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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2010 Volume 37 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Behind the scenes: Unravelling the molecular mechanisms of p53 target gene selectivity (Review)

Leonie Smeenk, Marion Lohrum
Pages: 1061-1070
Published online on: 01 November 2010

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Review

Augmentation of the ubiquitin-mediated proteolytic system by F-box and additional motif-containing proteins (Review)

Kazuyuki Sato, Kenichi Yoshida
Pages: 1071-1076
Published online on: 01 November 2010

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Article Open Access

Somatostatin analogue inhibits the mobility of prostate carcinoma cells: A new therapeutic method for advanced prostate carcinoma

Xiaoyan Tang, Susumu Takekoshi, Johbu Itoh, Shinobu Umemura, Sunao Shoji, Toshiro Terachi, Robert Yoshiyuki Osamura
Pages: 1077-1083
Published online on: 01 November 2010

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Article Open Access

Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis

Masahiko Ajiro, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura
Pages: 1085-1093
Published online on: 01 November 2010

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Article

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

Soichi Iwai, Atsuko Yonekawa, Chie Harada, Masakazu Hamada, Wataru Katagiri, Mituhiro Nakazawa, Yoshiaki Yura
Pages: 1095-1103
Published online on: 01 November 2010

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Article

Clinical significance of ASB9 in human colorectal cancer

Masayoshi Tokuoka, Norikatsu Miyoshi, Toshiki Hitora, Koshi Mimori, Fumiaki Tanaka, Koichi Shibata, Hideshi Ishii, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 1105-1111
Published online on: 01 November 2010

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Article

Prediction of the response to chemotherapy in advanced esophageal cancer by gene expression profiling of biopsy samples

Masaaki Motoori, Ichiro Takemasa, Makoto Yamasaki, Takamichi Komori, Atsushi Takeno, Hiroshi Miyata, Shuji Takiguchi, Yoshiyuki Fujiwara, Takushi Yasuda, Masahiko Yano, Nariaki Matsuura, Kenichi Matsubara, Morito Monden, Masaki Mori, Yuichiro Doki
Pages: 1113-1120
Published online on: 01 November 2010

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Article

Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity

Akihiro Inoue, Hisaaki Takahashi, Hironobu Harada, Shohei Kohno, Shiro Ohue, Kana Kobayashi, Hajime Yano, Junya Tanaka, Takanori Ohnishi
Pages: 1121-1131
Published online on: 01 November 2010

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Article

Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53

Shiho Ohnishi, Manabu Futamura, Hiroki Kamino, Yasuyuki Nakamura, Noriaki Kitamura, Yuji Miyamoto, Takafumi Miyamoto, Daisuke Shinogi, Olga Goda, Hirofumi Arakawa
Pages: 1133-1141
Published online on: 01 November 2010

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Article

Mechanisms behind COX-1 and COX-2 inhibition of tumor growth in vivo

Hans Axelsson, Christina Lönnroth, Marianne Andersson, Kent Lundholm
Pages: 1143-1152
Published online on: 01 November 2010

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Article

Abnormal expression of Endoglin and its receptor complex (TGF-β1 and TGF-β receptor II) as early angiogenic switch indicator in premalignant lesions of the colon mucosa

Graziella Bellone, Claudia Gramigni, Barbara Vizio, Francesco A. Mauri, Adriana Prati, Dino Solerio, Luca Dughera, Enrico Ruffini, Guido Gasparri, Michele Camandona
Pages: 1153-1165
Published online on: 01 November 2010

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Article

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

Antonino B. D'Assoro, Alexey Leontovich, Angela Amato, Jennifer R. Ayers-Ringler, Cosima Quatraro, Kari Hafner, Robert B. Jenkins, Massimo Libra, James Ingle, Franca Stivala, Evanthia Galanis, Jeffrey L. Salisbury
Pages: 1167-1176
Published online on: 01 November 2010

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Article

Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway

Min Jung Kim, Tae Hwa Lee, Sung Han Kim, Yeon-Joo Choi, Jeonghoon Heo, Young-Ho Kim
Pages: 1177-1185
Published online on: 01 November 2010

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Article

Amifostine enhancement of the anti-cancer effects of paclitaxel in endometrial cancer is TP53-dependent

Wentao Luo, Fan Wu, Ruba Elmaoued, Brandon B. Beck, Edgar Fischer, Xiangbing Meng, Kimberly K. Leslie, Donghai Dai
Pages: 1187-1194
Published online on: 01 November 2010

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Article

Parity is associated with an expanded macrophage population in the mammary gland

Wei Zhao, Clinton J. Grubbs, Ronald K. Myers, Marit Nilsen-Hamilton
Pages: 1195-1202
Published online on: 01 November 2010

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Article

Optimization studies for the coupling of bispecific antibodies to viral anchor molecules of a tumor vaccine

Philippe Fournier, Maximilian Aigner, Volker Schirrmacher
Pages: 1203-1217
Published online on: 01 November 2010

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Article

Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer

Cristiana Lo Nigro, Martino Monteverde, Michela Riba, Laura Lattanzio, Federica Tonissi, Ornella Garrone, Abdelhamid Heouaine, Fabio Gallo, Marcello Ceppi, Felice Borghi, Alberto Comino, Marco Merlano
Pages: 1219-1228
Published online on: 01 November 2010

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Article

Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372

Wai Kien Yip, Sarot Cheenpracha, Leng Chee Chang, Coy Choke Ho, Heng Fong Seow
Pages: 1229-1241
Published online on: 01 November 2010

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Article

Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways

Jehn-Hwa Kuo, Yung-Lin Chu, Jai-Sing Yang, Jing-Pin Lin, Kuang-Chi Lai, Hsiu-Maan Kuo, Te-Chun Hsia, Jing-Gung Chung
Pages: 1243-1250
Published online on: 01 November 2010

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Article

Angiotensin II induces tumor progression and fibrosis in intrahepatic cholangiocarcinoma through an interaction with hepatic stellate cells

Koichi Okamoto, Hidehiro Tajima, Tetsuo Ohta, Shinichi Nakanuma, Hironori Hayashi, Hisatoshi Nakagawara, Ichiro Onishi, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Masato Kayahara, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki
Pages: 1251-1259
Published online on: 01 November 2010

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Article

Down-regulation of CacyBP is associated with poor prognosis and the effects on COX-2 expression in breast cancer

Fang Nie, Xiao-Ling Yu, Xiao-Ge Wang, Yu-Fu Tang, Ling-Ling Wang, Lie Ma
Pages: 1261-1269
Published online on: 01 November 2010

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Article Open Access

Comparative proteomic analysis of the ribosomes in 5-fluorouracil resistance of a human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis

Kosei Kimura, Akira Wada, Masami Ueta, Akihiko Ogata, Satoru Tanaka, Akiko Sakai, Hideji Yoshida, Hideo Fushitani, Akiko Miyamoto, Masakazu Fukushima, Toshio Uchiumi, Nobuhiko Tanigawa
Pages: 1271-1278
Published online on: 01 November 2010

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Article

Neuroblastoma cells can be classified according to glycosphingolipid expression profiles identified by liquid chromatography-tandem mass spectrometry

Tomonori Kaneko, Hajime Okita, Hideki Nakajima, Kazutoshi Iijima, Nao Ogasawara, Yoshitaka Miyagawa, Yohko U. Katagiri, Atsuko Nakagawa, Nobutaka Kiyokawa, Toshinori Sato, Junichiro Fujimoto
Pages: 1279-1288
Published online on: 01 November 2010

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Article

Calpain is involved in cisplatin-induced endothelial injury in an in vitro three-dimensional blood vessel model

Ryoji Eguchi, Yoshihiro Fujimori, Toshiro Ohta, Kazuhiro Kunimasa, Takashi Nakano
Pages: 1289-1296
Published online on: 01 November 2010

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Article

Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells

Catharine A. Street, Alissa A. Routhier, Carrie Spencer, Ashley L. Perkins, Katherine Masterjohn, Alexander Hackathorn, John Montalvo, Emily A. Dennstedt, Brad A. Bryan
Pages: 1297-1305
Published online on: 01 November 2010

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Article

Parthenolide treatment activates stress signaling proteins in high-risk acute lymphoblastic leukemia cells with chromosomal translocation t(4;11)

Susan J. Zunino, David H. Storms, Jonathan M. Ducore
Pages: 1307-1313
Published online on: 01 November 2010

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Article

Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level

Zaozao Wang, Mei Liu, Hongxia Zhu, Wei Zhang, Shun He, Chenfei Hu, Lanping Quan, Jinfeng Bai, Ningzhi Xu
Pages: 1315-1321
Published online on: 01 November 2010

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Article

Suppression of RIZ in biologically unfavourable neuroblastomas

Janos Geli, Nimrod Kiss, Per Kogner, Catharina Larsson
Pages: 1323-1330
Published online on: 01 November 2010

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Article

Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells

Jiumao Lin, Youqin Chen, Lihui Wei, Xuzhen Chen, Wei Xu, Zhenfeng Hong, Thomas J. Sferra, Jun Peng
Pages: 1331-1338
Published online on: 01 November 2010

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Article

Increased Cul1 expression promotes melanoma cell proliferation through regulating p27 expression

Guangdi Chen, Gang Li
Pages: 1339-1344
Published online on: 01 November 2010

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Article

Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: The role of reactive oxygen species and Akt

Xiao-Chun Zhao, Li Tian, Jian-Guo Cao, Fei Liu
Pages: 1345-1352
Published online on: 01 November 2010

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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