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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 11 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells

Marion Ganslmayer, Matthias Ocker, Steffen Zopf, Sandra Leitner, Eckhart G. Hahn, Detlef Schuppan, Christoph Herold
Pages: 943-950
Published online on: 01 May 2004

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Article

Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer

Kalisha A. Hill, Kim L. Wang, Steven J. Stryker, Rohit Gupta, David M. Weinrach, M. S. Rao
Pages: 951-956
Published online on: 01 May 2004

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Article

Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines

Jagan M.R. Patlolla, Malisetty V. Swamy, Jayadev Raju, Chinthalapally V. Rao
Pages: 957-963
Published online on: 01 May 2004

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Article

Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils

Yoshinori Tanaka, Harushi Osugi, Keiichirou Morimura, Masashi Takemura, Masakatsu Ueno, Masahiro Kaneko, Shoji Fukushima, Hiroaki Kinoshita
Pages: 965-971
Published online on: 01 May 2004

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Article

Establishment of enzyme-linked immunosorbent assays for thymidylate synthase and dihydropyriminide dehydrogenase in cancer tissues

Junichi Kurebayashi, Yutaka Yamamoto, Kiyoshi Udagawa, Sumiko Okubo, Masakazu Fukushima, Hiroshi Sonoo
Pages: 973-979
Published online on: 01 May 2004

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Article

Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats

Jun Takeda, Kazuaki Kitajima, Shigehiko Fujii, Hideki Horiuchi, Hiroshige Hori, Yoko Chibana, Takashi Okuyama, Keiichi Tominaga, Kazuhito Ichikawa, Yuko Ono, Tadahisa Teramoto, Yasuo Ohkura, Joji Imura, Motoo Shinoda, Tsutomu Chiba, Choitsu Sakamoto, Hitoshi Kawamata, Takahiro Fujimori
Pages: 981-985
Published online on: 01 May 2004

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Article

Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer

Gulnar Kurban, Toshiyuki Ishiwata, Mitsuhiro Kudo, Munehiro Yokoyama, Yuichi Sugisaki, Zenya Naito
Pages: 987-991
Published online on: 01 May 2004

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Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation

Xiaodong Tan, Yasuhiro Tamori, Hiroshi Egami, Shinji Ishikawa, Takashi Kurizaki, Eiji Takai, Masahiko Hirota, Michio Ogawa
Pages: 993-998
Published online on: 01 May 2004

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Article

Detection of bone marrow micrometastasis in esophageal cancer patients by immunomagnetic separation

Tsutomu Nakamura, Katsuhiro Matsunami, Kazuhiko Hayashi, Masaho Ota, Hiroko Ide, Ken Takasaki
Pages: 999-1003
Published online on: 01 May 2004

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Article

Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder

Syed A. Hussain, Daniel H. Palmer, Raji Ganesan, Louise Hiller, John Gregory, Paul G. Murray, Jaromir Pastorek, Lawrence Young, Nicholas D. James
Pages: 1005-1010
Published online on: 01 May 2004

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Article

PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma

Tsuyoshi Saito, Yoshinao Oda, Ken-Ichi Kawaguchi, Tomonari Takahira, Hidetaka Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Akio Sakamoto, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 1011-1015
Published online on: 01 May 2004

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Article

Human dendritic cells mediate anti-tumor activity against hematopoietic tumor cells without direct contact and Fas/FasL killing pathway

Flávio Monteiro Ayres, Miwako Narita, Masuhiro Takahashi, Toshio Yano, Aichun Liu, Ken Toba, Tatsuo Furukawa, Yoshifusa Aizawa
Pages: 1017-1023
Published online on: 01 May 2004

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Article

Growth inhibition and induction of apoptosis by flavopiridol in rat lung adenocarcinoma, osteosarcoma and malignant fibrous histiocytoma cell lines

Kanya Honoki, Kazuhiro Yoshitani, Toshifumi Tsujiuchi, Toshio Mori, Masahiro Tsutsumi, Toru Morishita, Yoshinori Takakura, Yoshio Mii
Pages: 1025-1030
Published online on: 01 May 2004

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Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 1031-1039
Published online on: 01 May 2004

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Genome-wide cDNA microarray screening to correlate gene expression profile with survival in patients with advanced lung cancer

Mizuki Ikehara, Fumihiro Oshita, Akiko Sekiyama, Nobuyuki Hamanaka, Haruhiro Saito, Kouzo Yamada, Kazumasa Noda, Yoichi Kameda, Yohei Miyagi
Pages: 1041-1044
Published online on: 01 May 2004

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Article

Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 1045-1051
Published online on: 01 May 2004

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Article

Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells

Takemi Otsuki, Haruko Sakaguchi, Tamayo Hatayama, Tomohiro Fujii, Takayuki Tsujioka, Takashi Sugihara, Akiko Takata, Fuminori Hyodoh, Masaaki Eto
Pages: 1053-1058
Published online on: 01 May 2004

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Article

Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells

Yasushi Takenouchi, Myat Lin Oo, Takeshi Senga, Yasuo Watanabe, Kazuya Machida, Kou Miyazaki, Yuji Nimura, Michinari Hamaguchi
Pages: 1059-1062
Published online on: 01 May 2004

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The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer

Juichiro Konishi, Shinichi Toyooka, Motoi Aoe, Yasushi Omura, Kazuhiro Washio, Kazunori Tsukuda, Nobuyoshi Shimizu
Pages: 1063-1067
Published online on: 01 May 2004

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Article

Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides

Birgit Hagenauer, Alexandra Maier-Salamon, Theresia Thalhammer, Peter Zöllner, Adrian Senderowicz, Walter Jäger
Pages: 1069-1075
Published online on: 01 May 2004

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Article

High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: A prospective study

Ronnie Tung-Ping Poon, Cecilia Lau, Wan-Ching Yu, Sheung-Tat Fan, John Wong
Pages: 1077-1084
Published online on: 01 May 2004

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Article

Expression of splicing factors in human ovarian cancer

D.-C. Fischer, Kathleen Noack, Ingo B. Runnebaum, Dirk O. Watermann, Dirk G. Kieback, Stefan Stamm, Elmar Stickeler
Pages: 1085-1090
Published online on: 01 May 2004

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Article

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

Marina Pajic, Mary Bebawy, Janelle M. Hoskins, Basil D. Roufogalis, Laurent P. Rivory
Pages: 1091-1095
Published online on: 01 May 2004

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Article

Characterization of stem cell factor gene-modified human natural killer cell line, NK-92 cells: Implication in NK cell-based adoptive cellular immunotherapy

Jian Zhang, Rui Sun, Haiming Wei, Jianhua Zhang, Zhigang Tian
Pages: 1097-1106
Published online on: 01 May 2004

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Article

Chemoembolization of rat liver metastasis with microspheres and gemcitabine followed by evaluation of tumor cell load by chemiluminescence

Matthias H. Seelig, Meike Leible, Jan Sänger, Martin R. Berger
Pages: 1107-1113
Published online on: 01 May 2004

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Article

P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population

Hongbing Shen, Ana Solari, Xinru Wang, Zhengdong Zhang, Yaochu Xu, Liwei Wang, Xu Hu, Jiantao Guo, Qingyi Wei
Pages: 1115-1120
Published online on: 01 May 2004

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Article

Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Marta Alicja Lazarczyk, Lukasz Milewski, Piotr Dziunycz, Piotr Skopinski, Jakub Golab
Pages: 1121-1125
Published online on: 01 May 2004

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Article

Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro

Maciej Kopec, Katarzyna Strusinska, Magdalena Legat, Marcin Makowski, Marek Jakobisiak, Jakub Golab
Pages: 1127-1131
Published online on: 01 May 2004

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.m. Tong, Anthony W.h. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.c. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani‑Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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