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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2010 Volume 37 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Behind the scenes: Unravelling the molecular mechanisms of p53 target gene selectivity (Review)

Leonie Smeenk, Marion Lohrum
Pages: 1061-1070
Published online on: 01 November 2010

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Review

Augmentation of the ubiquitin-mediated proteolytic system by F-box and additional motif-containing proteins (Review)

Kazuyuki Sato, Kenichi Yoshida
Pages: 1071-1076
Published online on: 01 November 2010

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Article Open Access

Somatostatin analogue inhibits the mobility of prostate carcinoma cells: A new therapeutic method for advanced prostate carcinoma

Xiaoyan Tang, Susumu Takekoshi, Johbu Itoh, Shinobu Umemura, Sunao Shoji, Toshiro Terachi, Robert Yoshiyuki Osamura
Pages: 1077-1083
Published online on: 01 November 2010

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Article Open Access

Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis

Masahiko Ajiro, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura
Pages: 1085-1093
Published online on: 01 November 2010

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Article

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

Soichi Iwai, Atsuko Yonekawa, Chie Harada, Masakazu Hamada, Wataru Katagiri, Mituhiro Nakazawa, Yoshiaki Yura
Pages: 1095-1103
Published online on: 01 November 2010

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Article

Clinical significance of ASB9 in human colorectal cancer

Masayoshi Tokuoka, Norikatsu Miyoshi, Toshiki Hitora, Koshi Mimori, Fumiaki Tanaka, Koichi Shibata, Hideshi Ishii, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 1105-1111
Published online on: 01 November 2010

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Article

Prediction of the response to chemotherapy in advanced esophageal cancer by gene expression profiling of biopsy samples

Masaaki Motoori, Ichiro Takemasa, Makoto Yamasaki, Takamichi Komori, Atsushi Takeno, Hiroshi Miyata, Shuji Takiguchi, Yoshiyuki Fujiwara, Takushi Yasuda, Masahiko Yano, Nariaki Matsuura, Kenichi Matsubara, Morito Monden, Masaki Mori, Yuichiro Doki
Pages: 1113-1120
Published online on: 01 November 2010

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Article

Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity

Akihiro Inoue, Hisaaki Takahashi, Hironobu Harada, Shohei Kohno, Shiro Ohue, Kana Kobayashi, Hajime Yano, Junya Tanaka, Takanori Ohnishi
Pages: 1121-1131
Published online on: 01 November 2010

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Article

Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53

Shiho Ohnishi, Manabu Futamura, Hiroki Kamino, Yasuyuki Nakamura, Noriaki Kitamura, Yuji Miyamoto, Takafumi Miyamoto, Daisuke Shinogi, Olga Goda, Hirofumi Arakawa
Pages: 1133-1141
Published online on: 01 November 2010

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Article

Mechanisms behind COX-1 and COX-2 inhibition of tumor growth in vivo

Hans Axelsson, Christina Lönnroth, Marianne Andersson, Kent Lundholm
Pages: 1143-1152
Published online on: 01 November 2010

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Article

Abnormal expression of Endoglin and its receptor complex (TGF-β1 and TGF-β receptor II) as early angiogenic switch indicator in premalignant lesions of the colon mucosa

Graziella Bellone, Claudia Gramigni, Barbara Vizio, Francesco A. Mauri, Adriana Prati, Dino Solerio, Luca Dughera, Enrico Ruffini, Guido Gasparri, Michele Camandona
Pages: 1153-1165
Published online on: 01 November 2010

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Article

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

Antonino B. D'Assoro, Alexey Leontovich, Angela Amato, Jennifer R. Ayers-Ringler, Cosima Quatraro, Kari Hafner, Robert B. Jenkins, Massimo Libra, James Ingle, Franca Stivala, Evanthia Galanis, Jeffrey L. Salisbury
Pages: 1167-1176
Published online on: 01 November 2010

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Article

Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway

Min Jung Kim, Tae Hwa Lee, Sung Han Kim, Yeon-Joo Choi, Jeonghoon Heo, Young-Ho Kim
Pages: 1177-1185
Published online on: 01 November 2010

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Article

Amifostine enhancement of the anti-cancer effects of paclitaxel in endometrial cancer is TP53-dependent

Wentao Luo, Fan Wu, Ruba Elmaoued, Brandon B. Beck, Edgar Fischer, Xiangbing Meng, Kimberly K. Leslie, Donghai Dai
Pages: 1187-1194
Published online on: 01 November 2010

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Article

Parity is associated with an expanded macrophage population in the mammary gland

Wei Zhao, Clinton J. Grubbs, Ronald K. Myers, Marit Nilsen-Hamilton
Pages: 1195-1202
Published online on: 01 November 2010

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Article

Optimization studies for the coupling of bispecific antibodies to viral anchor molecules of a tumor vaccine

Philippe Fournier, Maximilian Aigner, Volker Schirrmacher
Pages: 1203-1217
Published online on: 01 November 2010

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Article

Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer

Cristiana Lo Nigro, Martino Monteverde, Michela Riba, Laura Lattanzio, Federica Tonissi, Ornella Garrone, Abdelhamid Heouaine, Fabio Gallo, Marcello Ceppi, Felice Borghi, Alberto Comino, Marco Merlano
Pages: 1219-1228
Published online on: 01 November 2010

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Article

Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372

Wai Kien Yip, Sarot Cheenpracha, Leng Chee Chang, Coy Choke Ho, Heng Fong Seow
Pages: 1229-1241
Published online on: 01 November 2010

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Article

Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways

Jehn-Hwa Kuo, Yung-Lin Chu, Jai-Sing Yang, Jing-Pin Lin, Kuang-Chi Lai, Hsiu-Maan Kuo, Te-Chun Hsia, Jing-Gung Chung
Pages: 1243-1250
Published online on: 01 November 2010

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Article

Angiotensin II induces tumor progression and fibrosis in intrahepatic cholangiocarcinoma through an interaction with hepatic stellate cells

Koichi Okamoto, Hidehiro Tajima, Tetsuo Ohta, Shinichi Nakanuma, Hironori Hayashi, Hisatoshi Nakagawara, Ichiro Onishi, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Masato Kayahara, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki
Pages: 1251-1259
Published online on: 01 November 2010

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Article

Down-regulation of CacyBP is associated with poor prognosis and the effects on COX-2 expression in breast cancer

Fang Nie, Xiao-Ling Yu, Xiao-Ge Wang, Yu-Fu Tang, Ling-Ling Wang, Lie Ma
Pages: 1261-1269
Published online on: 01 November 2010

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Article Open Access

Comparative proteomic analysis of the ribosomes in 5-fluorouracil resistance of a human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis

Kosei Kimura, Akira Wada, Masami Ueta, Akihiko Ogata, Satoru Tanaka, Akiko Sakai, Hideji Yoshida, Hideo Fushitani, Akiko Miyamoto, Masakazu Fukushima, Toshio Uchiumi, Nobuhiko Tanigawa
Pages: 1271-1278
Published online on: 01 November 2010

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Article

Neuroblastoma cells can be classified according to glycosphingolipid expression profiles identified by liquid chromatography-tandem mass spectrometry

Tomonori Kaneko, Hajime Okita, Hideki Nakajima, Kazutoshi Iijima, Nao Ogasawara, Yoshitaka Miyagawa, Yohko U. Katagiri, Atsuko Nakagawa, Nobutaka Kiyokawa, Toshinori Sato, Junichiro Fujimoto
Pages: 1279-1288
Published online on: 01 November 2010

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Article

Calpain is involved in cisplatin-induced endothelial injury in an in vitro three-dimensional blood vessel model

Ryoji Eguchi, Yoshihiro Fujimori, Toshiro Ohta, Kazuhiro Kunimasa, Takashi Nakano
Pages: 1289-1296
Published online on: 01 November 2010

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Article

Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells

Catharine A. Street, Alissa A. Routhier, Carrie Spencer, Ashley L. Perkins, Katherine Masterjohn, Alexander Hackathorn, John Montalvo, Emily A. Dennstedt, Brad A. Bryan
Pages: 1297-1305
Published online on: 01 November 2010

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Article

Parthenolide treatment activates stress signaling proteins in high-risk acute lymphoblastic leukemia cells with chromosomal translocation t(4;11)

Susan J. Zunino, David H. Storms, Jonathan M. Ducore
Pages: 1307-1313
Published online on: 01 November 2010

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Article

Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level

Zaozao Wang, Mei Liu, Hongxia Zhu, Wei Zhang, Shun He, Chenfei Hu, Lanping Quan, Jinfeng Bai, Ningzhi Xu
Pages: 1315-1321
Published online on: 01 November 2010

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Article

Suppression of RIZ in biologically unfavourable neuroblastomas

Janos Geli, Nimrod Kiss, Per Kogner, Catharina Larsson
Pages: 1323-1330
Published online on: 01 November 2010

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Article

Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells

Jiumao Lin, Youqin Chen, Lihui Wei, Xuzhen Chen, Wei Xu, Zhenfeng Hong, Thomas J. Sferra, Jun Peng
Pages: 1331-1338
Published online on: 01 November 2010

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Article

Increased Cul1 expression promotes melanoma cell proliferation through regulating p27 expression

Guangdi Chen, Gang Li
Pages: 1339-1344
Published online on: 01 November 2010

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Article

Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: The role of reactive oxygen species and Akt

Xiao-Chun Zhao, Li Tian, Jian-Guo Cao, Fei Liu
Pages: 1345-1352
Published online on: 01 November 2010

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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