Journal Articles
Review
MALDI TOF imaging mass spectrometry in clinical pathology: A valuable tool for cancer diagnostics (Review)
Jörg Kriegsmann, Mark Kriegsmann, Rita Casadonte
Pages: 893-906 Published online on: 04 December 2014
Review
Hsp90 inhibitor as a sensitizer of cancer cells to different therapies (Review)
Zuzana Solárová, Ján Mojžiš, Peter Solár
Pages: 907-926 Published online on: 10 December 2014
Review
Identification of dysregulated microRNAs in triple-negative breast cancer (Review)
Fang Yang, Wenwen Zhang, Yan Shen, Xiaoxiang Guan
Pages: 927-932 Published online on: 08 January 2015
Review
Role of TGFβ in regulation of the tumor microenvironment and drug delivery (Review)
Panagiotis Papageorgis, Triantafyllos Stylianopoulos
Pages: 933-943 Published online on: 07 January 2015
Article
An accurate prognostic staging system for hepatocellular carcinoma patients after curative hepatectomy
Yukio Tokumitsu, Takao Tamesa, Satoshi Matsukuma, Noriaki Hashimoto, Yoshinari Maeda, Yoshihiro Tokuhisa, Kazuhiko Sakamoto, Tomio Ueno, Shoichi Hazama, Hiroyuki Ogihara, Yusuke Fujita, Yoshihiko Hamamoto, Masaaki Oka, Norio Iizuka
Pages: 944-952 Published online on: 17 December 2014
Article
Diagnostic value of immunoglobulin κ light chain gene rearrangement analysis in B-cell lymphomas
Ira Kokovic, Barbara Jezersek Novakovic, Srdjan Novakovic
Pages: 953-962 Published online on: 09 December 2014
Article
Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells
Naoko Wada, Yawara Kawano, Shiho Fujiwara, Yoshitaka Kikukawa, Yutaka Okuno, Masayoshi Tasaki, Mitsuharu Ueda, Yukio Ando, Kazuya Yoshinaga, Masaki Ri, Shinsuke Iida, Takayuki Nakashima, Yukimasa Shiotsu, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 963-972 Published online on: 19 December 2014
Article
Sialylation by β‑galactoside α‑2,6‑sialyltransferase and N‑glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma
Osamu Suzuki, Masafumi Abe, Yuko Hashimoto
Pages: 973-980 Published online on: 07 January 2015
Article
Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway
Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Pages: 981-988 Published online on: 08 January 2015
Article
Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: Retrospective and in vitro studies
Hiroki Izumi, Hirokazu Touge, Tadashi Igishi, Haruhiko Makino, Shizuka Nishii‑Ito, Miyako Takata, Hirofumi Nakazaki, Yasuto Ueda, Shingo Matsumoto, Masahiro Kodani, Jun Kurai, Kenichi Takeda, Tomohiro Sakamoto, Masaaki Yanai, Natsumi Tanaka, Chaitanya S. Nirodi, Eiji Shimizu
Pages: 989-998 Published online on: 07 January 2015
Article
FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma
Naoyuki Okabe, Junji Ezaki, Takumi Yamaura, Satoshi Muto, Jun Osugi, Hirosumi Tamura, Jun‑Ichi Imai, Emi Ito, Yuka Yanagisawa, Reiko Honma, Mitsukazu Gotoh, Shinya Watanabe, Satoshi Waguri, Hiroyuki Suzuki
Pages: 999-1006 Published online on: 07 January 2015
Article
Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways
Guanmin Meng, Wei Wang, Kequn Chai, Suwen Yang, Fangqiong Li, Kai Jiang
Pages: 1007-1017 Published online on: 07 January 2015
Article
Gastric cancer cell proliferation is suppressed by frizzled-2 short hairpin RNA
Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 1018-1024 Published online on: 09 January 2015
Article
Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer
Akihiro Kogita, Yosuke Togashi, Hidetoshi Hayashi, Eri Banno, Masato Terashima, Marco A. De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yoshifumi Takeyama, Kiyotaka Okuno, Kazuhiko Nakagawa, Kazuto Nishio
Pages: 1025-1030 Published online on: 15 December 2014
Article
Overexpression of miR‑145 in U87 cells reduces glioma cell malignant phenotype and promotes survival after in vivo implantation
Yong Lu, Michael Chopp, Xuguang Zheng, Mark Katakowski, Ding Wang, Elise Fraser, Monique Nguyen, Feng Jiang
Pages: 1031-1038 Published online on: 23 December 2014
Article
Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma
Hiroko Mataki, Naohiko Seki, Takeshi Chiyomaru, Hideki Enokida, Yusuke Goto, Tomohiro Kumamoto, Kentaro Machida, Keiko Mizuno, Masayuki Nakagawa, Hiromasa Inoue
Pages: 1039-1050 Published online on: 18 December 2014
Article
Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells
Shaobo Ke, Fuxiang Zhou, Hui Yang, Yuehua Wei, Jun Gong, Zijie Mei, Lin Wu, Haijun Yu, Yunfeng Zhou
Pages: 1051-1058 Published online on: 10 December 2014
Article
Usefulness of microRNA‑375 as a prognostic and therapeutic tool in esophageal squamous cell carcinoma
Yuka Isozaki, Isamu Hoshino, Yasunori Akutsu, Naoyuki Hanari, Mikito Mori, Takanori Nishimori, Kentaro Murakami, Naoki Akanuma, Nobuyoshi Takeshita, Tetsuro Maruyama, Takeshi Toyozumi, Masahiko Takahashi, Hiroshi Suito, Hisahiro Matsubara
Pages: 1059-1066 Published online on: 09 December 2014
Article
Arsenic trioxide-induced cytotoxicity in small cell lung cancer via altered redox homeostasis and mitochondrial integrity
Chun-Yan Zheng, Sze-Kwan Lam, Yuan-Yuan Li, James Chung-Man Ho
Pages: 1067-1078 Published online on: 09 January 2015
Article
Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivity
Timothy D. Rohrbach, John S. Jarboe, Joshua C. Anderson, Hoa Q. Trummell, Patricia H. Hicks, Alice N. Weaver, Eddy S. Yang, Robert A. Oster, Jessy S. Deshane, Chad Steele, Gene P. Siegal, James A. Bonner, Christopher D. Willey
Pages: 1079-1088 Published online on: 17 December 2014
Article
Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma
Tri Budi Hartomo, Thi Van Huyen Pham, Nobuyuki Yamamoto, Satoshi Hirase, Daiichiro Hasegawa, Yoshiyuki Kosaka, Masafumi Matsuo, Akira Hayakawa, Yasuhiro Takeshima, Kazumoto Iijima, Hisahide Nishio, Noriyuki Nishimura
Pages: 1089-1098 Published online on: 17 December 2014
Article
Pancreatic ductal adenocarcinoma cell lines display a plastic ability to bi‑directionally convert into cancer stem cells
Elisa Dalla Pozza, Ilaria Dando, Giulia Biondani, Jessica Brandi, Chiara Costanzo, Elisa Zoratti, Matteo Fassan, Federico Boschi, Davide Melisi, Daniela Cecconi, Maria Teresa Scupoli, Aldo Scarpa, Marta Palmieri
Pages: 1099-1108 Published online on: 12 December 2014
Article
CCL18 promotes epithelial-mesenchymal transition, invasion and migration of pancreatic cancer cells in pancreatic ductal adenocarcinoma
Fanbin Meng, Wan Li, Changling Li, Zhigang Gao, Kejian Guo, Shaowei Song
Pages: 1109-1120 Published online on: 10 December 2014
Article
Parthenolide enhances sensitivity of colorectal cancer cells to TRAIL by inducing death receptor 5 and promotes TRAIL-induced apoptosis
Se-Lim Kim, Yu-Chuan Liu, Young Ran Park, Seung Young Seo, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Dae-Ghon Kim, Sang-Wook Kim
Pages: 1121-1130 Published online on: 12 December 2014
Article
Genistein exerts growth inhibition on human osteosarcoma MG-63 cells via PPARγ pathway Corrigendum in /10.3892/ijo.2024.5635
Mingzhi Song, Xiliang Tian, Ming Lu, Xianbin Zhang, Kai Ma, Zhichao Lv, Zhenxing Wang, Yang Hu, Chong Xun, Zhen Zhang, Shouyu Wang
Pages: 1131-1140 Published online on: 09 January 2015
Article
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role
Xiaojin Zhang, Xiaoai Zhao, Shan Shao, Xiaoxiao Zuo, Qian Ning, Minna Luo, Shanzhi Gu, Xinhan Zhao
Pages: 1141-1148 Published online on: 23 December 2014
Article
Luteolin acts as a radiosensitizer in non‑small cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade
Hyun‑Ji Cho, Kwang‑Chul Ahn, Jae Yeon Choi, Sang‑Gu Hwang, Wun‑Jae Kim, Hong‑Duck Um, Jong Kuk Park
Pages: 1149-1158 Published online on: 09 January 2015
Article
Evaluation of a 64Cu‑labeled 1,4,7‑triazacyclononane, 1‑glutaric acid‑4,7 acetic acid (NODAGA)‑galactose‑bombesin analogue as a PET imaging probe in a gastrin‑releasing peptide receptor‑expressing prostate cancer xenograft model
Min Hwan Kim, Ji Ae Park, Sang‑Keun Woo, Kyo Chul Lee, Gwang Il An, Byoung Soo Kim, Kwang Il Kim, Tae Sup Lee, Chan Wha Kim, Kyeong Min Kim, Joo Hyun Kang, Yong Jin Lee
Pages: 1159-1168 Published online on: 09 January 2015
Article
miR-221-induced PUMA silencing mediates immune evasion of bladder cancer cells
Bin Fu, Yibing Wang, Xiali Zhang, Bin Lang, Xiaocheng Zhou, Xiaoyuan Xu, Tao Zeng, Weipeng Liu, Xu Zhang, Ju Guo, Gongxian Wang
Pages: 1169-1180 Published online on: 13 January 2015
Article
Mathematical analysis predicts imbalanced IDH1/2 expression associates with 2-HG-inactivating β-oxygenation pathway in colorectal cancer
Jun Koseki, Hugh Colvin, Takahito Fukusumi, Naohiro Nishida, Masamitsu Konno, Koichi Kawamoto, Kenta Tsunekuni, Hidetoshi Matsui, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 1181-1191 Published online on: 12 January 2015
Article
5-Azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation
Mathias Füller, Miriam Klein, Eva Schmidt, Christian Rohde, Stefanie Göllner, Isabell Schulze, Jiang Qianli, Wolfgang E. Berdel, Bayram Edemir, Carsten Müller-Tidow, Petra Tschanter
Pages: 1192-1204 Published online on: 10 December 2014
Article
The role of IGFBP-5 in mediating the anti-proliferation effect of tetrandrine in human colon cancer cells
Ke Wu, Mi Zhou, Qiu-Xiang Wu, Shuang-Xu Yuan, Dong-Xu Wang, Jie-Li Jin, Jun Huang, Jun-Qin Yang, Wen-Juan Sun, Li-Hua Wan, Bai-Cheng He
Pages: 1205-1213 Published online on: 17 December 2014
Article
The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells
Antonia Bellizzi, Maria Raffaella Greco, Rosa Rubino, Angelo Paradiso, Stefania Forciniti, Katrine Zeeberg, Rosa Angela Cardone, Stephan Joel Reshkin
Pages: 1214-1224 Published online on: 19 December 2014
Article
Anti-metastasis efficacy and safety of non-anticoagulant heparin derivative versus low molecular weight heparin in surgical pancreatic cancer models
Reem Alyahya, Thangirala Sudha, Michael Racz, Steven C. Stain, Shaker A. Mousa
Pages: 1225-1231 Published online on: 19 December 2014
Article
Downregulation of UHRF1 promotes EMT via inducing CXCR4 in human cancer cells
Yi-Deun Jung, Jae-Woong Shim, Seong-Joon Park, Si Ho Choi, Kwangmo Yang, Kyu Heo, Moon-Taek Park
Pages: 1232-1242 Published online on: 30 December 2014
Article
CHST11 gene expression and DNA methylation in breast cancer
Damir Herman, Tatiana I. Leakey, Alice Behrens, Aiwei Yao-Borengasser, Craig A. Cooney, Fariba Jousheghany, Bounleut Phanavanh, Eric R. Siegel, A. Mazin Safar, Soheila Korourian, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi
Pages: 1243-1251 Published online on: 09 January 2015
Article
Decreased expression of carbonyl reductase 1 promotes ovarian cancer growth and proliferation
Yuki Osawa, Yoshihito Yokoyama, Tatsuhiko Shigeto, Masayuki Futagami, Hideki Mizunuma
Pages: 1252-1258 Published online on: 30 December 2014
Article
Relationship between in vitro drug sensitivity and clinical response of patients to treatment in chronic lymphocytic leukemia
Małgorzata Rogalińska, Jerzy Z. Błoński, Paweł Góralski, Ewa Wawrzyniak, Mariusz Hartman, Aneta Rogalska, Paweł Robak, Aneta Koceva‑Chyła, Henryk Piekarski, Tadeusz Robak, Zofia M. Kiliańska
Pages: 1259-1267 Published online on: 08 January 2015
Article
A cisplatin‑incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity
Joohee Jung, Seong‑Yun Jeong, Seok Soon Park, Seol Hwa Shin, Eun Jin Ju, Jinhyang Choi, Jaesook Park, Jae Hee Lee, Inki Kim, Young‑Ah Suh, Jung Jin Hwang, Shun'ichi Kuroda, Jung Shin Lee, Si Yeol Song, Eun Kyung Choi
Pages: 1268-1274 Published online on: 22 December 2014
Article
Glypican-3 promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through ERK signaling pathway
Yongle Wu, Hui Liu, Honglei Weng, Xin Zhang, Peng Li, Chun-Lei Fan, Bing Li, Pei-Ling Dong, Lei Li, Steven Dooley, Hui-Guo Ding
Pages: 1275-1285 Published online on: 09 January 2015
Article
Autophagy facilitates the development of resistance to the tumor necrosis factor superfamily member TRAIL in breast cancer
Shangge Lv, Xiaolong Wang, Ning Zhang, Mingjuan Sun, Wenwen Qi, Yaming Li, Qifeng Yang
Pages: 1286-1294 Published online on: 30 December 2014
Article
Adenovirus-mediated ING4/PTEN double tumor suppressor gene co-transfer modified by RGD enhances antitumor activity in human nasopharyngeal carcinoma cells
Yihong Wang, Jicheng Yang, Weihua Sheng, Yufeng Xie, Jisheng Liu
Pages: 1295-1303 Published online on: 08 January 2015
Article
Bcl2L12 with a BH3-like domain in regulating apoptosis and TMZ-induced autophagy: A prospective combination of ABT-737 and TMZ for treating glioma
Ming-Chang Yang, Joon-Khim Loh, Yi-Yang Li, Wen-Sheng Huang, Chia-Hua Chou, Jiin-Tsuey Cheng, Yeng-Tseng Wang, Ann-Shung Lieu, Shen-Long Howng, Yi-Ren Hong, An-Kuo Chou
Pages: 1304-1316 Published online on: 13 January 2015
Article
Silencing HO-1 sensitizes SKM-1 cells to apoptosis induced by low concentration 5-azacytidine through enhancing p16 demethylation
Ping Wang, Dan Ma, Jishi Wang, Qin Fang, Rui Gao, Weibing Wu, Tangsheng Lu, Lu Cao
Pages: 1317-1327 Published online on: 12 January 2015
Article
Overexpression of PGC‑1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein
Sung-Won Shin, Seong-Hoon Yun, Eun-Seon Park, Jin-Sook Jeong, Jong-Young Kwak, Joo-In Park
Pages: 1328-1342 Published online on: 12 January 2015
Article
Rac1 is correlated with aggressiveness and a potential therapeutic target for gastric cancer
Jun Ji, Xiaojing Feng, Min Shi, Qu Cai, Yingyan Yu, Zhenggang Zhu, Jun Zhang
Pages: 1343-1353 Published online on: 13 January 2015
Article
LH-RH analogues in the treatment of young women with early breast cancer: Long-term follow-up of a phase II study
Francesco Recchia, Stefano Necozione, Massimo Bratta, Michele Rosselli, Gabriele Guerriero, Silvio Rea
Pages: 1354-1360 Published online on: 30 December 2014
Article
Importance of circulating tumor cells in newly diagnosed colorectal cancer
Guus van Dalum, Gerrit-Jan Stam, Loes F.A. Scholten, Walter J.B. Mastboom, Istvan Vermes, Arjan G.J. Tibbe, Marco R. De Groot, Leon W.M.M. Terstappen
Pages: 1361-1368 Published online on: 09 January 2015
Article
The tryptophan derivative, tranilast, and conditioned medium with indoleamine 2,3-dioxygenase-expressing cells inhibit the proliferation of lymphoid malignancies
Shihoko Suwa, Aya Kasubata, Miyu Kato, Megumi Iida, Ken Watanabe, Osamu Miura, Tetsuya Fukuda
Pages: 1369-1376 Published online on: 09 January 2015
Article
SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity
Soonduck Lee, Jinsun Kim, Samil Jung, Chengping Li, Young Yang, Keun Il Kim, Jong-Seok Lim, Yonghwan Kim, Choong-Il Cheon, Myeong-Sok Lee
Pages: 1377-1384 Published online on: 13 January 2015
Article
Licochalcone A induces apoptosis in malignant pleural mesothelioma through downregulation of Sp1 and subsequent activation of mitochondria-related apoptotic pathway
Ka Hwi Kim, Goo Yoon, Jung Jae Cho, Jin Hyoung Cho, Young Sik Cho, Jung-Il Chae, Jung-Hyun Shim
Pages: 1385-1392 Published online on: 13 January 2015
Article
Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanisms
Dai Tamura, Teruyoshi Saito, Kanae Murata, Masafumi Kawashima, Ryuji Asano
Pages: 1393-1404 Published online on: 08 January 2015
Article