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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2005 Volume 13 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Association of disease progression and poor overall survival with detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer

Thomas Bauernhofer, Sabine Zenahlik, Günter Hofmann, Marija Balic, Margit Resel, Renate Pirchmoser, Peter Regitnig, Peter Ambros, Nadia Dandachi, Hellmut Samonigg
Pages: 179-184
Published online on: 01 February 2005

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Article

UDP-glucuronosyltransferases 1A expression in human urinary bladder and colon cancer by immunohistochemistry

Laura Giuliani, Marco Ciotti, Antonella Stoppacciaro, Anna Pasquini, Ida Silvestri, Anna De Matteis, Luigi Frati, Anna-Maria Aglianò
Pages: 185-191
Published online on: 01 February 2005

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Article

Loss of the tight junction protein claudin 4 correlates with histological growth-pattern and differentiation in advanced gastric adenocarcinoma

Sang Kil Lee, Jung Moon, Seung Woo Park, Si Young Song, Jae Bock Chung, Jin Kyung Kang
Pages: 193-199
Published online on: 01 February 2005

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Article

High antitumor activity using intratumoral injection of plasmid DNA with mutant-type p27Kip1 gene following in vivo electroporation

Koji Harada, Supriatno, Shin-ichi Kawaguchi, Tomitaro Onoue, Yuichiro Kawashima, Hideo Yoshida, Mitsunobu Sato
Pages: 201-206
Published online on: 01 February 2005

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Article

Expression levels of Akt in nimesulide-treated squamous carcinoma cell lines of the head and neck

Laurenz Vormittag, Wolfgang Lamm, Boban M. Erovic, Cornelia Czembirek, Gabriela Kornek, Dietmar Thurnher
Pages: 207-210
Published online on: 01 February 2005

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Article

Suppression by incadronate of invasion and growth of A-375 human melanoma in mandible in nude mice

Yasushi Kitagawa, Toru Hiraga, Yoshiaki Yura, Toshiyuki Yoneda
Pages: 211-216
Published online on: 01 February 2005

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Article

Overexpression of constitutive signal transducer and activator of transcription 3 mRNA in cisplatin-resistant human non-small cell lung cancer cells

Kenji Ikuta, Kazu Takemura, Masaru Kihara, Masuhiro Nishimura, Nobuhiko Ueda, Shinsaku Naito, Eibai Lee, Eiji Shimizu, Aiko Yamauchi
Pages: 217-222
Published online on: 01 February 2005

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Article

Expression of endothelin-1 and endothelin-A and -B receptors in invasive bladder cancer

Christian Wülfing, Elke Eltze, Hansjürgen Piechota, Hassan Abol-Enein, Pia Wülfing, Marc-Eric Bode, Lothar Hertle, Karl-Dietrich Sievert
Pages: 223-228
Published online on: 01 February 2005

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Article

Immunohistochemical analysis of p53 and MIB-1 in tissue specimens obtained from endoscopic ultrasonography-guided fine needle aspiration biopsy for the diagnosis of solid pancreatic masses

Takao Itoi, Kazuo Takei, Atsushi Sofuni, Fumihide Itokawa, Takayoshi Tsuchiya, Toshio Kurihara, Kazuto Nakamura, Fuminori Moriyasu, Akihiko Tsuchida, Kazuhiko Kasuya
Pages: 229-234
Published online on: 01 February 2005

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Article

Impact of nuclear galectin-3 expression on histological differentiation and vascular invasion in patients with esophageal squamous cell carcinoma

Tomotaka Shibata, Tsuyoshi Noguchi, Shinsuke Takeno, Yoshiaki Takahashi, Shoichi Fumoto, Katsunobu Kawahara
Pages: 235-239
Published online on: 01 February 2005

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Article

Microsatellite instability and hMLH1 and hMSH2 expression analysis in soft tissue sarcomas

Ken-ichi Kawaguchi, Yoshinao Oda, Tomonari Takahira, Tsuyoshi Saito, Hidetaka Yamamoto, Chikashi Kobayashi, Sadafumi Tamiya, Shinya Oda, Yukihide Iwamoto, Masazumi Tsuneyoshi
Pages: 241-246
Published online on: 01 February 2005

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Article

Keratinocyte growth factor receptor expression in normal colorectal epithelial cells and differentiated type of colorectal cancer

Masanori Yoshino, Toshiyuki Ishiwata, Masanori Watanabe, Osamu Komine, Tetsuo Shibuya, Akira Tokunaga, Zenya Naito
Pages: 247-252
Published online on: 01 February 2005

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Article

Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1

M. Waheed Room, Vadim Ivanov, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 253-257
Published online on: 01 February 2005

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Article

Bcl-2 overexpression enhances in vitro sensitivity against docetaxel in non-small cell lung cancer

Yoshimasa Inoue, Masatoshi Gika, Tomohiro Abiko, Takahiko Oyama, Yuriko Saitoh, Hitoshi Yamazaki, Masato Nakamura, Yoshiyuki Abe, Masafumi Kawamura, Koichi Kobayashi
Pages: 259-264
Published online on: 01 February 2005

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Article

p53, K-ras, c-kit and β-catenin gene mutations in sinonasal NK/T-cell lymphoma in Korea and Japan

Tadashi Hongyo, Yoshihiko Hoshida, Shin-ichi Nakatsuka, Mukh Syaifudin, Shizuo Kojya, Woo-Ick Yang, Yoo-Hong Min, Heekyung Chan, Chan Hwan Kim, Yasuaki Harabuchi, Tetsuo Himi, Masao Inuyama, Katsuyuki Aozasa, Taisei Nomura
Pages: 265-271
Published online on: 01 February 2005

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Article

The hTERT protein as a marker for malignancy in meningiomas

J. P.O. Kalala, L. Maes, T. J. Thomas, C. Vandenbroecke, L. de Ridder
Pages: 273-277
Published online on: 01 February 2005

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Article

Periosteal Ewing's sarcoma treated by photodynamic therapy with acridine orange

Kakunoshin Yoshida, Katsuyuki Kusuzaki, Takao Matsubara, Akihiko Matsumine, Tadashi Kumamoto, Yoshihiro Komada, Norifumi Naka, Atsumasa Uchida
Pages: 279-282
Published online on: 01 February 2005

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Article

Randomised, open-label, phase II trial of paclitaxel, gemcitabine and cisplatin versus gemcitabine and cisplatin as first-line chemotherapy in advanced transitional cell carcinoma of the urothelium

Vito Lorusso, Enrico Crucitta, Nicola Silvestris, G. Rosati, L. Manzione, M. De Lena, S Palmeri, V Gebbia, S Mancarella, A Sobrero, G Pezzella, P Comella, A Mangiameli, D Muci
Pages: 283-287
Published online on: 01 February 2005

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Article

Inhibitory effects of OK-432 (Picibanil) on cellular proliferation and adhesive capacity of breast carcinoma cells

Yoshio Horii, Yuichi Iino, Michio Maemura, Jun Horiguchi, Yasuo Morishita
Pages: 289-294
Published online on: 01 February 2005

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Article

Metastasis of malignant peripheral nerve sheath tumor to free vascularized myocutaneous flap

Aki Fukuda, Katsuyuki Kusuzaki, Hitoshi Hirata, Takao Matsubara, Masashi Seto, Akihiko Matsumine, Atsumasa Uchida
Pages: 295-297
Published online on: 01 February 2005

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Article

Differential effects of RhoA signaling on anticancer agent-induced cell death

Won Ki Kang, Inkyoung Lee, Ukyoung Ko, Chaehwa Park
Pages: 299-304
Published online on: 01 February 2005

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Article

HER2 gene-amplified breast cancers with monosomy of chromosome 17 are poorly responsive to trastuzumab-based treatment

Mauro Risio, Laura Casorzo, Stefania Redana, Filippo Montemurro
Pages: 305-309
Published online on: 01 February 2005

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Article

Combined immunization with DNA and transduced tumor cells expressing mouse GM-CSF or IL-2

Simon Rittich, Martina Duskova, Jana Mackova, Dana Pokorna, Pavel Jinoch, Michal Smahel
Pages: 311-317
Published online on: 01 February 2005

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Article

Targeting human cancer cells with VEGF receptor-2-directed liposomes

Alma Rubio Demirovic, Cornelia Marty, Sandra Console, Steffen M. Zeisberger, Claudia Ruch, Rolf Jaussi, Reto A. Schwendener, Kurt Ballmer-Hofer
Pages: 319-324
Published online on: 31 January 2005

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Article

Development and application of a multiplex PCR procedure for the detection of DNA methylation in colorectal cancer

Charles Anacleto, Benedito Rossi, Ademar Lopes, Fernando A. Soares, José Cláudio C. Rocha, Otávia Caballero, Anamaria A. Camargo, Andrew J.G. Simpson, Sérgio D.J. Pena
Pages: 325-328
Published online on: 01 February 2005

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Article

Demonstration of the lapachol as a potential drug for reducing cancer metastasis

Ilana Teruszkin Balassiano, Sheila Alves de Paulo, Nathalie Henriques Silva, Maulori Curié Cabral, Maria da Gloria da Costa Carvalho
Pages: 329-333
Published online on: 01 February 2005

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Article

Low expression but infrequent genomic loss of the putative tumour suppressor DBCCR1 in astrocytoma

Christian Beetz, Stefan Brodoehl, Stephan Patt, Rolf Kalff, Thomas Deufel
Pages: 335-340
Published online on: 01 February 2005

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Article

Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential

Hideaki Miyake, Isao Hara, Kazuki Yamanaka, Mototsugu Muramaki, Martin Gleave, Hiroshi Eto
Pages: 341-345
Published online on: 01 February 2005

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Article

Chromosomal radiosensitivity in breast cancer patients: Influence of age of onset of the disease

Ans Baeyens, Rudy Van Den Broecke, Amin Makar, Hubert Thierens, Leo De Ridder, Anne Vral
Pages: 347-353
Published online on: 01 February 2005

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Article

Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: A case-control analysis in China

Hongbing Shen, Ana S. Newmann, Zhibin Hu, Zhengdong Zhang, Yaochu Xu, Liwei Wang, Xu Hu, Jiangtao Guo, Xinru Wang, Qingyi Wei
Pages: 355-360
Published online on: 01 February 2005

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Article

Lymph node revealing solution in gastric carcinoma does not provide upstaging of the N-status

Thomas Luebke, Stephan E. Baldus, Thomas K. Zirbes, Thai D.C. Pham, Paul M. Schneider, Hans P. Dienes, Arnulf H. Hölscher, Stefan P. Mönig
Pages: 361-365
Published online on: 01 February 2005

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Article

Characterization of KIF12 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 367-370
Published online on: 01 February 2005

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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Correction Open Access

[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Review Open Access

Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Article Open Access

Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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Article Open Access

POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Article

Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Review Open Access

Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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Article Open Access

TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Review Open Access

Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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Article Open Access

High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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