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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 11 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells

Marion Ganslmayer, Matthias Ocker, Steffen Zopf, Sandra Leitner, Eckhart G. Hahn, Detlef Schuppan, Christoph Herold
Pages: 943-950
Published online on: 01 May 2004

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Article

Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer

Kalisha A. Hill, Kim L. Wang, Steven J. Stryker, Rohit Gupta, David M. Weinrach, M. S. Rao
Pages: 951-956
Published online on: 01 May 2004

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Article

Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines

Jagan M.R. Patlolla, Malisetty V. Swamy, Jayadev Raju, Chinthalapally V. Rao
Pages: 957-963
Published online on: 01 May 2004

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Article

Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils

Yoshinori Tanaka, Harushi Osugi, Keiichirou Morimura, Masashi Takemura, Masakatsu Ueno, Masahiro Kaneko, Shoji Fukushima, Hiroaki Kinoshita
Pages: 965-971
Published online on: 01 May 2004

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Article

Establishment of enzyme-linked immunosorbent assays for thymidylate synthase and dihydropyriminide dehydrogenase in cancer tissues

Junichi Kurebayashi, Yutaka Yamamoto, Kiyoshi Udagawa, Sumiko Okubo, Masakazu Fukushima, Hiroshi Sonoo
Pages: 973-979
Published online on: 01 May 2004

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Article

Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats

Jun Takeda, Kazuaki Kitajima, Shigehiko Fujii, Hideki Horiuchi, Hiroshige Hori, Yoko Chibana, Takashi Okuyama, Keiichi Tominaga, Kazuhito Ichikawa, Yuko Ono, Tadahisa Teramoto, Yasuo Ohkura, Joji Imura, Motoo Shinoda, Tsutomu Chiba, Choitsu Sakamoto, Hitoshi Kawamata, Takahiro Fujimori
Pages: 981-985
Published online on: 01 May 2004

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Article

Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in human uterine cervical cancer

Gulnar Kurban, Toshiyuki Ishiwata, Mitsuhiro Kudo, Munehiro Yokoyama, Yuichi Sugisaki, Zenya Naito
Pages: 987-991
Published online on: 01 May 2004

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Article

Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation

Xiaodong Tan, Yasuhiro Tamori, Hiroshi Egami, Shinji Ishikawa, Takashi Kurizaki, Eiji Takai, Masahiko Hirota, Michio Ogawa
Pages: 993-998
Published online on: 01 May 2004

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Article

Detection of bone marrow micrometastasis in esophageal cancer patients by immunomagnetic separation

Tsutomu Nakamura, Katsuhiro Matsunami, Kazuhiko Hayashi, Masaho Ota, Hiroko Ide, Ken Takasaki
Pages: 999-1003
Published online on: 01 May 2004

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Article

Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder

Syed A. Hussain, Daniel H. Palmer, Raji Ganesan, Louise Hiller, John Gregory, Paul G. Murray, Jaromir Pastorek, Lawrence Young, Nicholas D. James
Pages: 1005-1010
Published online on: 01 May 2004

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Article

PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma

Tsuyoshi Saito, Yoshinao Oda, Ken-Ichi Kawaguchi, Tomonari Takahira, Hidetaka Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Akio Sakamoto, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 1011-1015
Published online on: 01 May 2004

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Article

Human dendritic cells mediate anti-tumor activity against hematopoietic tumor cells without direct contact and Fas/FasL killing pathway

Flávio Monteiro Ayres, Miwako Narita, Masuhiro Takahashi, Toshio Yano, Aichun Liu, Ken Toba, Tatsuo Furukawa, Yoshifusa Aizawa
Pages: 1017-1023
Published online on: 01 May 2004

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Article

Growth inhibition and induction of apoptosis by flavopiridol in rat lung adenocarcinoma, osteosarcoma and malignant fibrous histiocytoma cell lines

Kanya Honoki, Kazuhiro Yoshitani, Toshifumi Tsujiuchi, Toshio Mori, Masahiro Tsutsumi, Toru Morishita, Yoshinori Takakura, Yoshio Mii
Pages: 1025-1030
Published online on: 01 May 2004

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Article

Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 1031-1039
Published online on: 01 May 2004

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Article

Genome-wide cDNA microarray screening to correlate gene expression profile with survival in patients with advanced lung cancer

Mizuki Ikehara, Fumihiro Oshita, Akiko Sekiyama, Nobuyuki Hamanaka, Haruhiro Saito, Kouzo Yamada, Kazumasa Noda, Yoichi Kameda, Yohei Miyagi
Pages: 1041-1044
Published online on: 01 May 2004

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Article

Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers

Tsukasa Hotta, Katsutoshi Taniguchi, Yasuhito Kobayashi, Kiyofumi Johata, Masaki Sahara, Teiji Naka, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 1045-1051
Published online on: 01 May 2004

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Article

Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells

Takemi Otsuki, Haruko Sakaguchi, Tamayo Hatayama, Tomohiro Fujii, Takayuki Tsujioka, Takashi Sugihara, Akiko Takata, Fuminori Hyodoh, Masaaki Eto
Pages: 1053-1058
Published online on: 01 May 2004

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Article

Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells

Yasushi Takenouchi, Myat Lin Oo, Takeshi Senga, Yasuo Watanabe, Kazuya Machida, Kou Miyazaki, Yuji Nimura, Michinari Hamaguchi
Pages: 1059-1062
Published online on: 01 May 2004

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Article

The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer

Juichiro Konishi, Shinichi Toyooka, Motoi Aoe, Yasushi Omura, Kazuhiro Washio, Kazunori Tsukuda, Nobuyoshi Shimizu
Pages: 1063-1067
Published online on: 01 May 2004

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Article

Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides

Birgit Hagenauer, Alexandra Maier-Salamon, Theresia Thalhammer, Peter Zöllner, Adrian Senderowicz, Walter Jäger
Pages: 1069-1075
Published online on: 01 May 2004

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Article

High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: A prospective study

Ronnie Tung-Ping Poon, Cecilia Lau, Wan-Ching Yu, Sheung-Tat Fan, John Wong
Pages: 1077-1084
Published online on: 01 May 2004

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Article

Expression of splicing factors in human ovarian cancer

D.-C. Fischer, Kathleen Noack, Ingo B. Runnebaum, Dirk O. Watermann, Dirk G. Kieback, Stefan Stamm, Elmar Stickeler
Pages: 1085-1090
Published online on: 01 May 2004

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Article

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

Marina Pajic, Mary Bebawy, Janelle M. Hoskins, Basil D. Roufogalis, Laurent P. Rivory
Pages: 1091-1095
Published online on: 01 May 2004

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Article

Characterization of stem cell factor gene-modified human natural killer cell line, NK-92 cells: Implication in NK cell-based adoptive cellular immunotherapy

Jian Zhang, Rui Sun, Haiming Wei, Jianhua Zhang, Zhigang Tian
Pages: 1097-1106
Published online on: 01 May 2004

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Article

Chemoembolization of rat liver metastasis with microspheres and gemcitabine followed by evaluation of tumor cell load by chemiluminescence

Matthias H. Seelig, Meike Leible, Jan Sänger, Martin R. Berger
Pages: 1107-1113
Published online on: 01 May 2004

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Article

P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population

Hongbing Shen, Ana Solari, Xinru Wang, Zhengdong Zhang, Yaochu Xu, Liwei Wang, Xu Hu, Jiantao Guo, Qingyi Wei
Pages: 1115-1120
Published online on: 01 May 2004

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Article

Differential influence of pentoxifylline on murine colon adenocarcinoma- and melanoma-derived metastatic tumor development in lungs

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Marta Alicja Lazarczyk, Lukasz Milewski, Piotr Dziunycz, Piotr Skopinski, Jakub Golab
Pages: 1121-1125
Published online on: 01 May 2004

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Article

Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro

Maciej Kopec, Katarzyna Strusinska, Magdalena Legat, Marcin Makowski, Marek Jakobisiak, Jakub Golab
Pages: 1127-1131
Published online on: 01 May 2004

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Journal Cover
June-2026 Volume 55 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

E3 ubiquitin ligase RNF40: Structure, function and its context‑dependent roles in tumorigenesis (Review)

Zikun Wu, Hang Yang, Guanglong Chen, Weijie Zhao, Banghe Bao, Chai Luv, Wenpu Zhu, Faqiang Liu, Huihan Ai, Zhi Li
Article Number: 121
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 120
Published online on: 27 April 2026

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Article Open Access

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation

Nguyen Ngoc Thuy Tien, Han-Cheol Choe, Sang-Gun Ahn
Article Number: 119
Published online on: 24 April 2026

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Expression of Concern Open Access

[Expression of Concern] Pifithrin‑μ is efficacious against non‑small cell lung cancer via inhibition of heat shock protein 70

Yang Zhou, Jingping Ma, Jiahong Zhang, Li He, Jianhua Gong, Cong Long
Article Number: 118
Published online on: 22 April 2026

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Article Open Access

Inhibitory role of angiopoietin‑like 4 for cancer progression in oropharyngeal squamous cell carcinoma

Takuya Mikoshiba, Mariko Sekimizu, Nana Nakahara, Shin Saito, Keisuke Yoshihama, Ryoto Nagai, Takeyuki Kono, Hiroyuki Ozawa
Article Number: 117
Published online on: 20 April 2026

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Expression of Concern Open Access

[Expression of Concern] Adenovirus‑mediated truncated Bid overexpression induced by the Cre/LoxP system promotes the cell apoptosis of CD133+ ovarian cancer stem cells

Qifang Long, Ru Yang, Weixian Lu, Weipei Zhu, Jundong Zhou, Cui Zheng, Dongmei Zhou, Ling Yu, Jinchang Wu
Article Number: 116
Published online on: 15 April 2026

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Review Open Access

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review)

Hui Cheng, Guodong Zheng, Yuanyuan Yang, Chun Xu, Gusheng Tang, Chongmei Huang
Article Number: 115
Published online on: 15 April 2026

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Article Open Access

Mechanistic study of MUC3A in promoting progression of clear cell renal cell carcinoma via the JAK‑STAT pathway

Yongyang Yun, Xing Ji, Shuai Hu, Tianyu Wu, Yixiao Liu, Zheng Li, Zhoujie Sun, Peimin Zhou, Lei Yang, Wei Yu
Article Number: 114
Published online on: 14 April 2026

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Article Open Access

Perturbation of BRD4 and p300 activity suppresses super enhancer‑driven KLF6 expression in renal carcinoma

Nurul Nadia Mohamad Zamberi, Asmaa Y. Abuhamad, Siti Nur Hasanah Mohd Yusuf, Nur Qurratu Athirah A. Rahman, Mohamad Aimanuddin Mohtar, Saiful Effendi Syafruddin
Article Number: 113
Published online on: 14 April 2026

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Article Open Access

PINK1‑mediated mitophagy enhances breast cancer proliferation through metabolic reprogramming

Zong Jin Guo, Qian Yu, Rui Sha, Wei Li, Hui Juan Dai
Article Number: 112
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Metformin inhibits growth and sensitizes osteosarcoma cell lines to cisplatin through cell cycle modulation

Irene Quattrini, Amalia Conti, Laura Pazzaglia, Chiara Novello, Stefano Ferrari, Piero Picci, Maria Serena Benassi
Article Number: 111
Published online on: 08 April 2026

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Article Open Access

NF‑κB‑driven LUZP1 promotes metastasis and chemoresistance in head and neck squamous cell carcinoma

Chen-Yuan Lin, Ching-Yun Hsieh, Hsin-Chi Lan, Ching-Chan Lin, Tzu-Ting Chen, Wei-Chi Tseng, Yung-An Tsou, Wei-Chao Chang
Article Number: 110
Published online on: 07 April 2026

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Article Open Access

Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF

Shoichiro Nakajo, Mamoru Uemura, Hiroshi Kusafuka, Mao Osaki, Chikako Kusunoki, Nobuo Takiguchi, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 109
Published online on: 07 April 2026

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Retraction Open Access

[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD

Guoqiang Yu, Zhaohui Jia, Zhongling Dou
Article Number: 108
Published online on: 06 April 2026

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Review Open Access

Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review)

Shuo Li, Quan Ma, Keying Lian, Zhisheng Jiang, Yun Ma
Article Number: 107
Published online on: 02 April 2026

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Review Open Access

T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review)

Liuyang Zhang, Shun Ding, Dongzhui Chen, Benchi Cai, Zhonglin Mu
Article Number: 106
Published online on: 02 April 2026

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Retraction Open Access

[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer

Li Cheng, Dongmei Zhang, Wei Yan
Article Number: 105
Published online on: 02 April 2026

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Review Open Access

HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review)

Ju Zhang, Yifan Sun, Lanyu Wang, Jiayu Gu, Ye Hua, Jianfeng Shao, Ninghan Feng
Article Number: 104
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Article Number: 103
Published online on: 30 March 2026

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
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Review Open Access

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

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Published online on: 29 April 2026

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