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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 11 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells

Marion Ganslmayer, Matthias Ocker, Steffen Zopf, Sandra Leitner, Eckhart G. Hahn, Detlef Schuppan, Christoph Herold
Pages: 943-950
Published online on: 01 May 2004

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Article

Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer

Kalisha A. Hill, Kim L. Wang, Steven J. Stryker, Rohit Gupta, David M. Weinrach, M. S. Rao
Pages: 951-956
Published online on: 01 May 2004

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Article

Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines

Jagan M.R. Patlolla, Malisetty V. Swamy, Jayadev Raju, Chinthalapally V. Rao
Pages: 957-963
Published online on: 01 May 2004

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Article

Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils

Yoshinori Tanaka, Harushi Osugi, Keiichirou Morimura, Masashi Takemura, Masakatsu Ueno, Masahiro Kaneko, Shoji Fukushima, Hiroaki Kinoshita
Pages: 965-971
Published online on: 01 May 2004

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Article

Establishment of enzyme-linked immunosorbent assays for thymidylate synthase and dihydropyriminide dehydrogenase in cancer tissues

Junichi Kurebayashi, Yutaka Yamamoto, Kiyoshi Udagawa, Sumiko Okubo, Masakazu Fukushima, Hiroshi Sonoo
Pages: 973-979
Published online on: 01 May 2004

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Article

Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats

Jun Takeda, Kazuaki Kitajima, Shigehiko Fujii, Hideki Horiuchi, Hiroshige Hori, Yoko Chibana, Takashi Okuyama, Keiichi Tominaga, Kazuhito Ichikawa, Yuko Ono, Tadahisa Teramoto, Yasuo Ohkura, Joji Imura, Motoo Shinoda, Tsutomu Chiba, Choitsu Sakamoto, Hitoshi Kawamata, Takahiro Fujimori
Pages: 981-985
Published online on: 01 May 2004

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Article

Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer

Gulnar Kurban, Toshiyuki Ishiwata, Mitsuhiro Kudo, Munehiro Yokoyama, Yuichi Sugisaki, Zenya Naito
Pages: 987-991
Published online on: 01 May 2004

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Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation

Xiaodong Tan, Yasuhiro Tamori, Hiroshi Egami, Shinji Ishikawa, Takashi Kurizaki, Eiji Takai, Masahiko Hirota, Michio Ogawa
Pages: 993-998
Published online on: 01 May 2004

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Article

Detection of bone marrow micrometastasis in esophageal cancer patients by immunomagnetic separation

Tsutomu Nakamura, Katsuhiro Matsunami, Kazuhiko Hayashi, Masaho Ota, Hiroko Ide, Ken Takasaki
Pages: 999-1003
Published online on: 01 May 2004

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Article

Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder

Syed A. Hussain, Daniel H. Palmer, Raji Ganesan, Louise Hiller, John Gregory, Paul G. Murray, Jaromir Pastorek, Lawrence Young, Nicholas D. James
Pages: 1005-1010
Published online on: 01 May 2004

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Article

PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma

Tsuyoshi Saito, Yoshinao Oda, Ken-Ichi Kawaguchi, Tomonari Takahira, Hidetaka Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Akio Sakamoto, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 1011-1015
Published online on: 01 May 2004

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Article

Human dendritic cells mediate anti-tumor activity against hematopoietic tumor cells without direct contact and Fas/FasL killing pathway

Flávio Monteiro Ayres, Miwako Narita, Masuhiro Takahashi, Toshio Yano, Aichun Liu, Ken Toba, Tatsuo Furukawa, Yoshifusa Aizawa
Pages: 1017-1023
Published online on: 01 May 2004

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Article

Growth inhibition and induction of apoptosis by flavopiridol in rat lung adenocarcinoma, osteosarcoma and malignant fibrous histiocytoma cell lines

Kanya Honoki, Kazuhiro Yoshitani, Toshifumi Tsujiuchi, Toshio Mori, Masahiro Tsutsumi, Toru Morishita, Yoshinori Takakura, Yoshio Mii
Pages: 1025-1030
Published online on: 01 May 2004

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Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 1031-1039
Published online on: 01 May 2004

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Genome-wide cDNA microarray screening to correlate gene expression profile with survival in patients with advanced lung cancer

Mizuki Ikehara, Fumihiro Oshita, Akiko Sekiyama, Nobuyuki Hamanaka, Haruhiro Saito, Kouzo Yamada, Kazumasa Noda, Yoichi Kameda, Yohei Miyagi
Pages: 1041-1044
Published online on: 01 May 2004

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Article

Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 1045-1051
Published online on: 01 May 2004

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Article

Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells

Takemi Otsuki, Haruko Sakaguchi, Tamayo Hatayama, Tomohiro Fujii, Takayuki Tsujioka, Takashi Sugihara, Akiko Takata, Fuminori Hyodoh, Masaaki Eto
Pages: 1053-1058
Published online on: 01 May 2004

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Article

Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells

Yasushi Takenouchi, Myat Lin Oo, Takeshi Senga, Yasuo Watanabe, Kazuya Machida, Kou Miyazaki, Yuji Nimura, Michinari Hamaguchi
Pages: 1059-1062
Published online on: 01 May 2004

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Article

The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer

Juichiro Konishi, Shinichi Toyooka, Motoi Aoe, Yasushi Omura, Kazuhiro Washio, Kazunori Tsukuda, Nobuyoshi Shimizu
Pages: 1063-1067
Published online on: 01 May 2004

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Article

Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides

Birgit Hagenauer, Alexandra Maier-Salamon, Theresia Thalhammer, Peter Zöllner, Adrian Senderowicz, Walter Jäger
Pages: 1069-1075
Published online on: 01 May 2004

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Article

High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: A prospective study

Ronnie Tung-Ping Poon, Cecilia Lau, Wan-Ching Yu, Sheung-Tat Fan, John Wong
Pages: 1077-1084
Published online on: 01 May 2004

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Article

Expression of splicing factors in human ovarian cancer

D.-C. Fischer, Kathleen Noack, Ingo B. Runnebaum, Dirk O. Watermann, Dirk G. Kieback, Stefan Stamm, Elmar Stickeler
Pages: 1085-1090
Published online on: 01 May 2004

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Article

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

Marina Pajic, Mary Bebawy, Janelle M. Hoskins, Basil D. Roufogalis, Laurent P. Rivory
Pages: 1091-1095
Published online on: 01 May 2004

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Article

Characterization of stem cell factor gene-modified human natural killer cell line, NK-92 cells: Implication in NK cell-based adoptive cellular immunotherapy

Jian Zhang, Rui Sun, Haiming Wei, Jianhua Zhang, Zhigang Tian
Pages: 1097-1106
Published online on: 01 May 2004

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Article

Chemoembolization of rat liver metastasis with microspheres and gemcitabine followed by evaluation of tumor cell load by chemiluminescence

Matthias H. Seelig, Meike Leible, Jan Sänger, Martin R. Berger
Pages: 1107-1113
Published online on: 01 May 2004

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Article

P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population

Hongbing Shen, Ana Solari, Xinru Wang, Zhengdong Zhang, Yaochu Xu, Liwei Wang, Xu Hu, Jiantao Guo, Qingyi Wei
Pages: 1115-1120
Published online on: 01 May 2004

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Article

Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Marta Alicja Lazarczyk, Lukasz Milewski, Piotr Dziunycz, Piotr Skopinski, Jakub Golab
Pages: 1121-1125
Published online on: 01 May 2004

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Article

Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro

Maciej Kopec, Katarzyna Strusinska, Magdalena Legat, Marcin Makowski, Marek Jakobisiak, Jakub Golab
Pages: 1127-1131
Published online on: 01 May 2004

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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