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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 11 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells

Marion Ganslmayer, Matthias Ocker, Steffen Zopf, Sandra Leitner, Eckhart G. Hahn, Detlef Schuppan, Christoph Herold
Pages: 943-950
Published online on: 01 May 2004

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Article

Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer

Kalisha A. Hill, Kim L. Wang, Steven J. Stryker, Rohit Gupta, David M. Weinrach, M. S. Rao
Pages: 951-956
Published online on: 01 May 2004

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Article

Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines

Jagan M.R. Patlolla, Malisetty V. Swamy, Jayadev Raju, Chinthalapally V. Rao
Pages: 957-963
Published online on: 01 May 2004

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Article

Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils

Yoshinori Tanaka, Harushi Osugi, Keiichirou Morimura, Masashi Takemura, Masakatsu Ueno, Masahiro Kaneko, Shoji Fukushima, Hiroaki Kinoshita
Pages: 965-971
Published online on: 01 May 2004

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Article

Establishment of enzyme-linked immunosorbent assays for thymidylate synthase and dihydropyriminide dehydrogenase in cancer tissues

Junichi Kurebayashi, Yutaka Yamamoto, Kiyoshi Udagawa, Sumiko Okubo, Masakazu Fukushima, Hiroshi Sonoo
Pages: 973-979
Published online on: 01 May 2004

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Article

Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats

Jun Takeda, Kazuaki Kitajima, Shigehiko Fujii, Hideki Horiuchi, Hiroshige Hori, Yoko Chibana, Takashi Okuyama, Keiichi Tominaga, Kazuhito Ichikawa, Yuko Ono, Tadahisa Teramoto, Yasuo Ohkura, Joji Imura, Motoo Shinoda, Tsutomu Chiba, Choitsu Sakamoto, Hitoshi Kawamata, Takahiro Fujimori
Pages: 981-985
Published online on: 01 May 2004

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Article

Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer

Gulnar Kurban, Toshiyuki Ishiwata, Mitsuhiro Kudo, Munehiro Yokoyama, Yuichi Sugisaki, Zenya Naito
Pages: 987-991
Published online on: 01 May 2004

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Article

Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation

Xiaodong Tan, Yasuhiro Tamori, Hiroshi Egami, Shinji Ishikawa, Takashi Kurizaki, Eiji Takai, Masahiko Hirota, Michio Ogawa
Pages: 993-998
Published online on: 01 May 2004

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Article

Detection of bone marrow micrometastasis in esophageal cancer patients by immunomagnetic separation

Tsutomu Nakamura, Katsuhiro Matsunami, Kazuhiko Hayashi, Masaho Ota, Hiroko Ide, Ken Takasaki
Pages: 999-1003
Published online on: 01 May 2004

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Article

Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder

Syed A. Hussain, Daniel H. Palmer, Raji Ganesan, Louise Hiller, John Gregory, Paul G. Murray, Jaromir Pastorek, Lawrence Young, Nicholas D. James
Pages: 1005-1010
Published online on: 01 May 2004

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Article

PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma

Tsuyoshi Saito, Yoshinao Oda, Ken-Ichi Kawaguchi, Tomonari Takahira, Hidetaka Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Akio Sakamoto, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 1011-1015
Published online on: 01 May 2004

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Article

Human dendritic cells mediate anti-tumor activity against hematopoietic tumor cells without direct contact and Fas/FasL killing pathway

Flávio Monteiro Ayres, Miwako Narita, Masuhiro Takahashi, Toshio Yano, Aichun Liu, Ken Toba, Tatsuo Furukawa, Yoshifusa Aizawa
Pages: 1017-1023
Published online on: 01 May 2004

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Article

Growth inhibition and induction of apoptosis by flavopiridol in rat lung adenocarcinoma, osteosarcoma and malignant fibrous histiocytoma cell lines

Kanya Honoki, Kazuhiro Yoshitani, Toshifumi Tsujiuchi, Toshio Mori, Masahiro Tsutsumi, Toru Morishita, Yoshinori Takakura, Yoshio Mii
Pages: 1025-1030
Published online on: 01 May 2004

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Article

Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 1031-1039
Published online on: 01 May 2004

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Article

Genome-wide cDNA microarray screening to correlate gene expression profile with survival in patients with advanced lung cancer

Mizuki Ikehara, Fumihiro Oshita, Akiko Sekiyama, Nobuyuki Hamanaka, Haruhiro Saito, Kouzo Yamada, Kazumasa Noda, Yoichi Kameda, Yohei Miyagi
Pages: 1041-1044
Published online on: 01 May 2004

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Article

Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 1045-1051
Published online on: 01 May 2004

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Article

Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells

Takemi Otsuki, Haruko Sakaguchi, Tamayo Hatayama, Tomohiro Fujii, Takayuki Tsujioka, Takashi Sugihara, Akiko Takata, Fuminori Hyodoh, Masaaki Eto
Pages: 1053-1058
Published online on: 01 May 2004

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Article

Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells

Yasushi Takenouchi, Myat Lin Oo, Takeshi Senga, Yasuo Watanabe, Kazuya Machida, Kou Miyazaki, Yuji Nimura, Michinari Hamaguchi
Pages: 1059-1062
Published online on: 01 May 2004

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Article

The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer

Juichiro Konishi, Shinichi Toyooka, Motoi Aoe, Yasushi Omura, Kazuhiro Washio, Kazunori Tsukuda, Nobuyoshi Shimizu
Pages: 1063-1067
Published online on: 01 May 2004

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Article

Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides

Birgit Hagenauer, Alexandra Maier-Salamon, Theresia Thalhammer, Peter Zöllner, Adrian Senderowicz, Walter Jäger
Pages: 1069-1075
Published online on: 01 May 2004

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Article

High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: A prospective study

Ronnie Tung-Ping Poon, Cecilia Lau, Wan-Ching Yu, Sheung-Tat Fan, John Wong
Pages: 1077-1084
Published online on: 01 May 2004

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Article

Expression of splicing factors in human ovarian cancer

D.-C. Fischer, Kathleen Noack, Ingo B. Runnebaum, Dirk O. Watermann, Dirk G. Kieback, Stefan Stamm, Elmar Stickeler
Pages: 1085-1090
Published online on: 01 May 2004

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Article

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

Marina Pajic, Mary Bebawy, Janelle M. Hoskins, Basil D. Roufogalis, Laurent P. Rivory
Pages: 1091-1095
Published online on: 01 May 2004

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Article

Characterization of stem cell factor gene-modified human natural killer cell line, NK-92 cells: Implication in NK cell-based adoptive cellular immunotherapy

Jian Zhang, Rui Sun, Haiming Wei, Jianhua Zhang, Zhigang Tian
Pages: 1097-1106
Published online on: 01 May 2004

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Article

Chemoembolization of rat liver metastasis with microspheres and gemcitabine followed by evaluation of tumor cell load by chemiluminescence

Matthias H. Seelig, Meike Leible, Jan Sänger, Martin R. Berger
Pages: 1107-1113
Published online on: 01 May 2004

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Article

P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population

Hongbing Shen, Ana Solari, Xinru Wang, Zhengdong Zhang, Yaochu Xu, Liwei Wang, Xu Hu, Jiantao Guo, Qingyi Wei
Pages: 1115-1120
Published online on: 01 May 2004

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Article

Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Marta Alicja Lazarczyk, Lukasz Milewski, Piotr Dziunycz, Piotr Skopinski, Jakub Golab
Pages: 1121-1125
Published online on: 01 May 2004

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Article

Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro

Maciej Kopec, Katarzyna Strusinska, Magdalena Legat, Marcin Makowski, Marek Jakobisiak, Jakub Golab
Pages: 1127-1131
Published online on: 01 May 2004

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Article Open Access

Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Review Open Access

Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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Retraction Open Access

[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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Article Open Access

NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Article

Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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Retraction Open Access

[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Review Open Access

Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Article Open Access

Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Article Open Access

Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Article Open Access

Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review)

Hiba Al Sayegh, Zahraa Assi, Amjad Kanaan, Mirvat El Sibai
Article Number: 86
Published online on: 03 March 2026

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Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held‑Feindt
Article Number: 85
Published online on: 02 March 2026

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[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Article Open Access

Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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