachi, Johannes Norgauer
Pages: 287-294
Published online on: 01 January 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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